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Coronavirus News is a section dedicated to the new coronavirus that is causing an epidemic in China and fast spreading globally. The strain of coronavirus called Covid-19 or also commonly called the Wuhan coronavirus is genetically more potent and faster spreading than the SARS coronavirus. Currently teams are working to develop a new vaccine for this new coronavirus while other teams are trying t...
COVID-19 Drugs: EUSA Pharma has secured approval from the U.S. Food & Drug Administration (FDA) for a Phase III clinical trial protocol of intravenous siltuximab plus standard of care in hospitalized patients with Covid-19 associated Acute Respiratory Distress Syndrome (ARDS).
The pharmaceutical company will now proceed with the randomized, double-blind, placebo-controlled clinical trial to e...
COVID-19 Vaccine: Indian pharmaceutical company, Zydus Cadila received the green signal from the Drug Controller General of India (DGCI) to start phase I and II of their clinical trials on human participants.
Over 120 independent scientific bodies are in contention to find a potential COVID-19 vaccine. Over 7 vaccines are being researched in India and just this week, two candidate groups ...
Source: COVID-19 Vaccine Updates Jul 04, 2020 5 years ago
COVID-19 Vaccine Updates: Pharmaceutical and Biotech giants, Pfizer and BioNTech reported that the most advanced of four constructs of their messenger RNA (mRNA) vaccine candidate for COVID-19 showed encouraging immunogenicity and a favorable safety profile in preliminary Phase I/II data published in a preprint study. https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1
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Source: COVID-19 Disinfectants Jul 04, 2020 5 years ago
COVID-19 Disinfectants: University of Manchester scientists say that a little-known non-toxic antiseptic developed in the Soviet Union during the Cold War has enormous potential to beat common infections and that even detailed studies should be conducted with regards to its use in the current COVID-19 scenario. Their report was published in the journal: FEMS Microbiology Reviews. https://aca...
Source: Chronic Fatigue Syndrome Jul 04, 2020 5 years ago
Chronic Fatigue Syndrome: There has been so many clinical manifestation of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) reported in COVID-19 patients experiencing mild to moderate symptoms and also in typically asymptomatic and also recovered COVID-19 patients. To date medical experts do not have a proper explanation for this.
However, browsing through various new COVI...
Source: COVID-19 Research Jul 04, 2020 5 years ago
COVID-19 Research: Researchers from the University Of Bristol in a new review published in the Journal Of Infection indicate that liver complications are common and are associated with more severe disease in patients with COVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306105/ or https://www.journalofinfection.com/article/S0163-4453(20)30425-4/pdf
Dr Setor K. Kunutsor of Bristol M...
Source: COVID-19 Pediatrics Jul 04, 2020 5 years ago
COVID-19 Pediatrics: Researchers from the University College London Institute of Neurology are warning that children with COVID-19 may present with new neurological symptoms involving the central and peripheral nervous systems, and splenial changes on imaging.
The new research findings were published the journal: JAMA Neurology.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2...
COVID-19 Drugs and Erythropoietin: German researchers from the Max Planck Institute of Experimental Medicine in Göttingen suggest that the anemia drug Erythropoietin (Epo) which is sometimes misused as doping agent could also be effective against COVID-19.
EPO, the growth factor could also mitigate severe disease progression and protect patients from long-term neurological effects when the ...
Source: SARS-COV-2 Mutations Jul 03, 2020 5 years ago
SARS-COV-2 Mutations: Virologists and genomic researchers now know that two major variants of the novel coronavirus (SARS-CoV-2) are circulating in the United States and elsewhere at the moment besides the hundreds of minor variants. The variants, called G614 and D614, have just a small difference in their "spike" protein, the viral machinery that coronaviruses use to enter hos...
Source: U.S. COVID-19 News Jul 03, 2020 5 years ago
U.S. COVID-19 News: America sets a new record in the last 24 hours with 53,069 (Thursday) new coronavirus infections in the last 24 hours. The country now has recorded a total of 2,837,189 COVID-19 Infections of which health authorities claim that 1,191,102 have ‘recovered.’ A total of 131,217 Americans have died from the COVID-19.
What is even scarier is that it is reported t...
