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COVID-19 News: The battle against COVID-19 has been ongoing, and one of the significant challenges has been protecting immunocompromised individuals who are at higher risk of severe outcomes from the virus. In response to this critical need, the U.S. Food and Drug Administration (FDA) recently granted emergency use authorization (EUA) for pemivibart (Pemgarda, Invivyd), a monoclonal antibody, as a...
COVID-19 News: The global fight against the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been ongoing for four years, with over 700 million reported cases and 7 million deaths. Despite the development of vaccines and drugs, the rapid mutation of the virus continues to pose a significant public health threat. To address this challeng...
COVID-19 News: Antidepressant usage has seen a significant rise in the United Kingdom, with over 100 daily doses prescribed per 1000 inhabitants. Beyond their primary role in addressing depression, antidepressants have been explored for their potential impact on the immune system, particularly through functional inhibition of acid sphingomyelinase (FIASMA). There has been misinformation spread by ...
COVID-19 News: The ongoing global battle against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to an urgent quest for effective antiviral treatments. The Chinese Academy of Medical Sciences & Peking Union Medical College has been at the forefront of this research, recently revealing a groundbreaking discovery regarding the antiviral potential of carrimycin. ...
COVID-19 News: The ongoing battle against the global COVID-19 pandemic has led researchers to explore unconventional avenues for therapeutic intervention. In a recent development, scientists at the Medical University of Graz in Austria have unearthed compelling evidence suggesting that High-Density Lipoproteins (HDLs) could serve as potent antivirals against SARS-CoV-2 infections. This COVID-19 Ne...
COVID-19 News: In the ongoing battle against the COVID-19 pandemic, the quest for effective antiviral treatments has led researchers to explore the repurposing of existing drugs. Among these, Clofazimine and Arbidol have emerged as promising candidates, demonstrating their efficacy as in vitro SARS-CoV-2 fusion inhibitors. This COVID-19 News report delves into a study conducted at Thomas Jefferson...
COVID-19 News: As the COVID-19 pandemic continues to ravage communities worldwide, the quest for effective treatments remains paramount. Amidst the challenges posed by new variants, limited healthcare resources, and unequal access to medication, repurposing existing drugs has emerged as a promising strategy. One such drug under scrutiny is oseltamivir, commonly known as Tamiflu, traditionally used...
COVID-19 News: Since the onset of the SARS-CoV-2 pandemic in 2020, the quest for effective antiviral therapies has been a focal point of medical research. As witnessed in previous viral outbreaks, such as Influenza and HIV, the development of potent antiviral treatments plays a pivotal role in managing public health crises. Initial hopes were pinned on the repurposing of broad-spectrum antivirals ...
COVID-19 News: In the relentless battle against global public health threats posed by coronaviruses, a groundbreaking study by the University of Bristol has unveiled a promising contender in the form of an HIV drug called Cobicistat. The research covered in this COVID-19 News report, explores the potential of Cobicistat to serve as a broad-spectrum antiviral, capable of inhibiting various coronavi...
COVID-19 News: The COVID-19 pandemic has been a global health crisis of unparalleled proportions, leading to immense mortality and morbidity. Initially, the pandemic brought with it a case fatality rate (CFR) of 2.3%. However, as of 2023, this rate has decreased substantially to a range of 0.05%–0.5%, owing to various factors such as vaccination efforts and increased understanding of the dis...
COVID-19 Antivirals: The COVID-19 pandemic has spurred extensive research into the development of effective antiviral treatments to combat the SARS-CoV-2 virus. Among the many avenues explored, an intriguing discovery has emerged from a collaborative effort involving several prestigious Brazilian institutions: the Federal University of Uberlândia (UFU), São Paulo State University (Une...
COVID-19 Drugs: In the ongoing battle against the COVID-19 pandemic, researchers have been relentlessly searching for treatments that can alleviate the severity of the disease and improve patient outcomes. Sodium glucose co-transporter-2 (SGLT2) inhibitors, known for their cardiovascular and kidney-protective effects in patients with conditions like type 2 diabetes, heart failure, and kidney disea...
COVID-19 Drugs: In the relentless quest to combat the global scourge of COVID-19, researchers around the world have been fervently exploring existing drugs for their potential antiviral properties. Among the contenders, Chlorpheniramine Maleate (CPM), a first-generation H1 antihistamine, has emerged as a promising candidate in the fight against the Severe Acute Respiratory Syndrome Coronavirus 2 (...
