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COVID-19 Drugs: Canadian researchers from the University of Alberta are preparing to launch clinical trials of a drug called GC376 ( A prodrug of the parent drug called GC373) used to cure a deadly disease caused by a coronavirus in cats and they expect will also be effective as a treatment for humans against COVID-19 after successful vitro studies.
The study findings or the vitro trials ...
Acne Treatments: Acne has always been a nightmare for teenagers and also young adults for literally every decade and despite the vast amount of brands and product ranges of skin cares items; most often have to revert back to a dermatologist to get a dose of oral and topical antibiotics to get rid of the bacteria aggravating the condition. However, dermatologists do not have much of range of antibi...
Biotech News: MIT (Massachusetts Institute Of Technology) biotech engineers have developed a temporary film that could deliver drugs or aid in digestion and may help treat diabetes, infections, and other conditions.
Postdoctoral associate Junwei Li, lead author of the study, holds
an example of a capsule containing their enzyme.
Credit: Image by Melanie Gonick/MIT
Utilizing enzymes found in the...
Source: Nitric Oxide For COVID-19 Aug 27, 2020 4 years ago
Nitric Oxide For COVID-19: According to researchers from Massachusetts General Hospital (MGH), inhaled nitric oxide (NO) can be a valuable adjunct respiratory therapy for pregnant women with severe and critical COVID-19.
It was found that the delivery of the therapeutic gas to six COVID-19 pregnant patients admitted to MGH, resulted in a rapid and sustained improvement in cardiopulmonary function...
Source: Medical Innovations Aug 27, 2020 4 years ago
Medical Innovations: A new study by Japanese Conglomerate Panasonic in collaboration with Dr Mayo Yasugi, Associate Professor, Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University has verified and demonstrated the inhibitory effect of the hydroxyl radicals contained in water (nano-sized electrostatic atomized water particle) on...
Source: COVID-19 Antigen Test Aug 27, 2020 4 years ago
COVID-19 Antigen Test: The US FDA today announced that it has issued an emergency use authorization for the first antigen test where results can be read directly from the testing card, a similar design to some pregnancy tests.
This easy use but simple design test kits are fast and efficient for healthcare providers and patients and does not need the use of an analyzer.
Dr Jeff Shur...
Human Genes: A new international collaborative study shows that human host genes also play a role in the COVID-19 infections, symptoms and also progression of the disease. The study findings were published on a preprint server and have yet to have been peer-reviewed. https://www.medrxiv.org/content/10.1101/2020.08.21.20177246v1
COVID-19 causes a broad spectrum of symptoms from none at all...
Source: COVID-19 Disinfectants Aug 27, 2020 4 years ago
COVID-19 Disinfectants: A natural chemical compound called Citriodiol which is obtained from the essential oil of the lemon-scented gum consisting of citronellal from the eucalyptus citriodora tree had been found to be able to destroy the strain of coronavirus that causes the COVID-19 disease according to a preliminary study by Britain's defense laboratory.
https://assets.publishing....
Source: COVID-19 Clotting Aug 27, 2020 4 years ago
COVID-19 Clotting: It has been found that a major complication occurring in most critically ill COVID-19 patients is clotting in the lung's small blood vessels which leads to low oxygen levels in the body. Understanding why blood clots occur and how to treat them is key to treating severe cases of COVID-19.
A new study by researchers from Lawson Health Research Institute and Western Univers...
Source: COVID-19 Diagnostics Aug 27, 2020 4 years ago
COVID-19 Diagnostics: Researchers from Lawson Health Research Institute and Western University in a news study have identified six molecules that can be used as biomarkers to predict how severely ill a patient will become.
The research findings were published in the Journal: Critical Care Explorations, the official journal of the Society Of Critical Care Medicine https://journals.lww.com/...
Source: COVID-19 Treatments Aug 27, 2020 4 years ago
COVID-19 Treatments: Despite an early initiative by researchers from Mount Sinai School of Medicine to show that anticoagulation therapy was associated with improved survival among hospitalized COVID-19 patients, many questions remained such as the size of the potential benefit, and about what dosage of this therapy might be more effective.
