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Source: COVID-19 Research Jan 23, 2021 4 years ago
COVID-19 Research: A new study by researchers from the University of Illinois at Chicago shows that the nonstructural proteins of the SARS-CoV-2 coronavirus dysregulates the immune responses and cell signaling of the human host to generate a permissive environment.
According to the study team, the SARS-CoV-2 proteins upregulate or downregulate more than 100 human kinases involved in cellu...
Vaccine News: A new research by scientists from Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID)-University of Cambridge, University College London, University of Kent and Addenbrookes Hospital-UK shows that the Pfizer-BioNTech vaccine exhibits reduced neutralization potential against SARS-CoV-2 B.1.1.7 variant.
The new study findings contradicts Pfizer&rsqu...
Source: Viral Persistence Jan 22, 2021 4 years ago
Viral Persistence: A new research by scientists from the Georgia State University involving animal models has demonstrated that mice being infected with the SARS-Cov-2 coronavirus through their nasal passages developed severe illness due to brain infection even after the virus had left their lungs. The implications of the study findings suggest viral persistence in individuals despite testing nega...
Source: SARS-CoV-2 Variants Jan 22, 2021 4 years ago
SARS-CoV-2 Variants: Eachtime the SARS-CoV-2 coronavirus replicates, it has a chance to mutate. And given that it is currently rampaging around the world, it has plenty of opportunities to do just that.
Typically most of these mutations will make little or no difference to the virus's ability to spread or cause more severe disease. Others will make it less likely to spread ie those mu...
Research News: A new study by researchers from Washington University School of Medicine- St. Louis has found that individuals with Barrett’s Esophagus have increase susceptibility to COVID-19 disease.
Barrett’s esophagus is a condition in which the lining of the esophagus changes, becoming more like the lining of the small intestine rather than the esophagus. This occurs in th...
Source: SARS-CoV-2 origins Jan 21, 2021 4 years ago
Taiwan News staff writer Keoni Everington has written a piece with regards to a World Health Organization inspector being recorded on video discussing the testing of modified coronaviruses on human cells and humanized mice in the Wuhan Institute of Virology (WIV), just weeks before the first cases of COVID-19 were announced in the city of Wuhan itself.
Dr Vincent Racaniello (left) Dr Peter...
Source: SARS-CoV-2 Mutations Jan 21, 2021 4 years ago
SARS-CoV-2 Mutations: While certain vaccine manufacturers are releasing studies by their own staff claiming that their vaccines will still likely to work on the various emerging SARS-CoV-2 variants and many so called ‘credible’ American media are also publishing articles promoting this misinformation, South African researchers in a news study have confirmed that the 501Y.V2 variant esc...
N501Y Mutation: Scientist from University of Oxford in a news study have found that the N501Y mutation found on the SARS-CoV-2 B.1.17 variant possibly causes a higher viral load in those infected with the variant.
The B.1.1.7 variant also called VUI-202012/01 has emerged which is increasing in frequency, primarily in the South East of England
One potential hypothesis is that infect...
Source: Ivermectin-COVID-19 Jan 20, 2021 4 years ago
Ivermectin-COVID-19: While there are more than 50 studies currently expounding the efficacy of Ivermectin to treat COVID-19 and also as a prophylaxis against the COVID-19 disease, it usage should be carefully monitored and it should always be used under the supervision of a medical doctor or with proper dosing spelt out.
https://c19ivermectin.com/
The drug has yet to be officially approve...
Coronavirus News: As the SARS-CoV-2 continues to evolve and mutate to enhance its own survival despite therapeutic interventions such as convalescent plasma, monoclonal and combination monoclonal protocols, vaccines etc, more variants are fast emerging to counter all mankind’s initiatives and its imperative for researchers to identify all possible mutations that appear on the new variants th...
COVID-19 News: Scientist from the University of Southern California have discovered that the SARS-CoV-2 coronavirus typically ‘attacks’ the mitochondria in the cells of the human host. The resulting disruptions in the ‘power house’ of the cells could be one reason many COVID-19 patients and also post COVID patients often suffer from chronic fatigue.
In their study ab...
