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Source: Thermo Fisher Scientific Nov 11, 2018 6 years ago
Biologics have experienced steady double-digit growth over the last 15 years and now comprise slightly more than a quarter of all New Molecular Entity (NME) FDA approvals. Similarly, EvaluatePharma’s 2017 report on orphan drugs projects that by 2020, six of the 10 best-selling global drug therapies will be biologic sterile injectable drugs. Precision medicine is also on the rise, with the FD...
Source: National News Bureau Of Thailand Nov 11, 2018 6 years ago
The Ministry of Public Health (MOPH) is encouraging the general public to live a healthier lifestyle by choosing foods and drinks certified as healthy alternative foods.
Khun Seree Tuchinda,M.D.
Seree Tuchinda, chief adviser to the public health minister, revealed the MOPH is campaigning for better food safety following a survey which has found many eating behaviors of the people could po...
Source: NIH/National Institute of Environmental Health Sciences(USA) Nov 11, 2018 6 years ago
The National Toxicology Program (NTP) concluded there is clear evidence that male rats exposed to high levels of radio frequency radiation (RFR) like that used in 2G , 3G and 4G cell phones developed cancerous heart tumors, according to final reports released today. There was also some evidence of tumors in the brain and adrenal gland of exposed male rats. For female rats, and male and female mice...
Source: Brigham and Women’s Hospital. Nov 10, 2018 6 years ago
The management of human immunodeficiency virus 1 (HIV), an autoimmune disorder that cripples the immune system by attacking healthy cells, remains a major global health challenge in developing countries that lack infrastructure and trained medical professionals. Investigators from Brigham and Women's Hospital have designed a portable and affordable mobile diagnostic tool, utilizing a cellphone...
Source: University Of Iowa Nov 09, 2018 6 years ago
An unexpected finding that links a structural heart protein to gene regulation following heart stress suggests potential new avenues for developing heart failure therapies.
The work led by University of Iowa heart researcher Long-Sheng Song, MD, focuses on a protein called junctophilin-2 (JP2). Previous work from Song's lab has shown that JP2 is a structural protein that is essen...
Source: University of Edinburgh Nov 08, 2018 6 years ago
A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests.
Scientists say the approach could be used to help doctors choose the best treatments for individual patients and predict which tumours are likely to respond to a particular therapy.
It could help target the use of immunotherapy -- a new ...
Source: Medical University Of South Carolina Nov 07, 2018 6 years ago
Mitochondria are responsible for supplying the cell with energy in the form of ATP through oxidative phosphorylation. There is a group of rare, autosomal recessive disorders, known as Mitochondrial DNA Depletion Syndromes (MTDPS), which causes a significant reduction in mitochondrial DNA (mtDNA) and ATP production. There is no treatment for MTDPS, and it is typically fatal during infancy as a resu...
Source: World Medical Centre Nov 06, 2018 6 years ago
World Medical Hospital recently organized A Health Market; “WMC Healthy Market 2018” at its premises which ran from the 2nd to 4th of November . The market featured a variety of booths and vendors from various aspects of the health industry and was well received by both visitors and patients at its hospital.
Source: Walter and Eliza Hall Institute Nov 06, 2018 6 years ago
Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease (IBD). The study, published in the journal Nature Communications, showed that the increased presence of a protein responsible for sensing infection -- called NLRP1 --...
Source: American College of Cardiology Nov 06, 2018 6 years ago
Women using hormone replacement therapy to relieve the symptoms of menopause faced a lower risk of death and showed lower levels of atherosclerosis, or plaque buildup in the heart's arteries, compared to women not using hormone therapy, according to a single-center study scheduled for presentation at the American College of Cardiology's 66th Annual Scientific Session.
Hormone replacemen...
Source: Federation of American Societies for Experimental Biology Nov 06, 2018 6 years ago
New research identifies potential therapeutic intervention for memory impairment, neuroinflammation, and brain insulin resistance induced by high-fat, high-fructose diet
A study published online in The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active component in green tea, could alleviate high-fa...
