Thailand Medical News

HIV Vaccine Candidate 'Defines Additional Path' for Preclinical Data

Source: The Lancet Jul 22, 2018 6 years ago

Study paves way for better use of primate models in HIV vaccine development The mosaic vaccine HIV-1 vaccine produced comparable immune responses in both humans and rhesus monkeys, a phase I/IIa trial found. In humans, the vaccine was safe and produced antibody responses and T-cell responses, and in monkeys, the vaccine not only produced similar immune responses, but protected again...

Study shows how HIV is shielded from immune attack

Source: Multiple Jul 21, 2018 6 years ago

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host's immune system. Inositol hexakisphosphate fits into the pore structures (pink) of the HIV capsid (teal), and makes the makes the capsid stronger, protecting the genetic material inside. Credi...

Trogazo approved for multidrug-resistant HIV

Source: USFDA & Staff Writer, TMN Jul 19, 2018 6 years ago

A small percentage of patients, some of whom have taken many HIV drugs in the past, have multidrug-resistant HIV, limiting their treatment options HIV naturally mutates and eventually develops resistance to ARVs, which are then rendered ineffective. Patients infected with drug resistant strains of HIV are therefore commonly moved to alternative regimens known as 2nd line drugs. &n...

Lessons from Cancer drug that reactivates HIV can possibly lead to a new approach in HIV Cure

Source: Multiple Jul 18, 2018 6 years ago

People living with HIV must take a combination of three or more different drugs every day for the rest of their lives. Unfortunately, by following this strict treatment plan, they can suffer from side effects ranging from mild dizziness to life-threatening liver damage. However, if they stop taking the drugs, the virus hiding inside their cells can spontaneously resurface. In fact...

UK to Relax Immigration Rules for Non-EU Nurses, Says Report, Opportunities for English Speaking Thai Nurses

Staff Writer, TMN Jul 23, 2018 6 years ago

Britain's planned exit from the European Union is expected to result in restrictions on EU workers coming to the country, which could create further recruitment difficulties for the NHS. The British government will loosen immigration rules to allow more doctors and nurses from outside the European Union to come and work for Britain's National Health Service (NHS), the...

Yanhee Hospital Uses Nursing Aides On Rollerblades To expedite service!

Staff Writer, TMN Jul 22, 2018 6 years ago

In order to expedite service at its hospital, Yanhee Hospital has adopted the practice of getting its nursing aides to use rollerblades to deliver files, test results, x-ray films, prescriptions etc. However TMN staff observed that none were using helmets and safety gear and neither was there specific zones for them in the hospital , so hospital vissitors and patients need to be more careful! &nb...

Liver damage caused by OTC painkillers reduced by this folk remedy

Source: Universiti Putra Malaysia Jul 25, 2018 6 years ago

Over-the-counter painkillers like acetaminophen can damage the liver and cause serious health problems. A new study by Malaysian researchers suggested that compounds from a common fern can protect the liver from toxic acetaminophen. Every day, the liver gets exposed to various substances, many of them toxic. It normally detoxifies and expels those toxic chemicals, but...

High concentration peroxide ingestions can lead to life-threatening ailments and death

Source: University of Colorado School of Medicine Jul 24, 2018 6 years ago

High-concentration peroxide, sometimes promoted in alternative medicine circles for cleanses or as a so-called "natural cure," can lead to numerous life-threatening ailments and death itself, according to a paper published online yesterday in Annals of Emergency Medicine ("Outcomes Following High Concentration Peroxide Ingestions"). "Ingesting high-conce...

Reishi mushroom powder is an effective treatment for mouth ulcers

Source: Hunan Agricultural University Jul 23, 2018 6 years ago

The medicinal mushroom known as “Reishi ” in Japan was the subject of a recent Chinese study on alternative treatments for recurrent oral ulceration (ROU). The results showed that freeze-dried reishi mushroom powder provided effective treatment for the most prevalent mouth ulcer disease in the world. ROU is considered an autoimmune disease. It is a frequent complication fo...

