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Drugs News: A new study by researchers from the Universities of Edinburgh, Birmingham, Oxford and Nottingham have found the drug Gabapentin that is regularly used to treat chronic pelvic pain in women has been found to be no more effective than a placebo.
Chronic pelvic pain is estimated to affect 2–24% of women worldwide, and is associated with substantially reduced quality of life...
Pharma News: Pharma giant Roche has partnered with Regeneron Pharmaceuticals to develop, manufacture and distribute Regeneron’s antiviral antibody combination, REGN-COV2, as a potential treatment of COVID-19.
The new antibody combination REGN-COV2 could help treat patients with symptoms and also prevent the disease in individuals exposed to the SARS-CoV-2 coronavirus.
An init...
Source: COVID-19 Diagnostics Sep 25, 2020 4 years ago
COVID-19 Diagnostics: Immunology experts at the University of Birmingham-UK have developed a new COVID-19 test using dried blood spot samples (DBS) as an accurate alternative to venous blood in detecting SARS-CoV-2 antibodies.
DBS sampling is simple, inexpensive and can be self-collected by
the patient at home, using a simple finger prick.
Credit: University Of Birmingham
The research fin...
COVID-19 Reports: A study presented at the ongoing ESCMID Conference on Coronavirus Disease (ECCVID, 23-25 September) indicates that the severe COVID-19 immunological profile, represented by changes in cell populations and circulating inflammatory proteins, is already partly present in older healthy individuals in the West especially in Europe. (Applicable to Northern America as well)
The...
Source: COVID-19 Severity Sep 25, 2020 4 years ago
COVID-19 Severity according to yet another study, this time by researchers from Rockefeller University is also linked to mutations in human genes but this time in a group of 13 genes associated with antiviral defense. Mutations in any one or more of these genes can also increase disease severity in those infected with the SARS-CoV-2 coronavirus.
The study findings were published in the jo...
Source: Human Genetic Mutations PiZ And PiS Sep 25, 2020 4 years ago
Human Genetic Mutations PiZ And PiS found in segments of the general population contributes to a greater risk of severity and mortality from COVID-19 disease according to researchers from Tel Aviv University-Israel.
Accordingly these mutations lead to deficiency in the alpha1-antitrypsin protein, which protects lung tissues from damage in case of severe infections.
The study findin...
Source: Russia COVID-19 News Sep 24, 2020 4 years ago
Russia COVID-19 News: Russia proudly launched the world’s first COVID-19 vaccine Sputnik V despite lack of proper phase 3 trial data and was boasting about its mass vaccinations program that is currently under way. To top it up, only a few days ago it also announced that its local version of the teratogenic drug favipiravir which is called Coronavir is being made available at pharmacies acro...
Source: Coronavirus Warning Sep 24, 2020 4 years ago
Coronavirus Warning: Day by day it is emerging despite initial denials by researchers that the SARS-CoV-2 resembles an airborne version of the HIV virus that kills the human host slowly except for those that are vulnerable either due to age, a weakened immune system and the presence of various comorbidities, where the process is even faster.
A new study by Chinese researchers from Tongji ...
Pandemic News: Researchers from the Wayne State University-Detroit and the Detroit Medical Center in a new study that was presented at the ongoing online ESCMID Conference on Coronavirus Disease (ECCMID, online 23-25 September) showed that the initial SARS-CoV-2 viral load in nasopharyngeal samples has been decreasing as the pandemic progressed.
Interestingly the study team led by Dr Said...
Pterostilbene (PSB) a polyphenolic phytochemical that occurs in plants, particularly small berries and nuts has been identified by Japanese researchers from the Tokyo University of Science as a new therapeutic option for chronic inflammatory disorders.
The study findings are published in the FASEB Journal: (Journal of the Federation of American Societies for Experimental Biology) https://faseb.on...
News-COVID-19: Researchers from the University of California-San Diego (UCSD) in a new study found that a high percentage of recovered COVID-19 patients exhibited ocular inflammation in their eyes which is a type of neuroinflammation.
The study findings by the researchers from the Department of Ophthalmology-UCSD, the Division of Infectious Diseases and Global Public Health-UCSD, and the ...
