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Featuring latest Drug Developments and Treatment Protocols and also Updates about the Pharmaceutical Industry , both in Thailand and abroad, latest USFDA and Thai FDA approvals and also Corporate News with regards to various Pharma companies.
Medical News: Sorafenib, a groundbreaking multi-targeted anti-cancer drug, has been widely used for treating hepatocellular carcinoma, advanced renal cell carcinoma, and differentiated thyroid carcinoma. These cancers represent significant global health burdens. Hepatocellular carcinoma alone is the sixth most common cancer worldwide and the third leading cause of cancer-related deaths. Sorafenib ...
Medical News: A potential human case of bird flu, also known as H5N1, has been reported in Louisiana, marking the first known instance in the state. The Louisiana Department of Health announced that the affected individual, a resident of southwestern Louisiana, is currently hospitalized after exposure to sick and dead birds suspected of carrying the virus. This alarming development highlights ongo...
Medical News: A New Era in Epilepsy Treatment
Epilepsy, a neurological condition that affects millions globally, often leaves patients grappling with seizures despite medication. Researchers from Lipinski University in Poland and the Medical University of Lublin have brought forth promising findings on cenobamate, a newly approved antiseizure medication.
Polish Researchers Find That Cenobama...
Medical News: FDA Takes Action Over Impurities in Chronic Kidney Disease Drug
The U.S. Food and Drug Administration (FDA) has announced a recall of a medication widely used to manage chronic kidney disease (CKD) and related conditions. The drug, Cinacalcet, is produced in India by Dr Reddy’s Laboratories and distributed by Dr. Reddy’s Laboratories American subsidiary, based in New Jers...
Medical News: U.S. FDA Adds New Safety Label for Weight Loss Medications
The U.S. Food and Drug Administration (FDA) has recently updated the safety labels on popular weight loss medications like Ozempic and Wegovy, highlighting a new warning for patients using these drugs. The warning addresses the risk of a condition known as pulmonary aspiration, which can occur during procedures involving gen...
Med News: Researchers from the Department of Dermatology and Allergy at Copenhagen University Hospital in Denmark have unveiled insights about the infection risks associated with Janus Kinase (JAK) inhibitors, particularly for dermatology patients. Their findings, published in a recent study, underscore a heightened risk of herpes zoster (also known as shingles) and other infections in patients un...
Medical News: In recent research from Saudi Arabia and Jordan, scientists have taken a closer look at the effects of etoricoxib, a widely used anti-inflammatory drug. With a growing demand for medications that relieve pain without severe side effects, etoricoxib has been a go-to choice for people dealing with chronic pain. However, researchers are now examining its safety for heart and kidney heal...
Medical Research News: How Skin Pigmentation Affects Medication
A groundbreaking new study is shedding light on how skin pigmentation may play a surprising role in how well certain medications work. According to researchers from the University of California, Riverside, and others, melanin, the pigment that gives skin its color, could act as a "sponge" for some drugs, influencing how qui...
Med News: The Growing Use of PPIs and Emerging Concerns
Proton pump inhibitors (PPIs) have been a go-to treatment for reducing stomach acid since the 1980s. Commonly used to manage conditions such as gastroesophageal reflux disease (GERD), ulcers, and functional dyspepsia, these medications are widely prescribed. In fact, a quarter of the adult population is on PPIs, but up to 70% of prescription...
Med News: A recent case report has shed light on a lesser-known complication associated with the use of gabapentin, a common medication prescribed for nerve pain and seizures. This Med News report discusses how gabapentin can potentially lead to adrenal insufficiency and increase the risk of infection, especially in patients undergoing surgery. Researchers from the 1st Department of Orthopaedics a...
Med News: Amlodipine and Gingival Enlargement
Recent research from the University of Kragujevac, Serbia, sheds light on a lesser-known side effect of amlodipine, a widely used medication for hypertension - gingival enlargement. This Med News report delves into the findings of a comprehensive study aimed at understanding how amlodipine affects gingival tissues and the broader implications for pati...
