Arthritis

Ononin Slows Joint Damage in Osteoarthritis Through Key Pathway Modulation

Nikhil Prasad Nov 09, 2024 13 days ago

Herbs And Phytochemicals: Osteoarthritis (OA) is a widespread joint disease marked by the breakdown of cartilage, often resulting in joint pain, stiffness, and loss of movement. As people age, the risk of developing OA increases, making it a significant concern, especially in older populations. With limited treatment options beyond managing symptoms, researchers continually seek alternatives that ...

Swiss study shows that low-iron diet shows promise in reducing symptoms associated with arthritis

Nikhil Prasad Oct 31, 2024 22 days ago

Medical News: In a new breakthrough, researchers from the Department for Rheumatology and Immunology at the University Hospital Bern, Switzerland, have found that a low-iron diet significantly reduced the severity of arthritis in a mouse model of rheumatoid arthritis (RA). The study offers fresh insights into dietary interventions that may benefit those suffering from inflammatory arthritis. ...

New Hope for Treating SARS-CoV-2 Virus-Induced Osteoarthritis

Nikhil Prasad Oct 22, 2024 1 month ago

Medical News: A recent study by a team of researchers from Griffith University in Australia may bring new treatment possibilities for people suffering from virus-induced osteoarthritis. Joint inflammation and pain, long known to accompany various viral infections like SARS-CoV-2, are often underexplored. However, researchers have now uncovered a key mechanism linking viral infections to joint dama...

Galangin shows promise in treating rheumatoid arthritis

Nikhil Prasad Jul 27, 2024 4 months ago

Arthritis News: A collaborative team of researchers from Beirut Arab University, the American University of Beirut, and Abu Dhabi Women’s College has shed new light on the potential treatment for rheumatoid arthritis (RA), a debilitating autoimmune disease affecting millions worldwide. This Arthritis News report delves into their recent findings, which have revealed the promising effects of ...

The role of TRAF1 in rheumatoid arthritis

Nikhil Prasad Jul 21, 2024 4 months ago

Arthritis News: Understanding Rheumatoid Arthritis Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1% of the global population. This debilitating condition primarily targets the joints, leading to inflammation, pain, and eventual destruction of joint tissues. The key players in this process are immune cells, particularly macrophages, which are central to the infl...

Cinnamaldehyde treated exosomes shows promise in treating joint inflammation

Nikhil Prasad Jul 03, 2024 5 months ago

Arthritis News: The Battle Against Osteoarthritis Osteoarthritis (OA) is a common and painful condition that affects millions of people worldwide. It's a type of arthritis that causes the cartilage in your joints to break down, leading to pain, swelling, and reduced movement. Researchers are constantly searching for new ways to treat this condition, and a recent study by researchers from Chon...

Melatonin: A Potential Game-Changer in Arthritis Treatment

Nikhil Prasad Jun 06, 2024 6 months ago

Arthritis Updates: Arthritis, a chronic inflammatory condition affecting millions globally, often leads to debilitating pain and reduced quality of life. Among various types, osteoarthritis (OA) is prevalent, characterized by the degradation of cartilage, inflammation, and pain. Traditional treatments focus on symptom management, but recent research suggests that melatonin, a hormone known for reg...

AI In Medicine: An Artificial Intelligence Model For The Early And Accurate Radiographic Diagnosis Of Joint Diseases

Nikhil Prasad Feb 28, 2024 9 months ago

AI In Medicine: In recent groundbreaking research, scientists have unveiled an artificial intelligence (AI) deep learning model designed to detect early signs of degenerative joint diseases with remarkable accuracy. The study primarily focuses on osteoarthritis of the temporomandibular joint (TMJ), shedding light on the potential applications of AI in revolutionizing radiographic diagnoses for var...

Stem Cells News: U.S. Study Shows That Overpriced Stem Cell Therapies To Treat Knee Pain Are Not As Effective As Ordinary Corticosteroid Injections!

Nikhil Prasad Nov 03, 2023 1 year ago

Stem Cells News: Osteoarthritis (OA) is a debilitating condition that affects millions of people worldwide, resulting in extensive joint damage and chronic pain. Despite the continuous advancements in diagnosis, medications, and short-term pain management solutions, the development of a disease-modifying OA drug has remained a formidable challenge. However, in recent years, stem cell therapy is be...

