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Source: Thailand Medical News  Dec 10, 2019  5 years ago
Pharma News The global HIV specialists pharma company, ViiV Healthcare, majority owned by GSK, with Pfizer and Shionogi Limited as shareholders, has filed a New Drug Application in the US for fostemsavir, an investigational, first-in-class attachment inhibitor for the treatment of HIV-1 infection. Fostemsavir, the drug is being developed for use in combination with other antiretroviral agents ...
Source: Thailand Medical News  Dec 10, 2019  5 years ago
Phase II of a multi-institutional, study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called enasidenib (ENA) measurably boosts complete remission in patients newly diagnosed with a specific form of acute myeloid leukemia (AML). Study results from the randomized, open-label study were presented at the recently he...
Source: Thailand Medical News  Dec 10, 2019  5 years ago
MR Guided Focused ultrasound is a safe and effective way to target and open areas of the blood-brain barrier, potentially allowing for new treatment approaches to Alzheimer's disease, according to initial study results presented at the recent annual meeting of the Radiological Society of North America (RSNA). Presently, there is no effective treatment for Alzheimer's disease, the most c...
Source: Thailand Medical News  Dec 10, 2019  5 years ago
Oncologists who treat patients with the aggressive triple negative breast cancer have two new ways to predict which cancer patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide. Oncology researchers from the SWOG Cancer Research Network, a cancer clinical trials network funded by the National Canc...
Source: Thailand Medical News  Dec 10, 2019  5 years ago
Researchers from the Developmental and Stem Cell Biology Department at the Institut Pasteur have concluded a study that sheds light on the mechanisms of senescence, by identifying a key protein known as CSB that associated with ageing. Currently, ageing is a dramatic public health issue in the face of the current demographic changes: the proportion of 60 and over in the world's population w...
Source : Thailand Medical News  Dec 10, 2019  5 years ago
Medical researchers from Wake Forest School of Medicine, North Carolina have identified a dead probiotic that reduces age-related leaky gut and inflammation in older animal models. The results from the study is published in the journal GeroScience. Past research has indicated that leaky gut, in which microbes and bacteria in the gut leak into the blood stream through holes or cr...
Source: Thailand Medical News  Dec 10, 2019  5 years ago
Researchers from University of Texas Health Science Center, San Antonio along with medical scientists from Florey Institute for Neuroscience and Mental Health in Melbourne have discovered an inflammatory biomarker called sCD14 that is related to brain atrophy, cognitive decline and dementia, according to a study of more than 4,700 participants from two large community-based heart studies. The stud...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
Approximately 26 million people globally  have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 470,000 new cases are diagnosed each year. IBD patients suffer from pain, extreme discomfort, and many other symptoms caused by continuously relapsing and remitting inflammatory lesions in the layer of cells that lines the intestinal ...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
Imperial College London researchers have shown how the chaotic electrical signals underlying irregular heart rhythms lead to the failure of standard treatments. By modelling how electrical signals on the inside and the outside of the heart move across the muscle, the researchers  have suggested why corrective surgery is not currently always beneficial. The new insight could improve surgery...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
In a joint study conducted by researchers from Harvard University and University of Tokyo, it was found that even light to moderate alcohol consumption was associated with elevated cancer risks in Japan. In the study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the overall cancer risk appeared to be the lowest at zero alcohol consumption. In the...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
First it was Philippines in the later part of the year, now Malaysia too is witnessing cases of polio re-emerging in its country after almost 27 years. Malaysia has reported its first polio case in 27 years, health authorities said yesterday, announcing a three-month-old baby had been diagnosed on Borneo island. Malaysian health ministry's director-general, Dr  Noor Hisham Abdullah, sa...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
Many of you may be familiar with the newly found fact that your gut and skin are home to a collection of microbes ranging from fungi, bacteria and viruses, that are vital for keeping you healthy. But how many of you are aware that your eyes are also host a unique menagerie of microbes? Collectively, they are called  the eye microbiome. It has been discovered that when these microbes are out o...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
Both neurodegenerative diseases, Parkinson’s Disease and Multisystem Atrophy (MSA) are associated with the accumulation of alpha-synuclein proteins in the brain. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Max Planck Institute for Biophysical Chemistry (MPI-BPC) have investigated the molecular makeup of these protein deposits finding structural diversity. E...
Source: Thailand Medical News  Dec 09, 2019  5 years ago
An individual’s risk of developing cancer is affected by genetic variations in regions of DNA that don’t code for proteins, previously dismissed as ‘junk DNA’, according to new research published in the British Journal of Cancer last week. Professor Dr John Quackenbush, from Harvard T.H. Chan School of Public Health and lead author of the study told Thailand Me...