Help for Stress Incontinence

Source: The Journal of the American Medical Association Jul 22, 2018 6 years ago

A new study suggests acupuncture could be effective About half of women ages 40 to 60 experience bladder leaks, or urinary incontinence, according to the American College of Physicians. And a condition called stress incontinence—leaking urine when you cough, sneeze, exercise, or laugh—is one of the most common types. Treatments, which often include drugs and surgery, can be ...

Study Questions the Use of Vitamin D Supplements in Heart Failure Patients

Source: European Heart Journal Jul 20, 2018 6 years ago

Experts urge caution with daily high-dose vitamin D supplements. More is not necessarily better when it comes to the use of vitamin D supplements in patients with heart failure, based on results of a recent study published in the European Heart Journal. Known as the EVITA (Effect of Vitamin D on All-Cause Mortality in Heart Failure) trial, this study looked at the impact of daily ...

Stem Cell Therapy Shows Promise for Patients with Chronic Heart Failure

Source: American Heart Association Jul 19, 2018 6 years ago

Stem cells from umbilical cords may improve heart function and symptoms. Stem cells from umbilical cords show promise as a treatment for heart failure, based on a recent study published in the American Heart Association journal Circulation Research. Known as the RIMECARD trial, this study tested stem cell therapy in 30 patients living with chronic heart failure. The goal was t...

Tea consumption leads to epigenetic changes in women

Source: Uppsala Universitet Jul 23, 2018 6 years ago

Epigenetic changes are chemical modifications that turn our genes off or on. In a new study, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact with cancer and estrogen metabolism. Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consum...

Genes That Increase the Risk of Pancreatic Cancer Identified

Source: Mayo Clinic Jul 21, 2018 6 years ago

Six genes associated with pancreatic cancer have been identified by a research team at Mayo Clinic. The team finds that these genes can be inherited but are also present in patients with no family history of pancreatic cancer. The team recommends genetic testing for all pancreatic cancer patients as the new standard of care. ‘Six genes contain mutations that can be inherited ...

Diet Influences Helicobacter pylori Treatment

Source: Multiple Jul 23, 2018 6 years ago

Scientists examined whether diet may be affecting the success of Helicobacter pylori treatment, and looked at whether nutrients such as cholesterol and omega-3 fatty acids play a role. Helicobacter pylori is a global health issue responsible for gastritis and gastric ulcers. Approximately 50% of the global population suffers from Helicobacter pylori infection, which...

Glutamine supplements show promise in treating stomach ulcers

Source: Beth Israel Deaconess Medical Center Jul 22, 2018 6 years ago

Nearly 30 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resista...

Diverticulitis and Red Meat

Source: Massachusetts General Hospital Jul 21, 2018 6 years ago

This week, meat-eaters receive another diet-based kick in the ribs. A new study, published in the journal Gut, links the consumption of red meat to an increased risk of developing diverticulitis. A recent study uncovers a link between the consumption of red meat and diverticulitis. Diverticulitis is a relatively common complaint that occurs when bulging sacs appear in the lining...

Faulty Vaccines Scandal in China

Source: Reuters, Staff Writer, TMN Jul 23, 2018 6 years ago

Scandal erupts over vaccine safety in China after standards violated A scandal over faulty vaccines in China has sparked anger on social media, underscoring the difficulties regulators face in rebuilding trust after years of food and drug safety scares. The incident is a major blow for Beijing's efforts to push domestically made vaccines and for China's drug regulator, which has been str...

Exact Cause for Irritable Bowel Syndrome Identified

Source: Technischen Universität München Jul 20, 2018 6 years ago

The exact cause of irritable bowel syndrome has been unknown. However, scientists have identified an organic cause of irritable bowel syndromes, reveals a new study. An international team with significant involvement from the Technical University of Munich (TUM) has provided initial clues about the organic triggers of the disease, which affects an estimated one out of six peop...

