Thailand Medical News

China Causing Global Herceptin Shortage

Staff Writer, TMN Jul 03, 2018 6 years ago

When Roche got Herceptin onto China’s national insurance program, it didn’t expect demand to surge so quickly, overwhelming its production capacity there. Now, to cope with a nationwide shortage, it’s shifting to a different manufacturing site to amp up supplies of the cancer therapy. Roche applied to change Herceptin's existing production site for China to a high...

Keytruda, Tecentriq Labeling Updated to Limit Use in Urothelial Cancer

Staff Writer, TMN Jul 04, 2018 6 years ago

The US Food and Drug Administration (FDA) has approved updated labeling for Keytruda (pembrolizumab; Merck) and Tecentriq (atezolizumab; Genentech) for patients with locally advanced or metastatic urothelial cancer who are not eligible for cisplatin-containing chemotherapy. The USFDA is continuing to review Merck's Keytruda and Roche's Tecentriq in pr...

Study indicates potential breakthrough HIV drug

Staff Writer, TMN Jul 05, 2018 6 years ago

French biotech Abivax’s might be on the verge of HIV cure and prevention discovery, after achieving a significant reduction of viral load patients during the first 28 days of treatment. The company has announced results from the first group of patients in its most recent phase 2a trial testing the potential HIV cure treatment codenamed ABX464. The study aimed at acc...

Case Report Details Use of Buprenorphine for Treatment of Kratom Dependence

Staff Writer, TMN Jul 06, 2018 6 years ago

Kratom shares structural similarities with opioid analgesics Opioid-like dependence due to chronic kratom use can be successfully treated with buprenorphine, according to a recent case report published in the Journal of Addiction Medicine. Kratom, an herbal supplement that shares structural similarities with opioid analgesics, has recently grown in popularity in the West ...

Statins increase the risk of developing diabetes in at-risk people

Staff Writer, TMN Jul 07, 2018 6 years ago

Among susceptible individuals, statins — which are a common cholesterol-lowering medication — could increase the risk of type 2 diabetes by 30 percent. These new findings are sure to reignite debate. The relationship between statins and diabetes is investigated in a new study. Statins lower cholesterol by reducing its production in the liver. They do this...

US FDA Approves Zemdri

Staff Writer, TMN Jul 08, 2018 6 years ago

Zemdri (plazomicin) Approved by FDA for the Treatment of Adults with Complicated Urinary Tract Infections (cUTI) Achaogen, Inc., a biopharmaceutical company developing and commercializing innovative antibacterial agents to address multidrug resistant (MDR) gram-negative infections, announced that the U.S. Food and Drug Administration (FDA) has approved Zemdri (plazomicin) for adults with complic...

UniQure’s starts pivotal haemophilia B gene therapy trial

Source: uniqure.com Jul 09, 2018 6 years ago

The treatment could relieve haemophilia B patients from factor IX replacement drugs UniQure has enrolled the first patient in its registration trial of haemophilia B gene therapy candidate AMT-061 as it tries to keep ahead of a rival project from Spark Therapeutics/Pfizer. The subject is the first out of around 50 subjects that will be recruited into the open-label HOPE-B trial of AMT-061, an a...

Suffering IBS symptoms? THIS new pill has been scientifically proven to help

Staff Writer, TMN Jul 07, 2018 6 years ago

IRRITABLE BOWEL SYNDROME is a common condition which can cause bouts of stomach cramps, bloating, diarrhoea and constipation - but a probiotic pill has been scientifically proven to relieve symptoms. IBS is thought to affect up to one in five people at some point in their life, and while there are a host of over-the-counter and home remedies available, a new probiotic supplement has been proven i...

Fat : The future of regenerative therapy

Staff Writer, TMN Jul 09, 2018 6 years ago

Regenerative therapy is a cell-based technique using stem cells to boost tissue regeneration. Though many different stem cells are used, one of the most promising is fat-derived adipose stem cells. When tissue is damaged your body will regenerate it by replacing damaged cells through cell growth and division. Your DNA determines how your body knows when and where to regenerate. Similar to...