Source: University Of Connecticut Nov 06, 2018 6 years ago
Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible.
Syphilis Bacteria
The World Health Organization estimates that 40.7 million people between the ages of 15 and 49 had syphilis in 2017, and about 7.6 million people contract it every year. In the U.S....
Source: Cincinnati Children's Hospital Medical Center Nov 06, 2018 6 years ago
Study points to possible way to predict increased inflammation risk
With an estimated 40 million people in the world dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report in the journal JCI Insights finding an ep...
• The phase III CLL14 study compared Venclexta/Venclyxto in combination with Gazyva/Gazyvaro to standard-of-care Gazyva/Gazyvaro plus chlorambucil
• Data will be submitted to health authorities and presented at an upcoming medical meeting
Basel,
1 November 2018 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the randomised phase III CLL14 study, whi...
Source: University of Missouri-Columbia Nov 05, 2018 6 years ago
In a first study of its kind study, researchers have found that a common chemical consumers are exposed to several times a day may be altering insulin release. Results of the study, led by scientists at the University of Missouri, indicate that the Food and Drug Administration-approved "safe" daily exposure amount of BPA may be enough to have implications for the development of Type 2 di...
Source: University of Sheffield Nov 04, 2018 6 years ago
Vitamin D supplements could help to ease painful Irritable Bowel Syndrome (IBS) symptoms, a new study from the University of Sheffield has found.
Scientists from the University's Department of Oncology and Metabolism reviewed and integrated all available research on vitamin D and IBS -- a condition which affects two in 10 people in the UK.
The study showed a high prevalence of vitamin D def...
Source: Krembil Research Institute Nov 03, 2018 6 years ago
Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks.
A team led by Principal Investigator Dr. Mohit Kapoor, Arthritis Research Director at UHN, published the results today in Annals of the Rheumatic Diseases in a paper titled "microRNA-181a-5p antisense oligonu...
National News Bureau Thailand Nov 03, 2018 6 years ago
The many tourists who enjoy winter's cool breezes should beware of malaria and typhus, especially those who like to pitch their tents in the great outdoors.
Typhus
Dr. Surachai Chokekanchitchai, the Director of Uthai Thani Hospital, recently noted that tourists pitching tents in the woods run the risk of getting bitten by mosquitoes, which in Thailand can include anopheles mo...
Source: University of Eastern Finland Nov 03, 2018 6 years ago
Scientists have discovered new compounds that may explain whole grain health benefits, reports a new study led by the University of Eastern Finland. A high intake of whole grains increased the levels of betaine compounds in the body which, in turn, was associated with improved glucose metabolism, among other things. The findings shed new light on the cell level effects of a whole grain-rich diet, ...
Source: Cedars-Sinai Medical Center Nov 02, 2018 6 years ago
A team led by a Cedars-Sinai physician-scientist has discovered a biomarker -- a protein found in the blood -- for the most common type of heart failure, a new study published today in JAMA Cardiologyshows. Discovery may aid doctors in diagnosing at-risk patients before symptoms appear.
Heart failure with preserved ejection fraction (HFpEF) affects more than 6.5 million Americans each year...
Source: British Medical Journal Nov 02, 2018 6 years ago
A predominantly plant-based or vegan diet may be best for keeping type 2 diabetes in check, not least because of its potential impact on mood, suggests a systematic review of the available evidence, published in the journal BMJ Open Diabetes Research & Care.
This diet is associated with improved psychological wellbeing, a reduction in some of the known risk factors for typ...
Source: Cerebrotech Medical System Nov 01, 2018 6 years ago
A portable, visor-like device has shown potential for detecting emergent large-vessel occlusion with 92% accuracy in patients who may have had a stroke. The researchers suggest that the diagnostic device could be readily accessible to emergency personnel and in public spaces in the same way a defibrillator is available for treating heart attacks.