Med News: In a groundbreaking development for allergy sufferers, the U.S. Food and Drug Administration (FDA) has approved the first-ever epinephrine nasal spray, known as Neffy, for treating severe allergic reactions, including life-threatening anaphylaxis.
https://www.fda.gov/news-events/press-announcements/fda-approves-first-nasal-spray-treatment-anaphylaxis
U.S. FDA approves Neffy, ...
Pharma News: In a significant development affecting the Indian pharmaceutical market, French multinational pharma giant Sanofi has announced the voluntary recall of two popular children's medications - Allegra Suspension (Fexofenadine Hydrochloride Suspension) and Combiflam Suspension (Ibuprofen and Paracetamol Suspension). The recall has been initiated as a precautionary measure due to concer...
Med News: Fibrotic interstitial lung diseases (FILDs) represent a group of conditions characterized by scarring of the lung tissue, leading to serious breathing difficulties and decreased quality of life. These diseases encompass a wide range of conditions, including idiopathic pulmonary fibrosis (IPF), connective tissue disease-associated interstitial lung disease (CTD-ILD), and lung diseases cau...
TCM News: Researchers Highlight Sheng Mai San's Anti-inflammatory Potential
In a recent groundbreaking study, researchers from The Hong Kong Polytechnic University and Hangzhou Normal University have demonstrated the potential of Sheng Mai San (SMS), a traditional Chinese medicine formula, in treating inflammatory bowel disease (IBD). This TCM News report delves into the significant findings ...
Medical News: A groundbreaking study has unveiled a startling discovery: catecholamines and catecholaminergic drugs can interfere with human testicular functions. This Medical News report delves into the significant findings and their potential implications on male fertility, a concern that resonates with many.
Study shockingly reveals that Catecholamines and Catecholaminergic drugs can inter...
Med News: Glioblastoma, a highly aggressive brain tumor, remains one of the most challenging cancers to treat. Traditional therapies often fail due to the tumor's ability to invade surrounding brain tissue. However, a recent study suggests a new approach that could change the landscape of glioblastoma treatment. Researchers from the IIAIGC Study Center in Burlington, VT, USA, propose repurposi...
Med News: Understanding Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS) is a chronic pain condition that affects millions of people worldwide. Characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and various other symptoms, FMS is a complex condition that significantly impacts the quality of life of those affected. This Med News report delves into the latest pharmacolo...
Med News: Human Metapneumovirus (HMPV) is a major cause of respiratory infections, especially in young children, the elderly, and those with weakened immune systems. Despite its significant impact, there is currently no specific antiviral treatment or vaccine available for HMPV. This has left doctors with limited options, primarily focusing on supportive care to manage symptoms. However, a recent ...
Med News: Antidepressants are crucial in managing depression, a common mental health issue affecting millions worldwide. However, these medications often come with side effects, one of the most significant being sexual dysfunction. This side effect can greatly impact the quality of life and lead to discontinuation of medication. A recent study by researchers from the University of Ulm-Germany and ...
Med News: Meldonium, a synthetic drug developed in the 1970s by Latvian scientists, has a fascinating history marked by its transition from agricultural uses to potential medical marvel. Initially designed to boost livestock growth, meldonium quickly found favor in human medicine due to its heart-protective properties. However, its journey from a heart medication to a controversial sports enhancer...
Med News: Understanding Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver condition that affects millions worldwide. This disease begins with the accumulation of fat in the liver and is often linked to metabolic syndrome, which includes obesity, diabetes, high blood pressure, and high cholesterol. Recently, the term NAFLD has been replaced with Me...
Med News: Intrauterine Adhesions
Intrauterine adhesion (IUA) is a medical condition that affects women's reproductive health. It often manifests as irregular menstruation, pelvic pain, infertility, and recurrent miscarriages. Studies show that around 31.6% of women of childbearing age may suffer from IUAs. Traditionally, hysteroscopy is used to diagnose and treat IUAs, but it has limitations ...