A new observational study by the same the resear...
Source: Pancreatic Cancer Aug 26, 2020 4 years ago
Pancreatic Cancer: One of the most difficult cancers to treat and one that has a high mortality rate is pancreatic cancer. One of the reasons is for is that pancreatic cancer is rarely detected at its early stages because symptoms often do not present themselves until after the cancer has progressed. Very often by the time the cancer is detected, invasive procedures such as surgery, ch...
Source: Nutrition and Health Aug 26, 2020 4 years ago
Nutrition and Health: Medical researchers from the University of North Carolina recently published an analytical report in the British Medical Journal arguing for increased implementation of "food is medicine" interventions in the health care system.https://www.bmj.com/content/369/bmj.m2482
Dr Seth A. Berkowitz, MD, MPH, Assistant Professor of medicine at the University of N...
Medical News: Estradiol, the estrogen steroid hormone might confer a certain degree of protection to females claims a new study by European and American reseachers.
According to a new study by researcher from Universitätsmedizin Berlin-Germany, Sapienza University of Rome-Italy, Sant’Andrea University Hospital-Italy and University of Virginia-USA, it appears that wome...
Source: Coronavirus Treatments Aug 26, 2020 4 years ago
Coronavirus Treatments: Japanese researchers from Japan’s National Institute of Infectious Diseases are banking their hopes on an inhaled steroid called ciclesonide as the drug has both antiviral and also anti-inflammatory properties against the SARS-CoV-2 coronavirus.
In a recent study, the study team reports the in vitro suppression of both the MERS coronavirus and also the SARS-Cov-2 cor...
Source: COVID-19-Re-Infections Aug 26, 2020 4 years ago
COVID-19 Re-Infections: First it was the case of a 33 year old Hong Kong man who local scientist claim was the first case of a documented COVID-19 reinfection. The genetic tests revealed that a 33-year-old man returning to Hong Kong from a trip to Spain in mid-August had a different strain of the coronavirus than the one he'd previously been infected with in March, said Dr. Kelvin Kai-Wang To,...
Source: COVID-19 Treatments Aug 26, 2020 4 years ago
COVID-19 Treatments: A second clinical observation study, this time conducted by researchers from Harford hospital-Connecticut have demonstrated that administering famotidine to hospitalized COVID-19 patients was associated with a reduction in death and a composite endpoint of either death or intubation. The study involved 878 hospitalized COVID-19 patients of which 83 (9.5%) r...
COVID-19 Alerts: It was publicly announced that the US Food and Drug Administration (FDA) has revoked the umbrella emergency use authorization (EUA) it granted in May for intubation boxes once thought to keep healthcare providers safer when performing procedures on patients with COVID-19.
The US FDA specified in its announcement on Friday that the change applies to boxes th...
Source: COVID-19 Mutations Aug 26, 2020 4 years ago
COVID-19 Mutations: The SARS-CoV-2 since its debut in China in December 2019, is constantly evolving and mutating to ensure its survival. Unlike most viruses that upon series of mutations gradually losses its virulence and infectivity potential and sometimes simply ‘dies out, the SARS-CoV-2 coronavirus is evolving in a direction that seems to make it more stable and one of that it reasons it...
COVID-19 News: Despite a variety of neurological conditions being manifested in both COVID-1 patients and also in ‘recovered’ patients, such as headache, anosmia, ageusia, fatigue, confusion, seizure, and encephalopathy, scientist were not able to determine the way the virus was able to cross the brain barrier or ways it infected the central nervous system and there was no direct evide...
Influenza: A new large population-based study led by the US CDC and in collaboration with numerous institutions has shown that acute cardiovascular events, especially heart failure and ischemic heart disease, were found to be common among patients hospitalized with influenza.
The researchers suggest that vaccination is particularly important among those with cardiovascular risk factors.
&...
COVID-19 News: According to new research from the University of East Anglia-UK, medication for high blood pressure could improve COVID-19 survival rates and reduce the severity of infection.