Researchers and clinical investigators Med...
Source: University of California Nov 01, 2018 6 years ago
Researchers are investigating other antiretrovirals, antibodies, injectables, implants, vaginal rings, vaginal films and other products
Oral pre-exposure prophylaxis (PrEP) based on tenofovir disoproxil fumarate /emtricitabine (Truvada)has set a high bar for prevention effectiveness, but a range of alternative PrEP products are in development, Raphael Landovitz of the University of...
Source: Brunel University London Nov 01, 2018 6 years ago
A shift in glucose metabolism hails progression from liver cirrhosis to liver cancer, finds a new study
Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments. Published in Frontiers in Cell and De...
Source: McMaster University Nov 01, 2018 6 years ago
While exercise buffs have long used protein supplements to gain muscle, new research from McMaster University suggests one protein source in particular, whey protein, is most effective for seniors struggling to rebuild muscle lost from inactivity associated with illness or long hospital stays.
The study, published online in The American Journal of Clinical Nutrition, compared the impa...
Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract infections (UTIs) caused by several multidrug resistant Gram-negative bacteria.
The findings, published in The Lancet Infectious Diseases, indicated that patients treated with the siderophore-based drug...
Source: University of Otago Nov 01, 2018 6 years ago
University of Otago researchers have used high-resolution electron microscopy images to reveal how an anti-cancer virus interacts with tumor cells, increasing its potential to save lives.
Seneca Valley Virus (SVV), a newly discovered virus which infects cancer cells but not normal tissue, has become a main research project in the New Zealand laboratory of Dr Mihnea Bostina, Academic Director of ...
Merck Today Announced The 24-Week Results Of The Phase II Study Of Evobrutinib In Patients With Relapsing Multiple Sclerosis (Rms) In Berlin, Germany.
Evobrutinib
First Bruton’s Tyrosine Kinase inhibitor (BTKi) demonstrating clinical proof-of-concept in relapsing multiple sclerosis (RMS)
Study met primary endpoint demonstrating significant reduction in Gd+ enhancing T1 lesions on MRI wi...
Data show Lokelma maintained normokalaemia during days 8-29 of the maintenance phase in patients from four Asian countries
AstraZeneca today presented the results from the HARMONIZE Global Phase III trial, which investigated the safety and efficacy of Lokelma (sodium zirconium cyclosilicate) vs. placebo in patients with hyperkalaemia in Japan, Korea, Taiwan and Russia. The resul...
Source: TCIJ (Thai Civil Rights and Investigative Journalism) Oct 29, 2018 6 years ago
The president of the Nursing Union of Thailand (NUOT) led a delegation to meet with the Thai Parliament’s Extraordinary Commission on the Draft Amendment of Compensation Fund Act .NUOT’s President, Ms Mullika Lunnajak, provided information on the actual experiences of nurses and other workers employed at state hospitals and workplaces across Thailand. Civil servants and other types of ...
Source : University of California Oct 29, 2018 6 years ago
Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.
Mallotus oppositifolius
The herbal medicine, a leaf extract from the shrub Mallotus oppositifolius, was previously...
Source: Dermatology Dept, University Of California Oct 29, 2018 6 years ago
Autologous treatment with injected platelet-rich plasma (PRP) yielded substantial improvement in hair count and shaft thickness in patients with androgenetic alopecia (AGA) after three monthly treatments, in a study that compared two treatment regimens.
PRP is gaining popularity because of its efficacy in stimulating fibroblast proliferation, triggering the production of collagen and e...
Source: National News Bureau Of Thailand Oct 29, 2018 6 years ago
The Ministry of Public Health has instructed all hospitals under it to prescribe medications appropriately, and lower antibiotics use by 20%, by 2021.
In 2019, the ministry will decrease antibiotic prescriptions for upper respiratory tract infections, acute diarrhea, open wounds and normal labor, to decrease drug resistant risks. The ministry instructed the hospitals to prescribe me...
