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Research News: A study team from the Scripps Research Institute, La Jolla-California led by Dr Taishi Kimura, Ph.D., postdoctoral research associate and first author of the study has uncovered an important disease-fighting role for cells called hepatocytes, which constitute most of the liver. It was found that hepatocytes help control infections from common viruses called coxsackieviruses, and pro...
HIV News: University of British Columbia researchers have concluded a new study of which the findings are set to change international treatment recommendations for individuals who are newly diagnosed with HIV, an update that could affect nearly two million people per year worldwide.
The research found that the antiviral dolutegravir is the optimal medication for first-line treatment for i...
Source: COVID-19 Questions Oct 19, 2020 4 years ago
COVID-19 Questions: In the last few days as we were perusing more studies and emerging data, some things really are not adding up and perhaps some other media, researchers or experts can help us with a few answers please.
First, a study dated 2008 makes mention of SARS-CoV-2 and even of a SARS-CoV-3 and this study though was conducted by Chinese researchers in Beijing was catalogued by th...
NEURO-COVID: A new study led by researchers from New York University Langone Health/NYU School of Medicine along with scientists from John Hopkins and University of Utah have found that about one in seven COVID-19 patients has potentially damaging neurological injuries.
It was found that these neurological injuries range from temporary confusion resulting from low body-oxygen levels ...
COVID-19-News: Researchers from IBM Research at T.J. Watson Research Center-New York, have in a new study found that heteroplasmy was more common in COVID-19 patients that actually thought. Heteroplasmy is a condition when a COVID-19 patient is co-infected with more than one variant or lineage of the SARS-CoV-2 coronavirus. The implications from this study finding are massive in terms of treatment...
Source: COVID-19 Research Oct 19, 2020 4 years ago
COVID-19 Research: A new study by researchers from John Hopkins involving young obese mice has found that obesity typically leads to upregulation of ACE2 receptor expression especially in the lungs and trachea, increasing the risk factor for SARS-CoV-2 infection and severity.
In the study, the researchers demonstrated that:
-a) Ace2 expression is elevated in the lung and trach...
Virus News: A frequent medical question since the last century has been why are some individuals more resilient to viruses than others? Possible answers to that question has eluded researchers and scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.
Dr Ed Chuong, an assistant professor of molecular, cellular and develop...
Source: Antibodies-COVID-19 Oct 18, 2020 4 years ago
Antibodies-COVID-19: A new unbiased study by researchers from the University of Montreal has shown that antibody levels drop rapidly in recovering COVID-19 patients.
The study team performed repeated analyses at 1-month intervals on 31 convalescent individuals to evaluate how the humoral responses against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike glycoprotein,...
COVID-19 Latest: Researchers from John Hopkins have identified a compound known as factor D Inhibitor(ACH-145951) that can inhibit the alternative complement immune pathway system that is activated by the SARS-CoV-2 spike protein. Blocking this immune system pathway may stop COVID-19 Infection and prevent severe organ damage.
Animal models demonstrating end-organ protection in C...
COVID-19 News: Researchers from University of Pittsburgh, Cedars-Sinai Medical Center-Los Angeles and Martin Luther University Halle-Wittenberg-Germany have in a new study discovered that a mutation strain of the SAR-CoV-2 called D839Y/N/E that has a unique superantigenic insert in the spike region and is able to generate a hyperinflammatory syndrome reminiscent of toxic shock syndrome (TSS)&...
COVID-19-Infants: French researchers from the Division of Pediatrics and Neonatal Critical Care at “A.Béclère” Medical Centre, Paris Saclay University Hospitals have in a new meta-analysis study involving 176 case reports and past studies found that up to 30 percent of all COVID-19 infected infants had contracted the virus from their mothers.
The study was publis...
Source: Mutations -COVID-19 Oct 17, 2020 4 years ago
Mutations -COVID-19: Biologist and genomic experts from Duke University have identified a number of "silent" mutations in the roughly 30,000 letters of the virus's genetic code that helped it thrive once it made the leap to humans and possibly helped set the stage for the global pandemic. The subtle changes involved how the virus folded its RNA molecules within human cells....
