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Coronavirus News is a section dedicated to the new coronavirus that is causing an epidemic in China and fast spreading globally. The strain of coronavirus called Covid-19 or also commonly called the Wuhan coronavirus is genetically more potent and faster spreading than the SARS coronavirus. Currently teams are working to develop a new vaccine for this new coronavirus while other teams are trying t...
Source: COVID-19 Aerosol Box Jul 11, 2020 5 years ago
COVID-19 Aerosol Boxes meant to protect doctors and nurses when they intubate COVID-19 patients may actually increase their exposure to airborne SARS-CoV-2 coronavirus particles according to a new Australian study.
The study findings are published in the journal: Anaesthesia,the official journal of the Association of Anaesthetists. https://onlinelibrary.wiley.com/doi/full/10.1111/an...
COVID-19 Latest: Emerging research from China shows that certain COVID-19 patients without a previous diagnosis of diabetes are showing abnormally high blood sugar and this is often associated with more than double the risk of death and also an increased risk of severe complications. One of the possible explanations for this phenomenon is that the endocrine system is being affected along wit...
COVID-19 News: Researchers from the University Of Basel have published a new study that focuses of the epidemiology of SARS-CoV-2 emergence amidst Community-Acquired Respiratory Viruses(CARVs) with implications of what we can expect in the coming winter.
The study traces how COVID-19 became the predominant cause of respiratory infection in the period from early January until the present. ...
New Viral Pneumonia:The Chinese embassy in Kazakhstan has warned of a deadly “unknown pneumonia” after the former Soviet republic reported a spike in pneumonia cases since June.The embassy that that is not the current SARS-CoV-2 coronavirus but stopped short of saying what it was.
The embassy said in a warning to Chinese citizens in the country, “The death rate of this disease ...
Source: COVID-19 Diagnostics Jul 10, 2020 5 years ago
COVID-19 Diagnostics: American researchers led by the Cedars-Sinai Medical Center and University Of Connecticut have developed highly specific and sensitive assays that could improve understanding of the antibody response in the COVID-19 disease and also help to determine the effectiveness of vaccines.
The new assays uncovered dynamic changes in the level of antibodies against the SARS-Co...
Source: U.S. Medical News Jul 10, 2020 5 years ago
US COVID-19 News: America posted 65,551 new COVID-19 cases in the last 24 hours, a record for a 24-hour period, according to a tally by Johns Hopkins University.
USA is the hardest-hit country in the world by the pandemic, has a total caseload of more than 3.22 million, with 135,018 deaths. (As of 10th July, 3am California,m Source Worldometer)
It was also reported that more ...
Source: COVID-19 Clinical Trials Jul 10, 2020 5 years ago
COVID-19 Clinical Trials: Medical researchers from the University of California San Diego School of Medicine have launched a clinical trial to assess the safety and efficacy of convalescent plasma to prevent COVID-19 after a known exposure to the virus.
Convalescent plasma therapy involves infusing patients with antibodies extracted from the blood of donors who have successfully...
Source: COVID-19 Clinical Trials Jul 10, 2020 5 years ago
COVID-19 Clinical Trials: Medical researchers are saying that low-dose radiation therapy seems to improve outcomes for COVID-19 patients. At least a dozen clinical trials are underway throughout the world to further explore the benefits. https://clinicaltrials.gov/ct2/results?cond=COVID-19&term=low-dose+radiation&cntry=&state=&city=&dist=
The latest two trial...
Source: COVID-19 Vaccines Jul 10, 2020 5 years ago
COVID-19 Vaccines: The U.S.National Institute of Allergy & Infectious Diseases (NIAID) has founded a new clinical trials network focused on enrolling volunteers in clinical trials for COVID-19 vaccines and monoclonal antibodies.
Various media have recently reported that sponsor companies are struggling to enroll patients in clinical trials for COVID-19 va...
Source: COVID-19 Controversies Jul 10, 2020 5 years ago
COVID-19 Controversies: Despite the fact that Pharmaceutical giant Gilead has huge resources and research facilities, it was never demonstrated that Remdesivir had any direct effects in terms of inhibiting the SARS-CoV-2 replication capability in vitro or vivo studies. The only things it had that made the Trump administration pass the FDA approval as a drug for COVID-19 was 'half-baked' st...
