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Source: COVID-19 Case Study  Jul 07, 2020  4 years ago
COVID-19 Case Study: Numerous patients with severe COVID-19 remain unresponsive after surviving critical illness. Medical Researchers from Massachusetts General Hospital (MGH) presents  a case in which a patient with severe COVID-19 who, despite prolonged unresponsiveness and structural brain abnormalities, demonstrated functionally intact brain connections when functional MRI was used and we...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: In a new study by researchers from US NIH, Columbia University and John Hopkins University, it has been shown that the SARS-CoV-2 coronavirus is proving itself to be an elusive foe, evading immune surveillance while instigating hyper-inflammatory responses that eventually destroy the host in a significant minority of cases. The study reports the role of pH in helping the virus e...
Source: COVID-19 Vaccine News  Jul 07, 2020  4 years ago
COVID-19 Vaccine News: Biotech manufacturing company-Emergent BioSolutions, based in Maryland, entered a five-year manufacturing services deal with Janssen Pharmaceutical, a Johnson & Johnson company, to manufacture J&J’s Ad26.COV2-S COVID-19 vaccine. Emergent will handle contract development and manufacturing (CDMO) services in a deal that is valued at ...
Source: COVID-19 Antibodies  Jul 07, 2020  4 years ago
COVID-19 Antibodies: New York based Regeneron Pharmaceuticals announced its double-antibody cocktail against COVID-19 is advancing into Phase III studies, less than a month after the start of its first clinical trial, with preliminary data from one study expected to be reported later this summer. Regeneron's Biotech Plant   The biotech company said it is proceeding with clinical develop...
Source: COVID-19 Medical Devices  Jul 07, 2020  4 years ago
COVID-19 Medical Devices: To date, emerging studies suggests that COVID-19 patients are at a higher risk of stroke and promptly diagnosing and treating such patients is a priority in hospitals across the world.   Furthermore, identifying which COVID-19 patients are at increased risk of developing a stroke is also important, and may help with preemptive treatment and monitoring.   Los A...
Source: COVID-19 Vaccine Updates  Jul 07, 2020  4 years ago
COVID-19 Vaccine Updates: It was announced that vaccine candidate COVAX-19 developed by Vaxine Pty Ltd and Flinders University will commence Phase 1 trials at the Royal Adelaide Hospital (RAH) to test its efficacy.   The phase I trial will provide initial safety and immune response data on 40 healthy participants aged between 18 and 65 years who have already been pre-screened.   Resear...
Source: COVID-19 Drugs  Jul 07, 2020  4 years ago
COVID-19 Drugs: Researchers from University of South Florida Health (USF Health) Morsani College of Medicine scientists along with pharmaceutical experts from the University of Arizona College of Pharmacy have identified several existing drug compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The identified inhibitors all demon...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: A new study by  Dr Anna Aksenova, a senior research associate at the Laboratory of Amyloid Biology at St Petersburg University, has advanced a hypothesis that the severe course of COVID-19 may be associated with the von Willebrand factor, a blood glycoprotein that is one of the main components of the blood coagulation system.   The research findings have been peer re...
Source: COVID-19 Research  Jul 07, 2020  4 years ago
COVID-19 Research: A research in which US Military bioweapon researchers tested the stability of the SARS-CoV-2 pathogen on various surfaces, including paper currency and pig skin showed that the novel coronavirus can live for days on animal skin at room temperature and even up to 2 weeks on refrigerated pig skin.   The study has huge implications in the food industry, meat processing plant...
Source : Masks  Jul 06, 2020  4 years ago
We apologize to readers first for posting such an article on our site but we simply just could not resist the kind of stupidity materializing from the COVID-19 pandemic! While many Americans and Europeans are refusing to wear protective mask against the SARS-V-2 coronavirus either due to political reasons or sheer stupidity, across the globe in India, we have the protective mask evolving into a f...
Source: Bubonic Plague China  Jul 06, 2020  4 years ago
Bubonic Plague: China health authorities have reported an outbreak of Bubonic Plague in the inner Mongolia Autonomous Region.   Bubonic plague, caused by bacterial infection, was responsible for one of the deadliest epidemics in human history  ie the Black Death which killed about 50 million people across Africa, Asia and Europe in the 14th Century.   There have been a handful of ...
