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COVID-19 Drugs: Remdesivir has so far emerged as another controversial drug that was approved by the US FDA under the Trump administration for emergency use despite the fact that it not clearly demonstrated its efficacy against the SARS-CoV-2 coronavirus nor was there any long term safety studies ever conducted on it use. It was granted approval merely on the basis that it shortened hospitalizatio...
COVID-19 Rehab: Eight Months down the COVID-19 pandemic, globally there has been more than 805,000 deaths officially reported or an average of one death every 20 seconds. Officially there has been about 23.5 million people globally infected but the real realistic figure could come close to about 310 million people (or about 18 people getting infected every second). Contrary to lies or misinformati...
HIV News: The trend for HIV drug research is now shifting towards drugs with long lasting effects without the need for HIV patients to adhere to stringent daily regimens and doses which can be quiet stressful at times.
Scientists from the University of Utah Health in collaboration with researchers from the National Institute of Allergy and Infectious Diseases (NIAID), Beth Israel Deacones...
Source: Cardiovascular Disease Aug 23, 2020 4 years ago
Cardiovascular Disease: A new study led by Australian researchers from Edith Cowan University, University of Western Australia, Flinders University, University of Sydney and also American researchers from Harvard Medical School, University of Minnesota and HealthPartners Institute-Minneapolis shows that cruciferous vegetables could be the most beneficial when it comes to preventing advanced blood ...
Source: COVID-19 Research Aug 23, 2020 4 years ago
COVID-19 Research: A new bioinformatics study by researchers from University of Pennsylvania and Shanghai University studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics have uncovered that cytokine-cytokine receptor interactions, P53 signaling pathways, and apoptosis are the main...
COVID-19 Herbs: Various computational molecular docking studies have shown that phytochemicals present in green tea or Camellia sinensis has the potential to inhibit the SARS-CoV-2 coronavirus.
https://www.sciencedirect.com/science/article/pii/S0944711320301185?via%3Dihub
https://www.tandfonline.com/doi/full/10.1080/07391102.2020.1779818
https://www.researchsquare.com/article/rs-19...
COVID-19 Vaccine: Researchers from Washington University School of Medicine-St. Louis have developed a vaccine that targets the SARS-CoV-2 coronavirus and can be administered through the nose in one dose.
Studies in mice models susceptible to the SARS-CoV-2 coronavirus have proven to be effective in preventing infection.
The study team next plans to test the vaccine in nonhuman pri...
COVID-19 Rehab: Numerous studies have already demonstrated that COVID-19 also damages the heart, ie damage either caused by the SARS-CoV-2 coronavirus itself, or from inflammation triggered by the immune system's response to the virus or from increased clotting in heart vessels.
However there is now emerging evidence that heart damage may persist even after the patient recovers and, i...
Source: U.S. Medical News Aug 22, 2020 4 years ago
U.S. Medical News: In what is shocking the medical community not only in America but also internationally, the white house has issued a new policy order midweek that removed all regulatory powers from the US FDA with regards to regulating and standardizing all medical laboratory test.
The new order which even stunned the US FDA, shocked health experts and laboratories because of its timin...
COVID-19 News: A new international genomic study led by researchers from the University of California-Davis alarmingly indicates that humans are not the only species facing a potential threat from SARS-CoV-2. The study team discovered that many of the 410 different species of vertebrates included in the study comprising birds, fish, amphibians, reptiles and mammals were vulnerable due to the prese...
Source: COVID-19 Mutations Aug 22, 2020 4 years ago
SARS-CoV-2 Mutations: A new machine learning model incorporating a new generation of artificial intelligence (AI), developed by researchers at Michigan State University indicate that mutations to the SARS-CoV-2 genome have made the virus more infectious.
The machine learning model, developed by lead researcher Dr Guowei Wei, Professor in the departments of Mathematics and Biochemistry and ...
Source: COVID-19 Immunology Aug 21, 2020 4 years ago
COVID-19 Immunology: Australian scientist from Monash University, the University of Melbourne and James Cook University have made a disturbing discovery that infection with the SARS-CoV-2 coronavirus might compromise the activation of the CD8+ T-cell responses that would usually ameliorate disease and drive recovery.
