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Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States.
Reporting last month in the journal Cellular and Molecular Gastroenterology and Hepatology, Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4.
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Dr. Zui Pan. Credit: University of Texas at Arlington
Researchers at the University of Texas at Arlington's College of Nursing and Health Innovation have developed a new nanoparticle-based platform for simultaneous imaging and treatment of esophageal cancer.
Together with colleagues from The Ohio State University, researchers manufactured polypeptide nanoparticles, which have ne...
Results from two clinical trials are expected to improve the outlook for people diagnosed with early-stage pancreatic cancer that can be treated with surgery.
In the first trial, changing the type of chemotherapy given after surgery from a single drug to a multi-drug regimen greatly improved how long patients lived. Patients in the trial treated with the multi-drug regimen survived for an ...
Treatment wakes up dormant tumour cells which can allow cancer to come back after chemotherapy before slamming on an irreversible ‘stop’ button
A medication more commonly used to treat fungal toenail infections may be helpful in fighting off persistent colorectal cancers which kill 4,000 people in the Thailand each year, a new study has found.
Colore...
The Provincial Health Office of Roi Et, Thailand, received the 2018 UN Public Service Award for its cervical cancer prevention programme and promoting gender responsive public services.
Just two decades ago, cervical cancer was the most common cancer for women in Thailand and the country struggled to provide the standard cytology and referral approach due to lack of infrastructure, acce...
MIT researchers discovered and patented magnesium L-threonate based on its unique ability to boost brain levels of magnesium.
Rapid absorption and ability to enter the brain enables this magnesium to structurally reverse certain aspects of brain aging.1-4
A recent human study demonstrates the benefits of magnesium L...
Currently, there is no cure for osteoarthritis, the most common joint problem in the United States. A new study brings hope of a single-injection fix. The drug on trial clears out old cells from the joints.
Osteoarthritis (OA) is a type of arthritis that occurs when cartilage at the ends of bones wears down. It can affect any joint in the body, but it most commonly affects the hands, ne...
Obstructive sleep apnoea has been linked to brain changes seen in the early stages of dementia, University of Sydney research reveals.
Published today in The European Respiratory Journal, the study's authors say the finding provides evidence that screening older people for obstructive sleep apnoea (OSA) and providing treatment where needed could help prevent dementia in this po...
A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a study.
Researchers at the University of Central Florida (UCF) in the US have discovered a link between rheumatoid arthritis and Mycobacterium avium subspecies paratuberculosis, known as MAP, a bacteria found in about half the cows i...
Biogen announced surprise successful results from an Alzheimer's drug clinical trial that sent shares of the pharmaceutical company soaring.
Alzheimer's drug research has been plagued by years of unrelenting failures, leading companies including Pfizer to give up the search for new compounds.
Dementia experts have questioned the narrow focus from biotech companies on amyloid ...
Some researchers believe they will soon be able to slow or even stop the body's clock—at least for a little while
The majority of older people live out their final years with at least one or two chronic ailments, such as arthritis, diabetes, heart disease or stroke. The longer their body clock ticks, the more disabling conditions they face. Doctors and drug companies traditionally...
Cryo-electron microscopy images reveal details of protein, RNA binding and possible drug-target sites
Shown is the space-filling model of human telomerase holoenzyme structure determined by cryo-electron microscopy (cryo-EM). Telomerase catalyzes the synthesis of telomeric DNA (green) at the ends of chromosomes (blue) to compensate for the loss of telomeres during genome replication. The structu...
Experts on the forefront of anti-aging medicine say the field is booming, with therapies on the horizon to target illnesses like cancer and Alzheimer's and make for a healthier, older population in the years to come.
Such remedies are increasingly important because of the world's aging population. Growing old, experts say, is a leading risk factor for most human diseases and a majo...
Men and women are now opting for hand injections in an effort to turn back time and reverse telltale signs of ageing.
For many, hands can be a sign of someone's age - as they are often the first body part to show protruding veins and tendons, lack of skin elasticity, and sunspots.
Now, in response to a growing number of people who'll do whatever they can to stay looking ...
The MALDI TOS Spectrometer
In a recent article published in the Siriraj Medical Journal, a team at the Department of Microbiology. Siriraj Hospital, had developed a new method of identifying rare pathogenic bacteria using the Maldi Tos Mass Spectrometry Method. (MALDI is the abbreviation for Matrix Assisted Laser Desorption/Ionisation, while TOS is the abbreviation for Time of flight mass...