Source: COVID-19 Genomics  Jul 06, 2020  4 years ago
GOVID-19 Genomics: A major genetic risk variant found on the SARs-CoV-2 coronavirus RNA which comprises of a stretch of six genes that seems to increase the risk of severe illness from the coronavirus was found to be part of a stretch of DNA passed down from Neanderthals 60,000 years ago, according to a new study by genomic experts from the Max Planck Institute for Evolutionary Anthropology-German...
Source: COVID-19 Vaccine  Jul 06, 2020  4 years ago
COVID-19 Vaccine:  Professor of vaccinology at the University of Oxford, and one of the scientists leading the vaccine initiative, Dr Sarah Gilbert, told the U.K.'s Science and Technology Committee last week that their candidate vaccine has progressed to the phase III trial in the United Kingdom.   Phase III trials typically involves tens of thousands of research participants acros...
Source: Flu Vaccine  Jul 06, 2020  4 years ago
Flu Vaccine: Researchers from the Swiss Tropical and Public Health Institute, the University of Basel and University of Sao Paulo Medical School in a new research involving over 92,000 patients with COVID-19 in Brazil shows that the risks of severe disease, ventilatory support requirement, and death are reduced with a recent trivalent influenza vaccine. The research findings were printed on a pre...
Source: COVID-19 Diagnostics  Jul 06, 2020  4 years ago
COVID-19 Diagnostics: A new research from the University of Virginia (UVA) School of Medicine suggests doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator. The main biomarker that should be looked out for is the cytokine IL-13 (Interleukin 13). High levels of IL-13 were associated with worsened...
Source: Generic Remdesivir  Jul 06, 2020  4 years ago
Generic Remdesivir: The Trump administration last week proudly announced that it had secured 500,000 doses of Gilead’s remdesivir at prices that were set by Gilead at between US$2,340 to US$3,120. https://www.thailandmedical.news/news/breaking-remdesivir-gilead-sets-price-at-us$2,340-to-us$3,120-for-drug-that-has-no-safety-studies-or-true-efficacy-except-that-it-shortens-hospitaliza  ...
Source: SARS-CoV-2 Is Airborne  Jul 06, 2020  4 years ago
WHO: Despite mounting evidence that the SARS-CoV-2 coronavirus is airborne and that the general public worldwide needs to be aware of this, the WHO (World Health Organization) is still taking a stance that it is not the case but is only spread by large respiratory droplets that, once expelled by infected people in coughs and sneezes, fall quickly to the floor.   The  WHO lead by black ...
Source: COVID-19 Diagnostics  Jul 05, 2020  4 years ago
COVID-19 Diagnostics: The US FDA last week  on  granted Emergency Use Authorization to a new molecular diagnostic test from the US Centers for Disease Control and Prevention that can detect and differentiate the viruses that cause COVID-19 and flu.   The new Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time RT-PCR test intended for the simultaneous detection and differ...
Source: COVID-19 Innovations  Jul 05, 2020  4 years ago
COVID-19 Innovations: The current COVID-19 pandemic has brought a slew of new challenges for clinical facilities, including how to deliver as much care as possible at a distance or remotely not only for precautionary measures to safeguard the wellbeing of healthcare staff but only for better monitoring of COVID-19 patients..   Researchers from the Department of Cardiovascular Medicine at To...
Source: Autoimmunity  Jul 05, 2020  4 years ago
Autoimmunity: In normal roles, the immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially resulting in autoimmune diseases.   Researchers from Osaka University In a new study have discovered how reversible modifications to DNA by certain proteins protect from autoimmune diseases, and conversely, how the absence of these ...
Source: COVID-19 And HIV  Jul 05, 2020  4 years ago
COVID-19 And HIV: Individuals with HIV who were hospitalized with COVID-19 did not have worse results than COVID-19 patients without HIV, according to new research by Icahn School of Medicine at Mount Sinai.   The research findings were published in the journal: Clinical Infectious Diseases https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa880/5864410?searchresult=1   Study...
Source:  Jul 05, 2020  4 years ago
COVID-19 Pharma News: Pharma giant Merck, a leading science and technology company, announced that the US FDA has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. Merck will initiate a Phase II randomized, controlled clinical study evaluating the safety and efficacy of M5049 in this patient population. M5049 is a potentially fi...
Source: Melatonin and COVID-19  Jul 05, 2020  4 years ago
Melatonin and COVID-19: Another study by researchers from Peking Union Medical College in China and the University of Texas- San Antonio in America have in a new peer-reviewed finding that is published in the journal: Life Sciences By Science Direct, propose that Melatonin should be incorporated as an adjuvant treatment for COVID-19 as it has proven mechanisms to target Inflammasomes that triggers...