Source: SARS-CoV-2-Variant-News Jan 19, 2021 4 years ago
SARS-CoV-2 Variant News: A new lesser-known variant known as the L452R variant had been circulating in the Los Angeles county in the last few weeks according to Public Health Department.
The newly announced variant was first identified in Denmark in March 2020. It showed up in California as early as May.
Professor Dr Charles Chiu, a virologist and professor of laboratory medic...
Source: SARS-CoV-2 Variants Jan 18, 2021 4 years ago
SARS-CoV-2 Variants: A team from Southern Illinois University Carbondale traced the earliest appearance of new variant, called 20C-US, to Texas in May 2020. Scientists say the variant has not spread significantly beyond the country's borders, and that is most highly prevalent in the Upper Midwest.
However this third variant could be responsible for at lea...
COVID-19 News: Scientists from California based biotech company, Immunity Bio Inc have in a new study found that the combination Of E484K, K417N and N501Y mutations found in various new emerging SARS-CoV-2 variants can lead to immune evasion and reinfections even in those with previous immunity. The study findings also indicate that all the current COVID-19 vaccines would most probably be ine...
Coronavirus News: Chinese health authorities reported that active and infectious forms of the SARS-CoV-2 coronavirus were found on ice cream produced in the eastern city of Tianjin, prompting a recall of cartons from the same batch.
The ice cream manufacturer, Daqiaodao Food Co., Ltd. in Tianjin, adjacent to Beijing, was sealed and its employees were being tested for the SARS-CoV-2 corona...
COVID-19 News: Scientist are concerned over the new SARS-CoV-2 variant that emerged in Manaus, Brazil called P.1 that has more mutations on it than even the UK variant called B.1.1.7 or even the South African Variant called B.1.351 as it could change the course of the current pandemic if it starts becoming prevalent.
The new P.1 variant lineage carries 17 unique amino acid changes, 3 dele...
HIV News: A new international study led by the University of Southern California, involving various other research entities including University of Cape Town-South Africa,Thai Red Cross AIDS Research Centre-Thailand, University of Amsterdam-Netherlands, Washington University School of Medicine-USA, Missouri University of Novi Sad-Serbia ,University of New South Wales-Australia, University of Calif...
COVID-19 Drugs: Researchers from the University of Alabama at Birmingham have found in a new study that metformin usage among patients with type 2 diabetes had decreased mortality rates when contracting the COVID-19 disease.
The COVID-19 disease is a growing pandemic with an increasing death toll that has been linked to various comorbidities as well as racial disparity. However, the specific char...
Source: COVID-19 Research Jan 16, 2021 4 years ago
COVID-19 Research: Scientist from the University of Salento-Italy and the University of Paris-France in a new study have found that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the SARS-CoV-2 virus strain and that of the human host.
Variants of SARS-CoV-2 have been identified rapidly after the beginning of the COVID-19 pandemic. O...
Vaccine News: A new breaking development has emerged with a total of 23 deaths being reported by the Norwegian Medicines Agency in connection with the Pfizer’s /BioNTech vaccines. To date 13 of these cases have been assessed so far and confirmed as linked to the vaccines.
https://legemiddelverket.no/nyheter/meldte-bivirkninger-etter-koronavaksine-pr-14-januar-2021
Norway Reports 23 ...
Source: Coronavirus Latest Jan 15, 2021 4 years ago
Coronavirus Latest: Scientists from Brazil in a new study led by the University of Sao Paulo and involving numerous other research institutions have found that oxidative stress and neurotoxicity biomarkers increased in tadpoles exposed to synthetic SARS-CoV-2 spike protein peptides.
Aquatic animlas like prawns, not only tadpoles could be affected
by the SARS-CoV-2 coronavirus. Image Cr...
COVID-19 Drugs: A new study by researchers from University of Birmingham-UK, Keele University-UK, San Raffaele Scientific Institute-Italy, University of Copenhagen-Denmark and the University of Liverpool-UK demonstrates that the drug called Fenofibrate exhibits antiviral properties against the SARS-CoV- coronavirus and could be repurposed to treat COVID-19.
Fenofibrate, ...