Arthritis News: Study Finds That Rheumatoid Arthritis Linked to Elevated Risk of Aortic Stenosis!

Thailand Medical News Team Aug 26, 2023 1 year ago

Arthritis News: Rheumatoid arthritis (RA) is a chronic autoimmune disease primarily known for causing joint inflammation and damage. However, a recent study has shed light on a potential connection between RA and an increased risk of aortic stenosis (AS), a condition that affects the heart's aortic valve. This revelation has ignited interest within the medical community, prompting researchers ...

Arthritis News: Novel Antibody Targets Interleukin-17A and F For Rheumatoid Arthritis And Inflammatory Bowel Disease - A Promising Breakthrough

Thailand Medical News Team Aug 24, 2023 1 year ago

Arthritis News: In the realm of medical advancements, the search for innovative therapies that can effectively combat autoimmune diseases like rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) remains a constant challenge. However, a recent breakthrough has shown promising results in this pursuit. Researchers have unveiled a novel antibody, Ab-IPL-IL-17, which targets a specific amino...

Herbs-Phytochemicals: Celastrol From Tripterygium Wilfordii Inhibits Rheumatoid Arthritis Progression By Targeting The COMMD3/8 Complex

Herbs-Phytochemicals - Celastrol - Arthritis Apr 05, 2023 2 years ago

Herbs-Phytochemicals: The immune system plays a vital role in protecting our bodies from infections and diseases. However, sometimes the immune system malfunctions and attacks the body, resulting in autoimmune disorders such as rheumatoid arthritis, Crohn's disease, type 1 diabetes, and celiac disease. A recent study by scientists from Laboratory of Immune Response Dynamics, WPI Immun...

BREAKING! Fumarate Hydratase Discovered As An Enzyme That Holds The Key To Treating Inflammatory Diseases Such As Lupus, Arthritis, Sepsis And COVID-19!

Fumarate Hydratase -COVID-19, Sepsis, Lupus, Arthritis Mar 30, 2023 2 years ago

Fumarate Hydratase: In an effort to understand the progression of inflammatory diseases, researchers at the Trinity Biomedical Sciences Institute's School of Biochemistry and Immunology in Trinity College Dublin have made a significant breakthrough. This new understanding reveals a potential therapeutic target for a variety of inflammatory conditions. The team found that an enzyme cal...

Med News: Stanford Study Find Metformin Use Is Associated With Lower Incidence Of Osteoarthritis

Med News - Metformin - Osteoarthritis Mar 27, 2023 2 years ago

Med News: A new study led by researchers from Stanford University, California-USA that also included scientists from Chinook Therapeutics, Washington-USA and The VA Palo Alto Health Care System, California-USA has found that metformin use is associated with lower incidence of osteoarthritis. Osteoarthritis (OA), the most commonly observed type of arthritis, is associated with considerable...

BREAKING! Colorado Scientist identify New Gut Bacterial Arthritogenic Strain From The Subdoligranulum Genus That Causes Rheumatoid Arthritis!

Source: Medical News - Arthritis Oct 31, 2022 2 years ago

Scientists form the University of Colorado Anschutz Medical Campus – USA have made a startling discovery in which they identified a new strain of gut bacteria from the Subdoligranulum genus that is arthritogenic and able to cause Rheumatoid Arthritis! The study also involved researchers from Stanford University School of Medicine, California - USA and Benaroya Research Institute, Se...

Southern Illinois University Edwardsville Study Finds That Most Exposed To SARS-CoV-2 Will Develop Viral Arthropathy Besides Myalgia

Source: Medical News - Viral Arthropathy - SARS-CoV-2 Oct 07, 2022 2 years ago

A study led by researchers from Southern Illinois University Edwardsville-USA and Hospital Sisters Health System-Illinois-USA has found that a high proportion of the population that has been exposed to the SARS-CoV-2 virus will eventually develop viral arthropathy beside myalgia. Viral arthropathy (viral arthritis) is swelling and irritation (inflammation) of one or more joints parti...

Study Finds That Gout Is A Risk Factor For SARS-CoV-2 infections And COVID-19 Mortality. Women With Gout Have Higher COVID-19 Death Risk Than Men!

