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Featuring latest Drug Developments and Treatment Protocols and also Updates about the Pharmaceutical Industry , both in Thailand and abroad, latest USFDA and Thai FDA approvals and also Corporate News with regards to various Pharma companies.
U.S. Medical News - Cancer Drug Shortage  Mar 17, 2023  2 years ago
U.S. Medical News: America Facing A Severe Shortage Of Various Cancer Drugs Including Methotrexate, Cisplatin, And Fluorouracil. Many Americans Will Die!   U.S. Medical News: The American Society of Health-System Pharmacists (ASHP) has issued warnings that the various cancer drugs are in shortage in the country including Injectable methotrexate, cisplatin, and fluor...
Medical Warnings - Online Influencers  Mar 14, 2023  2 years ago
Medical Warnings: A new study led by researchers from University of Colorado-USA has found that many online “Patient Influencers” are being paid by pharmaceutical companies to mislead viewers on prescription drugs!   In some cases, these online medical influencers are not just previous patients but also doctors, researchers and so called “experts’ and even advocacy o...
Colorectal Cancer - Bendectin  Mar 13, 2023  2 years ago
A new study by researchers from University of Texas Health Science Center at Houston (UTHealth Houston)-USA and the School of Public Health Public Health Institute, Berkeley, California-USA have shockingly found that all whose mothers had taken the anti-nausea drug called Bendectin during pregnancy face a high risk of developing colorectal cancer!   The study findings showed that prenatal e...
Pharma News - Apotex   Mar 09, 2023  2 years ago
Pharma News: Apotex, Canada's largest generic drug maker, has announced a recall of six batches of the glaucoma and ocular hypertension drug brimonidine tartrate ophthalmic solution due to sterility concerns. https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/apotex-corp-issues-voluntary-nationwide-recall-brimonidine-tartrate-ophthalmic-solution-015-due   The company is...
Pharma News - Sandoz Dicillin  Feb 24, 2023  2 years ago
Pharma News: The Danish Medicines Agency has initiated a recall of Sandoz’s Dicillin antibiotics after it was discovered that the drugs were contaminated and lead to users developing an infection involving Carbapenemase-Producing ST79 Enterobacter Hormaechei. https://laegemiddelstyrelsen.dk/da/nyheder/2023/antibiotikalaegemidlet-dicillin-fra-firmaet-sandoz-tilbagekaldes/   The recall ...
Drug News - Domperidone  Feb 01, 2023  2 years ago
Drug News: Health Canada has reported that is reviewing the safety of the drug Domperidone, a pharmaceutical compound that blocks dopamine to the brain and is often prescribed to aid with speeding up digestion. Domperidone (Motilium) is basically a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by o...
Medications-Drugs - Midazolam - Heart Injury - Chronotherapy  Dec 07, 2022  2 years ago
Medications - Drugs: A study by researchers from the Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado-United States has found that the usage of the sedative midazolam at night increases risk of myocardial injury and heart damage! https://www.dea.gov/sites/default/files/2020-06/Benzodiazepenes-2020_1.pdf   Midazolam, sold under the brand name Verse...
HIV News -Long Lasting PrEP Injectables  Dec 01, 2022  2 years ago
HIV News: A new injectable PrEP to combat HIV infections and can last for two months has entered the market but unfortunately the cost of the drug was deliberately aimed at HISO sluts and upmarket prostitutes as it cost about US$3,800 per dose or over US$22,000 per person per year in the United States!   The new injectable PrEP called CAB-LA or cabotegravir-long acting was developed and pat...
Pharma News - Ibuprofen - Naproxen  Nov 25, 2022  2 years ago
Pharma News: A new study lead by researchers from the Department of Radiology and Biomedical Imaging at the University of California, San Francisco- USA have found that the usage of pain relievers like Ibuprofen and Naproxen actually worsens arthritis inflammation.   The study team warns that the use of NSAIDS such as ibuprofen and naproxen might not have the desired effect patients are see...
Source: Medical News - Amoxicillin - United States  Nov 15, 2022  2 years ago
Due to the sudden shortage of the antibiotic Amoxicillin as oral tablets, powder suspension and especially in liquid form for intravenous use in the United States, Thailand Medical News has arranged for free disbursement of stocks to any hospitals, clinic or individuals needing it in the United States as our way of helping the American healthcare community.   A post-COVID-19 surge in upper ...
Source: Pharma News - Gepotidacin - UTIs  Nov 05, 2022  2 years ago
Pharma News: Pharma giant, GSK has developed a new antibiotic called Gepotidacin that could fight tough-to-treat drug resistance urinary tract infections (UTIs).   Phase 3 clinical trials proved to not only be successful but demonstrated the efficacy of the drug beyond the researchers’ expectations that the trials ended earlier than expected. https://www.gsk.com/en-gb/media/press-rele...
