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Neuro-COVID: With the ever growing neurological complications being reported from not only newly infected COVID-19 patients but more so from so called ‘recovered’ COVID-19 patients, numerous medical professionals are calling for the international community to recognize Neuro-COVID as a new disease that needs to be handled differently and also for more healthcare professionals to recogn...
Source: COVID-19 Questions Aug 02, 2020 4 years ago
COVID-19 Questions: A question that has been circulating since March to now is whether or not the SARS-CoV-2 coronavirus could remain dormant in the human body or even conceal itself just like in the case of the HIV virus.
Before the question is even attempted to be answered, one has to look into what actually constitutes a recovery in the case of the COVID-19 disease.
According to...
Source: COVID-19 Mutations Aug 01, 2020 4 years ago
COVID-19 Mutations: A highly innovative machine learning model developed by researchers at Michigan State University that first indicated in June (https://arxiv.org/abs/2005.14669) that mutations to the SARS-CoV-2 genome have made the virus more infectious has once again raised the alarms that its platform is indicating that more mutations are occurring on the SAR-CoV-2 genome especially wit...
COVID-19 Drugs: Researchers from Texas A & M University, University of Texas-Galveston and the University Of North Texas have identified a series of potent enzyme inhibitors that are able to suppress SARS-CoV-2 replication by interfering with one of the primary viral proteases.
The researchers urge rapid clinical and preclinical testing of their most potent compounds to meet the need ...
Source: Toxoplasma Gondii Aug 01, 2020 4 years ago
Toxoplasma Gondii: A new discovery from the University of Virginia School of Medicine (UVA) indicates that more than two billion people are infected with a brain parasite spread by cats and contaminated meat, but most will never show symptoms and the research findings could have important implications for brain infections, neurodegenerative diseases and autoimmune disorders.
The study...
Source: COVID-19 Diagnostics Aug 01, 2020 4 years ago
COVID-19 Diagnostics: The American National Institutes of Health is investing up to US$248.7 million in new technologies to address challenges associated with COVID-19 testing (which detects SARS-CoV-2 coronavirus).
The Quidel Sofia SARS Antigen FIA test kit is for use in point-of-care
settings, such as a doctor’s office or pharmacy. Credit: Quidel
The NIH’...
Source: COVID-19 Research Aug 01, 2020 4 years ago
COVID-19 Research: According to a team of Canadian researchers from the University of Alberta, a newly discovered mechanism at work in human immunodeficiency virus (HIV) patients may also lead to new treatments for COVID-19. The Canadian study reveals how HIV attacks peroxisomes, organelles found in all cells that help regulate the immune system, lipid metabolism and cardiovascular health, br...
Source: COVID-19 Medical News Aug 01, 2020 4 years ago
COVID-19 Medical News: According to a new study by audiologists from the University of Manchester, a significant number of patients reported a deterioration in their hearing when questioned eight weeks after discharge from a hospital admission for COVID-19.
The study which is supported by the NIHR Manchester Biomedical Research Center (BRC) was published in the International Journal of Au...
Source: Bacterial Pathogens Jul 31, 2020 4 years ago
Bacterial Pathogens: A first ever landmark study using next-generation technology to comprehensively examine contaminants in oysters in Myanmar reveals alarming findings including the widespread presence of human bacterial pathogens and human-derived microdebris materials, including plastics, kerosene, paint, talc and milk supplement powders.
The research led by scientists from the University o...
Source: Remdesivir And COVID-19 Jul 31, 2020 4 years ago
Remdesivir And COVID-19: Remdesivir that drug that has no proven antiviral properties nor proper credible studies to show how it really works except that it shortens hospitalization stays and was granted approval to treat COVID-19 by the US FDA under the Trump Administration is now coming under the spotlight again and we expect that this will not be the only concerns raised as feedback is coming i...
Source: Australia COVID-19 News Jul 31, 2020 4 years ago
Australia COVID-19 News : The Australian state of Victoria and the nation's second-biggest city Melbourne are being considered for tighter restrictions by authorities as it was reported on Friday that hundreds more coronavirus cases were recorded despite more than three weeks in lockdown.