The research findings are published on a preprint server...
Source: Europe Covid-19 News Aug 21, 2020 4 years ago
Europe Covid-19 News: Europe is basically reverting back to the early days of the pandemic as new cases of COVID-19 infections are reaching record highs again.
Reports are showing that the pandemic was rebounding across the continent, often due to travel, summer holidays and parties plus youths and younger adults are adopting a carefree attitude and disregarding social distancing measures...
Source: COVID-19 Genomics Aug 21, 2020 4 years ago
COVID-19 Genomics: Researchers from Sanford Burnham Prebys Medical Discovery Institute and the University of California-San Francisco have discovered that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host. These proteins are also most probably responsible fo...
Source: COVID-19 Vaccines Aug 21, 2020 4 years ago
COVID-19 Vaccines: Pfizer Inc. and BioNTech has released additional Phase 1 safety and immunogenicity data from their ongoing U.S. study of the BNT162 mRNA-based vaccine program against SARS-CoV-2, which has advanced into Phase 2/3 evaluation.
The clinical data is published on a preprint server and is pending peer-review. https://www.medrxiv.org/content/10.1101/2020.08...
COVID-19 News: Researchers from Peking University Health Science Center-Beijing, Beijing University of Chemical Technology and Nanjing University Medical School in a new study have reported that different kinds of whey protein obtained from different sources ie cow’s or goat milk exhibited inhibitory properties against the SARS-CoV-2 coronavirus in vitro studies involving vero cells. However...
Source: COVID-19 Antibodies Aug 21, 2020 4 years ago
COVID-19 Antibodies: It was announced yesterday that the US FDA has put on hold the emergency approval of blood plasma as a potential COVID-19 treatment.
Only a week ago, Mayo Clinic came up with press releases that a massive convalescent plasma therapy trial study was a success.
Thailand Medical News was the first to report that the study results were nothing more than misinf...
Source: COVID-19 And Children Aug 21, 2020 4 years ago
COVID-19 And Children: Although children infected with the SARS-CoV-2 coronavirus seems to either appear asymptomatic or merely experience mild symptoms, worrying emerging studies are causing a concern that besides multi-inflammatory syndrome disease or MIC-C that could manifest much later after infection, the virus could be in the meanwhile be affecting children in a variety of ways, one of which...
COVID-19 Study: The latest post-mortem examinations performed on 10 dead COVID-19 patients by researchers from Imperial College London showed conditions far worse that seen in earlier autopsy studies.
Blood Clots In Lungs
The researchers found that all dead patients had massive lung injuries and early scarring of the lungs as a result of the SARS-CoV-2 coronavirus, as well as injury to th...
Diabetes News: Researchers from Salk Institute-California have made a major breakthrough in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.7 million Americans with a cost of US$14.5 billion annually.
Utilizing stem cell technology, the research team generated the first human insulin-producing pancreatic cell clusters abl...
Source: Coronavirus Latest News Aug 20, 2020 4 years ago
Coronavirus Latest News: Researchers are warning that foodborne contamination and transmission of SARS-CoV-2 should not be overlooked or even downplayed in recent cases of new COVID-19 clusters appearing in China, Vietnam and even New Zealand (Despite the New Zealand premier going public and saying that this was not the case in New Zealand, many researchers felt otherwise. Some also suspect trade ...
Coronavirus News: A new study has confirmed that a high proportion of children in the United States are asymptomatic and infected with the SARS-CoV-2 coronavirus, with high viral loads in their airways and are basically silent spreaders of the COVID-19 disease.
The study findings were published in the Journal of Pediatrics. https://www.jpeds.com/article/S0022-3476(20)31023-4/fulltext
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Source: Germany and COVID-19 Aug 20, 2020 4 years ago
Germany and COVID-19: Authorities in Germany are on high alert as the country recorded 1,707 new COVID-19 infections in the last 24 hours, the highest ever daily number of infections since April.