Source: Oct 06, 2021 3 years ago

Gout and COVID-19: Researchers from the University of Otago-New Zealand, University of Alabama at Birmingham-USA, University of Queensland-Australia and the University of Auckland-New Zealand have in a new study found that gout is a risk factor for SARS-CoV-2 infections and COVID-19 mortality. The study findings also showed that women with gout have higher COVID-19 death risk than men! The intern...

Patients With Systemic Autoimmune Rheumatic Diseases (SARDs) Are More Prone To More Severe Breakthrough SARS-CoV-2 Infections Warns Harvard Study!

Source: Breakthrough SARS-CoV-2 Infections Aug 12, 2021 3 years ago

The study findings from a new research by medical scientists from Harvard Medical School’s Massachusetts General Hospital-Boston and Brigham and Women’s Hospital-Boston have alarmingly revealed that patients with systemic autoimmune rheumatic diseases (SARDs) despite receiving full doses of the various COVID-19 vaccines are still prone to breakthrough SARS-CoV-2 infections. Alarmingly ...

Erectile Dysfunction: Study Shows That Patients With Gout Have Higher Risk Of Erectile Dysfunction

Source: Erectile Dysfunction Aug 24, 2020 4 years ago

Erectile Dysfunction: A new meta-analysis study by researchers from Guangzhou Medical University, Guangdong-China has reported that the risk of erectile dysfunction in patients with gout was dramatically increased when compared with the general population, suggesting that clinicians should assess erectile function when treating an individual who suffers from gout. The research findin...

BREAKING! Gout And Arthritis: Report Warns That Global Incidences Of Gout Increasing Exponentially

Source: Gout And Arthritis Aug 05, 2020 4 years ago

Gout and Arthritis: According to an analysis published in the Journal: Arthritis & Rheumatology, the prevalence of gout; a form of arthritis characterized by severe pain, redness, and tenderness in joints has increased across the world at an alarming rate from 1990 to 2017 and is still increasing exponentially. https://onlinelibrary.wiley.com/doi/abs/10.1002/art.41404 The research ...

New Breakthrough For Osteoarthritis Treatment Using Drug Combo

Source: Thailand Medical News Jan 27, 2020 5 years ago

Individuals with osteoarthritis, or “wear and tear” arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental drugs reverses the cellular and molecular signs of osteoarthritis in rats as well as in isolated human cartilage cells. Their results were published in the journa...

Swedish Researchers Identify Proteins That Protect Against Rheumatoid Arthritis

Source: Thailand Medical News Jan 22, 2020 5 years ago

A new study from Karolinska Institutet in Sweden, published in the scientific journal PNAS reports that endogenous proteins that play a vital part in allergies and parasitic infection can prevent the immune system from wrongly attacking the body and causing inflamed joints, The medical researchers hope that the results will give rise to new drugs for rheumatoid arthritis. Typically, i...

Transcutaneous Electrical Nerve Stimulation (TENS) May Benefit Women With Fibromyalgia

Source: Thailand Medical News Jan 07, 2020 5 years ago

A simple treatment involving electrical nerve stimulation helped women with fibromyalgia in a recent clinical trial. The findings are published in Arthritis & Rheumatology. Typically, fibromyalgia is characterized by pain and fatigue, particularly during physical activity. Besides widespread pain, individuals with fibromyalgia also have sleep problems. Transcutaneous electrical nerve ...

Emerging Studies Link Antibiotics With Increase the Risk of Arthritis

Source: Thailand Medical News Nov 20, 2019 5 years ago

Rheumatoid arthritis (RA) is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels. An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. The condition is characterized by pain a...

Research Shows That Hip And Knee Steroid Injections Are Dangerous

Source: Thailand Medical News Oct 28, 2019 5 years ago

A new study reveals that commonly given hip and knee steroid intra-articular injections may be harmful in some patients with at-risk conditions or may cause complications that are not well understood. Not only can these injections accelerate arthritis but they can cause joint destruction as well. Boston University School of Medicine (BUSM) researchers have found accelerated arthritis and ...

