Gastroenterology

New Target For Treatment Of Crohn's Disease Discovered

Source: Thailand Medical News Aug 12, 2019 5 years ago

There is currently no cure for the more than 62 million people in the world living with Crohn's disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body's own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the diseas...

Salt Causes Gastrointestinal Bloating

Source: Thailand Medical News Jun 28, 2019 5 years ago

Researchers from John Hopkins Bloomberg School of Public Health have discovered that the incidence of gastrointestinal bloating was higher in individuals that consumed diets high in salt. Based on analysis of data from the largest clinical trial called DASH-Sodium (Dietary Approaches to Stop Hypertension-Sodium), the team from John Hopkins found that that high sodium intakes increased bloating ...

Singapore Researchers Discover Treatment for Fatty Liver Disease

Source: Thailand Medcial News May 24, 2019 6 years ago

Fatty liver disease is a prevailing disease affecting around 17% of the global population and actually comprises of a variety of specific liver conditions that caused due to existing diabetic or obesity conditions. Very often individuals affected are not even aware in the initial stages till symptoms manifest itself in the later stages of the disease. Its occurrence is more pr...

New probiotic eradicates Crohn's disease biofilms

Source: Case Western Reserve University Apr 04, 2019 6 years ago

Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities—they provide a haven for microbes and are often resistant to antibiotics. A new study describes a specific probiotic mix that could help patients with gastrointestinal diseases avoid harmful biofilms that ...

New therapeutic approach to prevent gastrointestinal disease

Source: Brigham and Women's Hospital Apr 02, 2019 6 years ago

Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical lining of cells in the gut that must allow nutrients into the body while keeping food-borne microbes out—can be compromised during intestinal inflammation and ca...

Drug Sivelestat identified as potential new therapy for liver diseases

Source: Mayo Clinic Mar 23, 2019 6 years ago

Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers. While therapies have been available to treat some forms of liver disease, including hepatitis C and autoimmune hepatitis, options have been more limited for treating portal hypertension, a conditio...

Periodic Fasting Helps In Treatment Of Inflammatory Bowel Disease(IBD)

Source: University of Southern California Mar 06, 2019 6 years ago

USC researchers provided evidence that a low-calorie "fasting-mimicking" diet has the potential to reduce inflammation and repair the gut. Published in a recent edition of Cell Reports, the study reports on the health benefits of periodic cycles of the diet for people with inflammation and indicated that the diet reversed inflammatory bowel disease (IBD) patholo...

New protocol using patients' own modified white blood cells helps treat Crohn's disease

Source: St Thomas' Biomedical Research Centre Feb 17, 2019 6 years ago

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months. Researchers at the NIHR Guy's and St Thomas' Biomedical Research Centre (BRC) developed the technique by studying white blood cells taken from patien...

Researchers discover a type of cell which induces acute inflammatory episodes in bowel diseases

Source: Friedrich-Alexander Universitat(FAU),Germany Feb 05, 2019 6 years ago

More than 4000,000 people in Germany are affected by the chronic inflammatory bowel diseases Morbus Crohn or ulcerative colitis. Patients often suffer from flare-ups, which damage intestinal tissue. In spite of tremendous advances in treating the diseases with medication, the chronic inflammation still cannot be kept sufficiently in check for a number of patients. Until now, little has been known ...

University Of Melbourne Discovers New Stomach Cancer Options

Source: University Of Melbourne Jan 22, 2019 6 years ago

Researchers studying lupus discovered that treatments similar to those already in use to treat melanoma and lung cancer, including immunotherapy, show promise for stomach cancer and may even lead to preventative treatments. Usually the symptoms of stomach or gastric cancer are hard to pick up until it’s too late, making what is a relatively common cancer an often fatal one. Survival rate...

Metabolite Urolithin A (UroA), produced by gut microbiota from berries and pomegranates reduces inflammatory bowel disease.

Source: University of Louisville Jan 10, 2019 6 years ago

Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of people worldwide suffer from IBD in the form of either ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Illustration s...