COVID-19 Trends: In the beginning of the pandemic we had a lot of so called non-medical academics and government authorities trying to show off their prowess and ways that the pandemic ‘could be stopped ‘and their theories of flattening the curve with a variety for techniques such as social distancing of only between 1 to 3 meters, etc without first understanding a thing about the viru...
Vaccine-COVID-19: As more studies are showing that antibodies will ultimately only provide short term optimal protection of anything between 10 to 16 weeks and while at the same time other studies are also showing that many AAV (Adeno Associated Virus) vector RNA vaccines that are currently being developed and are in phase 3 trials might actually cause certain adverse effects https://www.thailandm...
Remdesivir: Interim results from the Solidarity Therapeutics Trial, coordinated by the World Health Organization, indicate that remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients.
The study results of the trial are under review for publi...
COVID-19 Winter: Researchers from the University of Utah in a new study has shown that individual particles of SARS-CoV-2 coronavirus undergo structural destabilization at relatively mild but elevated temperatures, strengthening the case for the COVID-19 resurgence in the coming winter.
The research findings are published on a preprint server and are currently being peer-reviewed. https:/...
Source: COVID-19 Research Oct 16, 2020 4 years ago
COVID-19 Research: A new international comparison study of the various coronaviruses and their effects on human host proteins and various human cellular pathways have revealed among many findings that the SARS-CoV-2 coronavirus protein Orf9b actually binds with the human host mitochondria protein TOM 70.
Orf9b of SARS-CoV-2 was found to be localized to mitochondria upon overexpression as ...
Vaccine News: Russia announced two months ago that its AAV (Adeno-associated virus) vector was approved for use despite lacking proper supporting study data and a proper phase 3 trial. In reality to date, the Sputnik V vaccine has been a flop as despite the Russian health authorities not admitting it, local Russian physicians and hospitals reported that that many vaccinated candidates not on...
COVID-19 Crisis: The current COVID-19 pandemic so far has been just a small speck compared of what is really to come and already sadly we can see the stupidity and incompetency of most governments and health agencies so far in terms of how the crisis has been handled in most European countries and the Americas( North and South America)
As of the 16th of October 2020, officially we have mo...
Source: Influenza 2020/2021 Oct 15, 2020 4 years ago
Influenza 2020/2021: Two different studies one by Chinese researchers and another led by British scientists show the high risk involved with sequential infection of influenza followed by COVID-19.
In the first study by Chinese scientist from State Key Laboratory of Virology, College of Life Sciences, Wuhan University-Wuhan, team shows that infection with the Influenza A virus or IAV actua...
Source: COVID-19 Neutralizing Antibodies Oct 15, 2020 4 years ago
COVID-19 Neutralizing Antibodies: A new study by researchers and immunologists from Westlake University, Zhejiang-China, Tsinghua University, Beijing-China and Southern University of Science and Technology, Shenzhen-China has found that human bivalent anti-spike antibodies are more effective in terms of viral neutralization and controlling a SARS-CoV-2 infection in humans.
The study team ...
Antibodies, Antibody test and ADE are a few words that has been in many news articles in the last few months as a result of the ongoing COVID-19 pandemic but many people still do not really have a proper perspective about what they are properly, hence we created this guide with the hope that it might help some of our readers. The summarized guide is not in detailed but just enough for individuals ...
Source: COVID-19 Intranasal Drugs Oct 15, 2020 4 years ago
COVID-19 Intranasal Drugs: North Carolina based clinical-stage biotechnology company Novan, Inc. that specializes in various nitric oxide based therapeutics has announced that its vitro studies involving its NITRICIL™ platform technology that uses berdazimer sodium has demonstrated antiviral effects against the SARS-CoV-2 coronavirus tha causes the COVID-19 disease.