Warnings Issued About Gout Medications Such As Allopurinol And Febuxostat

Source: Thailand Medical News Sep 30, 2019 5 years ago

Medical Thailand US FDA and other regulatory bodies in Europe and Canada are warning that Allopurinol and Febuxostat used to treat Gout found to be inked to rising number of cardiovascular and kidney incidences. Gout is a common type of arthritis that causes intense pain, swelling, and stiffness in a joint. It usually affects the joint in the big toe. Gout attacks can come on quickly and k...

New Discovery That Antibodies Are The Cause Of Rheumatoid Arthritic Pain

Source: Thailand Medical News Jul 15, 2019 5 years ago

Rheumatoid arthritis is an autoimmune disease that occurs when immune cells attack the cartilage and bone of the joints. The disease affects roughly 1.4 percent of the global population. A common symptom is joint pain, but even before that, the body has started to produce immune antibodies against proteins in the joint. Scientists at Karolinska Institute in Sweden, have now discovered how th...

Rheumatoid arthritis discovery points to new treatment and blood tests

Source: University of Virginia Health System Feb 25, 2019 6 years ago

Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points to a potential new treatment for the autoimmune disorder and may also allow the use of a simple blood test to detect people at elevated risk for developing the condition. The pr...

Stem cell treatments for arthritic knees are unproven and potentially dangerous

Thailand Medical News Feb 16, 2019 6 years ago

Twelve patients who tried injections of stem cells were hospitalized with infections, according to a report in the New York Times that should cause patients concern. More important is that they should investigate stem cell treatments, for conditions such as cartilage injuries to their joints, before committing to one of these procedures. It's also a valuable reminder that physic...

Reversible molecular defect underlying rheumatoid arthritis discovered

Source: Stanford University School of Medicine Feb 06, 2019 6 years ago

In rheumatoid arthritis, immune cells called helper T cells behave differently from their counterparts in healthy cells and in other autoimmune diseases. Stanford scientists have learned why. Stanford University School of Medicine investigators succeeded in countering inflammation and tissue damage caused by rheumatoid arthritis in mice engrafted with human joint-lining tissue and...

Genetic cause of arthritis finally identified

Source: VIB (the Flanders Institute for Biotechnology) Feb 04, 2019 6 years ago

Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team led by Adrian Liston (VIB-KU Leuven) was able to unravel the ...

New approach to treatment that could stop knee and spine osteoarthritis.

Source: Krembil Research Institute Jan 15, 2019 6 years ago

Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks. A team led by Principal Investigator Dr. Mohit Kapoor, Arthritis Research Director at UHN, published the results today in Annals of the Rheumatic Diseases in a paper titled "microRNA-181a-5p antisense oligonucleotide...

Proteins called Galectins Identified as Agents responsible for Cartilage Degeneration in Osteoarthritis

Source: Medical University of Vienna Jan 01, 2019 6 years ago

A type of glycoproteins ie carbohydrate binding proteins, called galectins, plays an important role in the degeneration of cartilage in osteoarthritis. A research group at the Medical University of Vienna was able to demonstrate this correlation, in cooperation with international study partners. In osteoarthritis, certain galectins are produced by the cartilage cells themselves and accelerate the ...

Rheumatoid Arthritis, Lupus and Psoriasis linked to higher risk of Cardiovascular Diseases.

Source: Washington University School of Medicine Dec 07, 2018 6 years ago

People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly. Now, researchers at Washington University School of Medicine in St. Louis believe they have begun to understand the link between the two. Researchers studying mice with a pso...

Ixekizumab, generates promising results in hard-to-treat ankylosing spondylitis

Source: Oregon Health & Science University,Portland Nov 16, 2018 6 years ago

Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis (AS), a chronic inflammatory disease characterized by back pain and sacroiliac-joint damage, may have another treatment option in the biologic drug ixekizumab. The findings will be presented at the American College of Rheumatology's annual meeting in Chicago (Oct...

Blocker Locked Nucleic Acid-Antisense Oligonucleotides (LNA-ASO), Novel Treatment to stop knee and spine osteoarthritis.

Source: Krembil Research Institute Nov 03, 2018 6 years ago

Upadacitinib: New treatment for rheumatoid arthritis

Source: Charité - Universitätsmedizin Berlin Oct 24, 2018 6 years ago

An international research group led by Charité -- Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis. The drug is effective in patients with moderate to severe forms of the disease who have shown an inadequate response to conventional disease modifying drugs. Results from this research have been published in The Lancet. ABBVIE: Upadacitinib ...

