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Source: NeuroCOVID - SARS-CoV-2 - Microglia Nov 08, 2022 2 years ago
NeuroCOVID: A new study by researchers from the University Of Queensland- Australia has revealed that the spike proteins of the SARS-CoV-2 coronavirus induces NLRP3 inflammasome activation in human microglia!
The study findings have enormous implications and bearings on the long term NeuroCOVID complications in individuals exposed to the novel coronavirus and also potential increase in cu...
Source: Medical News - COVID-19 Research - Cystitis Nov 08, 2022 2 years ago
A cohort study by medical researchers from the Department of Urology, Oakland University William Beaumont School of Medicine, Beaumont Hospital-Royal Oak, Michigan – USA has found that COVID-19 increases the incidence of cystitis, overactive bladder and other urinary issues!
Shockingly, the research findings showed that symptomatic SARS-CoV-2 infection was associated with a three ti...
Source: COVID-19 Drugs - Fluvoxamine Nov 07, 2022 2 years ago
COVID-19 Drugs: A new study by researchers from Intermountain Medical Center; Stanford, Salt Lake City-Utah, USA has confirmed that the usage of selective serotonin reuptake inhibitors (SSRIs) such as Fluoxetine or Fluvoxamine does not reduce COVID Severity.
Shockingly, the study findings showed that hospitalization and death were significantly greater in the those taking SSRIs such as Fluoxetine...
Source: COVID-19 News - Persimmon Candies As Antivirals Against SARS-CoV-2 Nov 06, 2022 2 years ago
COVID-19 News: A Japanese study team compromising of researchers from Nara Medical University, National Hospital Organization Nara and Kio University have developed candies from tannins of persimmon as antivirals against the SARS-CoV-2 virus.
According to the study team, inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the mouth has the potential to reduce t...
Source: health News - RSV Infections Surge Nov 05, 2022 2 years ago
Health News: RSV or respiratory syncytial virus infections are currently rising across the globe along with Influenza and also COVID-19 infections. While to date, most of the hard hit are children, it is a fallacy to assume that RSV does not affect adults. In fact, not only can adults contract the virus but usually when adults get it, it is often severe.
Research has shown that RSV infect...
Source: Pharma News - Gepotidacin - UTIs Nov 05, 2022 2 years ago
Pharma News: Pharma giant, GSK has developed a new antibiotic called Gepotidacin that could fight tough-to-treat drug resistance urinary tract infections (UTIs).
Phase 3 clinical trials proved to not only be successful but demonstrated the efficacy of the drug beyond the researchers’ expectations that the trials ended earlier than expected.
https://www.gsk.com/en-gb/media/press-rele...
COVID-19 News - Long COVID - Viral Persistence Nov 04, 2022 2 years ago
COVID-19 News: Researchers from the Institute of Molecular and Cell Biology (IMCB) at the Agency for Science, Technology and Research (ASTAR) - Singapore, Long Covid Autonomous Comm unities Together Spain (Research Group) Madrid -Spain, Vetcare Hospital Veterinario Madrid -Spain, Singapore General Hospital, Cancer Science Institute of Singapore and the Singapore Immunology Network (SIgN) presented...
Source: Vaccine News- BA.5 Bivalent Booster Nov 04, 2022 2 years ago
Vaccine News: A new study by researchers from the Sealy Institute for Vaccine Sciences at the University of Texas Medical Branch Galveston - USA and also from the Department of Biochemistry and Molecular Biology along with the Department of Pathology at the University of Texas Medical Branch, Galveston – USA have found that the new BA.5-Bivalent-Booster elicits better neutralization than par...
Source: COVID-19 Neuroinflammation Nov 04, 2022 2 years ago
COVID-19-Neuroinflammation: A new study by researchers from the University of California- Davis, USA involving rhesus macaques (Macaca mulatta) of Indian origin has demonstrated that SARS-CoV-2 infections induces neuroinflammation.
Graphical Abstract
The study findings in a non-human monkey models have strong implications of the effects of SARS-CoV-2 on the brains of humans.
The SA...
