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SARS-CoV-2 News - Tight Junction Protein Occludin Apr 20, 2023 2 years ago
SARS-CoV-2 News: A new study by researchers from University of Missouri, Columbia-USA has found that that tight junction protein Occludin is an internalization factor for SARS-CoV-2 infection and mediates virus cell-to-cell transmission.
SARS-CoV-2, the virus responsible for COVID-19, spreads easily from person to person. Understanding how it enters and infects cells is crucial for develo...
COVID-19 News: While some ignorant and attention seeking COVID-19 ‘experts’ in India claimed that the COVID-19 situation was peaking in India, emerging real time data is showing that the COVID-19 situation in India is far from peaking with hospitalizations now increasing and healthcare staff now starting to feel the stress.
Image Credit: Danish Siddiqui/Reuters
It was reported...
COVID-19 News - Two Lab Leaks and a Secret Vaccine Apr 19, 2023 2 years ago
COVID-19 News: In a groundbreaking revelation, Kansas Senator Dr Roger Marshall has unleashed an explosive 300-page report, claiming that the coronavirus pandemic was triggered by not one, but two separate lab leaks in China. This sensational report, containing more than 1,500 citations, has not only uncovered the long-concealed truth about the origins of COVID-19 but also disclosed China's se...
COVID-19 News: On Tuesday, Japan's health ministry reported 11,589 new cases of COVID-19 and 20 deaths. The number of seriously ill patients declined by two from Monday, totaling 55. In comparison to the previous week, new case numbers increased in 37 prefectures and decreased in 10 others.
Tokyo experienced a significant rise in cases, with 1,696 new infections, up 206 from a week ag...
COVID-19 News - Thymosin Alpha 1 Apr 18, 2023 2 years ago
COVID-19 News: Thymosin α1 (Tα1) is a small but mighty immunostimulatory peptide that has been making waves in the field of viral infectious diseases. It has emerged as a powerful immune enhancer in the fight against formidable foes such as hepatitis B, hepatitis C, and AIDS. This miraculous peptide has the ability to influence the functions of various immune cells, like T cells, B cel...
COVID-19 News: Malaysia is witnessing a concerning surge in COVID-19 cases just before the Hari Raya Aidilfitri celebrations, raising fears of a new wave of infections. Public health experts are urging citizens to mask up once more and take necessary precautions to prevent further spread of the virus.
In the 14 days leading up to April 8, the number of confirmed COVID-19 cases in Malaysia...
COVID-19 News - Circulating T Follicular Helper Cells Apr 17, 2023 2 years ago
COVID-19 News: The SARS-CoV-2 pandemic has revealed a wide range of clinical outcomes among infected individuals, from asymptomatic to severe cases. While scientists have identified some factors that could affect the severity of the disease, the exact immunological parameters behind these varying outcomes remain unclear.
A study team from Karolinska Institutet and Karolinska University Ho...
COVID-19 News - COVID-19 Variants Apr 16, 2023 2 years ago
COVID-19 News: As the SARS-CoV-2 pandemic continues to wreak havoc worldwide, a groundbreaking new study by American researchers suggests that relying solely on vaccination efforts may not be enough to slow the rapid emergence of immune-evading SARS-CoV-2 variants. This bombshell report could turn the world's entire approach to managing the ongoing COVID-19 crisis on its head!
The res...
COVID-19 News -Novel Fold - Nsp9 Apr 16, 2023 2 years ago
COVID-19 News: The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a devastating impact on global health and the economy. The development of vaccines and therapeutic agents targeting various viral components is crucial to combat the virus effectively. In a recent study by researchers from Monash University-Australia, the study team uncovered a...
U.S. Medical News - XBB.1.16 Gaining Traction In America Apr 15, 2023 2 years ago
U.S. Medical News: Despite concerted efforts by the Biden administration to conceal the real impact of the COVID-19 crisis in the country, certain public figures that cannot be concealed or downplayed are indicating that the country should brace itself for another offensive onslaught by various new XBB sub-lineages including the XBB.1.16 and XBB.2.3 sub-lineages and their latest spawns.