Researchers stop cell suicide that worsens sepsis, arthritis

Source: Case Western Reserve University Aug 28, 2018 6 years ago

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death. Cells often perforate their own membranes...

Arthritis severity gene identified

Source: Mount Sinai School Of Medicine Aug 08, 2018 6 years ago

A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition. Through a series of experiments -- on synovial cells from the inner lining of joints in humans...

Novel Biomarker Could Increase Specificity to Diagnosing Rheumatoid Arthritis

Source: University of Tsukuba Jul 22, 2018 6 years ago

While many candidate citrullinated antigens have been identified in rheumatoid arthritis (RA) joints, their involvement in blood serum remains mostly uninvestigated. A new study from the University of Tsukuba-centered set out to explore the expression and commonality of citrullinated proteins in peptide glucose-6-phosphate isomerase-induced arthritis (pGIA) and patients with RA. The team also went...

How the brain plays a role in rheumatoid arthritis inflammation

Source: Multiple Jul 21, 2018 6 years ago

In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain. A new study published in Nature Communications examines this issue. "Rheumatoid arthritis is an inflammatory and autoimmune condition with nasty levels of inflammation that can affect a person'...

Details of Systemic Lupus Erythematosus development uncovered

Source: Multiple Jul 20, 2018 6 years ago

Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation and tissue damage. SLE can involve many organs and systems and has a poor prognosis. It is one of a large group of autoimmune disorders, which occur when the immune system attacks the body's own tissues and organs. Type I interferon (IFN-I), a key protein that regulates the immune system's activity, i...

Using Edited Stem Cells To Fight Arthritis

Source: Multiple Jul 19, 2018 6 years ago

Goal is vaccine that targets inflammation in joints Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, idea...

Zydus Cadila gets nod for new Arthritis Drug.

Source: Zydus Cadila Jul 19, 2018 6 years ago

Zydus Cadila gets USFDA approval for arthritis drug,Piroxicam. Zydus Cadila has received final approval from the US health regulator for Piroxicam capsules, used for the treatment of osteoarthritis and rheumatoid arthritis. According to a BSE filing, Zydus Cadila will market Piroxicam Capsules USP in the strengths of 10 mg and 20 mg. The drug will be produced at the group’s manufa...

New gene therapy drug for rheumatoid arthritis undergoes phase 1 trial

Staff Writer, TMN Jul 09, 2018 6 years ago

Arthrogen, a biopharmaceutical company specializing in gene therapy, is now recruiting individuals with rheumatoid arthritis to test the new drug ART-I02. Khun Nantida does not wear clothes with buttons. Most of her pants have waistbands and do not require zipping. She uses only electric toothbrushes because she cannot brush her teeth as efficiently on her own. When Khun Nantida cooks for...

Novel Senolytic Osteoarthritis drug investigated

Staff Writer, TMN Jul 09, 2018 6 years ago

Currently, there is no cure for osteoarthritis, the most common joint problem in the United States. A new study brings hope of a single-injection fix. The drug on trial clears out old cells from the joints. Osteoarthritis (OA) is a type of arthritis that occurs when cartilage at the ends of bones wears down. It can affect any joint in the body, but it most commonly affects the hands, ne...

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COVID-19-News-Omicron-Hematuria-Proteinuria-Kidney-Damage
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Phenolic Phytochemicals From The Roselle Plant Or Hibiscus Sabdariffa (Thai: Krachiap กระเจี๊ยบ) Can Treat And Prevent Obesity

Herbs And Phytochemicals - Roselle - Obesity
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COVID-19 News - Head And Neck Cancers - By Nikhil P & Kittisak M
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Source: COVID-19 Supplements - Quercetin
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Source: COVID-19 Recovered Patients
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Source: Occulus Hirsutus and AQCH
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Source: High-Flow Nasal Cannula
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Source: Androgens And COVID-19
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Source: Nitric Oxide and COVID-19
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Source: COVID-19 Asymptomatic and Presymptomatic
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Source: SARS-CoV-2 Mutations
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