The country had initially fared much better than its neighbors as a result of strict measures during the start of the global pandemic. It also had the among the lowest mortality rates in Europe w...
COVID-19 News: It is becoming obvious that the SARS-CoV-2 coronavirus is changing as it spreads to different countries and regions. This is due spontaneous adaptive mutations, shaped by the different selection pressures exerted by varying environmental conditions and hosts.
A new study by Indian researchers from the JIS Institute of Advanced Studies and Research-Kolkata and the School of ...
COVID-19 Drugs: Canadian researchers from Queen’s University-Ontario Novateur Ventures Inc.-Vancouver in a new study propose that two generic anti-inflammatory drugs, zileuton and montelukast typically used in asthma treatments, be used to treat COVID-19 patients because of their potential to dampen disease progression and severity.
The research findings were publi...
Source: COVID-19 Immunity Aug 20, 2020 4 years ago
COVID-19 Immunity: A new study led by researchers from Harvard have shown that high levels of certain cytokines may also prevent individuals who are infected with COVID-19 from developing long-term immunity as affected patients were observed to make very few of the type of B cells needed to develop a durable immune response.
It has already been known that the release of massive amou...
COVID-19 Drugs: Researchers from COVID-19 Radboud University Medical Center-Netherlands, University Medical Center Utrecht-Netherlands and University of Bonn-Germany in a new study have shown that patients with hypoxia responded positively to treatment with the drug lanadelumab, a Kinin B2 receptor antagonist.
These study findings have led to a follow-up study at ten Dutch hospi...
Happy Hypoxia: Researchers from the Icahn School of Medicine at Mount Sinai in a new study claim that COVID-19 causes significant dilation of the blood vessels of the lung, specifically the capillaries. This vasodilation is what is is contributing to the very low oxygen levels often seen in COVID-19 respiratory failure and also helps explain why the disease behaves differently than tradition...
Source: Nifedipine and Amlodipine Aug 19, 2020 4 years ago
Nifedipine and Amlodipine: While the COVID-19 pandemic continues to wreak havoc globally, there have been concerns on medications taken by patients for various cardiometabolic disorders as they are more vulnerable to the coronavirus infection.
It has been found that patients with diabetes, hypertension, and other comorbidities are at higher risk of death from the virus.
https://www.nature...
Source: Gut Microbiome and COVID-19 Aug 19, 2020 4 years ago
Gut Microbiome and COVID-19:Researchers from Heifei, China in a new study claim that the intestinal microbiome of human hosts are altered as a result of the SARS-CoV-2 infection, resulting in the increased production of IL-18, a pro-inflammatory cytokine in COVID-19 patients, causing inflammatory conditions and cytokine storms that can lead to severe disease progression.
The study finding...
Stem Cells shielded via encapsulation in an alginate based hydrogel were found to be effective in reducing damage caused by heart attacks according to a new study by bioengineers and surgeons from Rice University and Baylor College of Medicine (BCM).
A postdoctoral research associate at Rice University, displays a
vial of alginate capsules loaded with mesenchymal stem cells.
(Photo by Jeff Fitlo...
COVID-19 News: It has been generally assumed by medical experts and physicians that once a person recovers from COVID-19,(recovery in this case as per the US CDC guidelines and criteria) it would take a couple for weeks for the viral clearance and that the person would be free from the virus. However due to more cases of emerging long term health complications among recovered and even asymptomatic...
COVID-19 Latest: Italian researchers from Ca' Granda Ospedale Maggiore Policlinico, one of the oldest and largest hospitals in Milan in a new study report that the SARS-CoV-2 coronavirus not only infects and causes thyroid issues but is also capable of causing throxicosis.
The term thyrotoxicosis refers to the hypermetabolic clinical syndrome resulting from serum elevations in thyroid...
D614G Strains: A news agency report of a doctor from a South-east asian country that cannot even control the COVID-19 infections in its own backyard, claiming that the D614G strain of the SARS-CoV-2 coronavirus is less deadly is an example of total irresponsible reporting and should be deemed as fake news and misinformation by health authorities across Asia immediately. There are no su...