Source: Medical News - TYK2 Gene Prevents COVID-19 Severity Nov 04, 2022 2 years ago
Researchers from King’s College London - United Kingdom have discovered that the gene TYK2 that is associate with systemic lupus erythematosus (SLE) provides protection against SARS-CoV-2 infections and also prevents COVID-19 severity but increases the risk for autoimmune diseases.
The study team observed a correlation between the genetic associations with severe COVID-19 and those ...
Source: SARS-CoV-2 News - Cyclophilin-A Nov 03, 2022 2 years ago
SARS-CoV-2 News: South Korean researchers from Chungbuk National University, Shin Ansan University and Jeonbuk National University have found that the human host protein Cyclophilin-A plays a role in in aiding SARS-CoV-2 infections!
Cyclophilins (CYPs) are a family of proteins named after their ability to bind to ciclosporin (cyclosporin A), and function as immunosuppressants. They are fo...
Source: Health Supplements - Inulin Nov 03, 2022 2 years ago
Health Supplements: Researchers from Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York – USA have found that the health supplement Inulin that is often promoted for weight loss or a rich-fiber source suitable for diabetic and those with high cholesterol and triglyceride levels or even a preb...
Source: Medical News -Vaccines Driving Mutations Nov 03, 2022 2 years ago
Researchers from Peking University, Beijing - China and the Changping Laboratory, Beijing- China are warning that imprinted SARS-CoV-2 humoral immunity is inducing convergent Omicron RBD evolution.
Thailand Medical News would like to add that in November 2020, when we covered a Harvard study and warned that the adoption and extensive usage of monoclonal antibodies and vaccines would lead ...
Source: COVID-19 Supplements - Vitamin D Nov 02, 2022 2 years ago
COVID-19 Supplements: Scientists from the College of Health Sciences, University of KwaZulu-Natal, Durban - South Africa have found that SARS-CoV-3 infections can lead to epigenetic changes in the human host immune response genes and that these epigenetic changes can be prevented or reversed by Vitamin D!
The ongoing COVID-19 pandemic has to date infected more than 636 million and killed ...
Source: Medical News - Vimentin Co-Receptor For SARS-CoV-2 Nov 02, 2022 2 years ago
A new study by researchers from Aix Marseille University -France has discovered that Vimentin, a host structural protein is also an important ACE2 Co-Receptor for SARS-CoV-2 in epithelial cells!
Thailand Medical News had also reported on a previous American study that also found that Vimentin plays a role in SARS-CoV-2 infections.
https://www.thailandmedical.news/news/breaking-boston-univ...
Source: COVID-19 Drugs - Memantine - NMT5 Nov 02, 2022 2 years ago
COVID-19 Drugs: Researchers from Scripps Research Institute - California-USA have created a variant of the generic drug Memantine which is an Aminoadamantane compound, to inhibit the SARS-CoV-2 virus entry by targeting the ACE2 receptors.
Prevention of infection and propagation of the SARS-CoV-2 coronavirus is a high priority in the ongoing COVID-19 pandemic which is expected to get worse...
Source: Medical News -SARS-CoV-2 Induced Dysbiosis Nov 01, 2022 2 years ago
A new study led by researchers from New York University Grossman School of Medicine – USA along with scientist from Yale University -USA has found that SARS-CoV-2 infections causes gut microbiome dysbiosis which in turn increases the risk for bacterial infections!
Despite numerous studies showing that microbial populations in the gut microbiome are associated with COVID-19 severity,...
Source: COVID-19 News - New SARS-CoV-2 Variants & Sub-lineages ie BQ.1.1.10. XBB.1, BA.4.6.3, CH.1.1 Nov 01, 2022 2 years ago
COVID-19 News: Researchers are sounding alarms that while the SARS-CoV-2 coronavirus is evolving rapidly and spawning a variety of variants and sub-lineages, some of these such as the BQ1.1.10, XBB.3, BA.4.6.3 and CH.1.1 sub-lineages are literally taking immune evasion to a whole new level. It is warned that it is only a matter of time before any form of natural immunity or immunity induced by any...