COVID-19 Drugs: Despite numerous studies showing that Lopinavir and Ritonavir are not effective to treat COVID-19, we still have numerous ignorant countries and doctors still using those drugs in their treatment protocols.
Now a new French study shows that older, critically ill patients with COVID-19 who received a combination of the antiretroviral medications lopinavir and ritonavir experienced ...
Source: COVID-19 Genomics Jul 09, 2020 5 years ago
COVID-19 Genomics: University Of Otago-New Zealand researchers studying the SARS-CoV-2 coronavirus has discovered that a particular binding site of virus targeting host microRNA miR197-5p has mutated more than 40 times since March and is now present in more than 75 percent of SARS-CoV-2 global isolates. The findings also have implications for cardiovascular issues.
The research findings w...
COVID-19 Drugs: There is now an increased demand for a variety of drugs to treat the growing variety of symptoms and conditions associated with COVID-19. One of which is the assortment of different types of neurological conditions. Just for one neurological category of symptoms which is delirium, BioXcel Therapeutics, which is based in Connecticut has developed a new drug called BXCL510.
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COVID-19 Drugs: R-Pharm, a Russian pharmaceutical company has secured regulatory approval for the use of its antiviral drug Coronavir, to treat patients suffering from Covid-19. The company released the announcement today to Russian media.
The regulatory approval comes after a clinical trial in mild to moderate Covid-19 patients showed that the drug is highly effective in blocking replica...
Source: COVID-19 Genomics Jul 09, 2020 5 years ago
COVID-19 Genomics: Swiss Researchers from the Institute of Molecular Biology and Biophysics-Zurich, University of Bern and Institute of Virology and Immunology-Bern have discovered the detailed functional process by which the SARS-CoV-2 coronavirus NSP1 Protein Inhibits Host Translation.
Their study published in a preprint server shows that the 5’ end of the RNA molecule is ca...
Source: COVID-19 Disinfectants Jul 09, 2020 5 years ago
COVID-19 Disinfectants: The American Environmental Protection Agency (EPA) just approved two disinfection sprays that can kill severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), on surfaces. The agency gave the green light to Lysol Disinfectant Spray, and Lysol Disinfectant Max Cover Mist, as two products that can effectively kil...
Source: COVID-19 Nutrition Jul 09, 2020 5 years ago
COVID-19 Nutrition: A new but intriguing European study involving the collaboration of 13 research centers and universities in Germany, Spain, Portugal, Franca and Switzerland suggests that COVID-19 mortality rates are likely to be lower in countries where diets are rich in fermented vegetables.
Though the study is published on a preprint server, it is currently being peer-reviewed by a f...
Source: COVID-19 Diagnostics Jul 09, 2020 5 years ago
COVID-19 Diagnostics: Researchers from the University of Exeter have developed a revolutionary new device that could allow health professionals to accurately test patients' antibody response to COVID-19 in as little as seven minutes.
The new pioneering COVID-19 Triple Antibody Test has been produced by the University of Exeter spin-out company Attomarker Ltd and is set to spearhead th...
COVID-19 Alert: Medical researchers from Cedars-Sinai Medical Center, Michigan Medicine and UCLA Fielding School of Public Health have found an association between proton pump inhibitors (PPIs) and risk of COVID-19 in an observational study of more than 53,000 Americans.It was found that PPIs usage was linked with a higher risk for COVID-19.
This places the usage of PPIs for heartburn and gastric...
Source: COVID-19 Antibodies Jul 08, 2020 5 years ago
COVID-19 Antibodies: Researchers from Tulane University-New Orleans, University of Illinois-Chicago and University of Georgia have created a synthetic antibody that on mouse models demonstrated to neutralize the SARS-CoV-2 coronavirus. This could help prevent infection as well as treat COVID-19 in those who already have it.
Typically the SARS-CoV-2 coronavirus, gains entry into cells...
Source: COVID-19 Research Jul 08, 2020 5 years ago
COVID-19 Research: German researchers from Max Planck Institute, Frankfurt Institute for Advanced Studies and the Institute of Biophysics, Goethe University-Frankfurt have conducted a news study on the structural dynamics of the SARS-CoV-2 spike protein and have identified epitopes that could be possible immune targets for the development of vaccines or other therapeutics.
The resear...
Source: COVID-19 Neurology Jul 08, 2020 5 years ago
COVID-19 Neurology: German researchers from Charité - Universitätsmedizin Berlin have shown that the neurological symptoms observed in some COVID-19 patients may be caused by autoantibodies targeting the brain.