Source : Thailand Medical News  Dec 09, 2019  5 years ago
A team of Stanford University School of Medicine scientists have developed a new blood diagnostic platform that functions as a kind of physiological clock: monitoring the levels of 373 proteins circulating in one’s blood. If the protein levels are out of the recommended levels, it can indicate critical issues about a person’s health and stage of biological aging. Dr Tony Wyss-Coray,...
Source: Thailand Medical News  Dec 08, 2019  5 years ago
A must for every hospital, Siemens Healthineers has released a couple of AI-driven and cloud-based software applications, one for the brain and one for the prostate, that automate a great deal of the manual tasks that radiologists have to perform. Both of the applications can be used with data coming from any MRI machine, so they can be deployed by just about any facility using an MRI scanner and...
Source: Thailand Medical News  Dec 08, 2019  5 years ago
Isolating patients with otherwise stable coronary artery disease (CAD) who are high-risk and would benefit from more intense or invasive interventions is currently a major theme in cardiology research. Often CAD patients undergo a treadmill exercise test to look for signs of blockages in their coronary arteries, and Emory researchers have been examining measurements that could provide additional i...
Source: Thailand Medical News  Dec 08, 2019  5 years ago
Of the 46 different brands of metformin, a diabetes medication that is available in most South-East Asian countries, three versions are being recalled after they were found to contain unsafe levels of an impurity called NDMA that can potentially cause cancer. The Singapore Health Sciences Authority (HSA) tested all 46 locally marketed metformin medicines and the remaining 43 are not affected. The...
Source : Thailand Medical News  Dec 07, 2019  5 years ago
A new research by University of Liverpool warns that common first-line treatment approach of using fluconazole for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance. The study findings highlight the need to develop new drugs and treatment regimens for the lethal brain infection, which kills around 180,000 people each year. The results fi th...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
It’s the next wave, cultured meats or in vitro meat, also called "clean meat" by its supporters, is meat produced in a laboratory using bioengineering techniques that will be appearing in supermarkets and restaurants as early as 2020. Dr Mark Post, professor at Maastricht University, presented the first hamburger in 2013 made of cultured meat. ...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
Presently, colorectal cancer is the second most common type of cancer worldwide, with about 90% of cases occurring in people 50 or older. Arising from the inner surface, or muscosal layer, of the colon, cancerous cells can penetrate through the deeper layers of the colon and spread to other organs. Left untreated, the disease is fatal. Conventional colon cancer screening is performed by flexibl...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
Researchers from the University of Texas MD Anderson Cancer Center have demonstrated in a new study that after receiving acupuncture treatment three days a week during the course of radiation treatment, head and neck cancer patients experienced less dry mouth or xerostomia conditions. The clinical trial results, published in JAMA Network Open, is the first randomized, placebo-controlled, P...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
Though traditionally, Multiple Sclerosis has always been a sickness associated with adults, doctors worldwide are witnessing a phenomena of more teenagers especially girls developing the disease over the last 6 years especially in developed countries. Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system a...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
Researchers From Southern Methodists University (SMU) have discovered that the drug oleandrin derived from the Nerium oleander plant could prevent the HTLV-1 virus from spreading by targeting a stage of the reproduction process that is not currently targeted by existing drugs. This is significant discovery because there is currently no cure or treatment for the virus of a lesser-known "c...
Source: Thailand Medical News  Dec 07, 2019  5 years ago
In Asian populations, despite biliary tract cancer being a type of cancer that is considered rare globally, its growing incidence rate is becoming a worrisome trend. In countries like Thailand, Cambodia, Vietnam, Myanmar, China, Korea and Japan, the incidence of bile duct cancer has been rising at an exponential rate. Currently Thailand* has the highest incidence rate in the world with an estimate...
Source: Thailand Medical News  Dec 06, 2019  5 years ago
A new research suggests it's about time to consider that possibility that a clock could do  a better job than a scale at promoting weight loss, improving sleep and preventing diabetes. By exploring the benefits of daily fasting in humans, researchers have found that people who are at high risk of developing diabetes improved their health in myriad ways when they ate all of their meals ov...
Source: Thailand Medical News  Dec 06, 2019  5 years ago
Medical Scientists from 22 prestigious institutions, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide. Chronic Inflammation leads to a varierty of medical conditionsincluding neurodegenerative disease, cancer, autoimmune issues, etc. The collective group of international experts, which also includ...
Source: Thailand Medical News  Dec 06, 2019  5 years ago
According to a study published in JAMA Network Open, Aspirin use three or more times per week is associated with reductions in all-cause, any cancer, gastrointestinal cancer, and colorectal cancer (CRC) mortality among older adults. Dr Holli A. Loomans-Kropp, Ph.D., M.P.H., from the National Cancer Institute in Rockville, Maryland, and colleagues examined the correlation of aspirin use wit...