Source: Pharma News - Metformin - Atrial Fibrillation  Oct 12, 2022  2 years ago
A new study by researcher from Cleveland Clinic, Ohio-USA And Northwestern University-Illinois-USA has found that the common generic drug used to treat type 2 diabetes..metformin, can be used to treat atrial fibrillation. Atrial fibrillation (AF) is an irregular and often very rapid heart rhythm (arrhythmia) that can lead to blood clots in the heart. AF increases the risk of stroke, heart failure...
Source: Medical News - Pediatric Drugs  Oct 06, 2022  2 years ago
A worldwide alert has been issued over children cough and cold syrups that are made in India after more than 66 children died from these contaminated products and hundreds more were sickened by them.   The World Health Organization (WHO) issued the alert on Wednesday over four cough and cold syrups made by Maiden Pharmaceuticals in India, warning they are linked to the deaths of 66 children...
Source: Medical News -NSAIDs-Heart Failure  Sep 07, 2022  2 years ago
A new study by Danish researchers the Copenhagen University Hospital in Denmark has found that the usages of common NSAIDs (non-steroidal anti-inflammatory drugs) like Ibuprofen and Diclofenac by diabetics were linked to a higher risk of heart failure.   The study findings were presented during the recent European Society of Cardiology annual congress or ESC Congress 2022 and will be publis...
Source: Drug News - GLP-1 Receptor Agonists Drugs  Sep 05, 2022  2 years ago
Drug News: Medical researchers from the U.S FDA have discovered that diabetics taking glucagon-like peptide-1 (GLP-1) receptor agonists drugs like exenatide, dulaglutide, semaglutide and lixisenatide have a higher risk of developing acute cholecystitis and even higher risk of death!   The study team conducted a detailed meta-analysis from data of the of U.S FDA's reporting system for ad...
Source: Colchicine-Heart Failure  Jun 20, 2022  3 years ago
A new study by medical researchers from the University of Virginia-USA has found that the common and cheap drug that is used to treat gout- Colchicine, also helps improve the survival rates of heart failure patients. Considering that the incidences of heart failures has increased tremendously during the COVID-19 pandemic due to suspected links between the SARS-CoV-2 virus and the direct and indir...
Source: Thailand Medical -Molnupiravir-COVID-19  May 08, 2022  3 years ago
Despite growing reports by many physicians around the world about a variety of adverse effects from patients who are treated with molnupiravir, the mutagenic drug that was approved by the non-credible U.S. FDA to treat COVID-19 and as usual was adopted by the stupid health authorities from various countries that emulates everything that America does, the drug is still being used by many stupid doc...
Source: Cyproterone Acetate  Feb 05, 2022  3 years ago
A new study by researchers from University of Bristol-UK, National University of Singapore, University of Cambridge and Addenbrooke’s Hospital-UK and the National University Hospital-Singapore has alarmingly found that the hormone drug Cyproterone Acetate increases the risk developing benign brain tumors or meningiomas especially if used for long periods of time or in high doses. Cyproter...
Source: Blood Thinners-COVID-19  Oct 02, 2021  3 years ago
Blood Thinners-COVID-19: A new study by researchers from University of Minnesota-USA and Basel University-Switzerland has found that outpatients with COVID-19 who were on outpatient blood thinners at the time of diagnosis experienced a 43% reduced risk of hospitalization. The study focused on COVID-19 positive patients who have been taking prescribed anticoagulant class rugs including warfarin, a...
Source: Pulmonary Fibrosis  Sep 01, 2021  3 years ago
A new breakthrough study by researchers from University of Alabama at Birmingham-USA has found that the drug Venetoclax used to treat adult patients with Chronic Lymphocytic Leukemia (CLL) could be repurposed to reverse lung fibrosis after successful mouse model drug trials. Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymp...
Source: COVID-19 Drugs-Fluvoxamine  Aug 14, 2021  3 years ago
COVID-19 Drugs: Fluvoxamine, an inexpensive anti-depressant drug is now emerging as a potential candidate to be repurposed to treat COVID-19. Speculations are adrift that Canada might be the first country to approve its usage to treat COVID-19 followed by the United States, India, Brazil and South Africa.   Fluvoxamine, sold under the brand name Luvox among others, is an antid...