Can Diabetes cause Parkinson’s disease?

Source: NHS,UK Jul 21, 2018 6 years ago

Studies have shown that people with type 2 diabetes have an increased risk of developing Parkinson’s disease. Men and women with type 2 diabetes may face a significantly higher risk of developing Parkinson's disease later in life, new British research suggests. The finding of a link followed the tracking of Parkinson's diagnoses among millions o...

Diabetes drug with better side-effect tolerance could improve treatment

Source: Multiple Jul 20, 2018 6 years ago

Improved medications for Type 2 diabetes are one step closer thanks to a new discovery reported this week by researchers at the University of Pennsylvania and Syracuse University. By modifying the key ingredient in current diabetes drugs, the researchers produced a compound that was effective for hyperglycemia in animal trials, yet without the most problematic side effects of current drugs. &n...

Reducing HbA1c could lower risk of polyneuropathy in adults with type 2 diabetes

Source: Journal Diabetes Care Jul 19, 2018 6 years ago

Improving HbA1c levels could reduce the risk of diabetic polyneuropathy among adults with type 2 diabetes, research suggests. In a new Danish study, each 1% (11 mmol/mol) increase in HbA1c levels among adults with type 2 diabetes during a 10-year period increased polyneuropathy risk by nearly 66%. The new research used data from the ADDITION-Denmark study, ...

Artery hardening and thickness not affected by stopping hormone therapy

Source: The North American Menopause Society Jul 20, 2018 6 years ago

Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms. A new study connects these two facts to demonstrate little effect of hormone therapy on artery thickness as a precursor to heart disease. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). According...

HIV infection doubles risk of heart disease, global study finds

Source: University of Edinburgh Jul 21, 2018 6 years ago

People infected with HIV are twice as likely to suffer from heart disease, research has found. Analysis of global figures reveals that HIV-associated cardiovascular disease has more than tripled in the past 20 years as more people are living longer with the virus. The greatest impact is in sub-Saharan Africa and Asia Pacific regions, with Swaziland, Botswana and Lesotho particularly ...

Using adrenaline in cardiac arrests results in less than 1 percent more people leaving hospital alive

Source: University of Warwick Jul 20, 2018 6 years ago

A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive—but almost doubles the risk of severe brain damage for survivors of cardiac arrest. The research raises important questions about the future use of adrenaline in such cases and will necessitate debate amongst healthcare professionals, patients and the...

High-Sensitivity Cardiac Troponin in the Evaluation of Possible AMI

Source: Multiple Jul 19, 2018 6 years ago

Introduction High-sensitivity (hs) cardiac troponin (cTn) assays expedite the evaluation of patients with possible acute coronary syndromes (ACS) in the emergency department. Rapid screening protocols with hscTn have been proposed for patients for whom ruling-in or ruling-out acute myocardial infarction (AMI) is the primary issue. These protocols have not included the entire range of patients w...

Novel Biomarker Could Increase Specificity to Diagnosing Rheumatoid Arthritis

Source: University of Tsukuba Jul 22, 2018 6 years ago

While many candidate citrullinated antigens have been identified in rheumatoid arthritis (RA) joints, their involvement in blood serum remains mostly uninvestigated. A new study from the University of Tsukuba-centered set out to explore the expression and commonality of citrullinated proteins in peptide glucose-6-phosphate isomerase-induced arthritis (pGIA) and patients with RA. The team also went...

How the brain plays a role in rheumatoid arthritis inflammation

Source: Multiple Jul 21, 2018 6 years ago

In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain. A new study published in Nature Communications examines this issue. "Rheumatoid arthritis is an inflammatory and autoimmune condition with nasty levels of inflammation that can affect a person'...