Despite the fact that greater Melbourne passed the halfway point of a lockdown initially intended...
COVID-19 Alerts: Multisystem Inflammatory Syndrome (MIS) which a condition typically only found in children with COVID-19 and exhibiting Kawasaki disease likeness is now being seen even in younger adults with COVID-19.
In a sobering case, the autopsy findings in a young COVID-19 patient who seemed to be recovering, then rapidly deteriorated and died, showed vasculitis of the small vessels...
Source: COVID-19 And Children Jul 31, 2020 4 years ago
COVID-19 And Children: A new study by researchers from Ann & Robert H. Lurie Children’s Hospital-Chicago and Northwestern University Feinberg School of Medicine-Chicago have found that young children under age 5 with mild to moderate COVID-19 had high amounts of SARS-CoV-2 in their upper respiratory tract versus adults or older children.
The research findings were published in t...
COVID-19 Latest: Doctors at Cambridge University Hospital NHS Foundation Trust have reported that a significant proportion of patients with severe COVID-19 disease who required intensive care developed unanticipated disabling neurological deficits that were related to a neurological condition known as mononeuritis multiplex.
The research findings are published on a preprint server and are...
COVID-19 Drugs: Most people have a fallacy that tetracyclines only work as antibiotics without knowing that these drugs also possess immunomodulatory and anti-inflammatory properties as well.
The SARS-Cov-2 coronavirus seems to attack the human airway epithelium primarily. In severely affected patients, the illness progresses to hypoxemic respiratory failure and acute respiratory distress...
Coronavirus News: An international research team of Chinese, European, and U.S. scientists, say that the SARS-CoV-2 lineage responsible for the COVID-19 pandemic has been circulating in bats for 40–70 years and likely includes other viruses with the ability to infect humans. This finding, which is derived from a newly constructed evolutionary history of SARS-CoV-2, has implications for the p...
Source: COVID-19 And Tocilizumab Jul 30, 2020 4 years ago
COVID-19 And Tocilizumab: Thailand Medical News EXCLUSIVE-While PR companies employed by certain pharma giants to hush up their failures are currently busy; we at Thailand Medical News are adopting the ‘rebel boy attitude’ for another pharma exposé.
The extremely expensive immunosuppressive Tocilizumab or Actemra which was heavily touted by many researchers and doctors ...
Source: COVID-19 Research Jul 30, 2020 4 years ago
COVID-19 Research: German researchers from Goethe University, University Hospital Frankfurt and Max Planck Institute of Biophysics have discovered a compound to inhibit the SARS-CoV-2 coronavirus from using human host cells to produce the vital protein called PLpro, hence blocking the virus replication processes and also strengthening the anti-viral immune response at the same time as it has been ...
COVID-19 Warning: According to researchers from Maine Medical Center- Portland and Tufts University Scholl of Medicine-Boston, COVID-19 may increase the risk of blood clots in women who are pregnant or taking estrogen with birth control or hormone replacement therapy.
It has already been observed that one of the many complications of COVID-19 is the formation of blood clots in previo...
COVID-19 News: Researchers from John Hopkins Medical School including a team of otolaryngologists and pathologists has confirmed that SARS-CoV-2 coronavirus that causes COVID-19 can colonize the middle ear and mastoid region of the head behind the ear.
The medical report was published in the journal: JAMA Otolaryngology. (a journal of the American Medical Association.)
https://jamanetwork...
Source: COVID-19 Hand Sanitizers Jul 29, 2020 4 years ago
COVID-19 Hand Sanitizers: The U.S. FDA (Food and Drug Administration) is warning consumers not to use alcohol-based hand sanitizers containing methanol, or wood alcohol, which is used in fuel and antifreeze and is toxic if absorbed through the skin or life-threatening if ingested.
Furthermore most of these products were found to be not effective against the SARS-CoV-2 coronavirus, further...