COVID-19 News: Researchers from the Ohio State University Wexner Medical Center and College of Medicine have discovered a new variant of SARS-Cov-2, the virus that causes COVID-19 called the COH.20G/501Y variant.
The scientist are still in the process of deciphering all the various mutations found on the genome of this new variant but do admit that the new variant carries a...
Source: COVID-19 Research Jan 14, 2021 4 years ago
COVID-19 Research: Scientists from the Department of Molecular and Cell Biology, University of California-Berkeley have in a new study identified the SARS-CoV-2 ORF8 protein as being responsible for the rapidly evolving immune evasion characteristics of emerging strains and also responsible for the increasing pathogenicity of the coronavirus.
Crystal structure of SARS-CoV-2 ORF8. (A) A 2Fo-Fc el...
Vaccine News: At least three Democratic members of the House of Representatives despite having been vaccinated with the Pzifer/BioNtech vaccine were tested positive after the violent intrusion of Capitol by Trump supporters who were instigated to do so by the President himself! The three house representatives despite being masked themselves had to shelter for hours in tight proximity with Republic...
Post-COVID: A new study by researchers from Saint James's Hospital-Dublin and Trinity College-Dublin shows that even individuals who only experienced mild symptoms of COVID-19 initially upon infection, still continue to suffer a host of health complications even months after ‘recovery’.
Much is known about the acute infective process of SARS-CoV-2, the causative virus of t...
COVID-19 Latest: A new study by the Korea University led by microbiologist Heenam Stanley Kim Ph.D, from Division of Biosystems & Biomedical Sciences has found that individuals with poor gut health likely to develop severity when infected with the SARS-CoV-2 coronavirus.
COVID-19, which has been declared a pandemic, has exhibited a wide range of severity worldwide. Although this globa...
Source: B.1.1.248 Variant Jan 12, 2021 4 years ago
B.1.1.248 Variant: Japan health authorities have identified a new SARS-CoV-2 variant in travellers originating from Brazil.
Shockingly, the new variant called B.1.1.248 has 12 mutations on the spike protein alone!
Japan’s National Institute of Infectious Diseases on late Sunday said it had detected a new variant of the coronavirus in four travelers arriving from Brazil.
 ...
COVID-19 Herbs: Scientists from Columbia University in New York, the University of Washington, and Worcester Polytechnic Institute have demonstrated in a new vitro study that extracts from the herb Artemisia Annua inhibits the SARS-CoV-2 coronavirus replication, making it a possible therapeutic candidate for COVID-19.
Artemisia Annua Being Grown In Dok Kham Thai-Phayao, Thailand.
The curr...
Source: Ivermectin-COVID-19 Jan 12, 2021 4 years ago
Ivermectin-COVID-19: Indian researchers from the All India Institute of Medical Sciences have conducted a a double-blind, randomized, placebo-controlled clinical trial that demonstrated the efficacy of Ivermectin to treat COVID-19 disease. The clinical trial showed that Ivermectin, an anti-parasitic drug, can reduce in-hospital mortality rate COVID-19 patients.
Ivermectin is currently being used ...
Source: SARS-CoV-2 Research News Jan 11, 2021 4 years ago
SARS-CoV-2 Research News: A new study led by scientist from the University of Cambridge and also the National Institute of Allergy and Infectious Diseases at the National Institutes of Health along with researchers from the University of Sheffield have discovered that the SARS-CoV-2 coronavirus is capable of downregulating a critical human host protein called Tetherin which in turns enhances it sp...
Source: COVID-19 Mutations Jan 11, 2021 4 years ago
COVID-19 Mutations: Researchers the Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine- University of Hawaii have in a new study found that the P681H mutation emerging on sequencings of many globally prevalent SARS-CoV-2 strains.
This P681H mutation is immediately adjacent to the furin cleavage site, a known location of biological sig...
Vaccine News: Pfizer’s PR teams and the corrupted media they must have probably bought along with unethical medical experts are all helping to mislead the public that their vaccines are truly effective against the new variants including the B.1.1.7 strain.
Pfizer and BioNTech announced on Friday that their COVID-19 vaccine is effective against the emerging variants. https:...