Source: COVID-19 Vaccine  Jul 05, 2020  4 years ago
COVID-19 Vaccine: Researchers from China have created an artificial protein that they say could be the basis of a vaccine to help ward off various deadly coronaviruses, including the pathogen that causes Covid-19 Copyright: Credit: Xinhua    The researchers from the Chinese CDC said the approach triggered a strong antibody response in mice and monkey trials to Middle Eas...
Source: COVID-19 Clinical Care  Jul 04, 2020  4 years ago
COVID-19 Clinical Care: Researchers are expressing that more safety data is needed in terms of treatment of symptomatic COVID-19 patients on antivirals with anticancer drugs.   A report published in the European Journal of Cancer by a group of French investigators led by Dr Paul Gougis of the Department of pharmacology, Hôpital Pitié-Salpêtrière in Paris, Franc...
Source: COVID-19 Drugs  Jul 04, 2020  4 years ago
COVID-19 Drugs: EUSA Pharma has secured approval from the U.S. Food & Drug Administration (FDA) for a Phase III clinical trial protocol of intravenous siltuximab plus standard of care in hospitalized patients with Covid-19 associated Acute Respiratory Distress Syndrome (ARDS). The pharmaceutical company will now proceed with the randomized, double-blind, placebo-controlled clinical trial to e...
Source: COVID-19 Vaccine  Jul 04, 2020  4 years ago
COVID-19 Vaccine:  Indian pharmaceutical company, Zydus Cadila received the green signal from the Drug Controller General of India (DGCI) to start phase I and II of their clinical trials on human participants. Over 120 independent scientific bodies are in contention to find a potential COVID-19 vaccine. Over 7 vaccines are being researched in India and just this week, two candidate groups ...
Source: Thailand Medical News  Jul 04, 2020  4 years ago
The human brain has a high energy demand and reacts very sensitively to oxygen deficiency. Ludwig Maximilian University of Munich neurobiologists have now succeeded for the first time in directly correlating oxygen consumption with the activity of certain nerve cells.   Typically, the brain requires a disproportionate amount of energy compared to its body mass. This energy is mainly generat...
Source: HIV Drugs  Jul 04, 2020  4 years ago
HIV Drugs: The drug Rukobia (fostemsavir) has been approved by The U.S. FDA for adults living with HIV who have tried multiple HIV medications and whose HIV infection cannot be successfully treated with other therapies because of resistance, intolerance or safety considerations. Rukobia (Fostemsavir) is a new type of antiretroviral medication to be taken twice daily by mouth. It is a prodrug, whi...
Source: COVID-19 Vaccine Updates  Jul 04, 2020  4 years ago
COVID-19 Vaccine Updates:  Pharmaceutical and Biotech giants, Pfizer and BioNTech reported that the most advanced of four constructs of their messenger RNA (mRNA) vaccine candidate for COVID-19 showed encouraging immunogenicity and a favorable safety profile in preliminary Phase I/II data published in a preprint study. https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1   Bot...
Source: COVID-19 Disinfectants  Jul 04, 2020  4 years ago
COVID-19 Disinfectants:  University of Manchester scientists say that a little-known non-toxic antiseptic developed in the Soviet Union during the Cold War has enormous potential to beat common infections and that even detailed studies should be conducted with regards to its use in the current COVID-19 scenario. Their report was published in the journal: FEMS Microbiology Reviews. https://aca...
Source: Chronic Fatigue Syndrome  Jul 04, 2020  4 years ago
Chronic Fatigue Syndrome: There has been so many clinical manifestation of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) reported in COVID-19 patients experiencing mild to moderate symptoms and also in typically asymptomatic and also recovered COVID-19 patients. To date medical experts do not have a proper explanation for this.   However, browsing through various new COVI...
Source: COVID-19 Research  Jul 04, 2020  4 years ago
COVID-19 Research: Researchers from the University Of Bristol in a new review published in the Journal Of Infection indicate that liver complications are common and are associated with more severe disease in patients with COVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306105/ or https://www.journalofinfection.com/article/S0163-4453(20)30425-4/pdf   Dr Setor K. Kunutsor of Bristol M...