Source: Lungs And Pulmonology Jul 29, 2020 4 years ago
Lungs and Pulmonology: A new study led by researchers from University Of California-Los Angeles Children’s Discovery and Innovation Institute and involving numerous other institutions reveals how aging can cause lung regeneration to go awry, which can potentially lead to lung cancer and other diseases. The condition also increases susceptibility to other pathogens including various...
COVID-19 Drugs: Researchers from the Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.
The protein Dornase alfa (proprietary name Pulmozyme from Genentech) is a h...
Source: COVID-19 Vaccines Jul 29, 2020 4 years ago
COVID-19 Vaccines: Research scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health report that two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2.
 ...
Source: COVID-19 Severity Jul 29, 2020 4 years ago
COVID-19 Severity: A new Irish study led by researchers from University College Dublin and with other institutions involved have discovered the presence of circulating platelets with a unique hyperactive phenotype in COVID-19 patients.
The research findings published on a preprint server and yet to be peer-reviewed reports a bidirectional relationship between COVID-19 and coagulation abno...
Source: U.S. Medical News Jul 28, 2020 4 years ago
U.S. Medical News: A novel hospital workforce estimator developed by the Fitzhugh Mullan Institute for Health Workforce Equity (Mullan Institute) at the George Washington University Milken Institute School of Public Health (Milken Institute SPH) shows that 11 American states with surging COVID-19 rates are currently at risk of straining their supply of intensivists, doctors who are trained to work...
Source: Vietnam COVID-19 News Jul 28, 2020 4 years ago
Vietnam COVID-19 News: Vietnam that had so far been largely protected from the ravages of the COVID-19 crisis and has for a record time reported no local transmissions surprisingly today (28th July) locked down its third-largest city for two weeks after 15 cases of COVID-19 were found in a hospital according to local health officials.
It was announced that public transport into and out of...
Source: China COVID-19 News Jul 28, 2020 4 years ago
CHINA COVID-19 News: A COVID-19 cluster in a port city of Dalian in northeast China has spread to other provinces and prompted fresh restrictions, health authorities said Tuesday, as Beijing scrambles to prevent a second wave of infections.
Although China had largely brought the virus under control since it first emerged in the country late last year, through a series of strict lock...
COVID-19 Drugs: Researchers from Yale School of Medicine and the biopharmaceutical firm AI Therapeutics have launched a multi-institutional clinical trial of a drug for treating COVID-19.
The drug known as LAM-002A (apilimod), has a proven safety record. Preliminary research has shown it can block cellular entry and trafficking of the SARS-CoV-2 virus, the cause of COVID-19.
Past t...
ASCO: The American Society of Clinical Oncology, Inc. (ASCO®) is proud to announce the appointment of Dr Jonathan W. Friedberg, MD, MMSc, as the next editor-in-chief of the Journal of Clinical Oncology (JCO), the flagship journal of the American Society of Clinical Oncology (ASCO).
Dr Jonathan W. Friedberg, MD, MMSc
Credit:University of Rochester Medical Center
The Journal o...
Source: COVID-19 Supplements Jul 28, 2020 4 years ago
COVID-19 Supplements: A new Israeli research has again confirmed that Vitamin D plays a very important role in the COVID-19 disease. In this new research it was found that low Vitamin D levels in blood plasma was a risk factor for contracting the COVID-19 disease.
The research findings were published in The FEBS Journal. https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.15495
&nbs...
Source: COVID-19 Immunology: Jul 28, 2020 4 years ago
COVID-19 Immunology: According to a new study by researchers from Yale University and Howard Hughes Medical Institute, the differing immune system responses of patients with COVID-19 can help predict who will experience moderate and severe consequences of disease.
The study findings may help identify individuals at high risk of severe illness early in their hospitalization and suggest dru...
Source: COVID-19 Detection Jul 27, 2020 4 years ago
COVID-19 Detection: According to a new German study led by researchers from University of Veterinary Medicine Hannover, trained dogs can sniff out coronavirus infections.
The research team said that dogs have smell receptors up to 10,000 times more powerful and accurate than humans. That allows certain trained dogs to sniff out diseases like cancer, malaria and ...