The study team meta-analyzed data from a variety of sources involving more than 28,000 patients taking antihypertensives, a class of drugs that are used to treat hypertension also known as high blood ...
Source: Convalescent Plasma Aug 25, 2020 4 years ago
Convalescent Plasma: Commissioner of the US Food and Drug Administration, Dr Stephen Hahn, apologized on Monday after misrepresenting a key statistic on how effective blood plasma is for treating COVID-19 when announcing an emergency approval measure.
FDA Commissioner Stephen Hahn speaks as US President Donald Trump looks
on during a press conference at the White House on Sunday
The United Stat...
Source: COVID-19 Treatments Aug 25, 2020 4 years ago
COVID-19 Treatments: A new British study suggests that the use of antibiotics in individuals with COVID-19 could result in increased resistance to the drugs' benefits among the wider population.
The study findings were published in the Journal of Antimicrobial Chemotherapy. https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkaa338/5891793?searchresult=1
The study fou...
Source: Fructose Sweeteners Aug 25, 2020 4 years ago
Fructose Sweeteners: Contrary to previous fallacies, researchers from the University of California-San Diego School of Medicine report that fructose adversely affects the liver only after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut. The researchers say that developing treatments that prevent intestinal barri...
Source: Convalescent Plasma Aug 25, 2020 4 years ago
Convalescent Plasma: WHO or the World Health Organization yesterday warned that using blood plasma from COVID-19 survivors to treat other patients is still considered an experimental therapy, voicing the concern as a U.S. boost for the treatment has many scientists afraid formal studies will be derailed.
Shockingly on Sunday, the U.S. FDA authorized what's called "emergency use&q...
Coronavirus News: Initial scientific perceptions that interferons (IFNs) could help treat the COVID-19 disease are being challenged during the course of the last few months with a variety of emerging studies and it also leads us to question as to of many deaths could have been caused in the initial stages of the pandemic by doctors from China and elsewhere including in certain South-East Asian cou...
Coronavirus News: According to a new, global study led by researchers from the Zuckerberg Institute for Water Research at Ben-Gurion University of the Negev (BGU)-Israel, wastewater containing coronaviruses is more serious threat than ever imagined.
The research involves an international collaboration of 35 scientific researchers and evaluates recent studies on coronaviruses in wastewater...
Source: COVID-19 Antibodies Aug 25, 2020 4 years ago
COVID-19 Antibodies: Researchers from University of Massachusetts Medical School have discovered COVID specific IgA monoclonal antibodies that may provide effective immunity in the respiratory system against the SARS-CoV-2 coronavirus, a potentially much needed critical feature of an effective vaccine.
The research findings were published in the journal: Nature Communications. https://www...
Source: Erectile Dysfunction Aug 24, 2020 4 years ago
Erectile Dysfunction: A new meta-analysis study by researchers from Guangzhou Medical University, Guangdong-China has reported that the risk of erectile dysfunction in patients with gout was dramatically increased when compared with the general population, suggesting that clinicians should assess erectile function when treating an individual who suffers from gout.
The research findin...
Source: COVID-19 Immunology Aug 24, 2020 4 years ago
COVID-19 Immunology: Researchers from Karolinska Institutet-Sweden in a new study have discovered that so-called natural killer (NK) cells were strongly activated early after SARS-CoV-2 infection but that the type of activation differed in patients with moderate and severe COVID-19.
This new discovery brings researchers one step closer toward understanding how the immune system contribute...
COVID-19 Vaccine: A media release by Agence France-Presse(AFP) reports that a senior Catholic archbishop has warned he is "deeply troubled" by Australia's vaccine deal with AstraZeneca, saying the potential vaccine uses a fetal cell line that creates an "ethical quandary" for Christians.
This is the first time that Thailand Medical News is aware that fetal cell lin...
Source: Indonesia Coronavirus News Aug 24, 2020 4 years ago
Indonesia Coronavirus News: In a shocking official announcement, authorities announced that foreign tourists will not be allowed to visit Bali for the rest of 2020 due to coronavirus concerns.
Bali’s governor said that the local administration was scrapping a plan to open up the Indonesian island from next month.
