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The U.S. Food and Drug Administration approved Benlysta (belimumab) intravenous (IV) infusion for treatment of children with systemic lupus erythematosus (SLE) - often referred to as simply "lupus" - a serious chronic disease that causes inflammation and damage to various body tissues and organs. This is the first time that the FDA has approved a treatment for pediatric patients with SLE...
Acutus Medical, a California based company, won European clearance for its AcQMap contact mapping software. The company also won FDA approval for its second generation AcQMap platform .
The technology, used during cardiac ablation procedures, creates volumetric images of the atrial anatomy using ultrasound At the same time, contact-free charge density is used to generate high-definition 3...
Source: University of Texas Health Science Center at San Antonio May 01, 2019 6 years ago
Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced at the Pediatric Academic Societies 2019 meeting in Baltimore, Md. Study coauthor Jane Lynch, M.D., FAAP, professor of pediatrics at UT Health San Antonio, said the drug, liraglutide, in combination with an existing medication, metformin, showed robust effect in treating chi...
Source: Stanford University Medical Center Apr 30, 2019 6 years ago
People suffering from a debilitating and often discounted disease known as chronic fatigue syndrome may soon have something they've been seeking for decades: scientific proof of their ailment.
Researchers at the Stanford University School of Medicine have created a blood test that can flag the disease, which currently lacks a standard, reliable diagnostic test.
"Too often, this diseas...
Source: Proceedings froms ESTRO 2019, Milan Apr 29, 2019 6 years ago
A single high dose of radiation that can be delivered directly to the tumour within a few minutes is a safe and effective technique for treating men with low risk prostate cancer, according to a study presented at the ESTRO 38 conference.
Radiotherapy traditionally involves a series of lower dose treatments that take place over several days or week. The new treatment is called high dose-rate br...
Source: Proceedings froms ESTRO 2019, Milan Apr 28, 2019 6 years ago
For females with hormone-driven breast cancer, adding radiation to hormone therapy might keep their cancer from coming back for up to a decade, a new study finds.
Breast cancer didn't come back in the same breast for 97.5% of women who had radiation therapy plus hormone therapy compared to just over 92% of women who had hormone therapy alone, the researchers said.
In addition, over the stu...
French pharmaceutical giant Sanofi on Friday said the European Medicines Agency had conditionally approved its anti-cancer drug Libtayo, the first drug of its kind to be authorised for use in the EU. The drug, also known as CEMIPLIMAB-RWLC is used for for treatment of Advanced Cutaneous Squamous Cell Carcinoma
The tumour-reducing drug is aimed at patients with the second most common form of ski...
Source: Uppsala University Apr 27, 2019 6 years ago
Many diabetes patients do not only have problems with their insulin, but also with the release of the hormone glucagon. Researchers at Uppsala University have now discovered a regulation mechanism which could provide an opportunity to improve blood glucose control in these patients.
The hormone glucagon, which is released from alpha cells in the pancreas, plays a vital role in blood glucos...
Source: Thomas Jefferson University Apr 26, 2019 6 years ago
A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation—an early indication that the vaccine could activate immune cells to fight colorectal tumors and metastases. Further tests to determine if th...
Source: European Society of Cardiology Apr 25, 2019 6 years ago
Women who take antibiotics over a long period of time are at increased risk of heart attack or stroke, according to research carried out in nearly 36,500 women.
The study found that women aged 60 or older who took antibiotics for two months or more had the greatest risk of cardiovascular disease, but long duration of antibiotic use was also associated with an increased risk if taken ...
Source: American College of Physicians Apr 24, 2019 6 years ago
In the Diabetes Prevention Program (DPP) clinical trial and its long-term follow-up study, among the persons who lost at least 5 percent of their body weight during the first year, long-term maintenance of weight loss was more likely if they had been assigned to treatment with metformin than with placebo or lifestyle intervention. Being older and losing a greater amount of weight in the first year...
Source: Vanderbilt University Medical Center Apr 23, 2019 6 years ago
Diabetes has reached epidemic proportions in Asia and has dramatically increased the risk of premature death, especially among women and middle-aged people, a multinational study led by Vanderbilt University researchers has found.
There is an urgent need to implement diabetes management programs tailored to Asian populations."We found that patients with diabetes are at a substant...
The Thai Food and Drug Administration has announced that Self HIV Test Kits are now available for all to purchase at participating pharmacy outlets.
Dr Tares Krassanairawiwong, the FDA Secretary general also said that individuals that have positive reactive test should immediately contact a doctor or nearby medical hospital of licensed clinic to get appropriate medical advice
There ...