Source: COVID-19 Pediatrics  Jul 04, 2020  4 years ago
COVID-19 Pediatrics: Researchers from the University College London Institute of Neurology are warning that children with COVID-19 may present with new neurological symptoms involving the central and peripheral nervous systems, and splenial changes on imaging.   The new research findings were published the journal: JAMA Neurology. https://jamanetwork.com/journals/jamaneurology/fullarticle/2...
Source: COVID-19 Drugs  Jul 03, 2020  4 years ago
COVID-19 Drugs and Erythropoietin: German researchers from the Max Planck Institute of Experimental Medicine in Göttingen suggest that the anemia drug Erythropoietin (Epo) which is sometimes misused as doping agent could also be effective against COVID-19. EPO, the growth factor could also mitigate severe disease progression and protect patients from long-term neurological effects when the ...
Source: SARS-COV-2 Mutations  Jul 03, 2020  4 years ago
SARS-COV-2 Mutations: Virologists and genomic researchers now know that two major variants of the novel coronavirus (SARS-CoV-2) are circulating in the United States and elsewhere at the moment besides the hundreds of minor variants. The variants, called G614 and D614, have just a small difference in their "spike" protein, the viral machinery that coronaviruses use to enter hos...
Source: U.S. COVID-19 News  Jul 03, 2020  4 years ago
U.S. COVID-19 News: America sets a new record in the last 24 hours with 53,069 (Thursday) new coronavirus infections in the last 24 hours. The country now has recorded a total of 2,837,189 COVID-19 Infections of which health authorities claim that 1,191,102 have ‘recovered.’ A total of 131,217 Americans have died from the COVID-19.   What is even scarier is that it is reported t...
Source: COVID-19 Diagnostics  Jul 03, 2020  4 years ago
COVID-19 Diagnostics: Despite the fact  that accurate and widespread testing is crucial to managing the coronavirus pandemic, many individuals in the U.S. and even elsewhere globally still can’t get tested for COVID-19 without visiting designated sites. A rendering of a potential affordable, handheld COVID-19 testing device. The researchers hope to be evaluating prototyp...
Source: COVID-19 Drugs  Jul 03, 2020  4 years ago
COVID-19 Drugs: Researchers from the University of North Carolina (UNC) have used a new web-based platform to help identify synergistic and antagonistic drug combinations and their underlying mechanisms of action in the context of fighting the SARS-CoV-2 coronavirus disease.   The data mining tool, called COVID-KOP, prioritized 73 combinations of 32 drugs as potential treatments for COVID-1...
Source: COVID-19 and Strokes  Jul 03, 2020  4 years ago
COVID-19 and Strokes: A new study finds that although both Influenza and COVID-19 can raise the risk for a stroke, the odds appear to be eight times higher with the SARS-CoV-2 coronavirus.   The researchers found that among more than 1,900 patients with COVID-19, 1.6% suffered a stroke, versus 0.2% of nearly 1,500 patients seriously ill with flu.   The research findings ...
Source: COVID-19 Hypoxia  Jul 03, 2020  4 years ago
COVID-19 Hypoxia:  Researchers from Hines Veterans Affairs Hospital and Loyola University of Chicago in a new study provides possible explanations for COVID-19 patients who present with extremely low, otherwise life-threatening levels of oxygen, but no signs of dyspnea (difficulty breathing). This new understanding of the condition, known as silent hypoxemia or 'happy hypoxia,' could ...
Source: COVID-19 and the Endocrine System  Jul 02, 2020  4 years ago
COVID-19 Endocrine System: It seems that the damage from the SARS-CoV-2 coronavirus is never ending. Starting out initially as a respiratory disease that causes damage to the lungs, studies progressed to show that it also affects the immunity system, the gastroenterological system, the clotting mechanisms, the neurological system, the heart and circulatory system, the reproductive system in males ...
Source: HIV and Lenacapavir  Jul 02, 2020  4 years ago
HIV and Lenacapavir: Gilead scientists are reporting an early step toward an HIV drug that could potentially be taken only a couple of times per year.   A new study showed that a single injection of the experimental drug, called lenacapavir, was able to lower blood levels of HIV in a small group of patients. And it was capable of maintaining active levels in the blood for more than six...
Source: Skin Inflammation  Jul 02, 2020  4 years ago
Skin Inflammation: Researchers from Ohio State University Wexner Medical Center have demonstrated in animal models using mice that diets rich in black raspberries can reduce inflammation associated with skin allergies.   The research findings were published in the journal: Nutrients https://www.mdpi.com/2072-6643/12/6/1701   The study showed that black raspberries reduced inf...