Virus News: Researchers from the Swiss Federal Institute of Technology-Lausanne (EPFL) in a new study shows that pathogenic viruses may be able to develop resistance to warm temperatures and certain some types of disinfectant such as chlorine. That combined with global warming and more frequent and longer heat waves could make it even harder to keep them from spreading.
The study te...
COVID-19 Latest: Researchers from University of California-San Diego, University of Texas-Austin and Maynooth University-Dublin have discovered an active role for glycans, the sugar molecules that decorate the spike proteins of the coronavirus in terms of the actual infection and binding process to human host receptors.
These glycans in turn could be new targets for certai...
Source: COVID-19 Updates: Sep 24, 2020 4 years ago
COVID-19 Updates: Thursday morning starts with the global death toll reaching almost 974,000 due to the novel coronavirus that originated from Wuhan, China and whose global spread was never stopped by the WHO (World Health Organization) led by black Ethiopian national Tedros Adhanom Ghebreyesus who is still shamelessly refusing to resign from his position despite calls and online petitions.
&nbs...
Source: COVID-19 Treatments Sep 24, 2020 4 years ago
COVID-19 Treatments: Two new studies by researchers from the University of California-San Diego show that statin usage is linked to a lower risk of developing COVID-19 severity and that removing cholesterol from cell membranes prevents the virus from getting into these cells.
Furthermore there is some biologic plausibility for a protective role of statins in COVID-19 through known anti-in...
Source: COVID-19 Research Sep 23, 2020 4 years ago
COVID-19 Research: Good news for most of the mental asylums as most of their inmates are less likely to suffer from the COVID-19 severity due to the fact that they are likely to possess a mutated variant of the human gene Rs4702 according a new vitro study from Icahn School of medicine that shows how human genes affects the COVID-19 disease besides numerous other factors and comorbidities.
 ...
Source: COVID-19 Supplements Sep 23, 2020 4 years ago
COVID-19 Supplements: Spanish researchers from the Hospital Del Mar, Barcelona led by Dr Roberto Güerri-Fernández presented a new research at the ESCMID Conference on Coronavirus Disease (ECCVID, currently held online 23-25 September) that shows that having a lower level of zinc in the blood is associated with a poorer outcome in patients with COVID-19.
Past studies have shown that in...
COVID-19 Herbs: It was announced last Saturday that The World Health Organization has finally endorsed a protocol for testing herbal medicines as potential treatments for the COVID-19 disease coronavirus and other epidemics. https://www.afro.who.int/news/expert-panel-endorses-protocol-covid-19-herbal-medicine-clinical-trials
The COVID-19 pandemic has raised the issue o...
HIV Drugs: According to researchers from the University of Washington-Seattle, the commonly used HIV drug that is to treat those infected and also individuals using it as a prophylaxis or in PrEP protocols can induce a type I/III interferon-associated signature and inflammation throughout the gut.
It should be noted that long term inflammation of any kind can lead to a variety of chronic ...
Source: COVID-19 Herd Immunity Sep 23, 2020 4 years ago
COVID-19 Herd Immunity: Researchers from University of Georgia have developed a new model that proves that achieving herd immunity to COVID-19 is an impractical public health strategy.
The study findings were published in the journal: Proceedings of the National Academy of Sciences. https://www.pnas.org/content/early/2020/09/21/2008087117
Currently attempts to controlling COV...
Source: Coronavirus Latest Sep 23, 2020 4 years ago
Coronavirus Latest: Contrary to all the hyped up news about potential drug candidates discoveries, latest research revelations about the virus pathogenesis, about advances in monoclonal antibody therapies and about COVID-19 vaccines that are in expected to be available before the end of the year thanks to the White House intervention, the COVID-19 pandemic is far from going to be over as the ever ...
COVID-19 News: More and more each day we are learning of the various damaging and disastrous effects the SARS-CoV-2 coronavirus has on the human host body not only on those that are just infected and are going through severe conditions but also in term of long term health complications of those who had recovered from mild or moderate symptoms or were asymptomatic. The COVID-19 disease is now...
