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Source: COVID-19 Antivirals Feb 04, 2021 4 years ago
COVID-19 Antivirals: Japanese researchers from National Institute of Infectious Diseases, Tokyo and the Tokyo University of Science have in a new study found that oxidized cholesterol derivatives or oxysterol exhibits potent antiviral activity against the SARS-Cov-2 coronavirus.
Developments of effective antiviral drugs targeting SARS-CoV-2 are urgently needed to combat the COVID-19 disea...
Source: COVID-19 Mutations Feb 03, 2021 4 years ago
COVID-19 Mutations: Authorities from Public Health England have reported alarming discovery this week: The B.1.1.7 variant that has brought that country to its knees appears to be further mutating to gain a mutation that could help it elude vaccines. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/957504/Variant_of_
Concern_VOC_202012_01_Technical_Br...
Source: COVID-19 Treatments Feb 03, 2021 4 years ago
COVID-19 Treatments: A new study by researchers from National Taiwan University Hospital and National Taiwan University College of Medicine has found that zinc supplementation enhances the efficacy of certain repurposed drugs such as triclabendazole and emetine.
The SARS-CoV-2 has caused vast number of infections and fatalities worldwide with almost 104 million infections and more than 2.25 milli...
Cannabis News: A new research led by scientist from the University of Queensland has found that synthetic cannabidiol, better known as CBD is able to kill bacteria that cause gonorrhea, meningitis and legionnaires disease.
The study findings could lead to the first new class of antibiotics for resistant bacteria in 60 years.
At present antimicrobial resistance threatens the viabili...
COVID-19 News: Globally a new phenomenon is being witnessed in which those that never had a history of diabetes before but upon being infected with the new SARS-CoV-2 coronavirus are experiencing a sudden elevation of blood sugar levels and in some cases are ending up with full blown diabetes weeks after so called ‘COVID-19 recovery.’ https://www.thailandmedical.news/news/breaking-covi...
Source: COVID-19 Clinical Care Feb 02, 2021 4 years ago
COVID-19 Clinical Care: A new study by researchers from the Department of Internal Medicine, University of Michigan, Ann Arbor-USA has discovered that a sub-group of COVID-19 patients exhibit high bleeding risk contradicting an initial advocated protocol of administering high dose anticoagulants throughout the duration of their disease course.
From the study abstract, “Typically pat...
COVID-19 Herbs: Scientists from King Fahd Medical Research Center at King Abdulaziz University in a new study have demonstrated the antiviral effects of two medicinal herbs: Hypericum perforatum also called St. John's Wort and Echinacea or Purple Cone Flower against the SARS-CoV-2 coronavirus, the pathogen that causes COVID-19.the study showed that each herb as well as the two combined, e...
Cancer News: A new study by researchers from John Hopkins’ Kimmel Cancer Center shows that frequency of oral sex along with number of sex partners one has are all contributing factors to increasing one’s risk of developing propharyngeal cancer.
The study showed that a wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated hea...
Vaccine News: We at Thailand medical News are typically skeptical about all the various COVID-19 vaccines being promoted currently due to the fact that many were developed in such a rush, bypassing standard testing and procedures, lack of transparency coupled with the fact that the past track record of coronavirus vaccines have not been very successful, often causing more problems for the te...
COVID-19 Drugs: A new study by researchers from University of Montreal-Canada,New York University-USA, Universidad Autónoma de Madrid-Spain, Universidade de São Paulo-Brazil, Mayo Clinic-USA, San Francisco General Hospital-USA, Cedars-Sinai Heart Institute-USA And Université Laval-Canada has found that the existing anti-inflammatory oral drug drug-Colchicine could be rep...
COVID-19 Drugs: Researchers from Emerging Pathogens Institute at Icahn School of Medicine at Mount Sinai and University of California-San Francisco’s Quantitative Bioscience Institute (QBI) have in a new study found a exsiting cancer drug called Aplidin effective against the SARS-CoV-2 coronavirus including the newly emergent B.1.1.7 variant.
The cancer drug Aplidin is mad...