Source: COVID-19 Diagnostics Jan 10, 2021 4 years ago
COVID-19 Diagnostics: The US FDA has issued official warnings about the potential risk for false negative results with PCR molecular tests for SARS-CoV-2 due to mutations such as a recently detected B.1.1.7 variant of the virus.
The US regulator issued an alert to clinical laboratory staff and clinicians. The agency warned that false negative results can occur with any molecular test for ...
COVID-19 Latest: Researchers from Brown University-Rhode Island, U.S., Yale University School of Medicine-U.S. and Kurume University School of Medicine-Japan have in a new study identified a human host enzyme called chitinase 3-like-1 (CHI3L1) as playing a critical role in the progression to disease severity of elderly COVID-19 patients.
COVID-19 is caused by the SARS-CoV-2 (SC2) coronavi...
Source: Thailand Medical News Jan 08, 2021 4 years ago
A new international study lead by medical researchers from Perelman School of Medicine at the University of Pennsylvania has found that common medications used to treat high blood pressure did not affect outcomes among patients hospitalized with COVID-19. This study findings provides relief to many as during the initial phases of the COVID-19 pandemic, there were speculations that certain blood pr...
COVID-19 News: Spanish researchers from the University of Valencia and INCLIVA Health Research Institute have discovered in a new study that Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses.
The study has recently investigated the durability of immune responses specifically developed against SARS-CoV-2, the causative pathogen of COVID-19. The study ...
Source: COVID-19 Warnings Jan 07, 2021 4 years ago
COVID-19 Warnings: According to a new study by researchers from the University of Bristol-UK and the University Hospitals Bristol and Weston NHS Foundation Trust, patients with acute heart failure nearly double their risk of dying if they get COVID-19.
In this single‐centre observational study, the study team examined referrals to the acute heart failure team over a period of 16 week...
Source: SARS-CoV-2 B.1.1.7 Variant Jan 07, 2021 4 years ago
SARS-CoV-2 B.1.1.7 Variant: British researchers warn that that existing non-pharmaceutical interventions (NPIs) may not be sufficient to contain the spread of the new SARS-CoV-2 B.1.1.7 variant that is fast becoming the prevailing dominant strain. The new variant has a higher binding affinity and is more infectious coupled with the fact that it has a higher replication rate.
Claims b...
Source: COVID-19 Quarantines Jan 07, 2021 4 years ago
COVID-19 Quarantines: The U.S. CDC has published a new warning that there is some onward transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from household contacts released from quarantine after seven or 10 days and that extra precautions still need to be adhered to.
The U.S. CDC warning was issued after a study was published in the Jan. 1 issue of the U.S. Cente...
Vaccine News: While the world is foolishly thinking that the COVID-19 vaccines are going to get things back to normal quickly, more concerning findings are emerging about the real efficacy of these vaccines that were basically initiated by the Trump administration (the same group that gave us scams like hydrocholoroquine, remdesivir, then Eli lily’s monoclonal antibodies and also Regeneron c...
COVID-19 News: Polish researchers from the University of Warsaw and the Polish Academy of Sciences are warning based on a new study that the new variant of the SARS-CoV-2 detected in England replicates more than two times faster than the earlier strains. This replication advantage enhances its capability to become to a dominant global variant in a matter of a short time.
The novel SARS‐Co...
Source: U.S. Medical News Jan 06, 2021 4 years ago
U.S. Medical News: It was reported that ambulances in Los Angeles and elsewhere in California are now stopping to transport some patients due to strain on hospitals as result of an exponential surge in COVID-19 cases.
In Los Angeles, ambulance workers have been told to stop transporting some patients with extremely low survival chances to hospital, and to limit oxygen use, as record COVID...
Source: COVID-19 Vaccine News: Jan 06, 2021 4 years ago
COVID-19 Vaccine News: About 9 hours ago, the Norwegian Medicines Agency announced that two inmates in a nursing home died few days after receiving a COVID-19 vaccine made by the American pharmaceutical company Pfizer and its German partner BioNTech that is owned by a Turkish muslim national, Uğur Şahin.
https://legemiddelverket.no/nyheter/dodsfall-hos-sykehjemsbeboere-etter-koronavaksinerin...