COVID-19 Latest: Researchers from University of Manchester-UK have made a startling discovery that the SARS-Cov-2 damages blood marrow cells especially the myeloid cells originating from the hematopoietic stem cells of the bone marrow.
The study team found that of the myeloid cells damaged by the novel coronavirus, the monocytes are in particular affected.
The study results were pu...
Source: Strokes And COVID-19 Sep 22, 2020 4 years ago
Strokes-COVID-19: It is already being reported by medical professionals all over the world about a sudden increase of unexplained strokes in the last few months. Among those that were already tested positive for COVID-19 but were either asymptomatic or had recovered from severe, moderate or even mild conditions of the SARS-CoV-2 infection, the risk of strokes was found to be high but there are man...
Influenza-Flu: Researchers from St Jude Children's Research Hospital have found in a study that eradicating certain types of nasal bacteria actually helps to cut down the risk of contracting viral influenza strains.
Dr Stacey Schultz-Cherry, Ph.D., and Dr Jason Rosch, Ph.D., both of
St. Jude Infectious Diseases, led the respiratory bacteria research.
Credit: St. Jude Children's Research ...
Pediatrics: Researchers from Case Western Reserve University-Ohio, Duke University-North Carolina and Rutgers Robert Wood Johnson Medical School-New Jersey have discovered a new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children.
The study team first screened an RNA-biased small molecule library using a peptide-displacement ...
Source: COVID-19 Treatments Sep 22, 2020 4 years ago
COVID-19 Treatments: Medical researchers and physicians are now trying interrupt the SARS-CoV-2 coronavirus before it gets into the lungs and the rest of the body and starts ravaging the body, targeting not only the lungs, heart and blood vessels but even the cerebrospinal fluids, the brain, the kidneys, the gastroenterological tract , the male testis to even the immune system itself.
The...
COVID-19 News: Doctors and researchers from the department of Digestive Surgery, University Hospitals of Geneva, Switzerland have discovered that the SARS-CoV-2 coronavirus can be found in the gallbladder wall of COVID-19 patients and that COVID-19 can also mimic acalculous acute cholecystitis.
Two case reports of COVID-19 patients developing cholecystitis were mentioned in a study fi...
Source: COVID-19 Scams-Russia Sep 22, 2020 4 years ago
COVID-19 Scams: It was announced that Russia has approved R-Pharm's Coronavir treatment for outpatients with mild to moderate COVID-19 infections and the antiviral drug could be rolled out to pharmacies throughout the country as soon as next week, the company said on Friday.
The drug’s approval as a prescription drug follows the green light for another Russian COVID-19 drug, Avi...
Source: COVID-19 Research Sep 22, 2020 4 years ago
COVID-19 Research: A study led by researchers from University of Bristol-UK that also involved scientist from Max Planck Institute-Germany, University of Heidelberg-Germany and Geneva Biotech Sàrl-Switzerland has discovered a druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells.
The stud findings are published in the peer ...
V483G Mutation: Researchers And health Officials are warning that that a mutant strain of the SARS-CoV-2 coronavirus, the V483G strain is fast making appearances in various countries including India, Brazil, The Middles-East, UK and even in the United States.
According to genomic experts and immunologist, the V483 strain is resistant to the neutralizing properties of antibodies and ...
Source: Post-COVID Myocarditis Sep 21, 2020 4 years ago
Post-COVID Myocarditis: As a result of alarming data showing that a majority of recovered COVID-19 patients have some sort of heart tissue damage after being infected with the SARS-CoV-2 coronavirus irrespective of whatever the conditions they had endured ie from mild, moderate , severe or asymptomatic, there is a huge rush by many concerned to go for heart screenings. https://www.thailandmedical....
Source: America Coronavirus Sep 21, 2020 4 years ago
America Coronavirus: American official COVID-19 infection rates hits 6.81 million and 200,014 Americans have died from the COVID-19 so far though actual figures are expected to be much higher. Americans are expected to have a great time for the rest of the year and also an interesting year end festive season never experienced in its history starting from next month’s Halloween as many more a...