Metformin – new possibility to reverse lung fibrosis

Source: Journal Nature Medicine Jul 09, 2018 6 years ago

Metformin found to help reverse lung fibrosis in mice The type 2 diabetes drug metformin could be used to help treat lung fibrosis condition in the future, researchers have said. Idiopathic pulmonary fibrosis (IPF) or lung fibrosis is a respiratory disease which occurs when scars are formed in the lung tissues, leading to breathing problems. It can develop after lung injuri...

New gene therapy drug for rheumatoid arthritis undergoes phase 1 trial

Staff Writer, TMN Jul 09, 2018 6 years ago

Arthrogen, a biopharmaceutical company specializing in gene therapy, is now recruiting individuals with rheumatoid arthritis to test the new drug ART-I02. Khun Nantida does not wear clothes with buttons. Most of her pants have waistbands and do not require zipping. She uses only electric toothbrushes because she cannot brush her teeth as efficiently on her own. When Khun Nantida cooks for...

How to store your allergy meds

Staff Writer, TMN Jul 04, 2018 6 years ago

There are many different allergy medications which, like other drugs, need to be stored under the right conditions to remain effective. In order for medications to remain effective until their expiry date, they need to be stored correctly , regardless of the diseases or conditions they're intended to treat or prevent. This is important in the case of allergy medication as a severe aller...

Early source of irritable bowel syndrome discovered

Staff Writer, TMN Jul 05, 2018 6 years ago

Michigan State University scientists have identified an early cause of intestinal inflammation, one of the first stages of inflammatory bowel disease and irritable bowel syndrome, which afflict around 11 percent of the world's population. NK2R (green) and enteric glial (blue) The discovery, featured in the current issue of Cellular and Molecular Gastroenterology and Hepatology, points...

A virus that may actually boost not weaken our immune system

Source: University of Arizona Jul 06, 2018 6 years ago

Janko Nikolich-Zugich, M.D., Ph.D. Credit: UA College of Medicine – Tucson Our immune system is at its peak when we're young, but after a certain age, it declines and it becomes more difficult for our bodies to fight off new infections. "That's why older people are more susceptible to infections than younger people," explains Janko Nikolich-Zugich, MD, Ph.D., co-director...

These antibiotics may endanger vascular health

Staff Writer, TMN Jul 07, 2018 6 years ago

A type of antibiotic used in treating bacterial infections has been tied to many adverse health events, leading specialists to advise caution in the prescription of these drugs. Recent evidence now confirms that they increase the risk of aortic disease, which is a condition that damages the main artery of the human body. Various Types of Fluoroquinolones Fluoroquinolones, a type of antibiotic,...

A New Simple Blood Test For All Types Of Cancers

Staff Writer, TMN Jul 08, 2018 6 years ago

Scientists are designing a blood test that could detect cancer before symptoms occur. Early detection allows early treatment and prevents cancer progression. Cancer is usually diagnosed after a patient has been experiencing symptoms. At this point, the tumor has already grown significantly and often has spread to other organs. Later stage cancers are more difficult to treat, have lower sur...

KRATOM Debate in the US

Davic C Holzman, Mcmahon Grp Jul 09, 2018 6 years ago

The US FDA has continued to voice serious concerns about an opioid like plant, Kratom (Mitragyna speciosa)., a close relative of the coffee tree that is embraced by many pain patients as a treatment alternative to pain drugs such as opioids. A dangerous side effect profile pointed out by the agency and strong opinions on its efficacy on the part of its users—who often ingest the leaves in po...

Is the Anti-Aging Pill finally here?

Staff Writer, TMN Jul 03, 2018 6 years ago

A drug derived from an Easter Island bacterium extends the life of lab animals. People could be next. Can a pill make you younger? One of the few drug studies ever carried out in an attempt to address this question was reported by Novartis on Christmas Eve 2017. The company had sought to see whether giving low doses of a drug called everolimus to people over 65 increased their response to flu va...

Molecular Switch Links High-Fat Diet to Prostate Cancer Metastasis

Source: cancer.org Jul 01, 2018 6 years ago

A new study in mice has revealed a molecular link between a high-fat diet and the growth and spread of prostate cancer. The findings raise the possibility that changes in diet could potentially improve treatment outcomes in some men, the study leaders believe. In the study, the researchers also showed that an anti-obesity drug that targets a protein that controls fat synthesis could po...