The research team says that although some autoantibodies still need to be identified, they may at least partly explain the multiple organ disease that can occur in COVI...
COVID-19 Drugs: Medical researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection.
Research has shown that some corticosteroids,&nbs...
Source: COVID-19 Innovations Jul 08, 2020 5 years ago
COVID-19 Innovations: Experts from the University of Houston, in collaboration with a private company called Medistar, have designed a "catch and kill" air filter that can trap the coronavirus responsible for COVID-19, killing it instantly.
Dr Zhifeng Ren, director of the Texas Center for Superconductivity at UH, collaborated with Monzer Hourani, CEO of Medistar, a Houston-based...
Source: COVID-19 Vaccine Updates Jul 08, 2020 5 years ago
COVID-19 Vaccine Updates: Maryland based Biotech company Novavax announced that it has been awarded US$1.6 billion toward late-stage clinical trials and large-scale manufacturing to produce 100 million doses of its COVID-19 vaccine starting this year through the Trump’s administration “Operation Warp Speed” program.
The new funding will enable Novavax to complete la...
Source: COVID-19 Neurology Jul 08, 2020 5 years ago
COVID-19 Neurology: A new study by University College London (UCL) and University College London Hospitals (UCLH) indicate that more neurological conditions are being manifested in COVID-19 patients. Besides delirium, brain inflammation, stroke and nerve damage, a large number of patients are now shown to be inflicted with ADEM or Acute Disseminated Encephalomyelitis and its prevalence is gr...
Source: Guillain-Barre Syndrome And COVID-19 Jul 08, 2020 5 years ago
Guillain-Barre Syndrome: A new peer-reviewed study published in the Journal of Clinical Neuromuscular Disease by researchers from Department of Neurology and Neuroscience Institute, Allegheny General Hospital Pittsburgh, Pennsylvania show that COVID-19 is linked with Guillain-Barre Syndrome. https://journals.lww.com/jcnmd/FullText/2020/06000/Novel_Coronavirus__COVID_19__Associated.7.aspx
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Source: COVID-19 Clinical Care Jul 08, 2020 5 years ago
COVID-19 Clinical Care: A new study by researchers from Boston Children’s Hospital warns about how and when type III Interferons should be used in the treatment of COVID019 as using it in later stages of severity can do more harm.
The research findings were published in the journal: Science. https://science.sciencemag.org/content/early/2020/06/10/science.abc3545
The human imm...
Source: COVID-19 Research-Liver Fibrosis Jul 07, 2020 5 years ago
COVID-19 Research: According to researchers in Spain, middle-aged COVID-19 patients showing signs of advanced liver fibrosis, as estimated by the Fibrosis Index Based on 4 Factors (FIB-4), are at greater likelihood of requiring mechanical ventilation.
Dr Luis Ibanez-Samaniego from the Hospital General Universitario Gregorio Maran, in Madrid who is the lead researcher said that not m...
Source: COVID-19 Warnings- Captopril Jul 07, 2020 5 years ago
COVID-19 Warnings: A US based study involving researchers from University of Missouri Kansas City School of Pharmacy, Kansas State University and North Carolina State University has found that the high blood pressure drug Captopril to be associated with a higher rate of pulmonary adverse reactions in patients with diabetes than that of other ACE inhibitors or angiotensin receptor blockers (ARBs).
...
Source: COVID-19 Seroprevalence Jul 07, 2020 5 years ago
COVID-19 Seroprevalence: The Spanish ENE-COVID national seroprevalence study concludes that 5% of its population has antibodies. This percentage has hardly changed in the three waves of which the study consists: in the first it was estimated at 5% and in the second and third it was 5.2%, results that confirm that, despite the great impact of the pandemic in Spain, the figures are not high, which r...
Source: COVID-19 Case Study Jul 07, 2020 5 years ago
COVID-19 Case Study: Numerous patients with severe COVID-19 remain unresponsive after surviving critical illness. Medical Researchers from Massachusetts General Hospital (MGH) presents a case in which a patient with severe COVID-19 who, despite prolonged unresponsiveness and structural brain abnormalities, demonstrated functionally intact brain connections when functional MRI was used and we...