Source: COVID-19 Antivirals Jan 31, 2021 4 years ago
COVID-19 Antivirals: A new international research involving scientist from Universidad Católica de Valencia-Spain, Kyoto University-Japan, University of Vienna-Austria, Pingla Thana Mahavidyalaya-India, Indian Statistical Institute-India, University of South Florida-USA, University of Otago-New Zealand, University of Padova-Italy, Yarmouk University-Jordan, CSIR-Indian Institute of Chemical...
Coronavirus News: A new study by researchers from the University of Belize and National Sun Yat-Sen University-Taiwan have discovered that the SARS-CoV-2 coronavirus is able to resists extreme variations in temperature and compared to initial studies done in the beginning of the pandemic, the new findings show that temperature changes between the winter and summer months have a negligible effect o...
Source: Vitamins, Steroids and Retinoids For COVID-19 Jan 30, 2021 4 years ago
Vitamins, steroids and retinoids can be used as adjuvants to treat COVID-19 according to a new study by scientists from the University of Bristol.
According to the study abstract, “The study team investigated the binding of linoleate and other potential ligands to the recently discovered fatty acid binding site in the SARS-CoV-2 spike protein by using docking and molecular dynamics ...
Source: SARS-CoV-2 Variants Jan 29, 2021 4 years ago
A new study led by scientists from Columbia University shows warning signs that recently emerged SARS-CoV-2 variants such as the B.1.1.7, B.1.351, and B.1.1.28 variants have become worryingly resistant to monoclonal antibody therapies, plasma from convalescent patients and sera from vaccinated individuals.
This new study findings contradict earlier studies the last few days published by cer...
COVID-19 Drugs. While America and the United Kingdom along their so called ‘experts’ and corrupted politicians are constantly denouncing generic drugs that can be repurposed to treat COVID-19, supplements and herbs that can be used as adjuvants to also treat SARS-CoV-2 infections, more countries overseas are now beginning to accept ivermectin for use as both a prophylaxis and also as a...
Source: COVID-19 Vaccine Contest Jan 28, 2021 4 years ago
COVID-19 Contest: In a spirit of getting more involvement from our readers, we are organizing a simple contest for all our readers around the world, simply read the recently published preprint study by researchers from Moderna and the US NIH and tell us the flaws and hidden facts from the study claiming that its vaccines work on the new SARS-CoV-2 variants.
The preprint study can be found...
Research News: A new international study led by scientists from Francis Crick Institute involving numerous other research institutions has revealed that the SARS-CoV-2 coronavirus interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.
According to the study abstract, “The coronaviral spike is the dominant viral ant...
Source: COVID-19 Innovations Jan 27, 2021 4 years ago
COVID-19 Innovations: A new U.S.NIH-funded study led by researchers from Division of Biology and Biological Engineering, California Institute of Technology (Caltech) shows the potential of a remarkably adaptable, nanoparticle-based approach to coronavirus vaccine development.
A new coronavirus vaccine approach works by attaching many spike protein receptor-binding domains
(RBDs) to an engineered...
Vaccine News: Media outlets are abuzz in the last 24 hours about a warning letter sent to the US FDA and Pfizer by a leading immunologist cum scientist in Pennslyvania, Dr Hooman Noorchashm.
The letter warns about the immunological danger of COVID-19 Vaccination in recently convalescent and asymptomatic carriers most especially to those who are elderly, frail or have significant car...
Source: COVID-19 Research Jan 27, 2021 4 years ago
COVID-19 Research: Scientists from Erasmus Medical Center-Netherlands and the University of Illinois at Urbana-Champaign-USA have found that the SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation that is often used in in vitro studies, hence not proper representing the actual viral life cycle as would be in a typical human host setting and can sometimes also lead to misleading laborator...
Source: Prostate Cancer News Jan 26, 2021 4 years ago
Prostate Cancer News: Researchers from the the Korea Institute of Science and Technology (KIST) and the University of Ulsan College of Medicine,-Seoul have developed a new urine based diagnostic platform that far more faster and accurate to detect prostate cancer.
Currently screening for prostate cancer relies on the serum prostate-specific antigen test, which provides a high rate of fals...