Source: COVID-19 Antibodies Aug 18, 2020 4 years ago
COVID-19 Antibodies: A new study by researchers from New York University reports that up to about 75% of recovered COVID-19 patients have low neutralizing antibody titers. The study findings also showed that high titers of multiple antibody isotypes against both the SARS-CoV-2 spike receptor-binding domain and nucleoprotein are needed for effective and better neutralization.
The study fin...
COVID-19 News: According to new study from the University of California-Davis and the Icahn School of Medicine-Mt. Sinai influenza viruses can spread through the air on dust, fibers, and other microscopic particles.
The research findings have shocking obvious implications for SARS-CoV-2 coronavirus transmission as well. Many medical experts and researchers are concerned about the new find...
COVID-19 Drugs: Canadian based Bold Therapeutics, a clinical-stage biopharmaceutical company, have recently generated more key data supporting the rapid clinical development of a new therapeutic drug called BOLD-100 as an antiviral against the SARS-CoV-2 coronavirus.
The therapeutic drug BOLD-100 is a first-in-class ruthenium-based small molecule drug which selectively inhibits stress-ind...
Source: COVID-19 Research Aug 18, 2020 4 years ago
COVID-19 Research: Various new emerging studies are indicating that that low levels of gelsolin, an immune system protein are associated with severe illness and organ failure in COVID-19 patients.
The focus on gelsolin levels and its correlations to COVID-19 severity was initially brought up by BioAegis Therapeutics Inc., a clinical stage, private company developing therapies fo...
Source: Anacardic Acid From Cashew Nut Shells Aug 18, 2020 4 years ago
Anacardic Acid, a compound extracted from the shells of Cashew nuts is able to promote the repair of myelin in damaged nerve cells and tissues according to a new research by scientists from Vanderbilt University Medical Center.
The protective sheath surrounding nerves is known as myelin. Damage to this covering or demyelination is a hallmark of multiple sclerosis and numerous other neurol...
Source: COVID-19 Breaking News Aug 18, 2020 4 years ago
COVID-19 Breaking News: A new study by researchers from Institut Pasteur-Paris, Sorbonne Université-Paris, Service de Médecine-Paris, and Genalyte Inc -California confirms that having previous immunity against common coronaviruses (alpha and beta) cannot protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The news study contrad...
Coronavirus News: A study conducted by scientists from Dalhousie University in Halifax, Canada, has alarmingly discovered that many species of marine mammal are highly vulnerable to infection with the SARS-CoV-2 coronavirus.
Marine mammal species predicted to be susceptible belong to the IUCN Red list. Many of the species predicted to be susceptible are members of the IUCN Red list of Threa...
Source: Supplements For COVID-19 Aug 17, 2020 4 years ago
Supplements for COVID-19: Nitrate supplements could help the elderly especially in the COVID-19 context with regards to breathing and lung clearance according to researchers from the University of Florida.
Past studies have showed that nitrate supplements help muscles by improving use of calcium in the muscle. This finding that it's additionally affecting power is significant, es...
Source: COVID-19 Research Aug 17, 2020 4 years ago
COVID-19 Research: A new study by researchers from the Department of Biochemistry and Molecular Biology at Colorado State University have made a breakthrough in discovering that the N proteins of the SARS-C0V-2 coronavirus is able to form biomolecular condensates that helps the spread of virions and viral proteins to nearby healthy host cells.
The study by Dr Eric Ross and Dr Sean Cascari...
Source: South Korea COVID-19 News Aug 17, 2020 4 years ago
South Korea COVID-19 News: South Korea is going through a new surge of COVID-19 cases almost reminiscent of the first time the SARS-CoV-2 coronavirus struck in the country.
This time instead of a Christian cult church, a protestant church is involved with thousands of its members linked to a coronavirus cluster in Seoul already made to undergo compulsory quarantine.
On Monday, Sout...