COVID-19 Latest: A new study by French researchers from Aix-Marseille University, IHU-Méditerranée Infection, Institut Paoli Calmettes and Laboratoire d’Immunologie-Marseille, including the controversial French physician and microbiologist Professor Dr Didier Raoult have discovered that the SARS-CoV-2 coronavirus basically causes immunoparalysis in the human hos...
COVID-19 Scams: Of all the stupidity and craziness which not many people are questioning (the intelligence levels in America has sunk to its lowest!) is the new American standard for drug approvals set by the US FDA under the Trump administration in which as long you can demonstrate somehow by whatever means that a drug is able to shorten hospitalization stays, Voila! You get approved and you can ...
COVID-19-News: Initial hypothesis that the it was the cytokine storms as a result of SARS-Cov-2 infections that were destroying various organ tissues including the heart, kidneys, intestines and even brain tissues are now being replaced with the stark fact it is actually the SARS-CoV-2 coronavirus itself that is causing these issues and in some cases it might be also compounded by the inflammatory...
Drugs-COVID-19: Spanish researchers from the Department of Cell Biology at the University of Malaga (UMA) and the Andalusian Centre for Nanomedicine and Biotechnology (BIONAND) have identified 4-Phenylbutiric acid or 4-PBA as a possible drug candidate to treat the various inflammatory and immune issues resulting from the SARS-CoV-2 coronavirus infection that causes COVID-19 disease.
The s...
Source: Disinfectants-COVID-19 Sep 20, 2020 4 years ago
Disinfectants-COVID-19: To curb the problem of current COVID-19 disinfectants taking time to sanitize surfaces and the impracticability of using them on high-contact areas such as door handles, elevators, and bannisters due to ‘wearing-off' effects, researchers from the University of Central Florida (UCF) are co-developing a new, rapid-acting, long-lasting disinfectant spray that instant...
Source: COVID-19 Research Sep 20, 2020 4 years ago
COVID-19 Research: Japanese researchers from the Kyoto Prefectural University of Medicine and Osaka University have engineered to create soluble ACE2 (sACE2) in human cells that have enhanced affinity to receptor-binding domain (RBD) of the SARS-CoV-2 thus serving as decoy while also neutralizing the novel coronavirus.
The research findings were published on a preprint serve and are curre...
Source: Therapeutic Herbal Teas Sep 19, 2020 4 years ago
As a result of overwhelming response and also a new promotional program with postal authorities and also with certain well-wishers who wish to make our specially blended therapeutic herbal teas more accessible to as many Americans as possible to better equipped themselves with the coming cooler season and the impending COVID-19 second wave, Thailand Medical News announces that we now offer a...
Mpro Inhibitors: A new study led by researchers from the university of Arizona with additional support from the University of Athens shows that all previous studies indicating that Mpro Inhibitors Such As Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, And Shikonin have antiviral properties against the SARS-CoV-2 coronavirus are invalidated as the new research shows that these Mpro inhibitors ar...
Source: Ketogenic Diet And COVID-19 Sep 19, 2020 4 years ago
Ketogenic Diet And COVID-19: Researchers in a new study led by Yale School of Medicine but also involving scientist from New York University Langone Health and Washington University School of Medicine, advocate a ketogenic diet (A diet in high fat, low carbohydrate) for elderly COVID-19 patients and even those not infected yet it is capable of mitigating clinical outcomes of COVID-19 in this vulne...
Source: Coronavirus Breakthrough Sep 19, 2020 4 years ago
Coronavirus Breakthrough: Researchers from University of Kentucky College of Medicine in a new study have discovered that as a result localized inflammation in the lungs, a deficiency of the anticoagulant protein S results that leads to thrombosis in COVID-19 patients. The localized inflammation also leads to elevated levels of tissue factor, a protein found in blood that initiates the clott...
A new study by experts from the Department of Biochemistry of the University of Wisconsin-Madison reveals that the genetic variants of human angiotensin 2 or ACE2 receptors can have altered recognition by SARS-CoV-2 coronavirus, the causative agent COVID-19) pandemic.
Comprehending how human ACE2 genetic variants differ in their recognition by SARS-CoV-2 can have a major impact in le...