Source: COVID-19 Diagnostics Jul 03, 2020 5 years ago
COVID-19 Diagnostics: Despite the fact that accurate and widespread testing is crucial to managing the coronavirus pandemic, many individuals in the U.S. and even elsewhere globally still can’t get tested for COVID-19 without visiting designated sites.
A rendering of a potential affordable, handheld COVID-19 testing device.
The researchers hope to be evaluating prototyp...
COVID-19 Drugs: Researchers from the University of North Carolina (UNC) have used a new web-based platform to help identify synergistic and antagonistic drug combinations and their underlying mechanisms of action in the context of fighting the SARS-CoV-2 coronavirus disease.
The data mining tool, called COVID-KOP, prioritized 73 combinations of 32 drugs as potential treatments for COVID-1...
Source: COVID-19 and Strokes Jul 03, 2020 5 years ago
COVID-19 and Strokes: A new study finds that although both Influenza and COVID-19 can raise the risk for a stroke, the odds appear to be eight times higher with the SARS-CoV-2 coronavirus.
The researchers found that among more than 1,900 patients with COVID-19, 1.6% suffered a stroke, versus 0.2% of nearly 1,500 patients seriously ill with flu.
The research findings ...
COVID-19 Hypoxia: Researchers from Hines Veterans Affairs Hospital and Loyola University of Chicago in a new study provides possible explanations for COVID-19 patients who present with extremely low, otherwise life-threatening levels of oxygen, but no signs of dyspnea (difficulty breathing). This new understanding of the condition, known as silent hypoxemia or 'happy hypoxia,' could ...
Source: COVID-19 and the Endocrine System Jul 02, 2020 5 years ago
COVID-19 Endocrine System: It seems that the damage from the SARS-CoV-2 coronavirus is never ending. Starting out initially as a respiratory disease that causes damage to the lungs, studies progressed to show that it also affects the immunity system, the gastroenterological system, the clotting mechanisms, the neurological system, the heart and circulatory system, the reproductive system in males ...
Source: COVID-19 Recovered Patients Jul 02, 2020 5 years ago
COVID-19 Recovered Patients: A collaborative study in China involving leading universities and hospitals headed by Wuhan Institute Of Virology has discovered that recovered patients who even after 2 to 11 weeks of being discharged from hospitals, displayed a remarkable phenotypic alterations in lymphocytes after clinical recovery. This suggests SARS-CoV-2 infection imprints profoundly on lymphocyt...
Source: Diabetes and COVID-19 Jul 02, 2020 5 years ago
Diabetes And COVID-19: A case study by German researchers from University of Kiel have confirmed that the Sars-CoV-2 coronavirus can trigger diabetes and insulin dependency in young adults who have otherwise been healthy with any prior history of sickness or diabetes. It is assumed that the diabetes is triggered by the SARS-CoV-2 coronavirus attacking the pancreas thru the ACE-2 receptors present ...
Source: COVID-19 Diagnostics Jul 02, 2020 5 years ago
COVID-19 Diagnostics: Researchers from the Innovative Genomics Institute (IGI), the same UC Berkeley group that rapidly popped up a state-of-the-art COVID-19 testing laboratory in March, are now trialing a quicker way to obtain patient samples: through saliva.
So far diagnostic tests for COVID-19 have relied on samples obtained by swabbing uncomfortably deep into a person’s nasal pa...
US Medical News: Daily new COVID-19 cases in America soared past 51,097 in the last 24 hours for the first time, as the World Health Organization delivered a grave warning that the global pandemic is accelerating.
Clubs, restaurants, bars and beaches in the world's worst-hit nation closed from California to Florida, as states reeling from yet another surge in the deadly virus&nbs...
COVID-19 Latest: Researchers from Utrecht University, UMC Utrecht, and Erasmus MC have discovered that platelets also play a role in the immune system: They appear to be indispensable in protecting the respiratory system against pathogens despite their primary role in blood coagulation and the development of thrombosis.
Lead researcher Dr Erhard van der Vries told Thailand Medical News, &...
Source: COVID-19 Drugs and Fostamatinib Jul 02, 2020 5 years ago
COVID-19 Drugs: Fostamatinib, an FDA-approved monoclonal antibody that is a spleen tyrosine kinase inhibitor (SYK), was studied by researchers from Harvards’ Broad Institute, Imperial College’s Hammersmith Hospital, Brigham and Women’s Hospital and Harvard Medical School for possible use to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respi...