Source: Antibiotics and Microbiome  Jul 02, 2020  4 years ago
Antibiotics: Researchers from the University Of Melbourne and Baylor College of Medicine-Texas have found in a new study that antibiotic exposure during crucial developmental periods in early childhood alters digestive tract nerve function and bacterial colonies.   The research finds are published in the American Journal of Physiology-Gastrointestinal and Liver Physiology. https://jour...
Source: COVID-19 Recovered Patients  Jul 02, 2020  4 years ago
COVID-19 Recovered Patients: A collaborative study in China involving leading universities and hospitals headed by Wuhan Institute Of Virology has discovered that recovered patients who even after 2 to 11 weeks of being discharged from hospitals, displayed a remarkable phenotypic alterations in lymphocytes after clinical recovery. This suggests SARS-CoV-2 infection imprints profoundly on lymphocyt...
Source: Diabetes and COVID-19  Jul 02, 2020  4 years ago
Diabetes And COVID-19: A case study by German researchers from University of Kiel have confirmed that the Sars-CoV-2 coronavirus can trigger diabetes and insulin dependency in young adults who have otherwise been healthy with any prior history of sickness or diabetes. It is assumed that the diabetes is triggered by the SARS-CoV-2 coronavirus attacking the pancreas thru the ACE-2 receptors present ...
Source: COVID-19 Diagnostics  Jul 02, 2020  4 years ago
COVID-19 Diagnostics:  Researchers from the Innovative Genomics Institute (IGI), the same UC Berkeley group that rapidly popped up a state-of-the-art COVID-19 testing laboratory in March, are now trialing a quicker way to obtain patient samples: through saliva. So far diagnostic tests for COVID-19 have relied on samples obtained by swabbing uncomfortably deep into a person’s nasal pa...
Source: US Medical News  Jul 02, 2020  4 years ago
US Medical News: Daily new COVID-19 cases in America soared past 51,097 in the last 24 hours for the first time, as the World Health Organization delivered a grave warning that the global pandemic is accelerating.   Clubs, restaurants, bars and beaches in the world's worst-hit nation closed from California to Florida, as states reeling from yet another surge in the deadly virus&nbs...
Source: COVID-19 Latest  Jul 02, 2020  4 years ago
COVID-19 Latest: Researchers from Utrecht University, UMC Utrecht, and Erasmus MC have discovered that platelets also play a role in the immune system: They appear to be indispensable in protecting the respiratory system against pathogens despite their primary role in blood coagulation and the development of thrombosis.   Lead researcher Dr Erhard van der Vries told Thailand Medical News, &...
Source: COVID-19 Vaccine  Jul 02, 2020  4 years ago
COVID-19 Vaccine:  Members of the National Institutes of Health's Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development.   In a new report published in th...
Source: COVID-19 Drugs and Fostamatinib  Jul 02, 2020  4 years ago
COVID-19 Drugs: Fostamatinib, an FDA-approved monoclonal antibody that is a spleen tyrosine kinase inhibitor (SYK), was studied by researchers from Harvards’ Broad Institute, Imperial College’s Hammersmith Hospital, Brigham and Women’s Hospital and Harvard Medical School for possible use to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respi...
Source: COVID-19 Endotheliopathy  Jul 02, 2020  4 years ago
COVID-19 Endotheliopathy:  Yale University researchers have found that injury to endothelial cells ie the cells lining blood vessels may be a key driver of COVID-19 severity and death. The new research may help to explain the mysterious blood clotting seen in some patients with COVID-19, a condition associated with the most severe cases and death. The discovery suggests that doctors could ...
Source: COVID-19 Antibodies  Jul 02, 2020  4 years ago
COVID-19 Antibodies: A new research published by the British Medical Journal, (BMJ) yesterday highlights major weaknesses that exist in the evidence base for COVID-19 antibody tests. https://www.bmj.com/content/370/bmj.m2516   The research found that the evidence is particularly weak for point-of-care tests (performed directly with a patient, outside of a laboratory) and does not support...
Source: World Covid-19 News  Jul 01, 2020  4 years ago
World Covid-19 News: The world has recorded 10,614,957 official COVID-19 infections and 514,635 deaths in the last six months as of Ist July 2020 (5am California). The actual figures are at least 5 fold for both infection and deaths due to underreporting and concealments by many countries. Unfortunately despite the relative high figures, people are still complacent and many are living in denial. (...

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