Source: COVID-19 Treatments Jan 26, 2021 4 years ago
COVID-19 Treatments: A new meta study by researchers from University of Bari "Aldo Moro", Policlinico University Hospital of Bari-Italy, A. Xhuvani University of Elbasan-Albania and Riuniti University Hospital of Foggia-Italy have shown that probiotics play a vital role in the immune system and helps COVID-19 patients to recover faster leading to its possible role as adjuvants in C...
Vaccine News: A new study by researchers from University of East Anglia, Norwich-UK led by Professor Dr Alastair Grant and Professor Dr Paul R Hunter indicates that the current COVID-19 vaccines will not be able to attain herd immunity against the SARS-CoV-2 coronavirus.
While the COVID-19 pandemic continues to claim thousands of lives each day and cause severe disruptions to ordinary lif...
Source: U.S. Medical News Jan 25, 2021 4 years ago
U.S. Medical News: The United States, the country with the most so called ‘experts’ who spend half of their time on twitter (No one really know if they truly work or really have jobs or are just some unknown individual in real life that do not really matter in the course of things!), ‘fact checkers’ (mostly garbage with no medical trainings) and tech giants that are control...
Source: COVID-19 Questions Jan 25, 2021 4 years ago
COVID-19 Questions: Am interesting query that is currently on the minds of many with brains and intelligence (Less than 5 per cent of the global population and less than 0.01 of Thailand’s population) is whether or not individuals receiving an mRNA-based vaccine against SARS-CoV-2 will experience changes in their DNA in cells “infected” by the encapsulated mRNA.
Already ...
COVID-19 Drugs: Researchers from the University of Bari Aldo Moro-Italy and the University Campus Bio-Medico of Rome have in a new study found that the diuretic drug Ethacrynic Acid could be repurposed to treat COVID-19.
The research findings are published in the peer reviewed journal: Viruses https://www.mdpi.com/1999-4915/13/1/106/htm
The SARS-CoV-2 coronavirus, the causative ...
Source: COVID-19 Research Jan 24, 2021 4 years ago
COVID-19 Research: A new study by researchers from the Division of Cardiovascular Medicine, Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital has found that blood groups are associated with cardiovascular events in COVID-19 patients. In particular blood groups A and AB were associated with higher risks of Major Adverse Cardiovascular Events (MACE).
F...
Source: COVID-19 Immunology Jan 24, 2021 4 years ago
COVID-19 Immunology: Another study, this time by scientists from the University of Texas have found that SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues.
IFN-I is a key component of host innate immunity that is responsible for elim...
COVID-19 News: Things are going to change to a certain degree with President Biden now in power. It is no surprise that even the American infection figures, death rates and vaccine efficacy might falsely start to appear as getting better after all Biden was heavily backed by the various pharmaceutical giants’ money during the recent elections. https://www.drugdiscoverytrends.com/guess-who-th...
Coronavirus News: Researchers from University College London-UK, University of Amsterdam-Netherlands, King's College London-UK, the Francis Crick Institute-UK and University of Cambridge-UK in a new study have demonstrated that the neutralizing activity of monoclonal antibodies can be dramatically reduced by mutations of the SARS-CoV-2 spike glycoproteins unlike polyclonal antibodies generated...
Source: COVID-19 Research Jan 23, 2021 4 years ago
COVID-19 Research: A new study by researchers from the University of Illinois at Chicago shows that the nonstructural proteins of the SARS-CoV-2 coronavirus dysregulates the immune responses and cell signaling of the human host to generate a permissive environment.
According to the study team, the SARS-CoV-2 proteins upregulate or downregulate more than 100 human kinases involved in cellu...
Vaccine News: A new research by scientists from Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID)-University of Cambridge, University College London, University of Kent and Addenbrookes Hospital-UK shows that the Pfizer-BioNTech vaccine exhibits reduced neutralization potential against SARS-CoV-2 B.1.1.7 variant.
The new study findings contradicts Pfizer&rsqu...
