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Source: Nature’s Journal Of Science, doi: 10.1038/d41586-018-05573-4  Jul 12, 2018  6 years ago
Clinical use of the anticancer drug methotrexate can be limited by its high toxicity. It emerges that a diet rich in the amino acid histidine increases the effectiveness of methotrexate treatment and lowers toxicity in mice.   Methotrexate was one of the first approved anticancer drugs, and is a cornerstone of modern chemotherapy for the treatment of certain solid tumours and blood cancers...
Source: Multiple  Jul 11, 2018  6 years ago
Abnormal accumulations of a protein called tau can collect inside neurons, forming tangled threads and eventually harming the synaptic connection between neurons. Credit: National Institute on Aging. UT Southwestern   Scientists ID genesis of disease, focus efforts on shape-shifting tau. Scientists have discovered a "Big Bang" of Alzheimer's disease – the precise point a...
Source: WHO (World Health Organisation)  Jul 11, 2018  6 years ago
The World Health Organization said Tuesday it was awaiting formal approval from the Democratic Republic of Congo to send in unlicenced Ebola medication to help rein in an outbreak of the deadly virus.   The UN health agency and DRC authorities are rushing to contain the outbreakthat has sickened 54 people in recent weeks, including 25 who have died.   A "major innovation in t...
Staff Writer, TMN  Jul 10, 2018  6 years ago
International health insurance for expats: How to choose between local insurance or an international health insurance plan. When is expat medical insurance necessary? At what point do you need to consider international health insurance? How can you choose between so many expat medical insurance plans? There are numerous factors to consider when looking to live and work abroad, n...
Source: Multiple  Jul 11, 2018  6 years ago
A new approach established at the University of Zurich sheds light on the effects of anti-cancer drugs and the defense mechanisms of cancer cells. The method makes it possible to quickly test various drugs and treatment combinations at the cellular level. Cancer cells are cells over which the human body has lost control. The fact that they are transformed body cells makes it all the more difficul...
Source: Marshall University Joan C. Edwards School of Medicine  Jul 11, 2018  6 years ago
New research from a team at the Marshall University Joan C. Edwards School of Medicine demonstrates that the Na/K-ATPase oxidant amplification loop (NAKL) is intimately involved in the aging process and may serve as a target for anti-aging interventions. The researchers were also able to successfully demonstrate the therapeutic potential of pNaKtide, a synthetic peptide, in improving impaired phys...
Source: Fierce Biotech  Jul 13, 2018  6 years ago
Scientists at UT Southwestern Medical School have spent the last two decades studying autophagy, the process cells use to throw out toxic substances that endanger their health. They discovered autophagy not only helps the body fight off infections, but it also protects against many age-related diseases such as cancer and neurological disorders. Autophagy The findings raised a question: Could b...
Staff Writer, TMN  Jul 12, 2018  6 years ago
Scientists on the hunt for anti-aging drugs say they've made an advance with tantalizing potential: Two experimental drugs appear to safely boost the immune systems of elderly humans. The researchers stress that more research is needed to confirm the findings and show the drugs are safe. And at least one researcher says the findings are based on a relatively small number of people and used m...
Source: Michigan Medicine  Jul 16, 2018  6 years ago
New Research finds that more men have suboptimal testosterone levels than previously known, and it may be putting these men at risk. Testosterone hormone replacement therapy is great tool in preventing  diseases associated with aging in men. A male’s total testosterone level may be linked to more than just sexual health and muscle mass preservation, a new study finds. Low amounts of th...
Source: multiple  Jul 10, 2018  6 years ago
More Reasons to Take Fish Oil Clinical trials have focused on the cardiovascular benefits of omega-3 fatty acids derived from fish oil.   More recent data show the biological effects that omega-3s confer extend beyond cardiovascular issues and impact virtually every aspect of our health.   A meta-analysis published last year found that the highest co...
Source: multiple  Jul 09, 2018  6 years ago
Next Frontier in Fight Against Aging As longevity scientists look to target and stop aging, many researchers are focusing on geroprotectors, compounds capable of preventing or even reversing aging at the cellular level. Senescent cells are particularly troublesome when they enter the stage in which they can no longer properly divide and function. As cells become dysfunctiona...