Source: University of Pennsylvania Apr 22, 2019 6 years ago
Whether a wound -- such as a diabetic foot ulcer -- heals or progresses to a worse outcome, including infection or even amputation, may depend on the microbiome within that wound. A new study from the Perelman School of Medicine at the University of Pennsylvania found specific strains of the common pathogen Staphylococcus aureus (S. aureus) are associated with wounds that do not heal. Researc...
Source: Beth Israel Deaconess Medical Center Apr 21, 2019 6 years ago
About one in seven women in the world will develop breast cancer in her lifetime. The vast majority of these cancers depend on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone's effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer to recur o...
Source: Thailand Medical News Apr 20, 2019 6 years ago
From new toxins to new thoughts on duration of effect to micro injections, the toxin market is growing in dermatology.(exclusive interview with Dr . Michael Gold)
The toxin market is growing for aesthetic indications, and patient interest continues to soar. But in addition to a growing market, Dr. Michael Gold, a leading Dermatologists in the US says there are other trends to watch....
Source: The Ohio State University Apr 20, 2019 6 years ago
Researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have developed a novel stroke therapy that, when tested in mice and dogs, has proven superior to the standard of care therapy now offered to patients suffering a stroke.
"We have shown that our drug, which is completely reversible, opens up a blocked blood vessel better than the...
Source: Thailand Medical News Apr 19, 2019 6 years ago
President Trump just signed into law the “Special Registration for Telemedicine Act ” (the Act), requiring the Drug Enforcement Administration (DEA) to activate a special registration allowing physicians and nurse practitioners to prescribe controlled substances via telemedicine without an in-person exam. The DEA has no more than one year to complete the task.
Until now, the f...
Source: Thailand Medical News Apr 19, 2019 6 years ago
As usual, our advice from the team at Thailand Medical News is to focus on the US stock markets rather than the local stocks due to a variety of reasons. The US stock market looks as promising as ever especially when it comes to healthcare and biotech stocks. The U.S. soon will spend nearly 20% of its gross domestic product on health care. This comes as health care costs outpace the rise...
Source: Oregon Health & Science University Apr 19, 2019 6 years ago
A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at Oregon Health & Science University have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord.
The discovery, involving mice genetically engineered to mimic multiple sclerosis, published in the journal&nbs...
Commonly called Bai Bua Bok in Thai, its scientific name is Centella asiatica. Some also call it spadeleaf, Jal Bahmi, Asiatic pennywort, Indian pennywort, or hydrocotyle. Still, its most popular name is gotu kola.
Belonging to the family of carrots, gotu kola is a perennial creeping herb, growing in dark and moist climates of Thailand ,South Africa, Indonesia, Australia, China,...
Source: Thailand Medical News Apr 18, 2019 6 years ago
What can you do to prevent stroke? Age makes us more susceptible to having a stroke, as does having a parent or other close relative who has had a stroke.
You can't reverse the years or change your family history, but there are many other stroke risk factors that you can control—provided that you're aware of them. If you know that a particular risk factor is sabotaging your health...
Source: NIH/National Institute of Allergy and Infectious Diseases,US Apr 18, 2019 6 years ago
Regular infusions of an antibody that blocks the HIV binding site on human immune cells may have suppressed levels of HIV for up to four months in people undergoing a short-term pause in their antiretroviral therapy (ART) regimens, according to a report published online today in The New England Journal of Medicine. Results of the Phase 2, open-label study indicate the antibody, known as UB-42...
Source: AZ Urogynecology and Pelvic Health Center Apr 17, 2019 6 years ago
Interstitial Cystitis (IC) is a medical disorder where patients experience urgent and frequent urination and bladder pain in absence of a bladder infection. IC symptoms can result in poor quality of life with depression, sexual dysfunction, anxiety, sleep dysfunction, and stress.
Typically, patients will suffer with painful urination, bladder pain, urgent or frequent urination and even af...
Source: Thermo Fisher Scientific Apr 17, 2019 6 years ago
Thermo Fisher Scientific, the world leader in serving science, today announced the availability of the Thermo Scientific CEDIA Mitragynine (Kratom) Assay, its newest drugs of abuse test that includes supporting calibrators and controls. The CEDIA Mitragynine (Kratom) Assay can be run on commonly used clinical chemistry analyzers, allowing a broad spectrum of laboratorians to test for the presenc...
Source: University Of Otago Apr 17, 2019 6 years ago
Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that.
Researchers from the University of Otago, New Zealand, and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different in oral cancer tissues compared to the adjacent healthy tissues in...