Source: University of East Anglia Oct 26, 2018 6 years ago
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.
Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat. The main types of omega 3 fatty acids are; alphalinolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaeno...
Source: University Of North Carolina Oct 26, 2018 6 years ago
Internists now know that patients who have a sibling with diverticulitis can have three times the risk for the disease, and a low-risk lifestyle decreases risk of incident diverticulitis by half. Nuts, seeds, and popcorn are now OK.
Annually in the U.S., diverticulitis is responsible for 2.5 million office visits, 333,000 ED visits, 216,000 hospital admissions, and health care costs of $3.5 bill...
Source: Lund University in Sweden Oct 26, 2018 6 years ago
By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease. The findings are published in the scientific journal Cell Metabolism.
VDAC1 Protein
The researchers at Lund...
Roche announced that the US Food and Drug Administration (FDA) has approved Xofluza™ (baloxavir marboxil) for the treatment of acute, uncomplicated influenza, or flu, in people 12 years of age and older. Xofluza is a first-in-class, single-dose oral medicine with a novel proposed mechanism of action that inhibits polymerase acidic endonuclease, an enzyme essential for viral replication. [1-2...
National News Bureau Of Thailand Oct 25, 2018 6 years ago
The Ministry of Public Health (MOPH) has a policy to reduce the number of deaths from three major causes.
The MOPH Permanent Secretary, Sukhum Kanchanaphimai, said in 2019, the MOPH has a policy to reduce the number of deaths from three major causes of deaths in Thailand namely cerebrovascular diseases, Septicemia and traffic accidents.
The MOPH Permanent Secretary, Sukhum Kanchanaph...
Source: National News Bureau Of Thailand Oct 25, 2018 6 years ago
Chulalongkorn University’s faculty of medical science has successfully produced a cancer treatment of equivalent efficacy to internationally available drugs in a test tube, and has committed to developing it over the next eight years to serve as an affordable choice for Thai citizens.
Dr. Trairak Pisitkul,Head of Chulalongkorn University’s Systems Biology Center
The rese...
Samitivej Hospital wins the ‘Most Improved Hospital in Thailand’ at the international Asian Hospital Management Awards 2018
Samitivej Hospital has strengthened its reputation among the international community after it was presented with ‘The Most Improved Hospital in Thailand’ award at the AHMA Awards 2018, with Chairat Panthuraamphorn, M.D., CEO of Samitivej and BNH hos...
Source: The University of Manchester Oct 25, 2018 6 years ago
What causes Alzheimer's disease? The answer could be right under our noses, says leading expert Professor Ruth Itzhaki. Her latest paper presents a lifetime of research evidence that the herpes virus responsible for cold sores can also cause Alzheimer's -- and new data which show antiviral drugs drastically reduce risk of senile dementia in patients with severe herpes infections. The revie...
The newest once-daily, all-in-one HIV combination pills can maintain undetectable viral load for two years and counting, according to a set of studies presented at ID Week 2018 this month in San Francisco.
Two phase 3 clinical trials showed that most people who took the bictegravir-based Biktarvy co-formulation or the doravirine-based Delstrigo pill for first-line t...
Source: Wellcome Trust Sanger Institute Oct 25, 2018 6 years ago
Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the Cancer Gene Census. Describing all genes strongly implicated in causing cancer, the Census also describes how they function across all forms of this disease. Reported in Nature Reviews Cancer, the resource catalogues over 700 genes, to help scientist...
Source: University of California Oct 25, 2018 6 years ago
Running low on oxygen is a major danger for any of your body's tissues, but the heart is particularly sensitive to such hypoxic conditions, which can lead to long-term tissue damage or even heart attacks.
In new studies conducted at UC San Francisco, a novel oxygen-delivery therapeutic restored the function of oxygen-starved heart tissue in an animal model of global hypoxia. Unlike...