Source: Thailand Medical News  Dec 06, 2019  5 years ago
Thailand HIV News By reengineering a peptide called CP24, the new compound called  IBP-CP24 has the potential to be further developed as a long-acting anti-HIV drug that can be used alone or in combination with a broad neutralizing antibody for the treatment and prevention of HIV-1 infection, according to a study published December 5 in the open-access journal PLOS Pathogens by Lu ...
Source : Thailand Medical News  Dec 06, 2019  5 years ago
Heart health impact by sugars depends on the dose and type of sugar consumed, suggests a new study led by researchers at St. Michael's Hospital. The research team, led by Dr. John Sievenpiper, a staff physician in the Division of Endocrinology and Metabolism and a scientist at the Li Ka Shing Knowledge Institute, examined the relationship between total and added sugars that contain fructose...
Source : Thailand Medical News  Dec 06, 2019  5 years ago
-Real exposure levels to the endocrine disruptor and carcinogenic chemical could be as could be as high as 44 times more, raising questions as to whether it was a deliberate attempt. Washington State University researchers have developed a more accurate method of measuring bisphenol A (BPA) levels in humans and found that exposure to the endocrine-disrupting chemical is far higher than previous...
Source: Thailand Medical News  Dec 06, 2019  5 years ago
Individuals with nonalcoholic steatohepatitis (NASH), a chronic liver disease and a leading cause for liver transplantation in the world, currently lack an approved drug therapy, but this may soon change. A large Phase III clinical trial designed in collaboration with Virginia Commonwealth University is the first to demonstrate the safety and effectiveness of an oral medication to treat ...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
According to a new study presented yesterday at the annual meeting of the Radiological Society of North America (RSNA), the use of high-dose-rate brachytherapy to treat elderly patients with common skin cancers offers excellent cure rates and cosmetic outcomes. SCC or Squamous cell carcinoma and  BCC or basal cell carcinoma are the most common types of skin cancer, affecting 3 million Amer...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
The human gut has long been suspected to play a role in autoimmune disease. A research team has now identified evidence of a potential mechanism. Which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal cord is still not understood or known. A potential factor is described by a research team in the journal Procee...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
Typically, inflammation is a hallmark of many health conditions. However, quantifying how the underlying biology of inflammation contributes to specific diseases has been difficult. For the first time, UNC School of Medicine researchers and colleagues now report the development of a new technology to identify white blood cells called neutrophils that are primed to eject inflammatory DNA into the c...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
Though prostate cancer is the most common cancer in men globally, we still have yet to know all of its causes. The largest ever study to use genetics as a measurement for physical activity to look at its effect on prostate cancer, reveals that being more active reduces the risk of prostate cancer. Over 140,000 men were included in the study, of which, 80,000 had prostate cancer. The study, publ...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
Ohio State University Wexner Medical Center researchers   have developed a new "virtual biopsy" that allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives. Conventional standard involves testing the fluid inside the cysts. It correctly identifies them as benign or...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
Research led by Dr Han-Wei Zhang of China Medical University, Taiwan shows that long-term exposure to hydrocarbons in the air is a risk factor for ischemic stroke development. The study findings has been  published the open-access journal PLOS ONE yesterday. Past studies have demonstrated a link between cardiovascular diseases and increased levels of ozone and airborne particulat...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
A recent study conducted by scientists from the US National Institute of Health found that females who use permanent hair dye and chemical hair straighteners have a higher risk of developing breast cancer than women who don't use these products. The study published online Dec. 4 in the International Journal of Cancer and shows that breast cancer risk increased with more frequent u...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
The incidence of heart failure globally is about 39.4 million cases per year and is a leading driver of health care costs in the world. The "stiff heart" heart failure variant accounts for about half of all cases and the vast majority of such patients take beta-blocker medications despite unclear benefit from their regular use. A new medical publication in JAMA ( The Journal of...
Source: Thailand Medical News  Dec 05, 2019  5 years ago
A breakthrough clinical approach has been developed combining new diagnostic techniques to detect a leaking blood-brain barrier (BBB) with a new anti-inflammatory drug that for the first time slows or reverses age-related cognitive decline. In two related studies published in the journal Science Translational Medicine, researchers from Ben-Gurion University of the Negev (BGU) and the Universi...
Source : Thailand Medical News  Dec 05, 2019  5 years ago
MIT medical researchers have developed an oral contraceptive that only has to be taken once a month, which could reduce unintended pregnancies that result from forgetting to take a daily dose. This kind of monthly contraceptive could have a significant impact on the health of women and their families, especially in the developing world, the researchers say. Currently, oral contraceptives a...