AI Beats Doctors at Cancer Diagnoses

Staff Writer, TMN Jul 02, 2018 6 years ago

The machine was able to more accurately diagnose malignant melanoma and benign nevi. The dermatologists accurately detected an average of 86.6 percent of melanomas, compared to the CNN's 95 percent accuracy. MACHINE MAY BE BETTER than man when it comes to detecting skin cancer in patients. For the first time, researchers have shown that artificial intelligence known as deep learning c...

Gene Therapies for Cancer, Only for the Rich?

Staff Writer, TMN Jul 03, 2018 6 years ago

Cascade of Costs Could Push New Gene Therapy Above US$1 Million Per Patient Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the US$475,000 price tag for the country’s first gene therapy, Novartis’ Kymriah, a leukemia treatment approved in August 2017. But the total costs of Kymriah and the 21 similar drugs in deve...

Status of Cancer Cures

Staff Writer, TMN Jul 04, 2018 6 years ago

Cancer is the leading cause of death across the globe. For years now, researchers have led meticulous studies focused on how to stop this deadly disease in its tracks. How close are we to finding more effective treatments? The World Health Organization (WHO) note that, worldwide, nearly 1 in 6 deaths are down to cancer. In the United States alone, the National Cancer Institut...

Putting the brakes on metastatic cancer

Staff Writer, TMN Jul 05, 2018 6 years ago

Medical researchers find 11 genes responsible for the spread of cancer A groundbreaking discovery has identified previously unknown therapeutic targets that could be key to preventing the spread of cancer. Researchers found that by inhibiting several newly identified gene targets they could block more than 99.5 per cent of cancer metastasis in living cells. In a new study publishe...

SMAD4 clue to colon cancer

Staff Writer, TMN Jul 06, 2018 6 years ago

Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Reporting last month in the journal Cellular and Molecular Gastroenterology and Hepatology, Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4. &nbs...

Researchers develop tool to more easily detect esophageal cancer cells

Staff Writer, TMN Jul 07, 2018 6 years ago

Dr. Zui Pan. Credit: University of Texas at Arlington Researchers at the University of Texas at Arlington's College of Nursing and Health Innovation have developed a new nanoparticle-based platform for simultaneous imaging and treatment of esophageal cancer. Together with colleagues from The Ohio State University, researchers manufactured polypeptide nanoparticles, which have ne...

Altering Chemotherapy Improves Outcomes in Early-Stage Pancreatic Cancer

Staff Writer, TMN Jul 08, 2018 6 years ago

Results from two clinical trials are expected to improve the outlook for people diagnosed with early-stage pancreatic cancer that can be treated with surgery. In the first trial, changing the type of chemotherapy given after surgery from a single drug to a multi-drug regimen greatly improved how long patients lived. Patients in the trial treated with the multi-drug regimen survived for an ...

Fungal toenail drug able to eliminate sleeping colorectal cancer cells immune to chemotherapy, finds study

Staff Writer, TMN Jul 09, 2018 6 years ago

Treatment wakes up dormant tumour cells which can allow cancer to come back after chemotherapy before slamming on an irreversible ‘stop’ button A medication more commonly used to treat fungal toenail infections may be helpful in fighting off persistent colorectal cancers which kill 4,000 people in the Thailand each year, a new study has found. Colore...

Cervical cancer prevention in Thailand - a model of success

Source: Doi.org Jul 10, 2018 6 years ago

The Provincial Health Office of Roi Et, Thailand, received the 2018 UN Public Service Award for its cervical cancer prevention programme and promoting gender responsive public services. Just two decades ago, cervical cancer was the most common cancer for women in Thailand and the country struggled to provide the standard cytology and referral approach due to lack of infrastructure, acce...

Reversing Brain Aging Using Magnesium L-Threonate

Staff Writer, TMN Jul 10, 2018 6 years ago

MIT researchers discovered and patented magnesium L-threonate based on its unique ability to boost brain levels of magnesium. Rapid absorption and ability to enter the brain enables this magnesium to structurally reverse certain aspects of brain aging.1-4 A recent human study demonstrates the benefits of magnesium L...