Details of Systemic Lupus Erythematosus development uncovered

Source: Multiple Jul 20, 2018 6 years ago

Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation and tissue damage. SLE can involve many organs and systems and has a poor prognosis. It is one of a large group of autoimmune disorders, which occur when the immune system attacks the body's own tissues and organs. Type I interferon (IFN-I), a key protein that regulates the immune system's activity, i...

Using Edited Stem Cells To Fight Arthritis

Source: Multiple Jul 19, 2018 6 years ago

Goal is vaccine that targets inflammation in joints Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, idea...

Kybella: Injectable Double Chin Reduction

Staff Writer, TMN Jul 23, 2018 6 years ago

Fast Facts: Kybella is a nonsurgical injection technique used to reduce excess fat beneath the chin. Each treatment takes about 15 to 20 minutes. It uses a synthetic form of deoxycholic acid. Safety:Kybella was approved by the U.S. Food and Drug Administration (FDA) in 2015. It’s a well-tolerated alternative to surgical procedures such as liposuction. Cost:One Kybella treatment costs b...

What are the risks of CoolSculpting?

Staff Writer, TMN Jul 22, 2018 6 years ago

CoolSculpting, or cryolipolysis, is a nonsurgical body contouring procedure. A plastic surgeon uses a device to freeze fat cells under the skin. Once the fat cells have been destroyed, they are gradually broken down and removed from the body by the liver. Most CoolSculpting sessions take around an hour and cost about Bt 25,000 per treatment area. CoolSculping is a fairly new techniq...

Zydus Cadila gets nod for new Arthritis Drug.

Source: Zydus Cadila Jul 19, 2018 6 years ago

Zydus Cadila gets USFDA approval for arthritis drug,Piroxicam. Zydus Cadila has received final approval from the US health regulator for Piroxicam capsules, used for the treatment of osteoarthritis and rheumatoid arthritis. According to a BSE filing, Zydus Cadila will market Piroxicam Capsules USP in the strengths of 10 mg and 20 mg. The drug will be produced at the group’s manufa...

Targeting IGF-1 hormone may help treat bowel cancer

Source: Institute for Research in Biomedicine , Barcelona Jul 20, 2018 6 years ago

Scientists in Spain have discovered a mechanism that promotes inflammation-related bowel cancer and could offer new treatment targets. Researchers may have found a new treatment target for bowel cancer. The finding concerns the activity of the signaling protein p38 in the myeloid cells of the immune system and that of IGF-1, which is a hormone triggered by p38. Much of the work was con...

Beta-Blockers May Prevent Heart Damage from Chemotherapy

Source: Journal of the American College of Cardiology Jul 20, 2018 6 years ago

Taking heart medication during chemotherapy can help minimize heart damage in breast cancer patients. A common heart medication may help minimize the toxic effects of chemotherapy, based on a clinical trial that tested the use of beta-blockers in breast cancer patients undergoing chemo. Results of the study were recently presented at the American College of Cardiology’s 67th Annual Sci...

MICROBLADING

Staff Writer, TMN Jul 21, 2018 6 years ago

The use of permanent cosmetics dates back thousands of years in history. Microblading, a technique for creating natural looking eyebrows using pigment, has reemerged in popularity in the 21st century, and has rapidly become one of the most popular cosmetic procedures in the United States .However, it has not completely replaced traditional eyebrow micropigmentation techniques: Many peopl...

Review of Fractionated Microneedle Radiofrequency For Skin Rejuvenation

Staff Writer, TMN Jul 20, 2018 6 years ago

One of the most promising new technologies for aesthetic treatments is the combination of two methods previously used individually for skin rejuvenation, microneedling and radiofrequency. This combination therapy, known as fractionated radiofrequency, is effective for improvement in acne and acne scars, as well as fine lines and wrinkles, both on and off the face. It can also be used for all skin ...