Source: Thailand Medical News  Dec 04, 2019  5 years ago
A Phase 11 clinical trial involving a pioneering precision medicine already licensed for breast and ovarian cancer can also slow or stop tumour growth in some men with advanced prostate cancer. The recently concluded phase II trial found that over 80 per cent of men with prostate cancer whose tumours had mutations in the BRCA genes responded well to treatment with the target...
Source: Thailand Medical News  Dec 04, 2019  5 years ago
The controversial gene editing performed on Chinese twins last year meant to immunize them against HIV may have failed in its purpose and created unintended mutations, scientists said yesterday after the original research was made public for the first time.  Dr He Jiankui  Selected excerpts from the manuscript were released by the MIT Technology Review for the purpose of showing how C...
Source: Thailand Medical News  Dec 04, 2019  5 years ago
Medical researchers at Karolinska Institutet have developed an online cognitive behavioral therapy (CBT) program for the difficult-to-treat pain syndrome fibromyalgia. In her doctoral thesis, Maria Hedman-Lagerlöf shows that patients who receive the treatment experience fewer symptoms and enjoy better quality of life. Licensed psychologist Dr Maria Hedman-Lagerlöf, doctoral student at...
Source: Thailand Medical News  Dec 04, 2019  5 years ago
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro de Investigaciones Biológicas (CIB) of the Consejo Superior de Investigaciones Científicas (CSIC) have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease (IBD). The study was led by Dr. Alicia G Arroyo and is published today in EMBO ...
Source: Thailand Medical News  Dec 04, 2019  5 years ago
Cardiovascular (CV) disease has become the leading cause of death worldwide. Vascular regeneration is one of the many  promising treatments for cardiovascular disease. Remodeling the endotheliumi.e., forming a confluent vascular endothelial cell monolayer on the lumen plays a vital role in this process. However, rapid endothelialization poses challenges, however, when using existing ...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
Although there are a number of drugs to treat Attention Deficit Hyperactivity Disorder (ADHD), they can have some pretty serious side effects. Researchers in Singapore at the country’s Institute of Mental Health (IMH), Duke-NUS (National University of Singapore) Medical School, and A*STAR (Agency for Science, Technology and Research), have developed a system that combines neuromonitoring wit...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
An artificial intelligence company based in Florida,Care.ai has partnered with Google to create an autonomous patient monitoring system. By combining multiple sensors in a patient’s room and neural network data analysis, the system can identify and predict accidents and clinical events, in some cases warning healthcare staff before an incident happens.   Typically, preventable acciden...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
Pharma giant, Roche has announced data from its SAkuraSky study, in which the investigational medicine “satralizumab”  formerly SA237 was evaluated for the treatment of neuromyelitis optica spectrum disorder (NMOSD); an inflammatory disorder of the central nervous system. The clinical results of the trial found that only eight of 41 patients (20%) treated with satralizumab in c...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
Currently obesity which affects more than one-third of American adults, is more than just an uncomfortable excess of weight, it is a driver of several, often fatal diseases like high blood pressure, diabetes, asthma, stroke, and congestive health failure, making it one of the most significant public health threats. The cost of treating and managing obesity-related diseases is expected to...
Source : Thailand Medical News  Dec 03, 2019  5 years ago
Typically, embryonic stem cells have the potential to differentiate into any type of cell in the human body. Once differentiated though, the newly minted somatic cells live out the rest of their days as that specific cell type and never again have the capacity to differentiate. Or so the theory goes. A new study published  in Cell Reports, a team led by researchers from the University...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
According to a study published in Neuropsychopharmacology,lLong-term (chronic) treatment with opioids, such as morphine, prior to trauma enhances fear learning in animal models. The findings, which link chronic opioid treatment before a traumatic event with responses to subsequent stressful events, may suggest a possible mechanism underlying the frequent co-occurrence of post-traumatic stress...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
A team of researchers through international collaborations have identified key networks within the brain they say interact to increase the risk that an individual will think about or attempt suicide. The medical researchers say their review of existing literature highlights how little research has been done into one of the world’s major killers, particularly among the most vulnerable grou...
Source: Thailand Medical News  Dec 03, 2019  5 years ago
Emerging evidence has prompted a change in the management of paracetamol poisoning, according the authors of the updated guideline summary published online today by the Medical Journal of Australia. Past guidelines were published by the MJA in 2015 but further research has emerged, particularly regarding acetylcysteine regimens, massive paracetamol ingestions, and modified release paraceta...

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