Source: Long COVID - Thyroid Dysfunction Nov 01, 2022 2 years ago
Long COVID: In the early part of 2022, Thailand Medical News covered a report by a British lab that there an on uptick in the number of patients being diagnosed with thyroid issues and that it was speculated that the Omicron variants and its sub-lineages could be responsible for these.
https://www.thailandmedical.news/news/breaking-cso-from-london-medical-laboratory-warns-that-thyroid-issues-escal...
Source: SARS-CoV-2 Research - EXOC2 Oct 31, 2022 2 years ago
SARS-CoV-2 Research: Researchers from Kyoto University - Japan and AMED-CREST, Japan Agency for Medical Research and Development (AMED)- Japan have in a news study found that Exocyst Complex Component 2 (EXOC2) is an important host factor in SARS-CoV-2 infections.
Exocyst complex component 2 is a protein that in humans is encoded by the EXOC2 gene. The protein encoded by this gene is a co...
Source: COVID-19 News - OAS Genes - Heart Failure Oct 31, 2022 2 years ago
COVID-19 News: Researchers from Shanxi Medical University – China have found that the OAS genes plays a key role in COVID-19 induced heart failure.
According to the study team, SARS-CoV-2 infections can damage the heart and lead to heart failure (HF) and even cardiac death. The 2',5'-oligoadenylate synthetase (OAS) gene family encode interferon (IFN)-induced antiviral protei...
Source: Medical News - Alzheimer's Disease Oct 31, 2022 2 years ago
A new study led by researchers from Griffith University, Gold Coast campus, Queensland -Australia has found that activities such as nose picking or plucking nose hairs can lead increase risk for Alzheimer’s disease and dementia!
According to the study team, chlamydia pneumoniae is a respiratory tract pathogen that can also infect the central nervous system (CNS). Recently, the link ...
Source: Medical News - Arthritis Oct 31, 2022 2 years ago
Scientists form the University of Colorado Anschutz Medical Campus – USA have made a startling discovery in which they identified a new strain of gut bacteria from the Subdoligranulum genus that is arthritogenic and able to cause Rheumatoid Arthritis!
The study also involved researchers from Stanford University School of Medicine, California - USA and Benaroya Research Institute, Se...
Source; COVID-19 Drugs -Inhaled Ciclesonide Oct 30, 2022 2 years ago
COVID-19 Drugs: A new study by researchers from the Division of Pulmonary and Critical Care Medicine at MacKay Memorial Hospital- Taiwan has found that the usage of inhaled Ciclesonide reduces risk of mortality and need for mechanical ventilation in hospitalized COVID-19 patients.
Thailand Medical News had already reported as early as August 2020 about the possible prophylactic and also t...
Medical News - Upper-Room Germicidal Ultraviolet-C Irradiation (UR GUV) Devices Oct 29, 2022 2 years ago
A new study by a private American biosafety technology company called R-Zero Systems in Utah has found that using Upper-Room Germicidal Ultraviolet-C Irradiation (UR GUV) devices are effective in eradicating aerosolized SARS-CoV-2 in enclosed areas.
Ultraviolet germicidal irradiation, or UVGI, is the use of ultraviolet (UV) energy to kill viral, bacterial, and fungal organisms. UVGI fixtu...
Source: COVID-19 Research - Epigenetic Changes In Monocytes Oct 29, 2022 2 years ago
COVID-19 Research: Alarmingly. New study findings shows that the SARS-CoV-2 coronavirus is also able to cause epigenetic changes and transcriptomic reprogramming in monocytes of COVID-19 patients!
Such effects by the virus could be associated with the release of aberrant immature monocytes, increased systemic levels of pro-inflammatory cytokines, and changes in immune cell crosstalk in th...
Source: U.S. COVID-19 News Oct 28, 2022 2 years ago
U.S. COVID-19 News: Latest data coming out of only 32 out of 50 states in America shows that there have been 104,258 new daily COVID-19 infections in the last 24 hours and a total of 877 COVID-19 deaths.
https://twitter.com/BNOFeed/status/1585830117510627329
Local physicians and epidemiologists are reporting that the actual numbers could be as high as 2 to 3-fold as there is lack of testi...