Source: COVID-19 Research Jul 27, 2020 4 years ago
COVID-19 Research: Researchers from Italy, Belgium and America in a new collaborative study have found the possible causes of numerous COVID-19 patients who never had diabetes before and were healthy prior to contracting the SARS-CoV02 coronavirus suddenly developing diabetes. According to their research findings, the pancreatic islet beta cells which produce insulin could be infected by the...
Source: World COVID-19 News Jul 27, 2020 4 years ago
World COVID-19 News: China this morning reported its highest number of coronavirus cases in three months, part of a worrying swell of second and third-wave infections that are hitting Asia and Europe. China where the coronavirus was first reported in December last year recorded 61 cases on Monday, the highest daily figure since April.
The new second-wave surge was propelled by clusters in...
Source: U.S. COVID-19 News Jul 27, 2020 4 years ago
U.S. COVID-19 News: Thai media yesterday reported that the United States Embassy In Bangkok, Thailand had send thousands of boxes of protective mask to the province of Chiang Rai province for distribution to Thai hilltribe individuals.
US embassy offcials in Thailadn donating protective mask to Thais.
Photo Credit: US Embassy, Bangkok
This was shocking news for the teams at Thailand Medic...
Source: U.S. COVID-19 News Jul 27, 2020 4 years ago
U.S. COVID-19 News: The exponential rise in COVID-19 cases are forcing more and more hospitals in affected states to start setting up “death panels” to decide who lives and who dies as there is a growing shortage of resources, ICUs, ventilators and other medical resources in many hospitals.
Certain counties are resembling third world countries and trump supporters and Republic...
Myopathy: Although statins are commonly prescribed to millions of individuals globally to reduce their risks of suffering heart attacks and strokes, many alsos develop myopathy as a result of taking these drugs.
Now, researchers from the University of Oxford, in collaboration with other researchers, have identified a combination of factors that put some patients at higher risk of my...
Source: AMD Or Age-Related Macular Degeneration Jul 26, 2020 4 years ago
AMD or Age-Related Macular Degeneration: Researchers from Sanford Burnham Prebys Medical Discovery Institute have shown that the blood protein vitronectin is a promising drug target for dry age-related macular degeneration (AMD), a leading cause of vision loss in Americans 60 years of age and older.
The new study, published in the journal: Proceedings of the National Academy of Scien...
COVID-19-Latest: A study led by Boston Children's Hospital has found that the SARS-CoV-2 coronavirus spike proteins bind to human cells via the ACE2 receptor and then dramatically change shape, jack-knifing to fuse the cell membrane with the coronavirus's outer membrane and opening the door to coronavirus infection.
The study for the first time freeze-frames the spike protein i...
Source: COVID-19 Clinical Care Jul 26, 2020 4 years ago
COVID-19 Clinical Care: A recent study published in American Journal of Roentgenology (AJR),indicates that lung ultrasound (US) was highly sensitive for detecting abnormalities in patients with COVID-19 disease, with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features. https://www.ajronline.org/doi/10.2214/AJR.20.23513
The usage of l...
Source: COVID-19 Vaccine News Jul 26, 2020 4 years ago
COVID-19 Vaccine News: Dynavax Technologies, a fully-integrated biopharmaceutical based in California has partnered with Taiwan-based Medigen Vaccine Biologics to develop a new adjuvanted Covid-19 vaccine candidate.
The new collaborative vaccine development will leverage on Medigen’s stable prefusion form of the SARS-CoV2 recombinant spike protein in combination with Dynavax&rs...
COVID-19 News: Researchers from Singapore’s Duke-NUS Medical School have discovered SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients and in uninfected individuals as well. The Singapore study shows that SARS-CoV-2-specific T cells are present in all recovered COVID-19 patients and interestingly these T cells were also found in all subjects who recovered f...
Source: COVID-19 Antibodies Jul 26, 2020 4 years ago
COVID-19 Antibodies: A new study led by scientists from Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.
By reviewing data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID-19 patients over the past few months, the r...
