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Genomics and Epigenetics
Featuring all the latest about the newest branch of specialty in the Medical World. From Gene Mapping, new understandings of various Cellular Pathways to breakthroughs in Gene Slicing and Recombinant techniques and even new Gene related treatments.
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Source: Ontario Institute for Cancer Research  Jan 15, 2019
Researchers at the University of Toronto have discovered mutational signatures of tumor hypoxia (low oxygen) in 19 cancer types. The results could be used to help clinicians identify patients who would benefit from higher treatment doses.   In a landmark pan-cancer study  analyzing more than 8,000 tumors across 19 different cancer types, researchers have identified molecular hallm...
Source: University of Michigan  Jan 01, 2019
A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds. It suggests a possible target for prevention strategies, which preliminary work suggests could involve flavonoids derived from cranberries. "We've known for a long time that esophageal adenocarcinoma primarily affects Caucasians and ver...
Columbia University Irving Medical Center  Dec 27, 2018
A new study has found that genes cause about 1 in 10 cases of chronic kidney disease in adults, and that identifying the responsible genes has a direct impact on treatment for most of these patients.  “Our study shows that genetic testing can be used to personalize the diagnosis and management of kidney disease, and that nephrologists should consider incorporating it into the diagnost...
Source: University Of Manchester  Nov 23, 2018
An international study lead by University of Manchester scientists has discovered the identity of genes that predispose people to chronic kidney disease. The discovery is a major advance in understanding of the significantly under-diagnosed disorder which, if left undetected, can lead to failing kidneys that need dialysis or kidney transplantation.    The discovery of 35 kidney &n...
Source: VIB (The Flanders Institute For Biotechnology)   Nov 19, 2018
Mutations in RAS proteins initiate many of the most aggressive tumors, and the search for pharmacological inhibitors of these proteins has become a priority in the battle against cancer. Michail Steklov, Francesca Baietti, and colleagues from the Anna Sablina lab (VIB-KU Leuven Center for Cancer Biology) identified LZTR1 as an evolutionarily conserved component of the RAS pathway. Multiple ...