Source: COVID-19 Drugs  Jun 30, 2021  4 years ago
Remdesivir the controversial drug that was deemed to be ineffective in WHO’S SolidarityTrial (https://www.thailandmedical.news/news/latest-who-s-solidarity-drug-trial-shows-that-remdesivir-is-not-the-least-effective-in-treating-covid-19) but is still being approved as a drug to treat COVID-19 under EUA status in the United States by the no longer credible US FDA is now facing more backlash a...
Source: Cancer Drugs  Dec 18, 2020  4 years ago
Cancer Drugs: Pembrolizumab, an immunotherapy drug has been recently approved by the U.S. FDA  as a first-line treatment for patients with certain types of advanced colorectal cancer. This is the 9th FDA approval supported by Stand Up To Cancer® (SU2C) research. Individuals newly diagnosed with advanced or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (d...
Source: Pharma News  Nov 03, 2020  4 years ago
Pharma News: American biotech company that is linked to the corrupted Trump administration Regeneron, has another of its clinical trials halted over the weekend due to fatal adverse reactions to the monoclonal antibody drug garetosmab (REGN2477).   Only about 4 days ago, another clinical trial involving another monoclonal antibody drug to treat severe COVID-19 patients was also stopped due ...
Source: Drug News  Sep 25, 2020  4 years ago
Drugs News: A new study by researchers from the Universities of Edinburgh, Birmingham, Oxford and Nottingham have found the drug Gabapentin that is regularly used to treat chronic pelvic pain in women has been found to be no more effective than a placebo.   Chronic pelvic pain is estimated to affect 2–24% of women worldwide, and is associated with substantially reduced quality of life...
Source: HIV Drug News  Aug 15, 2020  4 years ago
HIV Drug News: Researchers at the George Washington University in a new study have discovered that Fingolimod, a US FDA-approved immunosuppressive drug used to treat multiple sclerosis flare-ups, may be used to effectively block HIV infection and reduce the latent virus reservoir.   The research findings were published in the journal: PLOS Pathogens. https://journals.plos.org/plospathogens/...
Source: TB Treatments  Aug 14, 2020  4 years ago
TB Treatments: New protocols involving the drugs Bedaquiline and Delamanid  for multidrug-resistant tuberculosis (MDR-TB) have shown early effectiveness in 85 percent of patients in a cohort that included many individuals with serious comorbidities that would have excluded them from clinical trials, according to the results of a new international study. The clinical trial results, based on...
Source: Diabetes And Canagliflozin  Aug 09, 2020  4 years ago
Diabetes And Canagliflozin: A serious drug interaction between canagliflozin (Invokana) and rosuvastatin (Crestor) was thought to cause liver and muscle toxicity (myotoxoicty) in a female patient in Canada, according to a new published case report. The case report was published in the medical journal: Annals of Internal Medicine as reported by Dr David Juurlink, MD, PhD, of Sunnybrook Health Sc...
Source: Multiple Sclerosis:   Aug 06, 2020  4 years ago
Multiple Sclerosis:  A recently completed phase 3, multicenter clinical trial has found that an immune-modulating drug can silence inflammatory disease activity in a large majority of patients with relapsing multiple sclerosis (RMS), the most common form of the illness, in which symptoms wax and wane.   Multiple Sclerosis or MS is an autoimmune disease in which the body's immu...
Source: Head Lice  Aug 04, 2020  4 years ago
Head Lice: A novel prescription head lice treatment, developed by University of Melbourne Associate Professor Dr Vern Bowles, has been given Food and Drug Administration (FDA) approval, allowing it to be sold in the U.S.   The new treatment, Xeglyze, was developed by Hatchtech, an Australian pharmaceutical company and will be commercialised by Dr. Reddy's Laboratories.   Hugh Alsop, ...
Source: Sports Medicine  Aug 04, 2020  4 years ago
Sports Medicine: Researchers from Western Norway University of Applied Sciences and the Norwegian University of Sport and Physical Education have discovered that a type of asthma drug, known as ß2-agonists, can boost sprint and strength performance in athletes who don't have the respiratory condition.   Their research findings have been published in the British Journal of Spo...
Source: Medicine Alert  Jul 24, 2020  4 years ago
Medicine Alert: Pennsylvania State University researchers along with scientists from La Jolla Institute for Immunology-California and Weill Cornell Medicine-Qatar, have found that in rats and human cells in vitro, LCCBs cause changes in blood vessels known as vascular remodeling that reduce blood flow and increase pressure and could potentially lead to heart failure.   The study finding...
Source: COVID-19 Warnings- Captopril  Jul 07, 2020  5 years ago
COVID-19 Warnings: A US based study involving researchers from University of Missouri Kansas City School of Pharmacy, Kansas State University and North Carolina State University has found that the high blood pressure drug Captopril to be associated with a higher rate of pulmonary adverse reactions in patients with diabetes than that of other ACE inhibitors or angiotensin receptor blockers (ARBs). ...