Source: SARS-CoV-2 Research - Hub Genes Oct 28, 2022 2 years ago
SARS-CoV-2 Research: Researchers from the Autonomous University of Sinaloa – México and the University of Illinois at Urbana–Champaign – USA have identified five hub genes ie STAT1, IRF7, ISG15, MX1, and OAS1 that increases COVID-19 severity in diabetic kidney disease patients.
DKD or Diabetic kidney disease is a frequently chronic kidney pathology derived from diabetes c...
Source: COVID-19 News - Risk Of Venous Thromboembolism Oct 28, 2022 2 years ago
COVID-19 News: A new study by researchers from Queen Mary University of London – United Kingdom has found that even those who simply contracted mild SARS-CoV-2 infections had a higher risk of developing venous thromboembolism (VTE).
Venous thromboembolism (VTE), a term referring to blood clots in the veins, is an underdiagnosed and serious, yet preventable medical condition that can...
Source: COVID-19 Supplements - GABA Oct 27, 2022 2 years ago
COVID-19 Supplements: A new study led by researchers from University of California, Los Angeles - USA and also involving scientists from Keck School of Medicine of the University of Southern California - USA involving murine models has found that supplementation with the inexpensive amino acid GABA (Gamma-aminobutyric acid) can reduce SARS-CoV-2 viral loads and also help reduce COVID-19 severity a...
Source: Medical News - Fungal Pathogens Oct 27, 2022 2 years ago
The WHO or World Health Organization has issued a public warning about a list of fungal pathogens that are emerging to be a global health threat including many that are developing drug resistance.
For the first time, the WHO drew up a list of identified fungal pathogens that they claim are posing the greatest threat to human health with many already becoming increasingly drug resistant an...
Source: Thailand Medical - Long COVID Erectile Dysfunction Oct 27, 2022 2 years ago
Long COVID Erectile Dysfunction: It seems that for Thais, sex is an important component of their life considering what the country’s night life is famous for and what social media is basically being used for in the country and the volume of pornography that is associated with Thais (just visit the porn sites and add Thai in the search functions for any category or go to sites like Only Fans)...
Source: COVID-19 News - Infections -2023 Oct 26, 2022 2 years ago
COVID-19 News: The Institute for Health Metrics and Evaluation at the University of Washington - USA have predicted based on their existing modeling platform and taking into considerations that current Omicron variants and sub-lineages that has emerged including the BQ.1, BQ.1.1 and XBB variants and their emerging sub-lineages, that daily COVID-19 infections globally could rise to about 18.7 milli...
Source: Medical News - Chronic Heart Failure - COVID-19 Oct 25, 2022 2 years ago
A new study involving murine models by researchers from Hokkaido University Graduate School of Medicine, Sapporo-Japan has found that 5-ALA (of 5-aminolevulinic acid) could reverse or prevent mitochondrial dysfunction that causes chromic heart failure!
5-Aminolevulinic acid is a porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to vi...
Source: Source: COVID-19 News - SARS-CoV-2 Variants & Sub-lineages Oct 25, 2022 2 years ago
COVID-19 News: Despite warnings from Chinese researchers and other virologists that the new SARS-CoV-2 Omicron variants and sub-lineages could be reverting to the same level of pathogenesis as that of the original SARS virus that debuted in 2002, none of these sub-lineages like the BQ.1, BQ.1.1, BA.2.3.20 or even the XBB recombinant variant seems to causing disease severity or even increased death...
Source: Medical News - New Pathogen Oct 25, 2022 2 years ago
Researchers from MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity – United Kingdom have identified a new pathogen that can evade the human host immune system, The new pathogen is hybrid virus comprising of fused viral particles from the RSV (respiratory syncytial virus) and the IAV (influenza A virus) viruses.
To date, it is already known that in...