Source: COVID-19 Endotheliopathy Jul 02, 2020 5 years ago
COVID-19 Endotheliopathy: Yale University researchers have found that injury to endothelial cells ie the cells lining blood vessels may be a key driver of COVID-19 severity and death.
The new research may help to explain the mysterious blood clotting seen in some patients with COVID-19, a condition associated with the most severe cases and death. The discovery suggests that doctors could ...
Source: COVID-19 Antibodies Jul 02, 2020 5 years ago
COVID-19 Antibodies: A new research published by the British Medical Journal, (BMJ) yesterday highlights major weaknesses that exist in the evidence base for COVID-19 antibody tests. https://www.bmj.com/content/370/bmj.m2516
The research found that the evidence is particularly weak for point-of-care tests (performed directly with a patient, outside of a laboratory) and does not support...
Source: World Covid-19 News Jul 01, 2020 5 years ago
World Covid-19 News: The world has recorded 10,614,957 official COVID-19 infections and 514,635 deaths in the last six months as of Ist July 2020 (5am California). The actual figures are at least 5 fold for both infection and deaths due to underreporting and concealments by many countries. Unfortunately despite the relative high figures, people are still complacent and many are living in denial. (...
Source: COVID-19 Disinfectants Jul 01, 2020 5 years ago
COVID-19 Disinfectants: PNNL or Pacific Northwest National Laboratory has created a new superhydrophobic material, called ElastiDry that repels bacteria and viruses.
Water beads off ElastiDry due to the substance’s superhydrophobocity.
Image credit: Andrea Starr | PNNL
PPEs or personal protective equipment has been at the center of the fight against COVID-19. The unforgiving...
COVID-19 Vaccine: Medical experts from UK are saying that a vaccine against COVID-19 may not be as effective in older people who are most at risk of suffering complications and dying from the disease.
A better approach they say is to immunize those around the elderly to better help them and also protect them from getting infected those close to them or are in constant with them.
Pr...
Source: COVID-19 Clinical Trials Jul 01, 2020 5 years ago
COVID-19 Clinical Trials: Researchers from RCSI University of Medicine and Health Sciences-Ireland have begun a clinical trial of a promising therapy for critically ill COVID-19 patients in intensive care.
A study published in the American Journal of Respiratory and Critical Care Medicine by the team led by RCSI Professors Dr Gerry McElvaney and Dr Ger Curley, describe changes in the...
Source: COVID-19 Neurology Jul 01, 2020 5 years ago
COVID-19 Neurology: A research team comprising of multidisciplinary experst from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains&...
Source: COVID-19 Genomics Jul 01, 2020 5 years ago
COVID-19 Genomics: Genomic researchers from Norway and the US demonstrate the presence of a highly conserved, mobile genetic element (thus far with unknown function) in genomes of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a large number of insects, opening the door for hitherto unexplored treatment opportunities.
The coronaviruses are a group of known human...
COVID-19 Drugs: The SARS-CoV-2 coronavirus typically uses a protein called polymerase to replicate its genome inside infected human cells. Studies have shown that terminating the polymerase reaction will stop the growth of the coronavirus, leading to its eradication by the human host's immune system.
Now researchers from Columbia University and the University of Wisconsin-Madison have...
Source: COVID-19 Myocarditis Jul 01, 2020 5 years ago
COVID-19 Myocarditis: Researchers from Mount-Sinai have in a new study showed that the SARS-CoV-2 coronavirus can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.
The new discovery, published in the journal Cell Reports Medicine, was made using heart muscle cells that were produced by stem cell ...
Source: New G4 EA H1N1 Swine Flu Strain Jun 30, 2020 5 years ago
New G4 EA H1N1 Swine Flu Strain: A team of researchers affiliated with a host of institutions in China and one in the U.S. has found evidence of a new strain of swine flu that poses a possible threat to humans based on widespread testing of pigs in China and people known to be near them.
The research finds are published in the journal: Proceedings of the National Academy of Sciences...
COVID-19 Drugs: More emerging results from the ongoing international RECOVERY Trail project shows that Lopinavir-Ritonavir has no clinical benefits in hospitalized COVID-19 treatments. Readers should also take note that in February 2020, Thai ‘medical experts’ held a huge press conference to announce that they had invented a treatment protocol to treat COVID-19 using Lopinavir-Ritonavi...