Thailand Medical News Team Aug 29, 2023 1 year ago
COVID-19 Drugs: In the midst of the global COVID-19 pandemic, researchers and healthcare professionals worldwide have been tirelessly exploring potential treatment options to combat the devastating effects of the virus. One drug that has recently come under the spotlight for its potential efficacy is Azvudine (FNC), originally developed for the treatment of HIV. This synthetic nucleoside analog ha...
Thailand Medical News Team Aug 26, 2023 1 year ago
COVID-19 News: The global impact of Coronavirus Disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been nothing short of catastrophic. As the world grapples with this ongoing pandemic, researchers and medical professionals continue their relentless pursuit of effective treatments to mitigate the disease's devastating effects. One such treatme...
Thailand Medical News Team Aug 25, 2023 1 year ago
COVID-19 Drugs: The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered unprecedented research efforts to understand the virus's behavior and identify potential treatments. Amid this global crisis, the search for therapeutic agents that can combat the virus has led scientists to explore the properties of 25-hydroxycholesterols (25HC), ox...
Thailand Medical News Team Aug 24, 2023 1 year ago
COVID-19 Drugs: The COVID-19 pandemic has not only challenged the global healthcare system but also revealed a range of unexpected health consequences beyond the acute respiratory symptoms caused by the virus. One of these unforeseen consequences has been the impact on mental health, particularly depressive symptoms experienced by individuals recovering from COVID-19. In light of this, researchers...
Thailand Medical News Team Aug 23, 2023 1 year ago
COVID-19 News: The COVID-19 pandemic, stemming from the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to pose a significant threat to global public health. As new variants of the virus emerge, the efficacy of current treatment options is compromised, underscoring the need for effective antiviral and anti-inflammatory therapies. While various compounds have shown promise i...
Thailand Medical News Team Aug 19, 2023 1 year ago
COVID-19 Drugs: COVID-19, the viral respiratory infection that has swept the globe, has claimed the lives of over 6.9 million individuals worldwide. As researchers continue to grapple with understanding the multifaceted nature of the disease, a recent international study lead by researchers by the University of Zurich that also involved numerous scientists and institutions from around the world ha...
Thailand Medical News Team Aug 19, 2023 1 year ago
COVID-19 Drugs: The ongoing battle against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has driven relentless research to identify effective treatments and interventions.
A pivotal COVID-19 Drugs study conducted by the University of Virginia School of Medicine has illuminated a potential breakthrough in the form of the adenos...
Thailand Medical News Team Aug 19, 2023 1 year ago
COVID-19 Drugs: In a new study conducted by a consortium of esteemed medical institutions including the University of Ferrara-Italy, SS. Annunziata Hospital-Italy, University Hospital of Ferrara Arcispedale Sant’Anna-Italy, and Azienda Unità Sanitaria Locale della Romagna-Italy, the potential life-saving effects of novel antidiabetic drugs, specifically GLP-1 receptor agonists (GLP-1 ...
Thailand Medical News Team Aug 17, 2023 1 year ago
COVID-19 Drugs: The global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) led to unprecedented challenges in healthcare systems and research worldwide. As medical professionals tirelessly sought effective treatments for COVID-19, a groundbreaking study conducted at the University of Maryland in the United States offers new hope.
The study sheds light on the potent...
Thailand Medical News Team Aug 17, 2023 1 year ago
COVID-19 Drugs: In a new study conducted by researchers at the University of Arkansas for Medical Sciences-USA, a concerning link has been identified between the use of the immunomodulatory drug tocilizumab and an increased risk of fungal infections and acute renal failure in critically ill patients battling severe cases of COVID-19. The study sheds light on potential complications associated with...
Thailand Medical News Team Aug 07, 2023 1 year ago
COVID-19 Drugs: The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has posed a significant global health challenge, with millions of people affected and a high mortality rate. In the quest for effective treatments and prophylactic agents, Hydroxychloroquine (HCQ), an antimalarial drug, emerged as a controversial candidate recommended for prophylactic u...
COVID-19 Drugs: The COVID-19 pandemic has been a significant global health crisis, challenging healthcare systems and economies worldwide. Despite advancements in vaccination efforts, effective outpatient treatments for COVID-19 remain crucial, especially for low- and middle-income countries. The acid sphingomyelinase (ASM)/ceramide system has emerged as a potential target for treating COVID-19, w...
Thailand Medical News Team Aug 06, 2023 1 year ago
COVID-19 Drugs: The COVID-19 pandemic has wreaked havoc worldwide, prompting scientists and researchers to explore innovative therapeutics to combat the SARS-CoV-2 virus. While vaccines have been claimed to prevent severe disease, the emergence of new variants and breakthrough infections highlight the need for effective antiviral drugs. In this context, the University of Michigan conducted a groun...