W...
COVID-19 News - SARS-Cov-2 - Cell Nucleus Apr 15, 2023 2 years ago
COVID-19 News: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has caused significant morbidity and mortality worldwide. In addition to acute infection, long-term complications, known as Long COVID or Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), have become a major concern. The cytopathic effects of SARS...
COVID-19 News - Irritable Bowel Syndrome (IBS) Apr 15, 2023 2 years ago
COVID-19 News: A groundbreaking meta-analysis by researchers from the University of Bologna-Italy has revealed that COVID-19 survivors are at a significantly higher risk of developing irritable bowel syndrome (IBS) compared to those who have never contracted the virus. With over 647 million confirmed cases of COVID-19 worldwide, the long-term consequences of the virus are becoming a mounting conce...
COVID-19 News - Hearing Loss Apr 15, 2023 2 years ago
COVID-19 News: A nurse's personal battle with COVID-19 related hearing loss has sparked alarms on a little-known side effect and has prompted further research into this COVID-19 effect that seems to be growing in terms of reported cases.
Kim Gibson, a nursing lecturer at the University of South Australia and registered nurse with a clinical background in neonatal intensive care, never...
COVID-19 News - Deficient Phagocytosis In Monocytes Apr 14, 2023 2 years ago
COVID-19 News : The SARS-CoV-2 pandemic has highlighted the vulnerability of the human immune system to opportunistic infections, especially among those with severe illness. One such opportunistic infection is mucormycosis, a life-threatening fungal infection that has been increasingly reported in COVID-19 patients, particularly in India as covered in numerous past COVID-19 News articles. The...
Long COVID - Autoantibodies Production Enhanced Even In Mild COVID-19 Apr 14, 2023 2 years ago
Long COVID: New study findings are raising alarm bells as scientists have discovered that even mild cases of COVID-19 can lead to long-term autoimmune issues in patients, whether they suffer from long COVID or not. Furthermore, vaccination doesn't seem to help in reducing autoantibody levels in these individuals. These discoveries call for an urgent reassessment of vaccination and infection pr...
COVID-19 News - SARS-CoV-2 - Acute Necrotizing Encephalopathy Apr 14, 2023 2 years ago
COVID-19 News: Once considered rare in the beginning of the COVID-19 pandemic, more cases studies of acute necrotizing encephalopathy are emerging globally with a new trend showing that its now mostly young adults or infants developing the condition!
Acute necrotizing encephalopathy (ANE) was first described in 1995 as a complication of viral respiratory tract infection in pediatric patie...
Medical News - T Cells - Extracellular Vesicles Apr 14, 2023 2 years ago
Medical News: A recent study led by Professor Dr Thomas Brocker and Dr Jan Kranich from LMU's Biomedical Center-Germany has demonstrated the significant role of extracellular vesicles (EVs) in enhancing the immune response of T cells, a crucial component of the immune system responsible for defending against viral infections. The study utilized a mouse model to explore the interaction between ...
COVID-19 News: I still cannot phantom how in this modern and technologically advanced age we can let entities like the WHO, the U.S. CDC, US.NIH, various elected politicians and government leaders around the world (many with no medical backgrounds!) and also the so-called medical experts whose daily advice is to simply get vaccinated or get a booster,….simply control all the COVID-19 narrat...
COVID-19 News - SLC6A20 Gene Apr 13, 2023 2 years ago
COVID-19 News: Since the beginning of the COVID-19 pandemic, researchers have been trying to understand the factors that increase the risk of severe illness and death. One of the areas that has drawn significant attention is the increased vulnerability of cancer patients to COVID-19. The SLC6A20 gene, found on chromosome 3p31.21, has been identified as a key causal gene associated with the severit...