Source: Strokes And COVID-19 Sep 19, 2020 4 years ago
Strokes And COVID-19: According to a new study from University of Alabama at Birmingham led by Dr Chen Lin, M.D., an assistant professor in the Department of Neurology, stroke patients who also have COVID-19 showed increased systemic inflammation, a more serious stroke severity and a much higher rate of death, compared to stroke patients who did not have COVID-19.
The new study finding co...
Fatigue: Study findings from a new research by Dr Liam Townsend, St James's Hospital and Trinity Translational Medicine Institute, Trinity College, Dublin, Ireland, and colleagues showed that that persistent fatigue occurs in more than half of patients recovered from COVID-19, regardless of the seriousness of their infection.
The study findings were presented online at the recent ESCM...
ACE2: Eight months into the COVID-19 pandemic which started in Wuhan, China and spread to the rest of the world (thanks due to the incompetency of a certainHealth Organization) with disastrous effects both on the lives and economic aspects of billions of people globally with the exception of China which seems to have escaped the disastrous effects mysteriously, global researchers are now realizing...
Source: Coronavirus Supplements Sep 18, 2020 4 years ago
Coronavirus Supplements: Researchers from the University of Nebraska Medical Center and Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring have demonstrated in vitro studies that bromelain extracted from pineapples is able to inhibit the SARS-CoV-2 coronavirus in Vero E6 cells via a multitude of ways.
The study findings are published on a preprint server and are...
Source: COVID-19 Antibodies Sep 18, 2020 4 years ago
COVID-19 Antibodies: A new research by scientists from the Rockefeller University and the University of North Carolina-Chapel Hill shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.
The study results were published on a preprint server and are pending peer review. https://www.biorxiv.o...
Source: COVID-19 Research Sep 18, 2020 4 years ago
COVID-19 Research: Contrary to a fallacy that has been installed in many through fake misinformation disseminated by so called medical ‘experts’ and health organizations during the early stages of the COVID-19 pandemic that only the elderly are susceptible to COVID-19 and that younger adults are most likely to withstand the infections and only endure mild symptoms, new data is showing ...
Source: Coronavirus Latest Sep 17, 2020 4 years ago
Coronavirus Latest: Researchers from the Crick's Structural Biology of Disease Processes Laboratory at the Francis Crick Institute-London have found that the spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2.
The structural states of the SARS-CoV-2 spike protein, binding to the huma...
Botox injections of high doses might lead to bone loss according to researchers from New York University.
Typically botox injections to manage jaw and facial pain do not result in clinically significant changes in jaw bone when used short term and in low doses, according to researchers at NYU College of Dentistry. However, they found evidence of bone loss when higher doses were used.
Their...
Source: Omega-3 Supplements Sep 17, 2020 4 years ago
Omega-3 Supplements: A new meta-analysis study of 40 past studies involving a total of more than 135,267 participants indicates that EPA and DHA supplementation reduces multiple types of cardiovascular risk and also improves hearth health.
The study findings were published in the peer reviewed journal: Mayo Clinic Proceedings. https://www.mayoclinicproceedings.org/article/...
Source: Coronavirus Antivirals Sep 17, 2020 4 years ago
Coronavirus Antivirals: Researchers from University of Chinese Academy of Sciences, Shanghai-China have identified the antibiotic Ceftazidime as possible antiviral candidate to inhibit SARS-CoV-2 coronavirus and treat the COVID-19 disease.
The research findings were published on a preprint server and have yet to be peer reviewed.
https://www.biorxiv.org/content/10.1101/2020.09.14.295956v1
...
Source: COVID-19 Immunotherapy Sep 17, 2020 4 years ago
COVID-19 Immunotherapy: Researchers from Corvus Pharmaceuticals Inc-California, Temple University-Philadelphia and Icahn School of Medicine at Mount Sinai-New York in a phase 1 clinical trial have demonstrated that using a Inhibitor Of CD73 Enzymatic Activity called CPI-006, the researchers were able to induce the effective B Cell and Humoral response to SARS-CoV-2 infection in COVID-19 patients e...