COVID-19-Drugs - N-Acetylcysteine - Sulodexide Jul 27, 2023 1 year ago
Study Finds That Both N-Acetylcysteine And Sulodexide Has Protective Properties On Endothelial Cells After SARS-CoV-2 Infection
COVID-19 Drugs: The world was taken by storm when the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged, causing the coronavirus disease 2019 (COVID-19) pandemic. Beyond its devastating impact on the respiratory system, this novel virus also wrea...
COVID-19 Drugs - Prophylactic - Emerging SARS-CoV-2 Sublineages Jul 21, 2023 1 year ago
Thailand Medical News Exclusive: An existing approved generic drug with an already proven safety track record could be used as a prophylactic and also therapeutic drug against SARS-CoV-2.
COVID-19 Drugs: While new COVID-19 surges are once again wreaking havoc in countries like Japan, South Korea, parts of Brazil and also China, and also in Australia and New Zealand, COVID-19 cases are also ...
COVID-19 Drugs – Aprotinin Jul 16, 2023 1 year ago
Aprotinin Might Emerge As An Antiviral Candidate For SARS-CoV-2 And Even Be An Effective Antiviral To Deal With Impending H5N1 Pandemic!
COVID-19 Drugs: Respiratory diseases caused by viruses, such as influenza and COVID-19, have been a major global health concern, causing millions of deaths and disrupting daily life. However, there is a potential ray of hope emerging in the form of...
COVID-19 Drugs - Suramin - COVID-19 - Endotheliopathy Jul 09, 2023 1 year ago
Besides Preventing Endotheliopathy, Suramin Has Also Shown Inhibitory Effects On The Main Protease Required For SARS-CoV-2 Infection
COVID-19 Drugs: In a recent study conducted by esteemed institutions including the University of South Florida, University of Vermont, Colorado State University, and University of Wisconsin, researchers have discovered that the drug suramin holds tremendous promise ...
COVID-19 News - Metformin -Viral Loads - Randomized Clinical Trial Jun 09, 2023 1 year ago
Cheap, Easily Available Generic Diabetic Medication Shows Promising Potential In Treating COVID-19
COVID-19 News: In a groundbreaking development, a Phase 3 randomized placebo-controlled clinical trial has revealed that metformin, a commonly used medication for diabetes, exhibits significant potential in reducing SARS-CoV-2 viral loads. The trial, known as COVID-OUT, involved a collaboratio...
COVID-19 Drugs - Acyclovir May 09, 2023 2 years ago
COVID-19 Drugs: Drug repurposing has garnered significant interest as a viable alternative to traditional drug development, offering a cost-effective, time-saving, and less risky approach. Amid the ongoing COVID-19 pandemic, the urgent need for therapeutic agents to prevent viral outbreaks has intensified.
Well-established antiviral drugs like acyclovir (Acv) have shown promise in combati...
COVID-19 Drugs - Drug Metabolizing Enzymes And Membrane Transporters (DMETs) May 01, 2023 2 years ago
COVID-19 Drugs: It is coming to light that all strategies with regards to treating COVID-19 has been wrong as many missed out certain critical data that affects the pharmacokinetics and pharmacodynamics of these drugs that have been approved so far by various clueless regulatory agencies across the world.
A new breakthrough study by researchers from University of Toronto-Canada, OneDrug-C...
COVID-19 Drugs - Antihistamines - Cetirizine Apr 26, 2023 2 years ago
COVID-19 Drugs: A groundbreaking study by Spanish researchers from Servicio de Salud de Castilla-La Mancha (SESCAM) in Toledo, Spain, has unveiled the astonishing potential of antihistamines as an early treatment for COVID-19. This discovery could revolutionize our approach to managing the pandemic, reduce hospitalizations, and possibly prevent the spread of the virus among close contacts.
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COVID-19 News - 5-Aminolevulinic Acid (ALA) Apr 09, 2023 2 years ago
COVID-19 News: As the world continues to grapple with the COVID-19 pandemic, a natural amino acid, 5-aminolevulinic acid (ALA), is emerging as a potential antiviral for SARS-CoV-2 infections. This groundbreaking discovery could pave the way for an innovative treatment strategy that targets the angiotensin-converting enzyme 2 (ACE2) receptor, which plays a critical role in the virus's ability t...