Source: COVID-19 Research Jul 07, 2020 5 years ago
COVID-19 Research: In a new study by researchers from US NIH, Columbia University and John Hopkins University, it has been shown that the SARS-CoV-2 coronavirus is proving itself to be an elusive foe, evading immune surveillance while instigating hyper-inflammatory responses that eventually destroy the host in a significant minority of cases. The study reports the role of pH in helping the virus e...
Source: COVID-19 Vaccine News Jul 07, 2020 5 years ago
COVID-19 Vaccine News: Biotech manufacturing company-Emergent BioSolutions, based in Maryland, entered a five-year manufacturing services deal with Janssen Pharmaceutical, a Johnson & Johnson company, to manufacture J&J’s Ad26.COV2-S COVID-19 vaccine. Emergent will handle contract development and manufacturing (CDMO) services in a deal that is valued at ...
Source: COVID-19 Antibodies Jul 07, 2020 5 years ago
COVID-19 Antibodies: New York based Regeneron Pharmaceuticals announced its double-antibody cocktail against COVID-19 is advancing into Phase III studies, less than a month after the start of its first clinical trial, with preliminary data from one study expected to be reported later this summer.
Regeneron's Biotech Plant
The biotech company said it is proceeding with clinical develop...
Source: COVID-19 Medical Devices Jul 07, 2020 5 years ago
COVID-19 Medical Devices: To date, emerging studies suggests that COVID-19 patients are at a higher risk of stroke and promptly diagnosing and treating such patients is a priority in hospitals across the world.
Furthermore, identifying which COVID-19 patients are at increased risk of developing a stroke is also important, and may help with preemptive treatment and monitoring.
Los A...
Source: COVID-19 Vaccine Updates Jul 07, 2020 5 years ago
COVID-19 Vaccine Updates: It was announced that vaccine candidate COVAX-19 developed by Vaxine Pty Ltd and Flinders University will commence Phase 1 trials at the Royal Adelaide Hospital (RAH) to test its efficacy.
The phase I trial will provide initial safety and immune response data on 40 healthy participants aged between 18 and 65 years who have already been pre-screened.
Resear...
COVID-19 Drugs: Researchers from University of South Florida Health (USF Health) Morsani College of Medicine scientists along with pharmaceutical experts from the University of Arizona College of Pharmacy have identified several existing drug compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The identified inhibitors all demon...
Source: COVID-19 Research Jul 07, 2020 5 years ago
COVID-19 Research: A new study by Dr Anna Aksenova, a senior research associate at the Laboratory of Amyloid Biology at St Petersburg University, has advanced a hypothesis that the severe course of COVID-19 may be associated with the von Willebrand factor, a blood glycoprotein that is one of the main components of the blood coagulation system.
The research findings have been peer re...
Source: COVID-19 Research Jul 07, 2020 5 years ago
COVID-19 Research: A research in which US Military bioweapon researchers tested the stability of the SARS-CoV-2 pathogen on various surfaces, including paper currency and pig skin showed that the novel coronavirus can live for days on animal skin at room temperature and even up to 2 weeks on refrigerated pig skin.
The study has huge implications in the food industry, meat processing plant...
We apologize to readers first for posting such an article on our site but we simply just could not resist the kind of stupidity materializing from the COVID-19 pandemic!
While many Americans and Europeans are refusing to wear protective mask against the SARS-V-2 coronavirus either due to political reasons or sheer stupidity, across the globe in India, we have the protective mask evolving into a f...
Source: Bubonic Plague China Jul 06, 2020 5 years ago
Bubonic Plague: China health authorities have reported an outbreak of Bubonic Plague in the inner Mongolia Autonomous Region.
Bubonic plague, caused by bacterial infection, was responsible for one of the deadliest epidemics in human history ie the Black Death which killed about 50 million people across Africa, Asia and Europe in the 14th Century.
There have been a handful of ...
Source: COVID-19 Genomics Jul 06, 2020 5 years ago
GOVID-19 Genomics: A major genetic risk variant found on the SARs-CoV-2 coronavirus RNA which comprises of a stretch of six genes that seems to increase the risk of severe illness from the coronavirus was found to be part of a stretch of DNA passed down from Neanderthals 60,000 years ago, according to a new study by genomic experts from the Max Planck Institute for Evolutionary Anthropology-German...