Source: Journal of the Endocrine Society  Jul 08, 2018  6 years ago
A new case report in the Journal of the Endocrine Society documents how a patient's use of a common biotin supplement, also known as vitamin B7, caused her to have clinically misleading test results, which prompted numerous consultations and unnecessary radiographic and laboratory testing. Maya Styner, M.D., Associate Professor, University of North Carolina School of Medicine. Cre...
Source: www.ncbi.nlm.nih.gov  Jul 07, 2018  6 years ago
New clinical study supports astaxanthin supplementation for protecting skin from damage associated with sun exposure.   A new randomized, double-blind, placebo-controlled clinical trial provides stronger evidence for the protective role of algal-derived astaxanthin against skin deterioration caused by ultraviolet (UV) light. FujiFilm’s research group conducted the resea...
Source: chalmers.se  Jul 06, 2018  6 years ago
You take supplements to stay healthy — but some of them may be doing more harm than good. Certain dietary iron supplements may aid the development of colon cancer in humans, according to new research out of Sweden’s Chalmers University of Technology.   Scientists found that two strains of iron — ferric citrate, which is found in vitamin supplements, and ferric EDT...
Source: multiple  Jul 05, 2018  6 years ago
Researchers examined brain development in babies whose mothers received folic acid supplements during the second and third trimesters of their pregnancies.   Folic acid supplements of 400 micrograms per day are recommended for women before conception and throughout the first trimester of pregnancy. This dose of folic acid is proven to prevent neural tube defects in early pregnanc...
Source: multiple  Jul 04, 2018  6 years ago
A scientific paper has revealed that some nutrients found in food may help reduce the symptoms of psychotic illness, when used in the early stages of treatment.   The systematic review, led by Dr Firth, honorary Research Fellow at The University of Manchester and Research Fellow at NICM Health Research Institute, Western Sydney University an examined if nutrient supplementation cou...
Source: multiple  Jul 03, 2018  6 years ago
A dietary supplement derived from glucose increases muscle-force production in the Duchenne muscular dystrophy (DMD) mouse model by 50% in ten days, according to a study conducted by researchers from Université Laval's Faculty of Medicine and Centre hospitalier universitaire (CHU) de Québec Research Centre-Université Laval. The results, which were recently published in the...
Source: cff.org  Jul 02, 2018  6 years ago
An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with CF.   An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis (CF), according to research published online in the American Journal of Respiratory and Critical Care Medicine.   In "Effects of an Antioxidant-Enriched Multivitamin in Cystic Fibrosis...
Source: bsmmu.edu.bd  Jul 01, 2018  6 years ago
Use of Bio-Kult led to a 69% decrease in abdominal pain, and improved Quality of Life scores.   Results of a new clinical trial confirm the use of Bio - Kult a multi-strain probiotic formula with 14 bacterial strains and 8 billion colony-forming units per day—is safe and superior to placebo in improving GI symptoms in patients with IBS-D (diarrhea-predominant irritable bowel synd...
Source: Siriraj Hospital  Jul 01, 2018  6 years ago
“We believe they will help us improve patients’ safety even further,” Dr Prof Prasit Watanapa, dean of Mahidol University’s Faculty of Medicine Siriraj Hospital, said yesterday. The hopital now serves between 8,000 and 10,000 outpatients daily. Each patient is prescribed more than one medicine on average.    The hospital’s director, Asst Prof Dr Visit Vam...
Source: Samitivej Hospital  Jul 02, 2018  6 years ago
Samitivej Hospital has been awarded the Best Healthcare Medical Services Award for environmental sustainability and organizational development for five consecutive years.   Chairat Panduranamporn, M.D., CEO of Samitivej Public Company, Ltd., represented Samitivej Hospital upon the reception of Thailand Top Company Awards 2017 in the service industry category. The awards were bestowed to com...
Source: Wattanosoth Hospital  Jul 03, 2018  6 years ago
The results achieved by the latest cancer treatments continue to exceed expectations. Examples include: minimally invasive surgery to remove a piece or entire suspicious tumours; chemotherapy to eliminate reproducing cells; targeted therapies to precisely stop cancer from growing and spreading by targeting at specific genes and proteins; and radiosurgery to eradicate cancerous cells.   Assoc...