New Study in Differences in Gut Bacteria will soon result in a Database that can distinguish IBD from IBS

Source: University of Groningen Jan 01, 2019 6 years ago

A team of researchers with members from the Netherlands and the U.S. has found differences in the numbers of gut microbes for patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). In their paper published in the journal Science Translational Medicine the group describes how they sequenced the genome of gut microbes in patients with bowel problems and what they found. ...

Mechanism of infection process of the gastrointestinal bacteria Clostridium Difficile discovered.

Source: VIB (the Flanders Institute for Biotechnology) Nov 25, 2018 6 years ago

Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal barrier of the intestinal tract. The researchers demonstrate the physiological relevance of this process during infection and have published their findings in Nature Commu...

Balancing of “Good” Gut Bacteria by the Immune System helps prevent and treat Inflammatory Bowel Disease (IBD).

Source: Walter and Eliza Hall Institute Nov 06, 2018 6 years ago

Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease (IBD). The study, published in the journal Nature Communications, showed that the increased presence of a protein responsible for sensing infection -- called NLRP1 --...

Fallacies about Diverticulitis challenged by new research

Source: University Of North Carolina Oct 26, 2018 6 years ago

Internists now know that patients who have a sibling with diverticulitis can have three times the risk for the disease, and a low-risk lifestyle decreases risk of incident diverticulitis by half. Nuts, seeds, and popcorn are now OK. Annually in the U.S., diverticulitis is responsible for 2.5 million office visits, 333,000 ED visits, 216,000 hospital admissions, and health care costs of $3.5 bill...

Fibrates Gaining Favor for PBC

Source: University of Miami Miller School of Medicine Aug 28, 2018 6 years ago

With only two treatment options for primary biliary cholangitis, some hepatologists have cast a new eye on an older class of drugs. Fibrates, used for the treatment of dyslipidemia in the United States since the 1970s, had been shown to decrease levels of alkaline phosphatase (ALP), said Cynthia Levy, MD, FAASLD, an associate professor of medicine at the University of Miami Miller School of Medic...

Eat high-fiber foods to reduce effects of stress on gut and behavior

Source: The Journal of Physiology Aug 08, 2018 6 years ago

Eating high fibre foods may reduce the effects of stress on our gut and behaviour, according to new research published in The Journal of Physiology. Stress is a significant health concern and can cause major changes in the gut and in the brain, which can cause changes in behaviour. In recent years there has been growing interest in the link between gut bacteria and stres...

Diet Influences Helicobacter pylori Treatment

Source: Multiple Jul 23, 2018 6 years ago

Scientists examined whether diet may be affecting the success of Helicobacter pylori treatment, and looked at whether nutrients such as cholesterol and omega-3 fatty acids play a role. Helicobacter pylori is a global health issue responsible for gastritis and gastric ulcers. Approximately 50% of the global population suffers from Helicobacter pylori infection, which...

Glutamine supplements show promise in treating stomach ulcers

Source: Beth Israel Deaconess Medical Center Jul 22, 2018 6 years ago

Nearly 30 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resista...

Diverticulitis and Red Meat

Source: Massachusetts General Hospital Jul 21, 2018 6 years ago

This week, meat-eaters receive another diet-based kick in the ribs. A new study, published in the journal Gut, links the consumption of red meat to an increased risk of developing diverticulitis. A recent study uncovers a link between the consumption of red meat and diverticulitis. Diverticulitis is a relatively common complaint that occurs when bulging sacs appear in the lining...

Exact Cause for Irritable Bowel Syndrome Identified

Source: Technischen Universität München Jul 20, 2018 6 years ago

The exact cause of irritable bowel syndrome has been unknown. However, scientists have identified an organic cause of irritable bowel syndromes, reveals a new study. An international team with significant involvement from the Technical University of Munich (TUM) has provided initial clues about the organic triggers of the disease, which affects an estimated one out of six peop...

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