Bowel Cancer News: A Gamechanger in Bowel Cancer Treatment
In a groundbreaking announcement at the annual meeting of the American Society of Clinical Oncology (ASCO) 2024, researchers have highlighted the exceptional results of a clinical trial involving pembrolizumab, an immunotherapy drug.
https://conferences.asco.org/am/abstract-policies-embargoes-exceptions
Researchers at ASCO 202...
Medical News: A recent study conducted by researchers from the University of Hong Kong, has unveiled promising results on the use of statins for cardiovascular disease (CVD) prevention and overall mortality reduction in seniors, including those aged 85 and above. This groundbreaking research covered in this Medical News report sheds light on the significant benefits of statin therapy in an often-u...
The Discovery: A New Hope for Sepsis Treatment
In a groundbreaking study, scientists from The Second Affiliated Hospital at Zhejiang University School of Medicine in Hangzhou, China, have uncovered the pivotal role that adaptor proteins play in regulating the innate immune response during sepsis. Sepsis, a life-threatening condition caused by an overwhelming immune response to infection, remains ...
Med News: Sepsis, a life-threatening response to infection, requires prompt and effective treatment to prevent organ failure and death. Broad-spectrum antibiotics are often the first line of defense against sepsis, aimed at targeting a wide range of potential pathogens. However, recent studies suggest that not all broad-spectrum antibiotics are equally effective and some might even be detrimental....
Med News: In a groundbreaking development, researchers at HMRI (Hunter Medical Research Institute) and the University of Newcastle have conducted a randomized clinical trial that showcases the potential of azithromycin, a macrolide antibiotic, to induce remission in moderate to severe asthma cases. The study, led by Professor Peter Gibson from the HMRI Asthma and Breathing program and Dr Dennis Th...
Med News: Understanding the Blood-Brain Barrier
The blood-brain barrier (BBB) is a critical defense mechanism that safeguards the brain from harmful substances while allowing essential nutrients to pass through. This barrier, composed of specialized cells, presents a formidable challenge for drug delivery in treating neurological disorders. However, recent groundbreaking research led by Dr Rosema...
Med News: The practice of administering sedatives to individuals detained by police has quietly spread across the United States over the past decade and a half. This approach, aimed at reducing violence and ensuring rapid medical treatment, has come under scrutiny due to questionable scientific foundations and tragic outcomes. An investigation by the Associated Press, in collaboration with Frontli...
Med News: In recent years, the commonly prescribed anxiety drug pregabalin has come under scrutiny due to a significant increase in linked fatalities. This surge in deaths, which more than doubled from 187 in 2018 to 441 in 2022 in England and Wales, has sparked concerns about the safety of this medication.
Death registrations related to Gabapentin or Pregabalin, England and Wales: 2018 and 2022 ...
Pharma News: In a disconcerting turn of events, the pharmaceutical industry in Himachal Pradesh, India, is facing intense scrutiny as 374 medicine samples from companies located in the Baddi-Barotiwala and Nalagarh areas have failed quality tests in the past year. The revelation came to light during the Question Hour session in the Assembly House, raising concerns among various Members of the Legi...
Cancer News: In a recent study led by the University of Bristol, new research sheds light on the potential of glitazones, a type of anti-diabetic drug, in lowering the risk of primary and secondary brain cancers. The study covered in this Cancer News report, suggests that the long-term use of glitazones among diabetic patients may offer a protective effect against brain tumors. This revelation ope...
Pancreatic Cancer News: Metastatic pancreatic adenocarcinoma, a particularly challenging form of cancer, has received a significant breakthrough with the recent approval of NALIRIFOX by the U.S. Food and Drug Administration (FDA). NALIRIFOX is a groundbreaking four-drug chemotherapy regimen consisting of irinotecan liposome (Onivyde), oxaliplatin, leucovorin, and fluorouracil. The approval follows...
Drug Recall Alert: In a recent development, UK-based healthcare company Haleon has issued a voluntary nationwide recall in the United States for certain batches of Robitussin cough syrups. The recall comes in response to the detection of microbial contamination in eight batches of Robitussin Honey CF Max Day Adult and Robitussin Honey CF Max Nighttime Adult. The affected products have expiration d...