Source: Stanford Medicine Apr 16, 2019 6 years ago
A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease.
"For the first time in 18 years, we have a therapy for patients with Type 2 diabetes and chronic kidney disease that decreases kidney failure," said Kenneth Mahaffey, MD, professor of medicine at the Stanford University School of Medicine and co...
Source: University of California - San Diego Apr 15, 2019 6 years ago
Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To help keep tabs on inflammation, immune cells employ a molecular machine called the NLRP3 inflammasome. NLRP3 is inactive in a healthy cell, but is switched "on" when ...
Source: American Society of Nephrology Apr 14, 2019 6 years ago
New research reveals that pruritus, or itchy skin, affects a substantial percentage of patients with chronic kidney disease (CKD). The study, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology(CJASN), also indicates which patients are more likely to experience pruritus, and demonstrates that pruritus may affect quality of life and sleep.
In stud...
Source: University of Edinburgh Apr 13, 2019 6 years ago
Researchers say patients should continue to take the drugs, which are commonly prescribed to older men, but warn they may need additional health checks.
The team stressed that current treatment guidelines do not need to change, based on their study of patient health records.
Men with enlarged prostates are commonly prescribed drugs called 5-alpha-reductase inhibitors that reduce the production ...
Source: University Of Michigan Apr 12, 2019 6 years ago
Human papillomavirus infection rates are increasing in women born after 1980 who did not receive the HPV vaccine—putting them at higher risk for HPV-related cancers, according to a University of Michigan study.
While more than 90 percent of HPV-related cancers are preventable, HPV causes more than 40,000 cases of cancer in the United States each year and about 1.8 million cases globally, ...
Source: Pasteur Institute Apr 11, 2019 6 years ago
Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals. Scientists at the Institut Pasteur working in collaboration with the CNRS have demonstrated that a cellular protein is capable of acting as a ...
Source: Thailand Medical News Apr 10, 2019 6 years ago
Dealing with multinational insurance companies can often be a nightmare proposition in Thailand, for expats and tourists alike. Provider networks are often limited. Insured patients must usually pay bills upfront with the promise of reimbursement by the insurer later, which either comes months later or not at all. Necessary medical care is often denied because of technicalities.
Structural F...
Source: The Translational Genomics Research Institute Apr 09, 2019 6 years ago
Hepatocellular carcinoma (HCC) is a long medical name for the most common form of liver cancer, a malignancy whose incidence has nearly doubled over the past decade, making it the fastest growing type of cancer in the U.S., and the third-leading cause of cancer-related death worldwide.
Researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, provide the...
BNH Hospital recently hosted a seminar on the topic of “The Incredible Power of Cell Therapy for pain-free movement” under the cooperation with Avenue Cell Clinic, the leading medical institution in Japan specialising in regenerative medicine with the use of cell treatment.
Nopparat Panthongwiriyakul, MD., Deputy Director of BNH hospital gave an opening speech.&nb...
Source: Thailand Medical News Apr 08, 2019 6 years ago
This article has been specially commissioned by Thailand Medical News to bring about awareness and also create caution about the excessive usage of PPIs (Proton Pump Inhibitors) that is over prescribed currrently in Thailand to treat acid reflux conditions.
A recent landmark population study by US researchers at the University of California -- San Diego has indicated that Proton pump inhibitors ...
Source: University of Michigan Apr 07, 2019 6 years ago
A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial.
The shot, a therapeutic vaccine, injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraep...
Source: McGill University Apr 06, 2019 6 years ago
Researchers have known that inflammation accompanies Alzheimer's disease (AD) brain lesions. Several early studies suggested that "super-aspirins" or Nonsteroidal anti-inflammatory drugs (NSAID) could help avoid the disease. However, after clinical trials showed that NSAIDs don't help patients who already have AD symptoms, doctors wondered whether these drugs could still be...
Source: The London School of Medicine (Blizard Institute) Apr 05, 2019 6 years ago
A recent research found that long-term cotrimoxazole treatment reduces mortality and morbidity in children with HIV by altering their gut microbiome and immune activation.
The finding supports current WHO guidelines, which recommend long-term cotrimoxazole treatment for all HIV-positive people living in areas where malaria and severe bacterial infections are common.
Previous studies have shown...
Source: Case Western Reserve University Apr 04, 2019 6 years ago
Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities—they provide a haven for microbes and are often resistant to antibiotics. A new study describes a specific probiotic mix that could help patients with gastrointestinal diseases avoid harmful biofilms that ...