Berdaz...
Source:Airborne SARS-CoV-2 Oct 15, 2020 4 years ago
Airborne SARS-CoV-2 virus can be detected by using dehumidifiers according to a new study by researchers from Maryland University.
The study team presented a simple approach that can potentially provide information about the prevalence of SARS-CoV-2 virus in the atmosphere at any location.
The study findings are published on a preprint server and are currently being peer reviewed. ...
Source: COVID-19 Research Oct 15, 2020 4 years ago
COVID-19 Research: A new study led by Dr Nanshan Zhong and Dr Ling Chen of the National Clinical Research Center for Respiratory Disease in China and Dr Jian Han, Faculty Investigator at the Hudson Alpha Institute in Alabama and founder of iRepertoire have identified a potent biomarker for predicting COVID-19 disease progression.
The study team used sequencing to characterize the immune s...
Source: COVID-19 Asymptomatic Oct 15, 2020 4 years ago
COVID-19 Asymptomatic: A new study led by scientist from Wuhan-China with support from National Institutes of Health, Bethesda-Maryland, have discovered that most COVID-19 asymptomatic individuals tend to have higher levels of lymphocytes especially CD4+ Cells indicating that these T Cells play a crucial role in the COVID-19 disease.
The research findings were published i...
COVID-19- Heart: Researchers from Columbia University Irving Medical Center-New York in a study involving retrospective analysis have found that individuals born with a heart defect who developed COVID-19 symptoms had a low risk of moderate or severe COVID-19 infection.
The study findings were published in the Journal of the American Heart Association. https://www.ahajournals.org/doi...
Source: Antibody Clinical Trial Oct 14, 2020 4 years ago
The Antibody Clinical Trial by Eli Lilly called ACTIV-3 clinical trial involving a combination of antibodies against COVID-19 has been suddenly halted over safety concerns yesterday. No details were furnished to the media or medical community.
A stoppage in trial would typically be because a patient or volunteer showed a serious side effect or became sick, but the company did not cla...
COVID-19 News: German researchers from the University Medical Center-Hamburg, Leibniz Institute for Experimental Virology, German Center for Infection Research, Institute of Neuropathology-Hamburg and the Medical Clinic and Polyclinic-Hamburg have in a new study discovered that the SARS-CoV-2 coronavirus has a high affinity manifesting replicative infection in the carotid arteries of the human hos...
Source: SARS-CoV-2 Antibodies Oct 14, 2020 4 years ago
SARS-CoV-2 Antibodies: A new research recently conducted by scientist from California Institute of Technology (Caltech) which can be described as the first properly detailed SARS-CoV-2 antibody study ever conducted so far has properly identified a series of antibodies that can actually be effective as therapeutics against the COVID-19 disease.
The research findings were published in the j...
COVID-19 Effects: The first documented case of sudden permanent hearing loss as a result of COVID-19 infection has been published in the British Medical Journal (BMJ) although doctors warn that this is not the first isolated case as many more were reported earlier and more such cases are emerging. https://casereports.bmj.com/content/13/11/e238419
Thailand Medical News had already publishe...
Source: COVID-19 Diagnostics Oct 14, 2020 4 years ago
COVID-19 Diagnostics: A new study led by resarchesr from University of Michigan and involved an internation collaboration of various scientist and medical institutions from various countries has identified a protein called suPAR or soluble urokinase plasminogen activator receptor that can be used as a biomarker in blood diagnostics to identify COVID-19 patients who at risk of AKI or acut...
Influenza News: A new study by researchers from Ohio State University Wexner Medical Center have uncovered a therapeutic called MG53 that is derived from a naturally occurring human protein to treat and stop the raging lung inflammation that can contribute to death from an influenza infection.
In animal vivo studies involving mice, all untreated animals given a lethal dose of influenza di...
Coronavirus Latest: Scientist from the University of North Carolina (UNC) Gillings School of Global Public Health have in a study uncovered alarming evidence that humans are susceptible to the new emerging swine coronavirus that has recently been alarming the swine industry.