Drug News: The U.S. Food and Drug Administration (FDA) has recently issued a boxed warning on Chimeric Antigen Receptor T-cell (CAR-T) therapies, citing concerns that these innovative cancer treatments may pose a risk of causing secondary cancers. While the FDA emphasizes that the overall benefits of CAR-T therapies continue to outweigh potential risks, the move comes in response to 25 reports of ...
Pharma News: India is a country where doctors and researchers can be easily bought for small sums of monies to manipulate studies and officials at regulatory agencies in India can be easily bribed to issue relevant drug and supplement approvals or licenses despite ‘half-baked’ supporting data. Worse, the various companies in India that are known to manufacture various generic drugs, su...
FDA Drug Recall: In a significant development in the pharmaceutical industry, KVK-Tech, Inc. has announced a voluntary nationwide recall of one lot of Betaxolol Tablets, USP 10 mg (Batch Number: 17853A).
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/kvk-tech-inc-issues-voluntary-nationwide-recall-one-lot-betaxolol-tablets-usp-10-mg-batch-number
This decision com...
The Coronaviridae family comprises a diverse group of enveloped, positive-sense single-stranded RNA viruses responsible for a range of diseases in animals and humans. The family's rapid evolution is driven by high genomic nucleotide substitution rates and recombination events. Among these viruses, seven human coronaviruses (HCoVs) have been identified, including the seasonal HCoVs (sHCoVs) HCo...
Thailand Medical News Team Aug 21, 2023 1 year ago
Med News: In a groundbreaking development, the U.S. Food and Drug Administration (FDA) has granted approval for Akeega, a novel treatment that marries the power of poly(adenosine diphosphate-ribose) polymerase (PARP) inhibition with abiraterone acetate, to combat BRCA-positive metastatic castration-resistant prostate cancer (mCRPC). This innovative therapy offers hope to a subset of patients who h...
Med News: As winter grips Australia and cold and flu cases continue to surge, parents across the nation are facing a new challenge - a shortage of essential medicines for their children. This alarming scarcity is attributed to a combination of global supply disruptions and heightened demand due to the ongoing COVID-19 pandemic, creating a perfect storm that has left many families struggling to fin...
Thailand Medical News Team Aug 09, 2023 1 year ago
Pharma News: In a groundbreaking development, Novo Nordisk's revolutionary weight loss drug, Wegovy, has not only captured the attention of the weight-conscious population but has now demonstrated a remarkable potential to significantly lower the risk of major cardiovascular events (MACE).
The results of an extensive clinical trial have unveiled a 20% reduction in the occurrence o...
Thailand Medical News Team Aug 09, 2023 1 year ago
Pharma News: You've probably seen the unsettling commercial that warns that the virus responsible for shingles might already be lurking within you if you had chickenpox as a child. This chilling message serves as a reminder for people to consider getting the shingles vaccine. But, alas, the vaccine doesn't provide foolproof protection against shingles; it simply helps mitigate the symptoms...
Thailand Medical: In recent years, low-dose aspirin has been widely prescribed to reduce the risk of cardiovascular events, including strokes, in both primary and secondary prevention settings. The evidence supporting its use, particularly in younger populations, has been encouraging, leading to its widespread adoption.
However, the risks and benefits of aspirin therapy become more nuance...
Medical News - Drug News - Metformin - Muscle Atrophy Jul 26, 2023 1 year ago
Study found that metformin helps muscle cells better remodel and repair tissue during periods of recovery after inactivity.
Drug News: When you hear about diabetes medications, muscle function might not be the first thing that comes to mind. However, groundbreaking research from the University of Utah Health has revealed that the common diabetes drug, Metformin, has unexpected applic...
COVID-19-News - Cytochrome P450 3A4-Mediated Drug Metabolism And Drug Interactions Jun 24, 2023 2 years ago
Drugs Such As Midzolam, Lopinavir, Etc Used On COVID-19 Patients Could End Up Killing Them Instead!
COVID-19 News: In a groundbreaking discovery, Canadian scientists from the College of Pharmacy at Dalhousie University have issued a warning about the potential deadly consequences of COVID-19 on cytochrome P450 3A4 (CYP3A4)-mediated drug metabolism and drug interactions. This revelation has ...