The scenic holiday hotspot re-opened beaches, temples and other...
Source: New Zealand Coronavirus News Aug 24, 2020 4 years ago
New Zealand Coronavirus News: New Zealand’s Prime Minister Jacinda Ardern on Monday extended a lockdown in New Zealand's largest city, saying more time was needed to ensure a stubborn cluster of coronavirus infections was under control.
She also imposed mandatory mask wearing on public transport across the nation.
She said stay-at-home orders would remain in place across ...
Weight Loss: A new clinical trial study led by researchers from Oregon State University and included experts from Oregon Health & Science University and Boston University has demonstrated that alpha-lipoic acid given as a dietary supplement to overweight but otherwise healthy people was able to help many the patients in the study slim down.
The study findings are published in the ...
Source: U.S. Coronavirus News Aug 24, 2020 4 years ago
US Coronavirus News: In a shocking reversal of a planned stoppage of convalescent plasma treatments, the U.S. Food & Drug Administration (FDA) on late Sunday said it authorized the use of blood plasma from patients who have recovered from COVID-19 as a treatment for the disease, a day after President Donald Trump blamed the agency for impeding the rollout of coronavirus vaccines and therapeuti...
Source: COVID-19 Disinfectants Aug 24, 2020 4 years ago
COVID-19 Disinfectants: A Singaporean science journalist based in Massachusetts, XiaoZhi Lim recently raised concerns about the usage of disinfectants that contain “quats”-quaternary ammonium compounds which has been found to be toxic and has so far proven to cause developmental and fertility problems in mice and also disrupt various cellular pathways with serious implications for huma...
COVID-19 News: Netherlands based Hercules Pharmaceuticals, a biopharmaceutical company focusing on developing small molecule inhibitors of the Aryl Hydrocarbon Receptor (AhR) for treatment of cancer and viral infections, has announced the publication of promising preclinical in-vivo trial results, showing efficacy of its Aryl Hydrocarbon Receptor (AhR) inhibitor HP163 against Zika virus infection ...
COVID-19 Drugs: A randomized control trial of inhaled corticosteroids (ICS) on COPD patients led researchers to discover that inhaled corticosteroids could downregulate the expression of ACE2 receptors in the bronchial epithelial cells and also the epithelial cells in the airways. Furthermore the inhaled corticosteroids were found to also inhibit a human host protease gene ADAM17 that plays ...
Source: India Coronavirus News Aug 23, 2020 4 years ago
India Coronavirus News: In the last 24 hours, India health authorities have reported 69,239 new COVID-19 cases and 912 deaths; bringing the total number of infected cases in India to now 3,044,940.The total number of COVID-19 deaths in India now stands at 56,815. Once again Indian medical doctors and healthcare professionals are crying foul and saying that what is truly occurring at ground levels ...
COVID-19 Drugs: Remdesivir has so far emerged as another controversial drug that was approved by the US FDA under the Trump administration for emergency use despite the fact that it not clearly demonstrated its efficacy against the SARS-CoV-2 coronavirus nor was there any long term safety studies ever conducted on it use. It was granted approval merely on the basis that it shortened hospitalizatio...
COVID-19 Rehab: Eight Months down the COVID-19 pandemic, globally there has been more than 805,000 deaths officially reported or an average of one death every 20 seconds. Officially there has been about 23.5 million people globally infected but the real realistic figure could come close to about 310 million people (or about 18 people getting infected every second). Contrary to lies or misinformati...
HIV News: The trend for HIV drug research is now shifting towards drugs with long lasting effects without the need for HIV patients to adhere to stringent daily regimens and doses which can be quiet stressful at times.
Scientists from the University of Utah Health in collaboration with researchers from the National Institute of Allergy and Infectious Diseases (NIAID), Beth Israel Deacones...
Source: Cardiovascular Disease Aug 23, 2020 4 years ago
Cardiovascular Disease: A new study led by Australian researchers from Edith Cowan University, University of Western Australia, Flinders University, University of Sydney and also American researchers from Harvard Medical School, University of Minnesota and HealthPartners Institute-Minneapolis shows that cruciferous vegetables could be the most beneficial when it comes to preventing advanced blood ...