Source: Octreotide and Acromegaly  Jun 27, 2020  5 years ago
Octreotide and Acromegaly: The American Food and drug administration has approved the first and only oral form of somatostatin analog octreotide ( tradename: Mycapssa)  as a long-term maintenance therapy for individuals with acromegaly.   The drug Octreotide by Chiasma pharmaceuticals is the first product approved by the FDA using Chiasma's Transient Permeability Enhancer (TPE) tec...
Source: Multiple Sclerosis  Jun 18, 2020  5 years ago
Multiple Sclerosis: Medical researchers from the Kessler Foundation recently conducted a comprehensive review of pharmacologic agents used in the treatment of multiple sclerosis, seeking evidence for efficacy for the cognitive dysfunction experienced by more than half of affected individuals and found that most of the prescribed drugs do not work.   The research findings were published in the...
Source: Vildagliptin Versus Metformin  Jun 17, 2020  5 years ago
Vildagliptin an oral anti-hyperglycemic agent that goes by the trade name Galvus showed similar protective effects as metformin on the beta-cell function, reduced insulin resistance, and blood sugar levels in newly diagnosed Asian Indians with type 2 diabetes (T2D), according to a recent study. The research trial further found that there was an improved insulin sensitivity in patients treated wi...
Source: Pharmaceuticals  Jun 12, 2020  5 years ago
Pharmaceuticals: The US Food and Drug Administration has approved nivolumab (OPDIVO) by Bristol-Myers Squibb for patients with unresectable advanced, recurrent or metastatic esophageal squamous cell carcinoma (ESCC) after prior fluoropyrimidine- and platinum-based chemotherapy. Proof for efficacy was investigated in ATTRACTION-3 (NCT02569242), a multicenter, randomized (1:1), active-controlled,...
Source: Metformin and Diabetes  May 30, 2020  5 years ago
Metformin: The US FDA has issued warnings that many brands and versions of the drug Metformin that is used by diabetics in the US and around the world have been found to be contaminated with a carcinogenic compound called N-Nitrosodimethylamine.   The U.S. health regulators have started telling five drugmakers to recall their versions of a widely used diabetes medication after laboratory te...
Source: Thailand Medical News  Jan 03, 2020  5 years ago
In a latest development, the European Commission (EC) has approved Johnson & Johnson subsidiary Janssen’s Spravato (esketamine) nasal spray for treatment-resistant major depressive disorder. Spravato or Esketamine is an antagonist of the N-methyl-D-aspartate (NMDA) glutamate receptor and is similar in composition to illegal drug ketamine; Janssen has a risk management plan related to ...
Source: Thailand Medical News  Dec 14, 2019  5 years ago
Combined analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is effective and well-tolerated against advanced ROS1 and NTRK fusion-positive non-small cell lung cancers (NSCLC). Results of the trials STARTRK-1 (NCT02097810), STARTRK-2 (NCT02568267), and ALKA, show 77 percent response rate to entrectinib in 53 ...
Source: Thailand Medical News  Dec 11, 2019  5 years ago
A new research by pediatrics and migraine specialists from the University of Medical Sciences, Tehran show that Cinnarizine and Sodium Valproate are effective as the preventive agents of pediatric migraine in young children and teenagers. The study article entitled "Cinnarizine and sodium valproate as the preventive agents of pediatric migraine: A randomized double-blind placebo-controlled t...
Source: Thailand Medical News  Dec 02, 2019  5 years ago
Pharma Conglomerate, AstraZeneca  announced that the US Food and Drug Administration (FDA) has accepted a supplemental Biologics License Application (sBLA) and granted Priority Review for Imfinzi (durvalumab) for the treatment of patients with previously untreated extensive-stage small cell lung cancer (SCLC). Small Cell Lung Cancer is an aggressive, fast-growing form of lung cancer that r...
Source: Thailand Medical News  Nov 29, 2019  5 years ago
The US FDA (Food and Drug Administration) has approved South Korean company SK Chemicals’ patch-type Alzheimer’s drug, SID710.   The drug which has already secured approval in the European Union in 2013, is the generic version of Novartis’ Exelon Patch for the treatment of dementia symptoms associated with Alzheimer’s disease.   The approval marks the first time...