The New Electronic and Digital Stethoscopes

Staff Writer, TMN Jul 11, 2018 6 years ago

Our Selection of the best models The world has seen so much growing sophistication in smartphones, internet services, and computers. The good news for health workers is that stethoscopes were not left out. Today, we have electronic stethoscopes. But now that we have several companies and brands producing these techy stethoscopes, it may become a little confusing in choosing what the best ...

Vitamin D Supplementation May Improve Markers of bone turnover in CKD

Source: Institute Of Medical Education and Research, India Jul 13, 2018 6 years ago

Ashok Kumar Yadav, Ph.D., from the Postgraduate Institute of Medical Education and Research in India, and colleagues examined bone turnover among subjects who completed a randomized trial examining the effect of cholecalciferol supplementation on vascular function in patients without diabetes who had CKD stage G3-4 and vitamin D ≤20ng/ml. Participants were randomized to receive two or...

Antioxidant supplements fail to improve sperm quality in infertile men

Source: European Society of Human Reproduction and Embryology Jul 11, 2018 6 years ago

Despite many study results suggesting that antioxidants have a positive effect on abnormal sperm parameters associated with male infertility, a large US clinical trial of 174 couples has found that an antioxidant formulation taken daily by the male partner for a minimum of three months made no difference to sperm concentration, motility or morphology, nor to the rate of DNA fragmentation. Results...

The Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology 2018

Source: Bangkok Joint Congress Jul 11, 2018 6 years ago

The Joint Congress of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology & the Asia Pacific Association of Pediatric Allergy, Respirology and Immunology is coming to the Centara Grand & Bangkok Convention Centre at CentralWorld on 11th – 14th October 2018. With its theme “Novel Therapies, Prevention and Integrated Action: Towards Improved Patient C...

Special UV lamps can kill deadly germs in public places, without harming humans

Source: Columbia University Jul 16, 2018 6 years ago

Researchers from Columbia University have looked into the possibility of using far ultraviolet-C (far-UVC) light as a possible tool for the flu virus’s eradication. According to the researchers, who were led by Dr. David Brenner, continuous low doses of far-UVC light can be enough to kill the airborne flu virus that has been causing problems for th...

Melanoma in the Brain May be Cured By Immune Therapy

Source: Cancer Immunology Research Jul 13, 2018 6 years ago

A type of therapy that harnesses the immune system is giving new hope to people battling a once hopeless cancer -- melanoma that's spread to the brain. Brain Melanoma Development New research involving more than 2,700 U.S. patients is confirming what specialists in the field have long known -- that "checkpoint blockade" treatment can beat back these ...

Mycoplasma Genitalium - A Sexually Transmitted Infection That Could Be the Next Big Superbug

Staff Writer, TMN Jul 12, 2018 6 years ago

The infection can be mistaken for chlamydia, but it's become resistant to traditional antibiotic treatments. Doctors are warning about a sexually transmitted infection that could become the next hard-to-treat superbug, thanks to its increasing resistance to traditional antibiotics. They say that the infection, called Mycoplasma genitalium(also known as M. genital...

Zephyr Endobronchial Valve approved for severe emphysema, USFDA

Source: USFDA Jul 11, 2018 6 years ago

A new device, the Zephyr Endobronchial Valve (Zephyr Valve), has been approved by the U.S. Food and Drug Administration for the treatment of breathing difficulties associated with severe emphysema. Valve has been approved after review of data from trial involving 190 patients with emphysema During a procedure in a hospital setting, the Zephyr Valves are placed into the diseas...

New treatment offers hope for kidney failure and transplant patients with rare disorder

Source: Intermountain Medical Center Jul 16, 2018 6 years ago

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research. This is the first time this new approach has been used successfully anywhere in the world for the disorder, known ...