Source: COVID-19 Research Jun 30, 2020 5 years ago
COVID-19 Research: A new research by University Of Utah indicates that changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease.
The study team found that inflammatory proteins produced during infection significantly alter the function of platelets, making them "hype...
Source: Multisystem Inflammatory Syndrome Jun 30, 2020 5 years ago
Multisystem Inflammatory Syndrome: Till May 2020, at least 285 children in America alone have developed a serious inflammatory condition linked to the SARS-Cov-2 coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies published in the New England Journal of Medicine suggest. These are the most detailed reports yet on the condition.
https://...
Source: COVID-19 Research Jun 30, 2020 5 years ago
COVID-19 Research: Researchers from University of Utah Health and PEEL Therapeutics, in collaboration with Cold Spring Harbor Laboratory and Weill Cornell Medicine, report in a new study that an overactive defense response may lead to increased blood clotting, disease severity, and death from COVID-19. A phenomenon called NETosis in which infection-fighting cells emit a web-like substance to trap ...
Source: PTSD and COVID-19 Jun 30, 2020 5 years ago
PTSD: The COVID Trauma Response Working Group, which includes mental health experts from King’s College London, University College London, Oxford University, the University of Haifa in Israel, and the NHS, are warning that those who have been admitted in intensive care units or even just hospitalized for COVID-19, would have been seriously ill enough to develop PTSD (post-traumatic str...
Source: Health Tech Startups Jun 30, 2020 5 years ago
Health Tech Startups: A team of National University Of Singapore (NUS) researchers have developed a portable COVID-19 micro-PCR diagnostic system called Epidax that enables rapid and accurate on-site screening of infectious diseases and significantly reduces the time required to analyze patient samples. With this new innovation COVID-19 screening can soon be conducted directly at various testing s...
Source: Remdesivir and COVID-19 Jun 30, 2020 5 years ago
Remdesivir: No one is sure yet as to how much certain family members of Trump or the relatives of the US FDA could be making, but its interesting to see that the US FDA under the Trump administration had approved a drug to treat COVID-19 despite the fact there are no true detailed safety studies on the drug and also the fact there is no real efficacy demonstrated except that it shortens hospitaliz...
Cytokine Storms: Researchers from Medical University Of Lublin-Poland and University of Bonn-Germany have discovered that the SARS-CoV-2 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs). Yet this leads to widely diverse clinical symptoms, suggesting multiple pathogenic mechanisms.
The researchers als...
Source: COVID-19 Drugs & Vaccines Jun 29, 2020 5 years ago
COVID-19 Drugs And Vaccines: As the total number of global confirmed COVID-19 Infections reaches 10,267, 578 and the total confirmed deaths due to the SARS-CoV-2 coronavirus reaches 504, 812 (29th June, 2.45am California), people everywhere and healthcare professionals are getting more anxious as to date there are no real confirmed drugs or treatments protocols that can really treat COVID-19 effec...
COVID-19 Diets: Interestingly among the many approaches to COVID-19 prevention, the possible role of diet has so far been somewhat marginal. Nutrition is very rich in substances with a potential beneficial effect on health and some of these could have an antiviral action or in any case be important in modulating the immune system and in defending cells from the oxidative stress associated with inf...
Source: China COVID-19 News Jun 28, 2020 5 years ago
China COVID-19: As the situation comes under control, various part of China are witnessing sporadic burst of new COVID-19 cases. The latest is Hebei province. Roughly 600,000 residents in Hebei province have been placed under severe restrictions reminiscent of earlier lockdowns.
Chinese Health authorities are saying there are only 13 confirmed COVID-19 cases in Anxin, just 140 kilometres ...
US Medical News: America recorded 43,581 new COVID-19 cases in the last 24 hours (figures for Saturday) and 511 deaths due to COVID-19. As of 3am California time, the total number of COVID-19 infections has now reached 2,596,814 of which 1,081,494 have been deemed to have recovered according to US health authorities.
Only two US states have reported a decline in new coronavirus ...