Source: Viral Persistence Jan 22, 2021 4 years ago
Viral Persistence: A new research by scientists from the Georgia State University involving animal models has demonstrated that mice being infected with the SARS-Cov-2 coronavirus through their nasal passages developed severe illness due to brain infection even after the virus had left their lungs. The implications of the study findings suggest viral persistence in individuals despite testing nega...
Source: SARS-CoV-2 Variants Jan 22, 2021 4 years ago
SARS-CoV-2 Variants: Eachtime the SARS-CoV-2 coronavirus replicates, it has a chance to mutate. And given that it is currently rampaging around the world, it has plenty of opportunities to do just that.
Typically most of these mutations will make little or no difference to the virus's ability to spread or cause more severe disease. Others will make it less likely to spread ie those mu...
Research News: A new study by researchers from Washington University School of Medicine- St. Louis has found that individuals with Barrett’s Esophagus have increase susceptibility to COVID-19 disease.
Barrett’s esophagus is a condition in which the lining of the esophagus changes, becoming more like the lining of the small intestine rather than the esophagus. This occurs in th...
Source: SARS-CoV-2 origins Jan 21, 2021 4 years ago
Taiwan News staff writer Keoni Everington has written a piece with regards to a World Health Organization inspector being recorded on video discussing the testing of modified coronaviruses on human cells and humanized mice in the Wuhan Institute of Virology (WIV), just weeks before the first cases of COVID-19 were announced in the city of Wuhan itself.
Dr Vincent Racaniello (left) Dr Peter...
Source: SARS-CoV-2 Mutations Jan 21, 2021 4 years ago
SARS-CoV-2 Mutations: While certain vaccine manufacturers are releasing studies by their own staff claiming that their vaccines will still likely to work on the various emerging SARS-CoV-2 variants and many so called ‘credible’ American media are also publishing articles promoting this misinformation, South African researchers in a news study have confirmed that the 501Y.V2 variant esc...
N501Y Mutation: Scientist from University of Oxford in a news study have found that the N501Y mutation found on the SARS-CoV-2 B.1.17 variant possibly causes a higher viral load in those infected with the variant.
The B.1.1.7 variant also called VUI-202012/01 has emerged which is increasing in frequency, primarily in the South East of England
One potential hypothesis is that infect...
Source: Ivermectin-COVID-19 Jan 20, 2021 4 years ago
Ivermectin-COVID-19: While there are more than 50 studies currently expounding the efficacy of Ivermectin to treat COVID-19 and also as a prophylaxis against the COVID-19 disease, it usage should be carefully monitored and it should always be used under the supervision of a medical doctor or with proper dosing spelt out.
https://c19ivermectin.com/
The drug has yet to be officially approve...
Coronavirus News: As the SARS-CoV-2 continues to evolve and mutate to enhance its own survival despite therapeutic interventions such as convalescent plasma, monoclonal and combination monoclonal protocols, vaccines etc, more variants are fast emerging to counter all mankind’s initiatives and its imperative for researchers to identify all possible mutations that appear on the new variants th...
COVID-19 News: Scientist from the University of Southern California have discovered that the SARS-CoV-2 coronavirus typically ‘attacks’ the mitochondria in the cells of the human host. The resulting disruptions in the ‘power house’ of the cells could be one reason many COVID-19 patients and also post COVID patients often suffer from chronic fatigue.
In their study ab...
Source: SARS-CoV-2-Variant-News Jan 19, 2021 4 years ago
SARS-CoV-2 Variant News: A new lesser-known variant known as the L452R variant had been circulating in the Los Angeles county in the last few weeks according to Public Health Department.
The newly announced variant was first identified in Denmark in March 2020. It showed up in California as early as May.
Professor Dr Charles Chiu, a virologist and professor of laboratory medic...
Source: SARS-CoV-2 Variants Jan 18, 2021 4 years ago
SARS-CoV-2 Variants: A team from Southern Illinois University Carbondale traced the earliest appearance of new variant, called 20C-US, to Texas in May 2020. Scientists say the variant has not spread significantly beyond the country's borders, and that is most highly prevalent in the Upper Midwest.
However this third variant could be responsible for at lea...