The new study from the Baric Lab at UNC warns that the coronavirus strain, known as swine acute dia...
Vaccine News: Pharmaceutical giant Johnson & Johnson announced on late Monday that it had temporarily halted its COVID-19 vaccine trial because one of its participants had become seriously sick.
A spokesman for Johnson and Johnson told Thailand Medical News, "We have halted further dosing in all our COVID-19 vaccine candidate clinical trials globally due to a particpant...
Source: COVID-19 Reinfections Oct 13, 2020 4 years ago
COVID-19 Reinfections are on an increase globally with more documented cases emerging not just merely reported incidences.
What’s more alarming is that contrary to claims and preprint studies that were most probably manipulated by the huge pharmaceutical and biotech companies and also by Trump’s administration and the various non-credible American health and regulatory agencie...
Brain-SARS-CoV-2: Swiss, Canadian and Egyptian researchers from the Institute for Regenerative Medicine-Neuroscience Center-Zurich, Division of Neurosurgery, University and University Hospital Zurich, Krembil Brain Institute and Krembil Research Institute-Toronto, Toronto Western Hospital and University of Toronto have in a new study discovered that the SARS-CoV-2 coronavirus uses brain and brain ...
Source: COVID-19 Excess Deaths Oct 13, 2020 4 years ago
COVID-19 Excess Deaths in the United States from March to July 2020 compared to historic norms could be in excess of more than 225,000 deaths with approximately two thirds directly attributable to COVID-19 while additional deaths were indirectly related because individuals avoided emergency care during the pandemic according to a new study by researchers from Virginia Commonwealth University Schoo...
Source: COVID-19 Therapeutics Oct 13, 2020 4 years ago
COVID-19 Therapeutics: According to new research carried out at the University of St Andrews-Scotland, a new inhalation treatment protocol and drug involving synthetic interferons to prevent the spread of COVID-19 is potentially far more effective than currently existing versions of interferons or inhalation protocols.
The Scottish biotech company, ILC Therapeutics based in Newhouse...
COVID-19 Drugs: A new vivo study involving animal models by researchers from Hong Kong University show that the cheap stomach ulcer drug ranitidine bismuth citrate (Tritec) is able to inhibit the SARS-CoV-2 coronavirus.
The study team on Monday announced that the anti-microbial drug used to treat stomach ulcers and bacterial infections has shown promise in combatting the coronavirus...
Remdesivir: The way things are moving in the United States clearly shows that is it now worse than a third world country and nothing American should be trusted anymore as it has completely lost every ounce of credibility. The biggest losers unfortunately are the struggling common American people who we do sympathize with.
The U.S. NIH and its researchers who all have a vested interest in ...
Post COVID-19: Researchers from the University of Melbourne-Australia and Burnet Institute-Australia in a new study have discovered that elevated plasma angiotensin-converting enzyme 2 or ACE2 activity still persists months after SARS-CoV-2 infection. The study team reported that the downregulation of cardiac ACE2 is linked to increased plasma ACE2 activity.
The COVID-19 diseas...
Coronavirus News: A new study by scientist from CSIRO, Australia's national science agency, have alarmingly discovered that the SARS-CoV-2, coronavirus that causes the COVID-19 disease can survive for up to 28 days on common surfaces including banknotes, glass surfaces such as that found on mobile phone screens and stainless steel.
In the study survival rates of the SARS-CoV-2 virus w...
A new study by researchers from the Department of Microbiology and Infectious Disease Center, Peking University Health Science Center-Beijing has alarmingly identified a growing number mutated strains of the SARS-CoV-2 coronavirus that is antibody resistant.
The research findings were published in the peer-reviewed journal: Nature’s
Signal Transduction And Targeted Therapy https://w...
Source: COVID-19 Asean News Oct 12, 2020 4 years ago
COVID-19 Asean News: A team of Indonesian researchers from the Universitas Indonesia in Jakarta has found that the fasting blood glucose (FBG) levels are tied to poor prognosis in COVID-19 patients.