Source: Thailand Medical News  Nov 22, 2019  5 years ago
Thailand Pharma News The US FDA has granted supplemental approval to acalabrutinib (Calquence, AstraZeneca) for the treatment of adults with chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL).1 The Project Orbis, a collaboration between the United States, Australia, and Canada, provides a framework for concurrent submission and review of oncology pharmaceutical ap...
Source: Thailand Medical News  Nov 20, 2019  5 years ago
The US FDA (Food and Drug Administration ) has approved Fetroja (cefiderocol), an antibacterial drug for treatment of patients 18 years of age or older with complicated urinary tract infections (cUTI), including kidney infections caused by susceptible Gram-negative microorganisms, who have limited or no alternative treatment options. Dr John Farley, acting director of the Office of Infecti...
Source: Thailand Medical News  Nov 16, 2019  5 years ago
The US Food and Drug Administration approved Novartis AG's Adakveo (crizanlizumab) as new medicine that can help reduce extremely painful sickle cell disease flare-ups for patients 16 and older. The monthly infusion, which halves occurrences of sickle cell pain episodes, will carry a list price of roughly US$82,000 to US$114,000 per year, depending on dosing. Unfortunately, sickle cell dise...
Source: Thailand Medical News  Nov 10, 2019  5 years ago
The US FDA approved a record-breaking 59 novel drugs in 2018 for a range of diseases, bringing hope to scores of health sufferers around the world. This number was a more than twofold increase from a decade prior, which saw only 24 new drug approvals. And while this rise in the production and dissemination of new biological agents and products is good news for the advancement of global h...
Source: Thailand Medical News  Nov 09, 2019  5 years ago
The U.S. Food and Drug Administration has granted approval for Reblozyl (luspatercept-aamt) to be used for the treatment of anemia (lack of red blood cells) in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions. Dr Richard Pazdur, M.D., director of the US FDA's Oncology Center of Excellence and acting director of the Office of Oncologic Diseases in th...
Source: Thailand Medical News  Oct 26, 2019  5 years ago
New findings from the LIBERTY ASTHMA QUEST trial show that add-on dupilumab (Dupixent) showed symptomatic benefit for patients with both early-onset and later-onset uncontrolled asthma. In trial data published in the Chest Journal, the interleukin 4 and 13 (IL-4; IL-13) targeting monoclonal antibody showed an associated reduction of severe exacerbations and improved lung function in patien...
Source: Thailand Medical News  Oct 25, 2019  5 years ago
The US FDA has approved a new indication for the SGLT2 inhibitor canagliflozin made by Janssen Pharmaceuticals to reduce the risk for end-stage renal disease, worsening of kidney function, cardiovascular death and hospitalization for heart failure among adults with type 2 diabetes and diabetic kidney disease. Type 2 diabetes is the leading cause of kidney disease in the world, and the fifth fastes...
Source: Thailand Medical News  Oct 23, 2019  5 years ago
Trikafta (elexacaftor/ivacaftor/tezacaftor) from Vertex Pharmaceuticals is the first triple combination therapy to be approved by the US FDA and made available to treat patients with the most common cystic fibrosis mutation. Its list price is US$350,000 a year, same as one of the maker's earlier treatments for the genetic disease. Trikafta has been approved for patients aged 12 an...
Source: Thailand Medical News  Oct 22, 2019  5 years ago
A study by the London School of Hygiene & Tropical Medicine has shown that Tranexamic Acid, a low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury. The findings were published in the The Lancet. The researchers say that tranexamic acid, (TXA), a drug that prevents bleeding into the brain by inhibit...
Source: Thailand Medical News  Oct 20, 2019  5 years ago
A new flu drug by Genentech, Xofluza (baloxavir marboxil) has been granted US Food and Drug Administration (FDA) approval for a supplemental New Drug Application (NDA). The US FDA approval has been given for the indication of acute, uncomplicated influenza, or flu, in individuals aged 12 and older who have been symptomatic for no more than 48 hours and who are at high risk of developing flu-rela...
Source: Thailand Medical News  Oct 14, 2019  5 years ago
New study shows that ranitidine is an unstable molecule that breaks down under different conditions into the carcinogen N-nitrosodimethylamine (NDMA).   Online pharmacy Valisure is claiming that the Zantac is carcinogenic with N-nitrosodimethylamine (NDMA); that is a byproduct of the breakdown of the ranitidine molecule. The company, which performs its own testing on drugs it carries,...
Source: Thailand Medical News  Sep 23, 2019  5 years ago
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have discovered that Nilotinib (Tasigna), a drug used to treat chronic myeloid leukemia (CML) appears to be more effective at stopping a type of brain cancer called medulloblastoma in animal models than existing treatments for the deadly pediatric brain tumor.   Nilotinib is a type...

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