Staff Writer, TMN  Jul 10, 2018  6 years ago
Dr Greenchart Pornsinsirarak, Yanhee Hospital Dr Greenchart handles more than 10 gender reassignment surgeries a month and in this article, he discusses his work and developments in the local transgender community.   Specialties Plastic Surgery Language Thai, English Medical Education Doctor of Medicine, Chulalongkorn University, Thailand, 1985 Credentials Board of Plastic & Cosmetic S...
Source: eus2018.org  Jul 06, 2018  6 years ago
The 21st International Symposium on Endoscopic Ultrasonography (EUS 2018) will be held in Bangkok, Thailand, on December 1 – 2, 2018. The intensive two-day EUS 2018 program will be comprised of several components including cutting-edge lectures, practical tutorials and round tables, live demonstrations of EUS procedure, leading experts who will present their findings in the field’s mos...
Source: doi.org  Jul 10, 2018  6 years ago
Using high energy ultrasound beams to destroy prostate cancer tumours may be as effective as surgery or radiotherapy, but with fewer side effects. Ultrasound therapy destroys cancer cells in the prostate (illustrated) Prostate cancer is the most common cancer in men in the UK, with around 47,000 cases every year. Treatments include surgery to remove the gland, or radiotherapy, which uses radia...
Source: ucdavis.edu  Jul 09, 2018  6 years ago
Using catheter-based ablation instead of medications alone reduces the risks of death and stroke in patients with the common form of heart arrhythmia known as atrial fibrillation, or AFib, new research from UC Davis physicians shows. Cardiologist Uma Srivatsa led a new comparative outcomes study of patients with atrial fibrillation Ablation is currently only recommended when AFib medications do...
Source: snmmi.org  Jul 08, 2018  6 years ago
A novel nuclear medicine approach is showing great promise for precision treatment of solid tumors in many types of cancer--including lung, breast, pancreas and ovarian in adults and glioma, neuroblastoma and sarcoma in children. The research was presented today at the SNMMI 2018 Annual Meeting, June 23-26 in Philadelphia.   In 2017, researchers from Memorial Sloan Kettering Cancer Cente...
Staff Writer, TMN  Jul 07, 2018  6 years ago
Among patients with breast cancer receiving neoadjuvant or adjuvant chemotherapy, those who underwent scalp cooling were significantly less likely to experience chemotherapy-induced hair loss than those who did not receive scalp cooling, a study published in JAMA has shown.1   Although scalp cooling devices have been used to prevent alopecia caused by chemotherapy, its efficacy has ...
Staff Writer, TMN  Jul 06, 2018  6 years ago
About 10 million Americans suffer from a tremor disorder such as Parkinson's disease. Insightec is an Israeli company backed by the Koch brothers that has developed a focused ultrasound technology to treat tremors. The company is in Phase 3 trials with the FDA for its technology to treat Parkinson's disease. Roughly 10 million people in the United States suffer from some s...
Source: nejm.org  Jul 05, 2018  6 years ago
Using a radial artery graft as a second conduit in coronary artery bypass grafting (CABG) surgery results in a significantly lower risk of heart attack and repeat revascularization at 5 years than using a saphenous vein graft, according to the results of a meta-analysis recently published in The New England Journal of Medicine. Using a radial artery graft instead of a saphenous vein graft i...
Staff Writer, TMN  Jul 04, 2018  6 years ago
A viral immunotherapy using a herpes virus to treat brain tumors has been shown to be safe and well-tolerated in a pediatric study from the University of Alabama at Birmingham. The findings, presented today at the International Symposium on Pediatric Neuro-Oncology in Denver, also showed preliminary evidence of effectiveness in killing malignant tumor cells.   The virus, known as G207, i...
Staff Writer, TMN  Jul 03, 2018  6 years ago
Scientists have developed a swallowed capsule packed with tiny electronics and millions of genetically engineered living cells that might someday be used to spot health problems from inside the gut. This undated photo provided by the Massachusetts Institute of Technology School of Engineering in May 2018 shows a capsule packed with electronics and genetically engineered living cells in Cambridge...
Staff Writer, TMN  Jul 02, 2018  6 years ago
A novel positron emission tomography (PET) imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease. The University of California, Los Angeles (UCLA), study is featured in the June issue of The Journal of Nuclear Medicine.   The U.S. Centers for Disease Contr...