COVID-19 Drugs - Methotrexate, Pralatrexate, Trimetrexate Apr 07, 2023 2 years ago
COVID-19 Drugs: Since the outbreak of the COVID-19 pandemic, the scientific community has been tirelessly working to find effective therapeutic strategies to treat SARS-CoV-2-induced respiratory disease. Repurposing approved drugs has emerged as the most rapid, affordable, and efficient strategy for addressing this urgent need. Among the drugs tested for repurposing, methotrexate (MTX), a widely u...
COVID-19 News - Spike Protein Accumulating In Skull Marrow, Brain Meninges And Brain Parenchyma Apr 06, 2023 2 years ago
COVID-19 News: A new study by German and Danish researchers have found the SARS-Cov-2 spike protein accumulating in skull marrow, brain meninges and brain parenchyma while killing brain cells of those who had been exposed to the spike proteins either by infection or by so called mRNA ‘prophylactics.’
The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, has been associa...
COVID-19 News - Endogenous piRNAs Apr 05, 2023 2 years ago
COVID-19 News: In an astounding revelation, a groundbreaking study by researchers from the Polish Academy of Sciences and A. Baitursynov Kostanay Regional University in Kazakhstan has identified a potential game-changer in the battle against the relentless SARS-CoV-2 Omicron variant.
Although the research is still in its preliminary, in silico phase, the astonishing findings are impossibl...
COVID-19 News : Resistance To Clinical Protease Inhibitors Mar 30, 2023 2 years ago
COVID-19 News: Research led by scientist from the University of Minnesota-USA has found that the SARS-CoV-2 coronavirus is evolving to escape all known clinical protease inhibitors. As drug resistance becomes a major issue in the coming CVID-19 onslaughts, a strategy of using a combination of antivirals like that in HIV treatment protocols might be a better solution.
The study also compri...
COVID-19 Drugs - Tucaresol Mar 23, 2023 2 years ago
COVID-19 Drugs: Tucaresol, an is an orally administered antisickling agent which increases the oxygen affinity of hemoglobin is emerging as a potential COVID-19 antiviral and drug to treat SARS-CoV-2 induced lymphopenia and immunodeficiency according to researchers from ChemThera Sciences, a pharmaceutical research company based in Montreal, Canada with a branch in Delaware, United States.
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COVID-19 Drugs - Chlorpromazine And Prochlorperazine Mar 21, 2023 2 years ago
COVID-19 Drugs: Indian researchers after conducting successful animal model drug trials involving hamsters are suggesting that G4-binding drugs, chlorpromazine and prochlorperazine could be repurposed against SARS-CoV-2 infections.
Chlorpromazine, marketed under the brand names Thorazine and Largactil among others, is an antipsychotic oral medication. It is primarily used to treat psychot...
COVID-19 Drugs - Beta-Amido Boronic Acids Mar 12, 2023 2 years ago
COVID-19 Drugs: The COVID-19 pandemic has been a global health crisis unlike any other in recent memory. It has affected millions of people around the world, and finding a cure has become a top priority for researchers and medical professionals. While vaccines have been developed and distributed, there is still a need for effective treatments for those who have already contracted the virus..hence ...
COVID-19 Drugs - Indomethacin Mar 11, 2023 2 years ago
COVID-19 Drugs: Since the beginning of the COVID-19 pandemic, researchers have been exploring various treatment options to combat the virus. One such option is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin. While the use of NSAIDs in COVID-19 treatment remains a topic of debate, several studies have suggested that indomethacin, in particular, could be an effective t...
Long COVID News - Maraviroc - Pravastatin Mar 11, 2023 2 years ago
Long COVID News: A study by American and Costa Rican researchers has found that the drugs Maraviroc and Pravastatin can be used to treat Long COVID.
Maraviroc, sold under the brand names Selzentry and Celsentri, is an antiretroviral medication used to treat HIV infection. It is taken by mouth. It is in the CCR5 receptor antagonist class. It was approved for medical use in the United State...
Long COVID News - Metformin Prevents Long COVID Mar 10, 2023 2 years ago
Long COVID News: In a recent study, researchers from the University of Minnesota-USA investigated the potential benefits of early outpatient treatment of COVID-19 patients with metformin, ivermectin, or fluvoxamine in preventing the development of Long COVID, also known as post-acute sequelae of COVID-19 (PASC).
Their study findings showed that early use of metformin during initial SAR-Co...