Source: COVID-19 Research Oct 24, 2022 2 years ago
COVID-19 Research: A new longitudinal cohort study led by researchers from the Universitat de Barcelona - Spain and The Barcelona Institute of Science and Technology - Spain has found that unvaccinated primary healthcare workers sustained seropositivity up to 20.5 months after COVID-19 and long-lasting SARS-CoV-2 humoral immunity!
The COVID-19 Research team that also included researc...
Source: COVID-19 News - Elderly And The Boosters Oct 24, 2022 2 years ago
COVID-19 News: Worryingly, new study findings by researchers from Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID)- UK, University of Cambridge-UK, Wellcome Sanger Institute-UK and University College London have found that booster shots in the aged leads to impaired SARS-CoV-2 neutralization, impaired T cells and also atypical B cells!
These findings warrant f...
Source: Medical News - SARS-CoV-2 - Food Borne Oct 24, 2022 2 years ago
A new study by researchers from the Department of Food and Nutrition, College of Biotechnology and Natural Resources, Chung-Ang University-South Korea has found that the SARS-CoV-2 coronavirus can remain viable on many food products for a long time depending on the storage temperatures.
The study findings showed that at freezing temperatures, SARS-CoV-2 remained viable for up to four week...
COVID-19 News - Newer Omicron Variants -T Cell Escape Oct 23, 2022 2 years ago
COVID-19 News: Already with so many of the newly emerged Omicron variants and sub-lineages displaying greater and wider antibody escape, the potential threat of future variants or sub-lineages characterized by T cell evasion is an ongoing concern that is worrying many researchers.
As SARSCoV-2 approaches optimal cell entry, other selection advantages, e.g., T cell escape, may be utilized ...
Source: Medical News - Flu Shots Oct 22, 2022 2 years ago
Its already clearly showing that the Influenza season has started not only in the Northern hemisphere but also in parts of the Southern hemisphere.
In America, the flu season started earlier than expected.
https://www.cdc.gov/flu/spotlights/2022-2023/early-flu-activity.htm
The flu season this year is being dominated by the H3N2 strain that has been previously associated with more s...
Source: Medical News - Thromboinflammation Driving COVID-19 Thrombosis Oct 22, 2022 2 years ago
A new study by researchers from the University of Bristol – United Kingdom has found that SARS-CoV-2 induced platelet driven thromboinflammation increases the risk of thrombosis in COVID-19 patients.
Numerous past studies have already showed that individuals with COVID-19 are at increased risk of thrombosis, which is associated with altered platelet function and coagulopathy, contri...
The SARS-CoV-2 recombinant variant XBB that is made up of two worrisome variants ie BM.1.1.1 and BJ.1 and is believed to be one of the most immune evasive variants to date besides the BQ.1 and BQ.1.1 variants is now also evolving rapidly and spawning a variety of sub-lineages itself.
The XBB variant that seems to be predominant in circulation in Singapore in the last 2 weeks and also in B...
Source: COVID-19 News -BQ.1, BQ.1.1 - Increased Fusogenicity Oct 21, 2022 2 years ago
COVID-19 News: In a new research by scientists from The Ohio State University – USA and Wexner Medical Center, Ohio - USA to study the neutralization resistance of the subvariants a BQ.1, BQ.1.1, BA.4.6, BF.7 and BA.2.75.2 as well as their ancestral BA.4/5, BA.2.75 and D614G variants against sera from 3-dose vaccinated health care workers, hospitalized BA.1-wave patients, and BA.5-wave patie...
Source: COVID-19 News - Banana Lectin H84T As A SARS-CoV-2 Antiviral Oct 21, 2022 2 years ago
COVID-19 News: A new study conducted by researchers from University of Hong Kong – China, Johannes Kepler University Linz, Linz – Austria and the University of Michigan, Ann Arbor-USA has found that lectins derived from bananas could serve as effective antivirals against the SARS-CoV-2 virus including against the Omicron variant.
As early as 2020, Thailand Medical News has cov...
Source: COVID-19 News - Endothelial Disease Oct 20, 2022 2 years ago
COVID-19 News: In the beginning of the start of the COVID-19 pandemic, we were first led to believe the COVID-19 disease is but a respiratory disease that affects the lungs and later we were given the impression that the hyperinflammatory states or cytokine storms that arose as a result of the SARS-CoV-2 infection was the cause of the various manifestations seen in COVID-19 patients including vari...