COVID-19 Vaccine: Professor of vaccinology at the University of Oxford, and one of the scientists leading the vaccine initiative, Dr Sarah Gilbert, told the U.K.'s Science and Technology Committee last week that their candidate vaccine has progressed to the phase III trial in the United Kingdom.
Phase III trials typically involves tens of thousands of research participants acros...
Flu Vaccine: Researchers from the Swiss Tropical and Public Health Institute, the University of Basel and University of Sao Paulo Medical School in a new research involving over 92,000 patients with COVID-19 in Brazil shows that the risks of severe disease, ventilatory support requirement, and death are reduced with a recent trivalent influenza vaccine.
The research findings were printed on a pre...
Source: COVID-19 Diagnostics Jul 06, 2020 5 years ago
COVID-19 Diagnostics: A new research from the University of Virginia (UVA) School of Medicine suggests doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator. The main biomarker that should be looked out for is the cytokine IL-13 (Interleukin 13). High levels of IL-13 were associated with worsened...
Source: Generic Remdesivir Jul 06, 2020 5 years ago
Generic Remdesivir: The Trump administration last week proudly announced that it had secured 500,000 doses of Gilead’s remdesivir at prices that were set by Gilead at between US$2,340 to US$3,120. https://www.thailandmedical.news/news/breaking-remdesivir-gilead-sets-price-at-us$2,340-to-us$3,120-for-drug-that-has-no-safety-studies-or-true-efficacy-except-that-it-shortens-hospitaliza
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Source: SARS-CoV-2 Is Airborne Jul 06, 2020 5 years ago
WHO: Despite mounting evidence that the SARS-CoV-2 coronavirus is airborne and that the general public worldwide needs to be aware of this, the WHO (World Health Organization) is still taking a stance that it is not the case but is only spread by large respiratory droplets that, once expelled by infected people in coughs and sneezes, fall quickly to the floor.
The WHO lead by black ...
Source: COVID-19 Diagnostics Jul 05, 2020 5 years ago
COVID-19 Diagnostics: The US FDA last week on granted Emergency Use Authorization to a new molecular diagnostic test from the US Centers for Disease Control and Prevention that can detect and differentiate the viruses that cause COVID-19 and flu.
The new Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay is a real-time RT-PCR test intended for the simultaneous detection and differ...
Source: COVID-19 Innovations Jul 05, 2020 5 years ago
COVID-19 Innovations: The current COVID-19 pandemic has brought a slew of new challenges for clinical facilities, including how to deliver as much care as possible at a distance or remotely not only for precautionary measures to safeguard the wellbeing of healthcare staff but only for better monitoring of COVID-19 patients..
Researchers from the Department of Cardiovascular Medicine at To...
COVID-19 And HIV: Individuals with HIV who were hospitalized with COVID-19 did not have worse results than COVID-19 patients without HIV, according to new research by Icahn School of Medicine at Mount Sinai.
The research findings were published in the journal: Clinical Infectious Diseases https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa880/5864410?searchresult=1
Study...
COVID-19 Pharma News: Pharma giant Merck, a leading science and technology company, announced that the US FDA has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. Merck will initiate a Phase II randomized, controlled clinical study evaluating the safety and efficacy of M5049 in this patient population. M5049 is a potentially fi...
Source: Melatonin and COVID-19 Jul 05, 2020 5 years ago
Melatonin and COVID-19: Another study by researchers from Peking Union Medical College in China and the University of Texas- San Antonio in America have in a new peer-reviewed finding that is published in the journal: Life Sciences By Science Direct, propose that Melatonin should be incorporated as an adjuvant treatment for COVID-19 as it has proven mechanisms to target Inflammasomes that triggers...
COVID-19 Vaccine: Researchers from China have created an artificial protein that they say could be the basis of a vaccine to help ward off various deadly coronaviruses, including the pathogen that causes Covid-19
Copyright: Credit: Xinhua
The researchers from the Chinese CDC said the approach triggered a strong antibody response in mice and monkey trials to Middle Eas...
Source: COVID-19 Clinical Care Jul 04, 2020 5 years ago
COVID-19 Clinical Care: Researchers are expressing that more safety data is needed in terms of treatment of symptomatic COVID-19 patients on antivirals with anticancer drugs.
A report published in the European Journal of Cancer by a group of French investigators led by Dr Paul Gougis of the Department of pharmacology, Hôpital Pitié-Salpêtrière in Paris, Franc...