COVID-19 News - India Records Highest COVID-19 Cases in Over 7 Months Apr 12, 2023 2 years ago
COVID-19 News: India has registered 7,830 new COVID-19 cases within the last 24 hours, the highest single-day rise in 223 days, raising the active case count to 40,215. The country recorded a single-day jump of 7,946 COVID-19 cases on September 1 last year.
The COVID-19 death toll has increased to 531,016, with 16 new fatalities reported in the last 24 hours, two each in Delhi, Punjab and...
COVID-19 News - Australia - Bad Onslaught Coming Apr 12, 2023 2 years ago
COVID-19 News: The Easter long weekend has come and gone, but Australia is reeling from the aftershocks of family gatherings and increased travel. With COVID-19 cases surging across the nation, health experts are warning that this could be the beginning of a disastrous new wave of infections, hospitalizations, and deaths. The state of Victoria alone has seen an alarming 60% increase in cases in ju...
COVID-19 News- ORF3A - Clic-Like Chloride Channel-1 (CLCC1) Apr 11, 2023 2 years ago
COVID-19 News: The ongoing battle against COVID-19 has led scientists to explore various aspects of SARS-CoV-2, the virus responsible for the disease. A deeper understanding of the interactions between the virus and the host's cellular machinery may provide novel therapeutic targets to mitigate the global impact of this pandemic.
While much attention including studies and COVID-19 New...
COVID-19 News - Dysnatremia Apr 11, 2023 2 years ago
COVID-19 News: In the relentless battle against COVID-19, a frequently overlooked but essential aspect of patient care is sodium imbalance. As one of the most common electrolyte disturbances in medical practice, dysnatremia, encompassing both hyponatremia and hypernatremia, has a profound impact on patient outcomes. In this in-depth analysis of the COLOS study, Polish researchers from Wroclaw Medi...
COVID-19 News - SARS-CoV-2 - Endoplasmic Reticulum Apr 10, 2023 2 years ago
COVID-19 News: The endoplasmic reticulum (ER) is a complex, interconnected network of channels and flattened sacs that plays a pivotal role in various cellular functions, including protein synthesis, folding, transport, and the regulation of intracellular calcium (Ca2+) levels. The ER has been identified as a critical player in the replicative cycle of SARS-CoV-2, the virus responsible for COVID-1...
COVID-19 News - IL-10 Linked to Thrombotic Complications In COVID-19 Apr 10, 2023 2 years ago
COVID-19 News: As the world continues to grapple with the ongoing COVID-19 pandemic, the scientific community has been working tirelessly to better understand theSARS-CoV-2 virus and its effects on patients. One area of significant interest is the role of cytokines i.e. small proteins secreted by cells that have a specific effect on the interactions between cells, in the development of throm...
COVID-19 News - Japan's New XBB Surge Apr 10, 2023 2 years ago
COVID-19 News: For the first time in two and a half months, Japan is witnessing a concerning rise in COVID-19 cases. According to the health ministry, during the week ending April 4, the number of new infections increased by 1.03 times from the previous week. This surge was observed in 18 out of Japan's 47 prefectures, with the most significant increases in Fukui, Hokkaido, Akita, Tokyo, and I...
COVID-19 News - 5-Aminolevulinic Acid (ALA) Apr 09, 2023 2 years ago
COVID-19 News: As the world continues to grapple with the COVID-19 pandemic, a natural amino acid, 5-aminolevulinic acid (ALA), is emerging as a potential antiviral for SARS-CoV-2 infections. This groundbreaking discovery could pave the way for an innovative treatment strategy that targets the angiotensin-converting enzyme 2 (ACE2) receptor, which plays a critical role in the virus's ability t...
COVID-19 News - XBB Sublineages In India Apr 09, 2023 2 years ago
Indian scientists discovered new mutations like A27S and T747I along with mutations like T981S, I1998V, T323I, 306 G252V, A653V on circulating and emerging XBB sub-lineages in India with clinical evaluations confirming that multiple booster doses or a history of SARS-CoV-2 previous infection in the pre-Omicron era did not protect from these currently circulating recombinant sub-lineages and diseas...