Source: Medical News -COVID-19 Isolation Period Oct 19, 2022 2 years ago
A new study by researchers from Stanford University School of Medicine, California-USA has demonstrated that current recommendation by the U.S. CDC for a 5-day isolation period for anyone that test positive for COVID-19 to prevent spread of the disease is inadequate especially when the BA.2 variants and its sub-lineages are concerned!
Surprisingly, one of the non-scientific based decision...
Source: COVID-19 News - Mandatory Genomic Sequencing Oct 19, 2022 2 years ago
COVID-19 News: Never in the history of virology have experts ever witnessed the rapid evolution of a single type of virus spewing out a variety of mutations and spawning an unprecedented rate of new variants and sub-lineages over a very short time period.
In the beginning of the pandemic, many ‘dinosaurs’ in the medical and research communities insisted that the SARS-CoV-2 wil...
Source: SARS-CoV-2 Variants Oct 18, 2022 2 years ago
SARS-CoV-2 Variants: A new study by American researchers from Ohio State University-USA and University of Texas Medical Branch-USA has found that newer Omicron variants or sub-lineages possessing the H655Y mutation tend to display lower fusogenicity with possible implications for lower risk of disease severity initially upon infection.
However, such variants and sub-lineages possessing th...
Source: COVID-19 News - Selective Immunoglobulin A Deficiency (sIgAD) Oct 18, 2022 2 years ago
COVID-19 News: Medical researchers from Auckland Hospital-New Zealand, University of Auckland-New Zealand and Wellington Hospital-New Zealand have in a new study found that selective immunoglobulin A deficiency (sIgAD) is a risk factor for severe COVID-19.
Selective IgA deficiency (sIgAD) is an immune system condition in which one lacks or don't have enough immunoglobulin A (IgA), a p...
Source: Medical News - COVID-19 - Blood And Skin Cancers Oct 18, 2022 2 years ago
In an alarming new development, medical researchers from Ribeirão Preto Faculty of Medicine, Universidade de São Paulo-Brazil have found that SARS-CoV-2 induced immunological dysregulation can potentially increase the risk of relapses of IB cutaneous T-cell lymphomas such as Sézary Syndrome and Mycosis Fungoides.
The study team presented a documented clinical case stu...
Source: COVID-19 News - Mesenteric Panniculitis And Acute Abdominal Pain Oct 17, 2022 2 years ago
COVID-19 News: Despite warnings that the newer Omicron variants and sub-lineages that have emerged and started circulating since weeks 18 to now are displaying more tropism towards the gastrointestinal tissues and causing a variety of gastrointestinal tissues, many scientists not in clinical practice or in the study of the pathogenesis of these new variants are expressing skepticisms.
Tha...
Source: Medical News - Pediatric COVID-19 - Febrile-Seizures Oct 17, 2022 2 years ago
South Korean medical researchers from Jeonbuk National University Medical School, Wonkwang University Medical Center, Gunsan Medical Center, the Presbyterian Medical Center and Design Medical Center in a new study have found that with the emergence of the Omicron variant and its various sub-lineages, the incidence of febrile-seizures has increased among children tested positive for COVID-19. Alarm...
Source: Medical News - SARS-CoV-2 Infections Oct 16, 2022 2 years ago
A new American study involving researchers from Washington University in St. Louis, University of California, University of Washington, and the Medical College of Georgia at Augusta University has found that far more people have been infected with the SARS-CoV-2 virus, with possible amounts even reaching 2.4 billion people compared what was reported officially!
The study team using a new ...
Long COVID News: A new study conducted by researchers from Stellenbosch University-South Africa has found that the increased levels of six different inflammatory molecules in most post-COVID individuals known to be key drivers of endothelial and clotting pathology, causes thrombotic endotheliitis, a contributing factor to Long COVID.
These six inflammatory molecules were:
-1) Von Willebra...