Source: COVID-19 Immunology Jun 28, 2020 5 years ago
COVID-19 Immunology: Researchers from University Of California-San Diego, La Jolla Institute for Immunology-California and Eramus University medical College-Netherland report that patients suffering from severe respiratory symptoms as a result of SARS-CoV-2 infection can rapidly generate virus-attacking T cells, and can increase this production over time.
The researchers conducted a...
Source: COVID-19 Treatments Jun 28, 2020 5 years ago
COVID-19 Treatments: The oral administration of the amino-acids Cysteine and Theanine could attenuate SARS-CoV-2 viral infection, replication and associated symptoms of COVID-19 such as cytokine storm according to Japanese researchers from the Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc.
The preprint study that is yet to be peer-reviewed is publishe...
Source: SARS-CoV-2 Coronavirus Jun 28, 2020 5 years ago
SARS-CoV-2: Genomic researchers from the department of molecular biology and genetics, faculty of science, Sivas Cumhuriyet University-Turkey have done a detailed comparative phylogenomics study of various SARS-CoV-2 sequencings and their research findings indicate that the SARS-CoV-2 coronavirus most likely originated from Guangdong province and not Wuhan as originally though and that the coronav...
Source: COVID-19 Dermatology Jun 28, 2020 5 years ago
COVID-19 Dermatology: Reports are appearing in JAAD (Journal Of American Academy of Dermatology ) that numerous COVID-19 patients are now manifesting chicken-pox like lesions on their skin, a condition known as Varicella-like exanthema.
In one report submitted by Italian researchers and doctors, a study was made on 22 patients who displayed these dermatological symptoms. . https://www...
US Medical News: America is facing an exponential rise in COVID-19 cases. In the last 24 hours, 47,342 new cases were reported and the numbers are still rising. Though there were only 663 deaths, the number of critical patients are rising as well with hospitals bearing the stress. It was reported that there are currently more than 24,700 patients in critical conditions across the country.
...
Source: Occulus Hirsutus and AQCH Jun 27, 2020 5 years ago
Occulus Hirsutus and AQCH: For the past 4 months India has been secretly working with teams of medical, biotech, biomolecular and pharmaceutical experts in developing an antiviral drug to treat COVID-19 using extracted phytochemicals from the Occulus Hirsutus plant.
The plant Cocculus hirsutus (Linn.) Diels (Menispermaceae), described in traditional indian medicine ayurvedic literatu...
Source: COVID-19 Inflammation Jun 27, 2020 5 years ago
COVID-19 Inflammation: A new research lead by University of Bristol, University-UK, Max Planck Institute for Medical Research-Germany, Geneva Biotech Sàrl-Switzerland and other European entities have discovered a novel free fatty acid (FFA) binding pocket on the SARS-CoV-2 virus that could explain in part the viral effects of hyper inflammation, immune modulation, and membrane structure. Th...
Source: SARS-CoV-2 Coronavirus Jun 27, 2020 5 years ago
SARS-CoV-2 Coronavirus: There is still so much we do not know about the SARS-CoV-2 coronavirus and it reinforces the fact that there is also so much not known in the field of virology, which continues to challenge the ability of mankind to remain healthy when faced with pathogens. While most known microbes have restricted affinity for specific species, continuing to adapt within the host spe...
US Medical News: The total number of confirmed new COVID-19 cases per day in the U.S. hit an all-time high of 40,184 in the last 24 hours, eclipsing the mark set during one of the deadliest stretches in late April, in a resurgence that has led some governors to backtrack or at least pause the reopening of their states.
Though the increase is believed to reflect, in part, greatly expanded ...
Source: Oxygen Concentrators Jun 26, 2020 5 years ago
Oxygen Concentrators: The World Health Organization (WHO) head has said that the world is facing an acute shortage of oxygen concentrators as the number of worldwide cases of COVID-19 disease nears the 10 million mark.
WHO Director General Tedros Adhanom Ghebreyesus told media, "Many countries are now experiencing difficulties obtaining oxygen concentrators. Demand is currently outst...
Source: COVID-19 Neurological And Psychiatric Complications Jun 26, 2020 5 years ago
COVID-19 Neurological And Psychiatric Complications: A collaborative study involving numerous institutions and hospitals including University of Cambridge, University Hospital Southhampton, King’s College London, University of Manchester, University of Newcastle, University of Edinburg, University Of Liverpool, University College London, and others, which focused on neurological and psychiat...