COVID-19 Drugs: Researchers from Rensselaer Polytechnic Institute-New York, Korea Research Institute of Bioscience and Biotechnology, and Zhejiang University of Technology-China in study involving the test of antiviral effectiveness against the virus that causes COVID-19, found that an extract from edible seaweeds called fucoidan substantially outperformed remdesivir, the current standard antivira...
Source: COVID-19 Diagnostics Jul 25, 2020 4 years ago
COVID-19 Diagnostics: Korean researchers in a new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.
The researchers suggest that a...
Source: COVID-19 Research Jul 25, 2020 4 years ago
COVID-19 Research: A study led by researchers at Karolinska Institutet published in Emerging Microbes & Infections gives new insights into the virus-host interplay enabling newer perspectives about how to tackle the virus. https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1799723
The prevailing COVID-19 pandemic caused by the novel coronavirus has created an unprecede...
Source: COVID-19 Innovations Jul 25, 2020 4 years ago
COVID-19 Innovations: Scientists from George Washington University (GW) have developed a miniscule device that could allow public health professionals to immediately diagnose and track COVID-19 infection using cell phones.
The university’s Technology Commercialization Office (TCO) awarded a US$50,000 COVID-19 Technology Maturation Grant to the team, led by Dr Mona Zaghloul and...
Source: COVID-19 Research Jul 25, 2020 4 years ago
COVID-19 Research: Researchers from the Pennington Biomedical Research Center at Louisiana State University System have established a possible link between the hormone Leptin and the increased risk of severity and mortality in obese COVID-19 patients.
Leptin is a hormone that connects the body's metabolism and immune response system and it may explain why the COVID-19 idisease is so d...
Source: COVID-19 Genomics Jul 25, 2020 4 years ago
COVID-19 Genomics: Research in Netherlands led Radboud University Medical Center-Nijmegen have uncovered that host variants of the X chromosomal gene called TLR7 could be one of the factors that leads to severity in COVID-19 patients.
The research findings were published in the JAMA journal. https://jamanetwork.com/journals/jama/fullarticle/2768926
Present observations suggest that...
Source: COVID-19 Genomics Jul 24, 2020 4 years ago
COVID-19 Genomics: Researchers from the University of Texas Health Science Center at San Antonio (UT Health San Antonio) have discovered how the non-structural protein 16 (nsp16) of the SARS-CoV-2 , in conjunction with nsp10, methylates the 5′-end of virally encoded mRNAs to mimic cellular mRNAs, thus protecting the virus from host innate immune restriction.
The research findi...
Source: COVID-19 Pandemic Jul 24, 2020 4 years ago
COVID-19 Pandemic: The world is about 6 months (Note that on January 23, 2020, WHO chief Tedros publicly described the spread of the new coronavirus in China as “limited.”, and only on January 30, 2020,The World Health Organization finally declares it an international health emergency but not a pandemic just yet) into the COVID-19 pandemic and to date, we have officially more than...
Medicine Alert: Pennsylvania State University researchers along with scientists from La Jolla Institute for Immunology-California and Weill Cornell Medicine-Qatar, have found that in rats and human cells in vitro, LCCBs cause changes in blood vessels known as vascular remodeling that reduce blood flow and increase pressure and could potentially lead to heart failure.
The study finding...
Source: COVID-19 Diagnostics Jul 24, 2020 4 years ago
COVID-19 Diagnostics: Israeli biotech company, Nanoscent has developed a SARS-CoV-2 coronavirus breathalyzer test that gives results in less than 30 seconds, billing it as a "front line" tool that can help restore a sense of normality during the pandemic.
The breathalyser is not meant to replace lab tests, but is a mass screening tool
The company said an extensive trial in Israe...
Source: COVID-19 Research Jul 24, 2020 4 years ago
COVID-19 Research: Scientists from the Rockefeller University-New York, New York Blood Center, Università della Svizzera italiana,-Switzerland and Howard Hughes Medical Institute have discovered in a new study that mutated SARS-Cov-2 spike protein variants can evade neutralizing antibodies .
Furthermore the researchers warn that the emergence of antibody-resistant SARS-CoV-2 varian...