Anti-aging

Regenerative Medicine On The Horizon With Latest Success Of Rejuvenating Stems Cells From An Aging Brain

Source: University of Luxembourg Mar 04, 2019 6 years ago

Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and from the German Cancer Research Center (DKFZ) have been able to rejuvenate stem cells in the brain of aging mice. The revitalised stem cells improve the regeneration of injured or diseased areas in the brain of old mice. The researchers expect that their approach will provide fresh impetus in r...

Study shows that Centella Asiatica Extract Aids In Memory and other Cognitive Issues.

Source: Oregon Health and Science University Feb 16, 2019 6 years ago

A team of researchers from Oregon Health and Science University has concluded from an extensive study involving a medicinal plant called Centella Asiatica, commonly known as Gotu Kola (in thai: bua bok ) is effective in terms of improving memory especially in the elderly and those afflicted with cognitive related diseases. Centella Asiatica contains a variety of phyto chemicals such ...

PET Scans Shows Hyperbaric Oxygen Therapy Improves Alzheimer’s Disease In The Aged

Source: Louisiana State University Health Sciences Center Feb 03, 2019 6 years ago

Dr. Paul Harch, Clinical Professor and Director of Hyperbaric Medicine at LSU Health New Orleans School of Medicine, and Dr. Edward Fogarty, Chairman of Radiology at the University of North Dakota School of Medicine, report the first PET scan-documented case of improvement in brain metabolism in Alzheimer's disease in a patient treated with hyperbaric oxygen therapy (HBOT). The authors...

Blood test detects brain damage and predicts a decade in advance whether individuals will have Alzheimer's , Dementia or other Neurodegenerative problems.

Source: Washington University School of Medicine Jan 22, 2019 6 years ago

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer’s disease – even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany. The findings, published in Nature Medicine, may one day be ap...

Discovery Of Amyloid Precursor Protein That Modulates Neuronal Signal Transmission May Lead To Cure For Alzheimer.

Source: VIB (the Flanders Institute for Biotechnology) Jan 12, 2019 6 years ago

Alzheimer's-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-β. However, this amyloid-β is a fragment produced from a precursor protein whose normal function has remained enigmatic for decades. A team of scientists at VIB and KU Leuven led by professors Joris de Wit and Bart De Strooper has now uncovered that this amyloid pre...

TGF(Transforming Growth Factor) Beta Inhibitors: Secret To Youth Skin Discovered.

Source: University of California San Diego Jan 01, 2019 6 years ago

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections. Studies by the University of California San Diego School of Medic...

Study shows Minocycline has preventive actions against neurodegenerative diseases during aging.

Source: Scripps Research, US Dec 04, 2018 6 years ago

An antibiotic, minocycline, can increase the lifespan of roundworms by preventing the build-up of proteins during aging, a study in the open-access journal eLife reports. Protein aggregation causes several progressive age-related brain diseases, including amyotrophic lateral sclerosis, Alzheimer's, Parkinson's and prion disease. This study shows that minocycline prevents this bu...

Hormone replacement therapy in women associated with lower early mortality

Source: American College of Cardiology Nov 06, 2018 6 years ago

Women using hormone replacement therapy to relieve the symptoms of menopause faced a lower risk of death and showed lower levels of atherosclerosis, or plaque buildup in the heart's arteries, compared to women not using hormone therapy, according to a single-center study scheduled for presentation at the American College of Cardiology's 66th Annual Scientific Session. Hormone replacemen...

Inflammation in neurodegenerative diseases may be reduced by regulating microglial immune cells activity

Source: Massachusetts General Hospital Oct 24, 2018 6 years ago

A group of Massachusetts General Hospital (MGH) investigators is proposing that targeting immune checkpoints -- molecules that regulate the activity of the immune system -- in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). In their review artic...

Brain scan study identifies factors of brain aging

Source: Journal of Alzheimer's Disease Sep 06, 2018 6 years ago

In the largest known brain imaging study, scientists from Amen Clinics (Costa Mesa, CA), Google, John's Hopkins University, University of California, Los Angeles and the University of California, San Francisco evaluated 62,454 brain SPECT (single photon emission computed tomography) scans of more than 30,000 individuals from 9 months old to 105 years of age to investigate factors that accelera...

Molecular link between aging and neurodegeneration

Source: Harvard Medical School Aug 28, 2018 6 years ago

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases. ...

Study Reveals That Aging can be reversed by “removing wrinkles inside our cells”

Source: University of Virginia Aug 08, 2018 6 years ago

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases—and possibly even turn back the clock on aging itself. Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty ...

Newly discovered Anti-Aging Peptide :pNaKtide

Source: Marshall University Joan C. Edwards School of Medicine Jul 11, 2018 6 years ago

New research from a team at the Marshall University Joan C. Edwards School of Medicine demonstrates that the Na/K-ATPase oxidant amplification loop (NAKL) is intimately involved in the aging process and may serve as a target for anti-aging interventions. The researchers were also able to successfully demonstrate the therapeutic potential of pNaKtide, a synthetic peptide, in improving impaired phys...