Long COVID - SARS-CoV-2 - Mitochondria Apr 09, 2023 2 years ago
Long COVID: Mitochondria, the cellular powerhouses, are crucial for cellular energy production and homeostasis. They form dynamic networks within cells, adapting their morphology to meet fluctuating energy demands. Interestingly, the mitochondrial network is vulnerable to perturbations in its dynamics and function due to interactions between SARS-CoV-2 proteins and certain mitochondrial proteins. ...
COVID-19 News - Celiac Disease Apr 09, 2023 2 years ago
COVID-19 News: The ongoing COVID-19 pandemic has left numerous people grappling with persistent post-COVID-19 symptoms, collectively known as long COVID.
Previous research and COVID-19 News coverages have shown that COVID-19 shares immunological traits with autoimmune diseases, including overactivity of certain immune cells. This has led to growing evidence linking COVID-19 with the devel...
COVID1-9 News - SARS-CoV-2 Infections Causes Gut Immunological Barrier Dysfunction Apr 08, 2023 2 years ago
COVID-19 News: A new study by researchers from Medical School, University of Patras-Greece, University Hospital of Patras-Greece and Patras State General Hospital-Greece has found that SARS-CoV-2 infections often lead to the dysfunction of the gut’s immunological barrier.
Key features of intestinal immune barrier disruption during SARS-CoV-2 infection. SARS-CoV-2 infection is associated wi...
COVID-19 News: Picture this: a massive crowd of people shouting in unison, “WE ARE ALL INDIVIDUALS!” Suddenly, a lone voice from the crowd sheepishly mutters, “I’m not.” This famous scene from the Monty Python comedy troupe brings to light the concept of immunodominant public antibody responses, an immune system phenomenon that could make us vulnerable to viral reinfe...
COVID-19 News - HERV-W Envelope Protein Apr 07, 2023 2 years ago
COVID-19 News: The COVID-19 disease caused by the SARS-CoV-2 coronavirus, leads to diverse symptoms and syndromes in patients, from benign to severe forms. The dysregulation of innate and adaptive immunity plays a critical role in the clinical outcome of COVID-19 patients, driving severe evolution of the disease.
A new international study investigated whether SARS-CoV-2 could activate end...
Editorial: Even as the world continues to grapple with the aftermath of the COVID-19 pandemic, a more sinister and dangerous threat is looming on the horizon. The increased reliance on biotechnology, coupled with the controversial practice of gain-of-function research, has created a potential breeding ground for a new and potentially deadlier pandemic.
This editorial explores the imminent...
Long COVID- Fasudil - Rho-Kinase Inhibitor - SARS-CoV-2 Induced Vascular Dysfunction Apr 07, 2023 2 years ago
Long COVID: The world is grappling with the long-term consequences of COVID-19, and millions of patients continue to experience debilitating symptoms long after the acute phase of the disease. This phenomenon, known as Long COVID, affects a significant portion of the population, with systemic vascular dysfunction being a key component.
Despite the widespread prevalence of Long COVID, the ...
COVID-19 Drugs - Methotrexate, Pralatrexate, Trimetrexate Apr 07, 2023 2 years ago
COVID-19 Drugs: Since the outbreak of the COVID-19 pandemic, the scientific community has been tirelessly working to find effective therapeutic strategies to treat SARS-CoV-2-induced respiratory disease. Repurposing approved drugs has emerged as the most rapid, affordable, and efficient strategy for addressing this urgent need. Among the drugs tested for repurposing, methotrexate (MTX), a widely u...
COVID-19 News - India -5335 New Cases In Last 24 Hours Apr 06, 2023 2 years ago
COVID-19 News: More Great News! According to official reports from Indian health authorities, there were more than 5,335 new COVID-19 infections in the last 24 hours. Considering that India has a population of more than 1.4 billion people and that in most crowded cities there is very little precautions being undertaken coupled with the fact there is very little testing and India’s notoriety ...