COVID-19 News - Untreated COVID-19 Feb 22, 2023 2 years ago
COVID-19 News: A new study conducted by researchers from Brigham and Women's Hospital, Harvard Medical School,Massachusetts-USA and Harvard T.H. Chan School of Public Health-Massachusetts-USA involving a randomized clinical trial has surprisingly found that untreated COVID-19 infected individuals tend to fair better than those treated with Paxlovid (nirmatrelvir–ritonavir) in terms...
COVID-19 News - Gemfibrozil & Lovastatin, Reduces SARS-CoV-2 Neuroinfection Feb 13, 2023 2 years ago
COVID-19 News: A new study by South Korean researchers from Chonnam National University, Korea Research Institute of Chemical Technology along with scientist from University of North Carolina at Chapel Hill-USA has found that SARS-CoV-2 neuroinvasiveness and neuroinfection is governed by cholesterol homeostasis and translational machinery-associated genes! The study team found that brain corticoge...
COVID-19 News -China-Anti-SARS-CoV-2 Drugs - Xiannuoxin - VV116 Feb 08, 2023 2 years ago
COVID-19 News: The Chinese Academy of Sciences at Beijing has announced that China's National Medical Products Administration (NMPA) has conditionally approved tow new drugs to treat COVID-19 after an urgent review and approval under the Special Examination and Approval of Drugs Policy.
These two new novel antivirals are reported to be effective anti-SARS-CoV-2 drugs are Xiannuoxin (s...
COVID-19 News- Ciclesonide - Nsp3 - Nsp4 Mutations Feb 01, 2023 2 years ago
COVID-19 News: Researchers from the Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Murayama Branch, Tokyo-Japan have in a new study discovered that the usage of the inhaled asthma drug ciclesonide is causing frequent occurrences of SARS-CoV-2 NSp3 And Nsp4 Mutations!
Thailand Medical News had in our previous COVID-19 News coverages s...
COVID-19 Drugs - Fluvoxamine Causes Heart Valve Disease Jan 28, 2023 2 years ago
COVID-19 Drugs: Researchers from Columbia University’s Department of Surgery in collaboration with the Pediatric Heart Valve Center at Children’s Hospital of Philadelphia (CHOP), the University of Pennsylvania, and the Valley Hospital Heart Institute have discovered that serotonin can impact the mitral valve of the heart and potentially accelerate a cardiac condition known as degenerat...
COVID-19 Drugs - N-Acetylcysteine or NAC Jan 12, 2023 2 years ago
COVID-19 Drugs: A new study by Italian researchers have found that NAC or N-Acetylcysteine is not only an effective antiviral agent against all of the SARS-CoV-2 variants but also has immunomodulatory properties that can help prevent disease severity.
Thailand Medical News had as early as April 2020 written about the benefits of taking NAC or N-Acetylcysteine supplements to help prevent C...
COVID-19 Drugs - Molnupiravir Dec 24, 2022 2 years ago
COVID-19 Drugs: A new study led by researchers from University of Oxford has found that Molnupiravir that is being promoted by many charlatans and dubious health experts and authorities, does not reduce hospitalization or risk of mortality in vaccinated adults who have contracted COVID-19!
In fact, the overpriced drug that costs more than US$720 for a seven-day course day course has been ...
COVID-19 News - Chlorpromazine Dec 17, 2022 2 years ago
COVID-19 News: A new study by researchers from Inserm (French National Institute of Health and Medical Research) has validated that cholesterol and ceramide lipids facilitate SARS-CoV-2 spike protein-mediated membrane fusion.
The researchers also found that Chlorpromazine (CPZ), a commonly used antipsychotic drug, could be used to inhibit this fusion and also prevent SARS-CoV-2 cellular e...
COVID-19 Drugs - Ursodeoxycholic Acid Dec 15, 2022 2 years ago
COVID-19 Drugs: A new breakthrough study led by researchers from Cambridge University-UK has found that the commonly available cheap generic drug used to treat a type of liver disease ie Ursodeoxycholic Acid (UDCA), could be repurposed to not only treat COVID-19 but also act as an effective prophylactic.
The drug is also not only effective against all existing SARS-CoV-2 variants but also...
Source: COVID-19 Drugs - Diabetics - SGLT-2 Inhibitors Dec 08, 2022 2 years ago
COVID-19 Drugs: A new study by researchers from Fujian Medical University -China, Fujian Provincial Hospital-China and Fujian Academy of Medical Sciences-China has found that diabetics taking SGLT-2i drugs like canagliflozin, dapagliflozin, and empagliflozin prior to contracting COVID-19 have reduced adverse outcomes.
SGLT2i or sodium-glucose cotransporter-2 inhibitors are a class of prescription...