Staff Writer, TMN  Jul 01, 2018  6 years ago
Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for progression of Dupuytren's disease.   Based ...
Source: siemens.com  Jul 10, 2018  6 years ago
Siemens Healthineers is releasing a fresh update to its popular ACUSON Sequoia ultrasound system. The device can image deeper than before while maintaining a high quality output, an important capability for those on the front lines of the obesity epidemic. As an example, using the Deep Abdominal Transducer (DAX) that comes with the Sequoia, clinicians can image targets pretty well as dee...
Source: Spectrum IQ  Jul 09, 2018  6 years ago
Baxter won FDA clearance for its Spectrum IQ infusion system, which has some interesting features designed to prevent the wrong drugs and wrong dosages from being administered. The device connects to the hospital’s electronic medical record system, receiving information from it and sending its own data there for permanent storage.   Baxter’s Dose IQ software within the Spec...
Source: cookmedical.com  Jul 08, 2018  6 years ago
  Cook Medical‘s: Hemospray has been approved by the FDA for performing hemostasis during endoscopic procedures within the GI tract.   It uses the firm’s unique inorganic powder as the active agent, which turns into a gel when it meets blood. The gel stays put and keeps the blood from passing through the treatment area.   Since heat is not used for administering t...
Source: Embolx  Jul 07, 2018  6 years ago
Embolx, a new medical device company out of Silicon Valley, develops microcatheters for arterial endoembolization procedures, and now their next-generation Sniper Balloon Occlusion Microcatheter will be available in the US. The new family of microcatheters shows significant improvement over previous devices, and offers physicians enhanced performance features to make it easier to navigate through ...
FUJIFILM USA  Jul 06, 2018  6 years ago
FUJIFILM is releasing a couple surgical visualization systems that were designed to improve minimally invasive procedures.   The FUJIFILM EL-580FN Ultra-Slim Video Laparoscope System uses the firm’s own Super-Honeycomb CCD sensor to produce high quality images that are sharp and reproduce colors accurately. So-called “Chip on the Tip” high definition digital image...
Source: wustl.edu  Jul 09, 2018  6 years ago
Researchers at Washington University in St. Louis have developed a new technique to deliver genetic material into cells. Called Acoustic Shear Poration (ASP), the method combines ultrasound waves and focused mechanical force to create pores in the cell membrane, allowing genetic material to enter the cell.   Gene therapy holds enormous promise, but getting DNA and RNA to enter cells is a cha...
Source: Google  Jul 04, 2018  6 years ago
Diabetes management is slowly moving away from needles, finger sticks, and insulin pumps that intrude on a person’s life. Now, researchers from the University of Waterloo have developed a novel combination of radar and artificial intelligence (AI) technologies to help people manage diabetes more effectively and detect changes in glucose levels without having to traumatically poke the skin or...
Source: HydrUstent  Jul 03, 2018  6 years ago
Stents are widely used in patient care, but a major complication is infection and, for many types of stents, the need for eventual surgical removal. HydrUStent, a startup based at the University of Minho in Portugal, hopes to improve those limitations.   HydrUStent’s product is a ureteral stent made from a patented material that is antibacterial, homogeneous, and biodegradable. I...
Source: SOAMVAC  Jul 02, 2018  6 years ago
Some post-surgical wounds, including following abdominal surgeries and mastectomies, may require suction drainage to prevent post operative complications due to edema and fluid collections. Suction bulbs have been common for the past few decades, since they don’t require external power and are very simple in design. New technologies can significantly improve this, as batteries have become mo...
Source: Neural Analytics  Jul 01, 2018  6 years ago
Neural Analytics, the Los Angeles based company that won FDA clearance a couple of years ago for its Lucid M1 Transcranial Doppler Ultrasound System, now won another clearance, this time for its NeuralBot robotic ultrasound positioner. The two devices work together and when united will be called the Lucid Robotic System.   The NeuralBot automatically positions the ultrasound probe,...