COVID-19 News - CD147 - Cyclophilin A - Cancer Apr 06, 2023 2 years ago
COVID-19 News: Iranian researchers from Qazvin University of Medical Sciences, Lorestan University of Medical Sciences, Shiraz University of Medical Sciences, University of Tehran and Tehran University of Medical Sciences are claiming that CD147 And Cyclophilin A (CyPA) play key roles in COVID-19 severity, cancer progression and chemotherapy resistance in cancer patients with COVID-19.
The ...
Long COVID - Sleep Issues Apr 06, 2023 2 years ago
Long COVID, or post-acute sequelae of COVID-19 (PASC), is a global public health crisis marked by patients experiencing lingering and debilitating symptoms beyond four weeks after the acute onset of SARS-CoV-2 infection.
Pic Credit: ThinkStock Photos
Sleep disturbances are prevalent in 34-50% of Long COVID cases, but the severity, associated risk factors, and interactions with mood disord...
COVID-19 News - Endogenous piRNAs Apr 05, 2023 2 years ago
COVID-19 News: In an astounding revelation, a groundbreaking study by researchers from the Polish Academy of Sciences and A. Baitursynov Kostanay Regional University in Kazakhstan has identified a potential game-changer in the battle against the relentless SARS-CoV-2 Omicron variant.
Although the research is still in its preliminary, in silico phase, the astonishing findings are impossibl...
COVID-19 News - Surfactant Protein A - (SP-A) - Antiviral Apr 05, 2023 2 years ago
COVID-19 News: In a groundbreaking study, scientists have found that a human protein called Surfactant Protein A (SP-A) can inhibit the infectivity of SARS-CoV-2, the virus responsible for COVID-19, in human lung epithelial cells. This remarkable discovery sheds light on the potential of SP-A to be used as a biomarker for COVID-19 severity and a potential therapeutic component.
The study ...
Infertility - WHO - COVID-19 - SARS-CoV-2 Apr 04, 2023 2 years ago
The World Health Organization (WHO) has recently reported that one in six people worldwide, or approximately 17.5% of the adult population, are affected by infertility. This alarming statistic has prompted the UN health agency to call for cheaper and more accessible fertility treatments.
https://www.who.int/news/item/04-04-2023-1-in-6-people-globally-affected-by-infertility
With the ongoi...
SARS-CoV-2 Research - Spike protein - Memory Loss Apr 04, 2023 2 years ago
Individuals diagnosed with post-COVID-19 syndrome frequently experience cognitive and memory issues. A new study from researchers from the Federal University of Rio de Janeiro (UFRJ)-Brazil and Rio de Janeiro State University (UniRio)-Brazil sheds light on the mechanism behind these problems.
The study found that the Spike protein, which enables the virus to enter human cells, could be responsib...
COVID-19 News - Vascular Complications of COVID-19 Apr 04, 2023 2 years ago
The ongoing COVID-19 pandemic has posed numerous challenges to the global healthcare system. While respiratory symptoms have been the most prominent manifestation of the disease, an increasing number of vascular complications have been identified. A review published in the Canadian Journal of Cardiology, titled "An evolving understanding of the basis and management of vascular complications o...
COVID-19 News: Since its emergence in late 2019, the SARS-CoV-2 virus has continued to evolve and adapt. As the virus responsible for COVID-19, researchers have extensively investigated its replication and pathogenesis to develop vaccines and treatments. The viral spike protein has been the main focus due to its role in infection and transmission. However, other viral proteins have been less studi...
COVID-19 News - Tetraspanin-8-TSPAN8-Mediator-SARS-CoV-2-Infections Apr 02, 2023 2 years ago
A new study by researchers from the University of California, San Francisco - USA has found that the human protein that Tetraspanin-8 (TSPAN8) is a mediator in in SARS-CoV-2 infections.
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these...