Source: COVID-19 Clinical Updates Jan 06, 2021 4 years ago
COVID-19 Clinical Updates: A new silico study by researchers from Massachusetts General Hospital (MGH) identifies the dynamics of the different COVID-19 phenotypes for optimizing clinical management and using better therapeutic strategies.
A unique feature of COVID-19 is its extreme heterogeneity ie illness ranges from minimally symptomatic to life threatening. This heterogeneity is a res...
Source: COVID-19 Research Jan 05, 2021 4 years ago
COVID-19 Research: Scientists from the University of Texas MD Anderson Cancer Center in Houston in a new detailed interactome study between the SARS-CoV-2 coronavirus and human host cells have identified 437 human proteins as high-confidence interacting proteins.
Host-virus protein-protein interaction is the key component of the SARS-CoV-2 lifecycle.
The study team conducted a comp...
UK COVID-19 News : The COVID-19 crisis in Britain is fast escalating and the UK healthcare system might witness a total collapse if things do not improve in the next few days. Already hospitals are overflowing and more than 58,000 new COVID-19 infections were reported in the last 24 hours along with 407 COVID-19 Deaths. To date, the United Kingdom has now climbed up to the fifth position in terms ...
Pharma News: Florida based AzurRx BioPharma, a company specializing in the development of non-systemic therapies for gastrointestinal (GI) diseases has announced that it has signed an exclusive worldwide licensing agreement with First Wave Bio, Inc for the use of their patented and proprietary oral and rectal formulations of niclosamide for the treatment of immune checkpoint inhibitor-as...
For those thinking 2020 was a bad year and that 2021 would be much better. Think again. Cast aside all these talks by clueless individuals saying that businesses and even tourism will bounce back this year. Be prepared for meltdowns in the financial and stock markets and in the worst scenario, there could even be a time when even currencies, gold and even bitcoins might not have any worth as compa...
Influenza News: A new study by researchers from University of Michigan School of Public Health-U.S., University of Washington School of Public Health-U.S., Jorma Gallen-Kallela Memorial Research Library-Finland and the Keck School of Medicine-University of Southern California-U.S. have found that cadmium is linked to more severe outcomes in influenza and pneumonia infections and also possibly even...
Source: COVID-19 Research Jan 03, 2021 4 years ago
COVID-19 Research: Indian scientists from the Rajiv Gandhi Centre for Biotechnology, Trivandrum, Kerala-INDIA along with researchers from Rutgers New Jersey Medical School-USA and Virginia Commonwealth University Medical Center-USA have in a recent computational study implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the SARS-CoV-2 coronavirus and opened the doo...
Vaccine News: Israeli’s Hadashot 13 TV News Channel has reported yesterday that more than 240 Israelis who had been earlier vaccinated with the Pfizer’s COVID-19 vaccine still tested positive for the COVID-19 disease.
The mass vaccination against COVID-19 began in Israel at the end of December, with Prime Minister Netanyahu and President Rivlin receiving the first doses o...
Source: SARS-CoV-2 Antibodies Jan 02, 2021 4 years ago
SARS-CoV-2 Antibodies: A study by scientists from the University of Oxford involving UK healthcare workers shows how antibody responses to SARS-CoV-2 infection can wane over time, depending on age, previous symptoms and ethnicity.
SARS-CoV-2 IgG antibody measurements can be used to estimate the proportion of a population exposed or infected and may be informative about the risk of future ...
Coronavirus News: A detailed autopsy study conducted by the U.S. National Institutes of Health has alarmingly uncovered hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples from COVID-19 patients who died shortly after contracting the disease.
However, the researchers saw no signs of SARS-CoV-2 in the tissue samples, suggesting the damage was not caused by a dir...
Source: COVID-19 Research Jan 02, 2021 4 years ago
COVID-19 Research: A new study published in the peer reviewed journal: Journal of Translational Autoimmunity indicates that pathogenic priming plays a part in COVID-19 disease severity and mortality via autoimmunity. https://www.sciencedirect.com/science/article/pii/S2589909020300186
Importantly homology between human and viral proteins is an established factor in viral- or vaccine-induce...