The research findings are published on a preprint server and have yet to be peer reviewed. https://www.medrxiv.org/content/10.1101/2020.09.25.20200774v1
The study team aimed t...
Source: COVID-19 Research Oct 12, 2020 4 years ago
COVID-19 Research: A new study by scientist from the Department of Pathology and Laboratory Medicine at the University of Rochester Medical Center have found that lymphocytopenia (A condition of having a low white blood cell count) prior to exposure to SARS-CoV-2 coronavirus may be associated with an increased risk of dying from COVID-19 disease.
Lymphocytopenia is c...
COVID-19 Updates: A latest research by scientist from Stanford University and Yale University on viral pathogenesis revealed an unexpected new discovery of SARS-CoV-2 viral RNA-binding proteins that protect the host from virus-induced cell death.
Utilizing comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS), the study team identified 309 human host protein...
COVID-19 Help: While tens of thousands are getting infected daily and thousands are dying each day, millions elsewhere are worried and are trying to find ways to help themselves and their loved ones and the only thing that stupid health authorities and incompetent corrupted governments around the world are doing are giving false hopes by an anticipated COVID-19 vaccine that many think will solve t...
Coronavirus News: A new study led by Japanese researchers from the University of Tokyo along with support by scientist from Hiroshima University, Kyoto University, Tokai University, Ulm University Medical Center-Germany, and University of Glasgow have discovered that ORF3b, a protein encoded by the SARS-CoV-2 is responsible for impairing the immune and interferon responses in COVID-19 patients.
...
Source: COVID-19 Medical Devices Oct 10, 2020 4 years ago
COVID-19 Medical Devices: California-based Masimo, a global medical technology company that develops and manufactures innovative noninvasive patient monitoring technologies, medical devices, and a wide array of sensors and a leader in primary pulse oximetry technology has won the U.S.FDA clearance for its Rad-G pulse oximeter, a rugged device developed with the help of The Bill & Melinda...
SARS-CoV-2’s viral proteins according to a new study led by researchers from California Institute of Technology and involving scientist from University of Southern California, University Of Vermont, University of California-Los Angeles, University of Glasgow and Broad Institute of MIT and Harvard, are able to incapacitate human host cells upon invasion and are further able to disarming the c...
COVID-19 Latest: China researchers from the Department of Ophthalmology, General Hospital of the Central Theater Command-Wuhan present yet another case report involving a patient in China who developed an acute glaucoma attack soon after recovering from COVID-19.
In this case study, nucleocapsid protein antigens were detected on the cells of the conjunctiva, iris, and trabecular meshwork ...
Source: Research-COVID-19 Oct 10, 2020 4 years ago
Research-COVID-19: Researchers from Emory University-Altlanta in a new study observing immune cell behavior in COVID-19 patients have discovered that in severe cases of COVID-19, an exuberant activation of immune cells resembling acute flares of systemic lupus erythematosus (SLE), an autoimmune disease is witnessed.
The research findings could lead to new diagnostic tests that could separ...
COVID-19 News: WHO or the World Health Organization has announced a new daily record high in COVID-19 cases confirmed worldwide, with more than 350,766 infections reported in the last 24 hours (for the 8th of October)
The total number of reported global deaths in the last 24 hours was 6,458 only however but this is expected to rise in the next few days as many are in severe conditions in ...
Source: Guide To Myocarditis And COVID-19 By Thailand Medical News Oct 09, 2020 4 years ago
Myocarditis-COVID-19: Of late many have been hearing reading about the devastating effects of the SARS-CoV-2 coronavirus on the hearts of those infected irrespective of conditions they endured ie mild, moderate or severe or even if they were asymptomatic or are recovered.
https://www.thailandmedical.news/news/breaking-covid-19-causing-an-unprecedented-heart-crisis-all-recovered-patients-urged-to...