COVID-19 News - SARS-CoV-2 Spike Protein Induces Endothelial Cell Permeability Apr 02, 2023 2 years ago
COVID-19 News: A news study by researchers from the Institute of Life Science, School of Medicine, Swansea University - UK has found that the SARS-CoV-2 spike protein induces endothelial cell permeability and von Willebrand Factor secretion.
COVID-19, caused by the SARS-CoV-2 virus, has become a global pandemic with devastating effects on public health and economies worldwide. While prima...
COVID-19 News - Australia - XBB.1.16 - XBC.1.6 Apr 02, 2023 2 years ago
COVID-19 News: The COVID-19 situation in Australia continues to escalate as the nation records its seventh-straight week of increased cases. With 26,531 new confirmed cases and 90 deaths reported this week, authorities are urging Australians to receive their booster doses as soon as possible. Hospitalizations have risen to 1,508, but the number of people in intensive care has slightly dropped to 3...
Philippines - Philippines Apr 01, 2023 2 years ago
COVID-19 News: In the last few hours, the Philippines Department of Health (DOH) reported that the country saw 330 additional COVID-19 cases in the last 24 hours.
According, the new SARS-CoV-2 infections brought the number of active infections nationwide to 9,021, as shown in the DOH's Covid-19 tracker.
https://doh.gov.ph/covid19tracker
It was reported that Metro Manila remaine...
Long COVID - Hyperbaric Oxygen Therapy (HBOT) Apr 01, 2023 2 years ago
Long COVID: A growing number of peer reviewed studies are showing that Hyperbaric Oxygen Therapy (HBOT) might be useful in Long COVID. Certain cases studies and clinical trials have showed its effectiveness in helping with manifestations of fatigue, various cognitive and neurological issues in Long COVID.
Hyperbaric oxygen therapy or HBOT involves breathing pure oxygen in a pressurized en...
XBB.1.16: The technical lead for the COVID-19 response at the World Health Organization (WHO), Maria Van Kerkhovee has warned that more attention should be focused on the new SARS-CoV-2 recombinant sub-lineage XBB.1.16 as its starts its ravage in various geolocations across the world.
https://twitter.com/mvankerkhove/status/1641489462461968414
Already preliminary data is showing that...
COVID-19 News - Giant Cell Arteritis Apr 01, 2023 2 years ago
It is becoming more apparent each passing day that exposure to the SARS-CoV-2 coronavirus can trigger a whole avalanche of medical conditions, health issues and diseases as the novel coronavirus is able to cause disruption and damage to hundreds of the human host cellular pathways, genes, key enzymes and proteases and also cause damage to various cells and tissues.
Adding the list of nume...
COVID-19 News - Host miRNAs Contribute To Evolution Of SARS-CoV-2 Apr 01, 2023 2 years ago
COVID-19 News: The positive-sense RNA genome of the SARS-CoV-2 virus, responsible for the COVID-19 pandemic, is approximately 30,000 nucleotides in length. Since its emergence in December 2019 with the WuhanHu-1 strain, over 10,000 recorded nucleotide mutations have been documented, with an estimated mutation rate ranging from 0.0004 to 0.002 mutations per nucleotide per year.
Pic Credit:C...
COVID-19 News - Interleukin 27 Apr 01, 2023 2 years ago
A new study by researchers from Universidad de Antioquia-Colombia has found that Interleukin 27 plays an important role in COVID-19 pathogenesis and inflammation regulation.
Interleukin 27 (IL27)
Interleukin 27 (IL27) is a heterodimeric cytokine, member of the IL6/IL12 family of cytokines, composed of IL27p28 and Epstein-Barr virus-induced 3 (EBI3) subunits.
Importantly, its intera...
COVID-19 News - SARS-CoV-2 Altered Blood-Brain Barrier - Drug Transport Apr 01, 2023 2 years ago
COVID-19 News: A new study by Mexican medical scientists has found that SARS-CoV-2 virus is able to alter the Blood-Brain Barrier of the human host with concerning implications as many of the drugs used during treatment can also thereafter gain access to the brain when in the first place, during development and research, they were made knowing very well that their active molecules would never be a...