D614G Mutation: Since the original debut of the SAR-CoV-2 coronavirus in December 2019, most of the South-East Asian countries like Thailand, Malaysia, Philippines, Indonesia, Vietnam, Myanmar, Cambodia and even others like Hong Kong and Taiwan were spared from the severe symptoms of the disease and high death rates as we were all only exposed to the milder strains of the SARS-CoV-2 coronavirus. A...
Coronavirus News: Tiredness And fatigue are two common complains by individuals who recovered from COVID-19, either from the severe forms of the disease or simply those who had experienced mild and moderate symptoms upon being tested. Muscular pains are also another common accompanying symptom. Even individuals who have tested positive in the early stages and were typically asymptomatic are ...
Source: COVID-19 Heart And Cardiovascular Conditions Aug 17, 2020 4 years ago
COVID-19 Heart And Cardiovascular Conditions: As of Monday (17th August ), the COVID-19 disease is seeing a new surge in infection cases all around the world from South Korea, Japan To France, Germany and Hong Kong. Official figures are now at a total of almost 21.7 million cases (realistic figures could be as high as 10 to 12 times) and the number of COVID-19 deaths globally has now reached more ...
COVID-19 News: Researchers from Chongqing, China have developed membrane nanoparticles from ACE2-rich cells with a potent capability to block potential SARS-CoV-2 infections.
When developing therapeutic drugs or agents, one of the prime targets for researchers is the angiotensin-converting enzyme 2 (ACE2), the primary receptor for SARS-CoV-2 spike glycoprotein (S1 subunit), whic...
Source: Latest COVID-19 Conspiracy Theory Aug 16, 2020 4 years ago
Latest COVID-19 Theory: We at Thailand Medical News typically avoid any kind unsubstantiated claims or theories and ‘cooked up’ studies and in fact we have been amused at the quality of misinformation that there is on the internet and some even perpetrated by health organizations, regulatory bodies, pharma giants, medical researchers and governments using phenomenal resources and...
Source: COVID-19 Research Aug 16, 2020 4 years ago
COVID-19 Research: Scientist from the University of California, San Francisco found that when the SARS-CoV-2 virus infects human cells, the infected cell grows multi-pronged tentacles that are studded with viral particles. These filaments, called filopodia, reach out to still-healthy neighboring cells, which then bore into the cells’ bodies and infect the healthy cells with vi...
Source: COVID-19 Exclusive Aug 15, 2020 4 years ago
COVID-19 Exclusive: Researchers from University College London-UK, Imperial College London-UK, University of Oxford-UK, Université de la Réunion-France and CIRAD-France have in a detailed study of the various genomic sequencings and mutations of the SARS-CoV-2 coronavirus discovered a hint that could possibly imply that the virus could indeed be evolving to escape the immunity system...
Source: Aromatherapy Treatments Aug 15, 2020 4 years ago
Aromatherapy Treatments: Of late, there has been many companies in the United States, Britain, Australia, Hong Kong and Singapore making fake claims and disseminating misinformation that the use of essentials and diffusers would help with prevention and treatment of COVID-19.
The public is warned that to date there are no proven medical or scientific studies that demonstrate that any essent...
HIV Drug News: Researchers at the George Washington University in a new study have discovered that Fingolimod, a US FDA-approved immunosuppressive drug used to treat multiple sclerosis flare-ups, may be used to effectively block HIV infection and reduce the latent virus reservoir.
The research findings were published in the journal: PLOS Pathogens. https://journals.plos.org/plospathogens/...
Coronavirus News: Sweden’s initial goal to attain herd immunity against the COVID-19 disease by adopting a policy of allowing the controlled spread of Covid-19 viral infection among the population has so far failed to deliver the expected results.
Researchers from the University College of London commenting on recent antibody testing clinical and research findings, in a study paper publis...
Latest COVID-19 News: A team researchers from the University of Alabama at Birmingham-U.S., Jagiellonian University Medical College-Poland and Nencki Institute of Experimental Biology-Poland postulate that one of the reasons of the anomalous traits of the SARS-CoV-2 versus existing human coronaviruses in terms of the severity of the disease it causes and also the long term health complicatio...