Medical News - Ivermectin - Gut Dysbiosis - Liver Damage May 04, 2023 2 years ago
Medical News: A new study by researchers from Department of Microbiology and Immunology at the Federal University of Alfenas – Brazil has worryingly found that usage of the antiparasitic drug, Ivermectin can lead to gut dysbiosis and liver damage but not does not increase susceptibility to Pseudomonas aeruginosa lung infection.
The study findings revealed the devastating effects of ...
Pharma News - diclofenac - UGT2B17 May 01, 2023 2 years ago
Pharma News: New research has unveiled the potential reason behind the alarming side effects of a widely-used painkiller, diclofenac, putting millions of people at risk for severe complications. A misunderstood enzyme responsible for metabolizing the drug may be the key factor leading to serious health consequences, including heart damage.
In a groundbreaking study, scientists have discovered a s...
Medical News - Ifosfamide Apr 24, 2023 2 years ago
Medical News: In a startling revelation, researchers from Washington State University (WSU) have discovered that a common chemotherapy drug, ifosfamide, could carry a toxic inheritance for the children and grandchildren of adolescent cancer survivors. This study is among the first to demonstrate that disease susceptibility can be passed down to unexposed third-generation offspring from certain dru...
Drug News - Medications - Kidneys Apr 04, 2023 2 years ago
Everyday medications found in your cabinet could be silently damaging your kidneys. Surprisingly, 20% of kidney damage results from both prescription and over-the-counter (OTC) medications. This alarming statistic raises concerns, especially considering 1 in 3 people in the U.S. are at risk for kidney disease.
https://www.aafp.org/pubs/afp/issues/2008/0915/p743.html#afp20080915p743-b1
https...
COVID-19 News - SARS-CoV-2 Altered Blood-Brain Barrier - Drug Transport Apr 01, 2023 2 years ago
COVID-19 News: A new study by Mexican medical scientists has found that SARS-CoV-2 virus is able to alter the Blood-Brain Barrier of the human host with concerning implications as many of the drugs used during treatment can also thereafter gain access to the brain when in the first place, during development and research, they were made knowing very well that their active molecules would never be a...
Fumarate Hydratase -COVID-19, Sepsis, Lupus, Arthritis Mar 30, 2023 2 years ago
Fumarate Hydratase: In an effort to understand the progression of inflammatory diseases, researchers at the Trinity Biomedical Sciences Institute's School of Biochemistry and Immunology in Trinity College Dublin have made a significant breakthrough. This new understanding reveals a potential therapeutic target for a variety of inflammatory conditions.
The team found that an enzyme cal...
Med News - Metformin - Osteoarthritis Mar 27, 2023 2 years ago
Med News: A new study led by researchers from Stanford University, California-USA that also included scientists from Chinook Therapeutics, Washington-USA and The VA Palo Alto Health Care System, California-USA has found that metformin use is associated with lower incidence of osteoarthritis.
Osteoarthritis (OA), the most commonly observed type of arthritis, is associated with considerable...
Pharma News -Nitroglycerin Spray Shortage Mar 22, 2023 2 years ago
Pharma News: Shortage Of Nitroglycerin Spray, A Heart Medication In Canada Is Expected to Extend To The America and Europe Due To Raw Materials Crisis.
Pharma News: A shortage of a critical heart medication, nitroglycerin spray, has sparked concerns among patients and healthcare providers in Canada, particularly in Alberta.
The fast-acting nitroglycerin spray is used by spraying on...
U.S. Medical News - Pfizer Recalls Nurtec ODT Migraine Tablets Mar 19, 2023 2 years ago
U.S. Medical News: Pfizer has initiated the withdrawal of millions of Nurtec ODT Migraine tablet packs in the United States due to the lack of necessary child-resistant blister packs, which, according to U.S. regulators, present a poisoning hazard to children.
In all, more than four million blister packs of Pfizer’s prescription migraine drug Nurtec ODT is being recalled in Amer...