Source: Charité - Universitätsmedizin Berlin Oct 24, 2018 6 years ago
An international research group led by Charité -- Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis. The drug is effective in patients with moderate to severe forms of the disease who have shown an inadequate response to conventional disease modifying drugs. Results from this research have been published in The Lancet.
ABBVIE: Upadacitinib ...
Source: Massachusetts General Hospital Oct 24, 2018 6 years ago
A group of Massachusetts General Hospital (MGH) investigators is proposing that targeting immune checkpoints -- molecules that regulate the activity of the immune system -- in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). In their review artic...
Source: Journal of Controlled Release Oct 24, 2018 6 years ago
Houston Methodist scientists have developed a nanodevice to deliver immunotherapy without side effects to treat triple-negative breast cancer. Inserted straight into a tumor, this nanofluidic seed makes it possible to deliver a one-time, sustained-release dose that would eliminate the need for patients to undergo several IV treatments over time.
MAGE: SMALLER THAN A GRAIN OF RICE, ...
Source: University Of Vienna Oct 24, 2018 6 years ago
Researchers monitored a group of participants from 8 countries across the world with results showing that every single stool sample tested positive for the presence of microplastic and up to 9 different plastic types were identified.
Microplastics have been found in the human food chain as particles made of polypropylene (PP), polyethylene-terephthalate (PET) and others were detected in human sto...
Source: Zacks Equity Research Oct 23, 2018 6 years ago
October traditionally has been a weak month for stocks. However, biotech stocks have shown significant resilience so far this year, with the iShares Nasdaq Biotechnology ETF (IBB) gaining 11.5% year-to-date (YTD). Additionally, the broader Health Care Select Sector SPDR ETF (XLV) has risen 15.1% YTD, better than the S&P 500’s increase of 9% during the same period.
Health problems...
Source: G.A.M. Legal Alliance, Thailand Oct 18, 2018 6 years ago
A recent article in Forbes talked about the medical tourism boom in Thailand and the advantages of seeking medical treatment here: low costs, high-quality treatment, and well-trained physicians. Thailand has long since joined emerging countries like India that offer an inexpensive solution to rising healthcare problems.
However, even state-of-the-art facilities and top doctors cannot guarantee th...
Source: Stanford University Medical Center Oct 16, 2018 6 years ago
The most common source of a bloodstream infection acquired during a hospital stay is not a nurse's or doctor's dirty hands, or another patient's sneeze or visitor's cough, but the patient's own gut, Stanford University School of Medicine investigators have found.
Most patients who spend longer than a few days in a hospital acquire infections. In particular, upward ...
Metastatic breast cancer is cancer that has advanced and spread beyond the breast and regional lymph nodes to other parts of the body. Around 20–50% of patients diagnosed with primary breast cancer will develop metastatic disease and up to 19% of patients with breast cancer already had metastatic disease when they were first diagnosed.
Treatments for metastatic breast cancer aim to allevia...
Medical Spheres Inc, a New York based company with operations in America, Canada and also Europe through its office in London, is proud to announce its aggressive expansion plans in the Asia-Pacific Region for the next 5 years.
For its Medical and Pharmaceutical Industry based Marketing, Branding, PR, Research and Event Services Division, it started its Asia-Pacific expansion with the opening of ...
Lifestyle Brand Introduces Innovative Customized Health Experience to Combat Nutritional Deficiencies
SAN FRANCISCO, Oct. 3, 2018 /PRNewswire/ -- Baze, a lifestyle brand focusing on personalized health, has launched the Baze Starter Kit, a simple and affordable, fully-tailored experience designed to combat nutrient deficiencies. The Baze Starter Kit combine...
Source: American Diabetes Association Oct 02, 2018 6 years ago
Having type 1 diabetes is not associated with an increased risk of developing a hearing impairment, research has found.
Scientists compared 1,150 people with type 1 diabetes with 283 of their partners who did not have the condition - the results indicated no overall difference in hearing ability in both groups.
Type 1 diabetes does not impact hearing loss study suggests
However, the findin...