AUTOPHAGY (“Cellular Housekeeping”) can help beat age-related diseases

Source: Fierce Biotech Jul 13, 2018 6 years ago

Scientists at UT Southwestern Medical School have spent the last two decades studying autophagy, the process cells use to throw out toxic substances that endanger their health. They discovered autophagy not only helps the body fight off infections, but it also protects against many age-related diseases such as cancer and neurological disorders. Autophagy The findings raised a question: Could b...

Experimental Cancer Drugs Boost Elderly Immune Systems, Raising Hopes For Anti-Aging Effects

Staff Writer, TMN Jul 12, 2018 6 years ago

Scientists on the hunt for anti-aging drugs say they've made an advance with tantalizing potential: Two experimental drugs appear to safely boost the immune systems of elderly humans. The researchers stress that more research is needed to confirm the findings and show the drugs are safe. And at least one researcher says the findings are based on a relatively small number of people and used m...

Low Total Testosterone in Men Widespread, Linked to Chronic Disease

Source: Michigan Medicine Jul 16, 2018 6 years ago

New Research finds that more men have suboptimal testosterone levels than previously known, and it may be putting these men at risk. Testosterone hormone replacement therapy is great tool in preventing diseases associated with aging in men. A male’s total testosterone level may be linked to more than just sexual health and muscle mass preservation, a new study finds. Low amounts of th...

Is the Anti-Aging Pill finally here?

Staff Writer, TMN Jul 03, 2018 6 years ago

A drug derived from an Easter Island bacterium extends the life of lab animals. People could be next. Can a pill make you younger? One of the few drug studies ever carried out in an attempt to address this question was reported by Novartis on Christmas Eve 2017. The company had sought to see whether giving low doses of a drug called everolimus to people over 65 increased their response to flu va...

Reversing Brain Aging Using Magnesium L-Threonate

Staff Writer, TMN Jul 10, 2018 6 years ago

MIT researchers discovered and patented magnesium L-threonate based on its unique ability to boost brain levels of magnesium. Rapid absorption and ability to enter the brain enables this magnesium to structurally reverse certain aspects of brain aging.1-4 A recent human study demonstrates the benefits of magnesium L...

Sleep Disorder Linked to Brain Changes Seen in Dementia

Staff Writer, TMN Jul 08, 2018 6 years ago

Obstructive sleep apnoea has been linked to brain changes seen in the early stages of dementia, University of Sydney research reveals. Published today in The European Respiratory Journal, the study's authors say the finding provides evidence that screening older people for obstructive sleep apnoea (OSA) and providing treatment where needed could help prevent dementia in this po...

Beware! Consuming bacteria-infected milk can trigger rheumatoid arthritis

Staff Writer, TMN Jul 07, 2018 6 years ago

A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a study. Researchers at the University of Central Florida (UCF) in the US have discovered a link between rheumatoid arthritis and Mycobacterium avium subspecies paratuberculosis, known as MAP, a bacteria found in about half the cows i...

Biogen Alzheimer's drug success: A big step because almost every dementia trial before it has ended in failure

Source: CNBC Jul 06, 2018 6 years ago

Biogen announced surprise successful results from an Alzheimer's drug clinical trial that sent shares of the pharmaceutical company soaring. Alzheimer's drug research has been plagued by years of unrelenting failures, leading companies including Pfizer to give up the search for new compounds. Dementia experts have questioned the narrow focus from biotech companies on amyloid ...

3 Promising Anti-Aging Therapies Research

Staff Writer, TMN Jul 03, 2018 6 years ago

Some researchers believe they will soon be able to slow or even stop the body's clock—at least for a little while The majority of older people live out their final years with at least one or two chronic ailments, such as arthritis, diabetes, heart disease or stroke. The longer their body clock ticks, the more disabling conditions they face. Doctors and drug companies traditionally...

Long-sought structure of telomerase paves way for new drugs for aging, cancer

Staff Writer, TMN Jul 04, 2018 6 years ago

Cryo-electron microscopy images reveal details of protein, RNA binding and possible drug-target sites Shown is the space-filling model of human telomerase holoenzyme structure determined by cryo-electron microscopy (cryo-EM). Telomerase catalyzes the synthesis of telomeric DNA (green) at the ends of chromosomes (blue) to compensate for the loss of telomeres during genome replication. The structu...

Anti-aging field 'explodes' in pursuit of healthy old age

Staff Writer, TMN Jul 02, 2018 6 years ago

Experts on the forefront of anti-aging medicine say the field is booming, with therapies on the horizon to target illnesses like cancer and Alzheimer's and make for a healthier, older population in the years to come. Such remedies are increasingly important because of the world's aging population. Growing old, experts say, is a leading risk factor for most human diseases and a majo...

People are getting hand injections to reverse signs of aging

Staff Writer, TMN Jul 01, 2018 6 years ago

Men and women are now opting for hand injections in an effort to turn back time and reverse telltale signs of ageing. For many, hands can be a sign of someone's age - as they are often the first body part to show protruding veins and tendons, lack of skin elasticity, and sunspots. Now, in response to a growing number of people who'll do whatever they can to stay looking ...

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