Novel Senolytic Osteoarthritis drug investigated

Staff Writer, TMN Jul 09, 2018 6 years ago

Currently, there is no cure for osteoarthritis, the most common joint problem in the United States. A new study brings hope of a single-injection fix. The drug on trial clears out old cells from the joints. Osteoarthritis (OA) is a type of arthritis that occurs when cartilage at the ends of bones wears down. It can affect any joint in the body, but it most commonly affects the hands, ne...

Sleep Disorder Linked to Brain Changes Seen in Dementia

Staff Writer, TMN Jul 08, 2018 6 years ago

Obstructive sleep apnoea has been linked to brain changes seen in the early stages of dementia, University of Sydney research reveals. Published today in The European Respiratory Journal, the study's authors say the finding provides evidence that screening older people for obstructive sleep apnoea (OSA) and providing treatment where needed could help prevent dementia in this po...

Beware! Consuming bacteria-infected milk can trigger rheumatoid arthritis

Staff Writer, TMN Jul 07, 2018 6 years ago

A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a study. Researchers at the University of Central Florida (UCF) in the US have discovered a link between rheumatoid arthritis and Mycobacterium avium subspecies paratuberculosis, known as MAP, a bacteria found in about half the cows i...

Biogen Alzheimer's drug success: A big step because almost every dementia trial before it has ended in failure

Source: CNBC Jul 06, 2018 6 years ago

Biogen announced surprise successful results from an Alzheimer's drug clinical trial that sent shares of the pharmaceutical company soaring. Alzheimer's drug research has been plagued by years of unrelenting failures, leading companies including Pfizer to give up the search for new compounds. Dementia experts have questioned the narrow focus from biotech companies on amyloid ...

3 Promising Anti-Aging Therapies Research

Staff Writer, TMN Jul 03, 2018 6 years ago

Some researchers believe they will soon be able to slow or even stop the body's clock—at least for a little while The majority of older people live out their final years with at least one or two chronic ailments, such as arthritis, diabetes, heart disease or stroke. The longer their body clock ticks, the more disabling conditions they face. Doctors and drug companies traditionally...

Long-sought structure of telomerase paves way for new drugs for aging, cancer

Staff Writer, TMN Jul 04, 2018 6 years ago

Cryo-electron microscopy images reveal details of protein, RNA binding and possible drug-target sites Shown is the space-filling model of human telomerase holoenzyme structure determined by cryo-electron microscopy (cryo-EM). Telomerase catalyzes the synthesis of telomeric DNA (green) at the ends of chromosomes (blue) to compensate for the loss of telomeres during genome replication. The structu...

Anti-aging field 'explodes' in pursuit of healthy old age

Staff Writer, TMN Jul 02, 2018 6 years ago

Experts on the forefront of anti-aging medicine say the field is booming, with therapies on the horizon to target illnesses like cancer and Alzheimer's and make for a healthier, older population in the years to come. Such remedies are increasingly important because of the world's aging population. Growing old, experts say, is a leading risk factor for most human diseases and a majo...

People are getting hand injections to reverse signs of aging

Staff Writer, TMN Jul 01, 2018 6 years ago

Men and women are now opting for hand injections in an effort to turn back time and reverse telltale signs of ageing. For many, hands can be a sign of someone's age - as they are often the first body part to show protruding veins and tendons, lack of skin elasticity, and sunspots. Now, in response to a growing number of people who'll do whatever they can to stay looking ...

Thailand’s Siriraj Hospital develops a rapid and accurate method to identify Rare or Uncommon Pathogenic Bacteria

Staff Writer, TMN Jul 10, 2018 6 years ago

The MALDI TOS Spectrometer In a recent article published in the Siriraj Medical Journal, a team at the Department of Microbiology. Siriraj Hospital, had developed a new method of identifying rare pathogenic bacteria using the Maldi Tos Mass Spectrometry Method. (MALDI is the abbreviation for Matrix Assisted Laser Desorption/Ionisation, while TOS is the abbreviation for Time of flight mass...

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COVID-19 News: Will SARS-CoV-2 Infections Ultimately Lead To An Increased Incidence Of Head And Neck Cancers?

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