Source: COVID-19 Research Aug 23, 2020 4 years ago
COVID-19 Research: A new bioinformatics study by researchers from University of Pennsylvania and Shanghai University studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics have uncovered that cytokine-cytokine receptor interactions, P53 signaling pathways, and apoptosis are the main...
COVID-19 Herbs: Various computational molecular docking studies have shown that phytochemicals present in green tea or Camellia sinensis has the potential to inhibit the SARS-CoV-2 coronavirus.
https://www.sciencedirect.com/science/article/pii/S0944711320301185?via%3Dihub
https://www.tandfonline.com/doi/full/10.1080/07391102.2020.1779818
https://www.researchsquare.com/article/rs-19...
COVID-19 Vaccine: Researchers from Washington University School of Medicine-St. Louis have developed a vaccine that targets the SARS-CoV-2 coronavirus and can be administered through the nose in one dose.
Studies in mice models susceptible to the SARS-CoV-2 coronavirus have proven to be effective in preventing infection.
The study team next plans to test the vaccine in nonhuman pri...
COVID-19 Rehab: Numerous studies have already demonstrated that COVID-19 also damages the heart, ie damage either caused by the SARS-CoV-2 coronavirus itself, or from inflammation triggered by the immune system's response to the virus or from increased clotting in heart vessels.
However there is now emerging evidence that heart damage may persist even after the patient recovers and, i...
Source: U.S. Medical News Aug 22, 2020 4 years ago
U.S. Medical News: In what is shocking the medical community not only in America but also internationally, the white house has issued a new policy order midweek that removed all regulatory powers from the US FDA with regards to regulating and standardizing all medical laboratory test.
The new order which even stunned the US FDA, shocked health experts and laboratories because of its timin...
COVID-19 News: A new international genomic study led by researchers from the University of California-Davis alarmingly indicates that humans are not the only species facing a potential threat from SARS-CoV-2. The study team discovered that many of the 410 different species of vertebrates included in the study comprising birds, fish, amphibians, reptiles and mammals were vulnerable due to the prese...
Source: COVID-19 Mutations Aug 22, 2020 4 years ago
SARS-CoV-2 Mutations: A new machine learning model incorporating a new generation of artificial intelligence (AI), developed by researchers at Michigan State University indicate that mutations to the SARS-CoV-2 genome have made the virus more infectious.
The machine learning model, developed by lead researcher Dr Guowei Wei, Professor in the departments of Mathematics and Biochemistry and ...
Source: COVID-19 Immunology Aug 21, 2020 4 years ago
COVID-19 Immunology: Australian scientist from Monash University, the University of Melbourne and James Cook University have made a disturbing discovery that infection with the SARS-CoV-2 coronavirus might compromise the activation of the CD8+ T-cell responses that would usually ameliorate disease and drive recovery.
The research findings are published on a preprint server...
Source: Europe Covid-19 News Aug 21, 2020 4 years ago
Europe Covid-19 News: Europe is basically reverting back to the early days of the pandemic as new cases of COVID-19 infections are reaching record highs again.
Reports are showing that the pandemic was rebounding across the continent, often due to travel, summer holidays and parties plus youths and younger adults are adopting a carefree attitude and disregarding social distancing measures...
Source: COVID-19 Genomics Aug 21, 2020 4 years ago
COVID-19 Genomics: Researchers from Sanford Burnham Prebys Medical Discovery Institute and the University of California-San Francisco have discovered that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host. These proteins are also most probably responsible fo...
Source: COVID-19 Vaccines Aug 21, 2020 4 years ago
COVID-19 Vaccines: Pfizer Inc. and BioNTech has released additional Phase 1 safety and immunogenicity data from their ongoing U.S. study of the BNT162 mRNA-based vaccine program against SARS-CoV-2, which has advanced into Phase 2/3 evaluation.
The clinical data is published on a preprint server and is pending peer-review. https://www.medrxiv.org/content/10.1101/2020.08...