Robotic surgery is as effective as traditional open surgery in treating bladder cancer, according to a landmark study published in the journal Lancet

Source: Loyola Medicine Jul 13, 2018 6 years ago

Three Loyola Medicine urologists, Marcus Quek, MD, Gopal Gupta, MD, and Alex Gorbonos, MD, are co-authors of the study. First author is Dipen Parekh, MD, of the University of Miami. Loyola is among 15 centers that participated in the nationwide trial of 350 patients, who were randomly assigned to undergo robotic surgery or open surgery to remove cancerous bladders. A...

FDA approves the first drug with an indication for treatment of smallpox

Source: US FDA Jul 16, 2018 6 years ago

The U.S. Food and Drug Administration has approved TPOXX (tecovirimat), the first drug with an indication for treatment of smallpox. Though the World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980, there have been longstanding concerns that smallpox could be used as a bioweapon. “To address the risk of bio...

Tafenoquine Approved by USDA for “Radical Cure” of Malaria

Source: USFDA Jul 13, 2018 6 years ago

An FDA advisory committee voted to recommend approval of single-dose tafenoquine (GlaxoSmithKline) in patients 16 and older for the "radical cure" (prevention of relapse) of malaria, finding both substantial evidence for efficacy and adequate evidence for safety. The vote on the evidence for efficacy was unanimous (13-0), while the evidence for adequate safety also sailed through (12-...

Imbruvica fails to target in B-Cell lymphoma trial

Source: AbbVie Pharmaceuticals Jul 12, 2018 6 years ago

AbbVie and Johnson & Johnson’s Imbruvica has failed to meet its key target in a late stage study assessing its use in patients with treatment-naïve diffuse large B-cell lymphoma. The Phase III DBL3001 study did not show additional efficacy when adding Imbruvica (ibrutinib) to the existing standard of first-line care – a regimen of rituximab, cyclophosphamide, doxorubi...

Phyathai 2 Hospital Heart Center aims for Asia Cardiology Hub

Source: Phyathai 2 Jul 11, 2018 6 years ago

Phyathai 2 Hospital moves forward with their Centers of Excellence policy, invested more than 100 million baht ($3.12 million) into the Heart Center in efforts to optimize the quality of care and outfit with the most cutting edge medical technology to be the foremost cardiac treatment center in Asia. Dr. Thouantosaporn Suwanjutah, Heart Center Director of Phyathai 2 Hospital said th...

Genetic Variants Can Highlight Possible Drugs for Inflammatory Bowel Disease

Source: Wellcome Trusts Sanger Institute Jul 11, 2018 6 years ago

Genetic variants can increasingly be used to connect patients to treatments as well as uncover new therapeutic targets. Jeffrey Barrett, formerly of the Wellcome Trust Sanger Institute, described how prioritizing genome-wide association study results has uncovered drugs that could be used to treat inflammatory bowel disease. Functional Studies on the IBD Susceptibility Gene IL23R I...

Thai FDA joins USFDA and other countries in recalling heart drug, Valsartan due to impurities

Staff Writer, TMN Jul 14, 2018 6 years ago

Thailand's Food and Drug Administration (FDA) on Saturday issued an order to recall some batches of valsartan, a medicine used to control blood pressure and help prevent heart failure, after it was found to contain certain impurities, in doing so, Thailand joins a lists of more than 22 countries that has been doing so in the last 48 hours. The press statements was issued by Dr Wanchai Sattayaw...

Importance of Epigenetics in tracking environmental impact on genomes

Source: Johns Hopkins Medicine Jul 10, 2018 6 years ago

In a review article published in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics. Most people are familiar with genetics, a field of research that focuses on the precise sequence of chemicals that form the ladder-like structure of DNA. However, epigenetics is not as wel...

Massive genome havoc in breast cancer is revealed

Source: Multiple Jul 16, 2018 6 years ago

Researchers using long-read DNA sequencing have made one of the most detailed maps ever of structural variations in a cancer cell's genome. The map reveals about 20,000 structural variations, few of which have been noted before, in just one cell type associated with one form of breast cancer. Long-read sequencing enabled the team to reconstruct in great detail the history of how...

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