COVID-19 News: Scientists from California based biotech company, Immunity Bio Inc have in a new study found that the combination Of E484K, K417N and N501Y mutations found in various new emerging SARS-CoV-2 variants can lead to immune evasion and reinfections even in those with previous immunity. The study findings also indicate that all the current COVID-19 vaccines would most probably be ine...
Coronavirus News: Chinese health authorities reported that active and infectious forms of the SARS-CoV-2 coronavirus were found on ice cream produced in the eastern city of Tianjin, prompting a recall of cartons from the same batch.
The ice cream manufacturer, Daqiaodao Food Co., Ltd. in Tianjin, adjacent to Beijing, was sealed and its employees were being tested for the SARS-CoV-2 corona...
COVID-19 News: Scientist are concerned over the new SARS-CoV-2 variant that emerged in Manaus, Brazil called P.1 that has more mutations on it than even the UK variant called B.1.1.7 or even the South African Variant called B.1.351 as it could change the course of the current pandemic if it starts becoming prevalent.
The new P.1 variant lineage carries 17 unique amino acid changes, 3 dele...
HIV News: A new international study led by the University of Southern California, involving various other research entities including University of Cape Town-South Africa,Thai Red Cross AIDS Research Centre-Thailand, University of Amsterdam-Netherlands, Washington University School of Medicine-USA, Missouri University of Novi Sad-Serbia ,University of New South Wales-Australia, University of Calif...
COVID-19 Drugs: Researchers from the University of Alabama at Birmingham have found in a new study that metformin usage among patients with type 2 diabetes had decreased mortality rates when contracting the COVID-19 disease.
The COVID-19 disease is a growing pandemic with an increasing death toll that has been linked to various comorbidities as well as racial disparity. However, the specific char...
Source: COVID-19 Research Jan 16, 2021 4 years ago
COVID-19 Research: Scientist from the University of Salento-Italy and the University of Paris-France in a new study have found that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the SARS-CoV-2 virus strain and that of the human host.
Variants of SARS-CoV-2 have been identified rapidly after the beginning of the COVID-19 pandemic. O...
Vaccine News: A new breaking development has emerged with a total of 23 deaths being reported by the Norwegian Medicines Agency in connection with the Pfizer’s /BioNTech vaccines. To date 13 of these cases have been assessed so far and confirmed as linked to the vaccines.
https://legemiddelverket.no/nyheter/meldte-bivirkninger-etter-koronavaksine-pr-14-januar-2021
Norway Reports 23 ...
Source: Coronavirus Latest Jan 15, 2021 4 years ago
Coronavirus Latest: Scientists from Brazil in a new study led by the University of Sao Paulo and involving numerous other research institutions have found that oxidative stress and neurotoxicity biomarkers increased in tadpoles exposed to synthetic SARS-CoV-2 spike protein peptides.
Aquatic animlas like prawns, not only tadpoles could be affected
by the SARS-CoV-2 coronavirus. Image Cr...
COVID-19 Drugs: A new study by researchers from University of Birmingham-UK, Keele University-UK, San Raffaele Scientific Institute-Italy, University of Copenhagen-Denmark and the University of Liverpool-UK demonstrates that the drug called Fenofibrate exhibits antiviral properties against the SARS-CoV- coronavirus and could be repurposed to treat COVID-19.
Fenofibrate, ...
COVID-19 News: Researchers from the Ohio State University Wexner Medical Center and College of Medicine have discovered a new variant of SARS-Cov-2, the virus that causes COVID-19 called the COH.20G/501Y variant.
The scientist are still in the process of deciphering all the various mutations found on the genome of this new variant but do admit that the new variant carries a...
Source: COVID-19 Research Jan 14, 2021 4 years ago
COVID-19 Research: Scientists from the Department of Molecular and Cell Biology, University of California-Berkeley have in a new study identified the SARS-CoV-2 ORF8 protein as being responsible for the rapidly evolving immune evasion characteristics of emerging strains and also responsible for the increasing pathogenicity of the coronavirus.
Crystal structure of SARS-CoV-2 ORF8. (A) A 2Fo-Fc el...