Staff Writer, TMN  Jul 01, 2018  6 years ago
Amgen announced that the results of two open-label extension (OLE) studies of AimovigTM (erenumab-aooe) in patients with chronic and episodic migraine, respectively, will be presented at the 60th Annual Scientific Meeting of the American Headache Society (AHS) in San Francisco. Results from a one-year study in chronic migraine patients reinforced the established safety and efficacy profile of Aimo...
Staff Writer, TMN  Jul 02, 2018  6 years ago
Amid high demand for GlaxoSmithKline's new shingles vaccine, healthcare providers are running out. Even though the company worked up what it calls a "fair and equitable" process to ship Shingrix doses, two U.S. senators are not satisfied and are urging the drugmaker do more to boost inventory levels. Senators Amy Klobuchar, D-Minn., and Tina Smith, D-Minn., wrote&nbs...
Staff Writer, TMN  Jul 03, 2018  6 years ago
When Roche got Herceptin onto China’s national insurance program, it didn’t expect demand to surge so quickly, overwhelming its production capacity there. Now, to cope with a nationwide shortage, it’s shifting to a different manufacturing site to amp up supplies of the cancer therapy. Roche applied to change Herceptin's existing production site for China to a high...
Staff Writer, TMN  Jul 04, 2018  6 years ago
The US Food and Drug Administration (FDA) has approved updated labeling for Keytruda (pembrolizumab; Merck) and Tecentriq (atezolizumab; Genentech) for patients with locally advanced or metastatic urothelial cancer who are not eligible for cisplatin-containing chemotherapy. The  USFDA is continuing to review Merck's Keytruda and Roche's Tecentriq in pr...
Staff Writer, TMN  Jul 05, 2018  6 years ago
French biotech Abivax’s might be on the verge of HIV cure and prevention discovery, after achieving a significant reduction of viral load patients during the first 28 days of treatment.   The company has announced results from the first group of patients in its most recent phase 2a trial testing the potential HIV cure treatment codenamed ABX464.   The study aimed at acc...
Staff Writer, TMN  Jul 06, 2018  6 years ago
Kratom shares structural similarities with opioid analgesics Opioid-like dependence due to chronic kratom use can be successfully treated with buprenorphine, according to a recent case report published in the Journal of Addiction Medicine. Kratom, an herbal supplement that shares structural similarities with opioid analgesics, has recently grown in popularity  in the West  ...
Staff Writer, TMN  Jul 07, 2018  6 years ago
Among susceptible individuals, statins — which are a common cholesterol-lowering medication — could increase the risk of type 2 diabetes by 30 percent. These new findings are sure to reignite debate. The relationship between statins and diabetes is investigated in a new study. Statins lower cholesterol by reducing its production in the liver. They do this...
Staff Writer, TMN  Jul 08, 2018  6 years ago
Zemdri (plazomicin) Approved by FDA for the Treatment of Adults with Complicated Urinary Tract Infections (cUTI) Achaogen, Inc., a biopharmaceutical company developing and commercializing innovative antibacterial agents to address multidrug resistant (MDR) gram-negative infections, announced that the U.S. Food and Drug Administration (FDA) has approved Zemdri (plazomicin) for adults with complic...
Source: uniqure.com  Jul 09, 2018  6 years ago
The treatment could relieve haemophilia B patients from factor IX replacement drugs UniQure has enrolled the first patient in its registration trial of haemophilia B gene therapy candidate AMT-061 as it tries to keep ahead of a rival project from Spark Therapeutics/Pfizer. The subject is the first out of around 50 subjects that will be recruited into the open-label HOPE-B trial of AMT-061, an a...
Staff Writer, TMN  Jul 07, 2018  6 years ago
IRRITABLE BOWEL SYNDROME is a common condition which can cause bouts of stomach cramps, bloating, diarrhoea and constipation - but a probiotic pill has been scientifically proven to relieve symptoms. IBS is thought to affect up to one in five people at some point in their life, and while there are a host of over-the-counter and home remedies available, a new probiotic supplement has been proven i...
Staff Writer, TMN  Jul 09, 2018  6 years ago
Regenerative therapy is a cell-based technique using stem cells to boost tissue regeneration. Though many different stem cells are used, one of the most promising is fat-derived adipose stem cells.   When tissue is damaged your body will regenerate it by replacing damaged cells through cell growth and division. Your DNA determines how your body knows when and where to regenerate. Similar to...

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