Source: American Geriatics Society Apr 03, 2019 6 years ago
Acetaminophen (otherwise known by brand names such as Tylenol) is one of the most widely used pain relievers. Almost 60 years of widespread use have made acetaminophen a household product. It's distributed over the counter (OTC) in most countries and judged safe by the scientific community. However, acetaminophen is also one of the most common medications involved in overdoses (the medical ter...
Source: Eko Inc, Berkeley Apr 02, 2019 6 years ago
Eko, a company that makes advanced and innovative stethoscopes that we really like, is now releasing its Eko DUO combination stethoscope/ECG device. The Eko DUO works along with a paired smartphone or tablet, allowing a physician to simultaneously record heart sounds and ECG (single lead) tracings at the point of care. The DUO makes it easy to capture ECG intervals and systolic time intervals...
The U.S. Food and Drug Administration has approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.
"Today's approval of Cimzia fulfills an unmet need for pa...
Source: Thailand Medical News Apr 02, 2019 6 years ago
Siriraj Hospital in Thailand, lead by Dr Vuthinun Achariyapota announced at the recent Society Of Gynecologic Cancers (SGO) Annual Meeting 2019 in Hawaii of a new novel approach of detecting HPV via urine samples.
HPV Virus
The group from Siriraj Hospital initially conducted a study from a sample size of about 96 women. In the study, two methods of detecting high-grade squamous intraepit...
Source: Brigham and Women's Hospital Apr 02, 2019 6 years ago
Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical lining of cells in the gut that must allow nutrients into the body while keeping food-borne microbes out—can be compromised during intestinal inflammation and ca...
Source: France’s Institut Cochin, Paris Apr 01, 2019 6 years ago
A team of researchers affiliated with multiple institutions in France has found that a class of antipsychotic drugs known as phenothiazines was successful in treating a form of meningitis in mice when used with antibacterial agents. In their paper published in the journal Nature Microbiology, the group describes experiments they conducted with meningitis mouse models and what they found.
Me...
SHANGHAI - Following the growth in its scale by 17% last year, Medtec China 2019 has continued its upward momentum trend in terms of the area of exhibition booths commercially available, which has increased by 25%. The overall scale of the event, meanwhile, is up by 21%. So far, the number of new exhibitors, according to the most recent data, has risen to 53. Further, 10 suppliers from New York, U...
Source: University Of California, Santa Barbara Mar 31, 2019 6 years ago
Dementia — an umbrella term for various neurodegenerative conditions involving memory loss and other forms of cognitive impairment — is hard to treat because its causes remain unknown. Researchers, however, are making painstaking progress.
Dr. Kenneth Kosik, the Harriman Professor of Neuroscience at the University of California (UC), Santa Barbara recently led a team of exper...
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Lemongrass, is an herb which belongs to the grass family of Poaceae,1 and is also known as Cymbopogon citratus. It is utilized for its...
Source: American Thoracic Society Mar 30, 2019 6 years ago
Dietary intake of two fatty acids, omega-3 and omega-6, may have opposite effects on the severity of asthma in children and may also play opposite roles in modifying their response to indoor air pollution, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
In "Omega-3 and Omega-6 Intake Modifies ...
Source: Vanderbilt University Medical Center Mar 29, 2019 6 years ago
A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.
The investigators found that in addition to its known ability to block the production of cell growth compounds, the drug DFMO (difluoromethylornithine, known also as Eflornithine and...
Source: American Academy Of Neurology Mar 28, 2019 6 years ago
Women who start their period later, go through menopause earlier or have a hysterectomy may have a greater risk of developing dementia, according to a new study by the American Academy of Neurology. The study found a link between increased risk of dementia and fewer total reproductive years when women are exposed to higher levels of estrogen hormones.
"Since women are 50 percent more...
Source: University of California, Los Angeles Mar 27, 2019 6 years ago
More than half of the people in the world host colonies of a bacterium called Helicobacter pylori in their stomachs. Although it's harmless to many, H. pylori can cause stomach cancer as well as ulcers and other gastric conditions. Doctors tend to prescribe multiple antibiotics to defeat the microbe, but that strategy can lead to antibiotic-resistant superbugs.
Now, a finding by UCLA scient...
Source: Boston University School of Medicine Mar 26, 2019 6 years ago
Researchers have identified a biomarker and a possible new therapy for melanoma.
Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte ( cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells.
"We have now detected the first useful chemi...
Source: UT Southwestern Medical Center Mar 25, 2019 6 years ago
UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.
The proteins -- the transcription factors SIX1 and SIX2 -- activate cellular pathways required for fetal development and later switch to a new role in which they repress these pathways in adult immune system cells.
"This work...