Medical News (World)

Viral Sepsis Challenges and New Insights

Nikhil Prasad Dec 17, 2024 7 days ago

Medical News: A Growing Health Concern Sepsis, often described as life-threatening organ dysfunction caused by a dysregulated response to infection, has long been a challenge in the medical field. Traditionally linked to bacterial and fungal infections, recent global viral outbreaks, such as those caused by COVID-19, MERS, and influenza viruses, have brought viral sepsis into sharper focus. Despi...

Discovery of Virus-Rich Cells in SARS-CoV-2 Infection

Nikhil Prasad Dec 17, 2024 7 days ago

Medical News: Researchers from Dongguk University in Seoul, Republic of Korea, have made groundbreaking discoveries about SARS-CoV-2, the virus responsible for COVID-19. Through an in-depth study, they have identified a new class of cells, termed virus-rich intermediate (VRI) cells, as central players in the virus’s infection dynamics within the human airway epithelium. The study covered in ...

German Researchers Explore Proteome Signatures in COVID-19 ICU Delirium Cases

Nikhil Prasad Dec 17, 2024 8 days ago

Medical News: In a groundbreaking study, researchers from Charité - Universitätsmedizin Berlin investigated the unique proteome signatures in COVID-19 patients who developed delirium during intensive care unit (ICU) treatment. Delirium, a condition marked by sudden confusion and cognitive impairment, is often observed in critically ill patients and can complicate recovery. By analyzing...

SARS-CoV-2 Causes Cathepsin-L Upregulation Which in Turn Raises Risk of Cancer and Tumor Progression!

Nikhil Prasad Dec 17, 2024 8 days ago

Thailand Medical News Exclusive: The COVID-19 pandemic caused by SARS-CoV-2 has reshaped global health, yet its implications extend beyond acute respiratory disease. Increasing evidence suggests that SARS-CoV-2 infection can influence pathways linked to cancer progression. One of the emerging connections is the upregulation of Cathepsin-L, a lysosomal cysteine protease, which plays a role in cellu...

Strategies for Managing Long COVID Through Pacing

Nikhil Prasad Dec 17, 2024 8 days ago

Medical News: Long COVID, medically referred to as Post-COVID Condition (PCC), continues to affect millions of individuals worldwide. This chronic multisystem condition is characterized by a spectrum of persistent symptoms that occur at least three months after a SARS-CoV-2 infection. Commonly reported symptoms include profound fatigue, post-exertional malaise (PEM), cognitive impairments, and sho...

Four New Cases of Mpox Clade 1b Found in Germany, Forcing School to Close

Nikhil Prasad Dec 17, 2024 8 days ago

Medical News: Authorities in Germany have reported four cases of the new Clade 1b variant of the Mpox (Monkeypox) virus. The infections were confirmed in a family residing in the western German town of Rösrath, located near Cologne. Among those affected are two school-age children who attend a special needs school in the area. Health officials believe the initial infection occurred after one ...

COVID-19 Hospitalizations in Western Australia Reaches 75 Per Day!

Nikhil Prasad Dec 17, 2024 8 days ago

Medical News: Western Australians Urged to Stay Home as COVID-19 Cases Surge Ahead of Christmas Western Australia is grappling with a concerning surge in COVID-19 cases, with authorities warning residents to take precautions as the holiday season approaches. The latest data reveals that an average of 75 people are being hospitalized daily due to COVID-19, putting additional pressure on the state&...

COVID-19 Causes Remodeling of the Pulmonary Vasculature!

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 virus, continues to reveal its many impacts on the human body. While much attention has been focused on its effects on the lungs and breathing, recent research now highlights how COVID-19 can drastically alter the pulmonary vasculature - the network of blood vessels in the lungs. This critical finding sheds li...

Discovery of Viral Hormones and Virally Encoded Growth Factors Opens New Dimensions in Virology, Endocrinology and Medicine

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: Groundbreaking Findings Unveil a New Paradigm in Science In an exciting development that could revolutionize medicine and biology, a team of international researchers has uncovered that certain viruses carry genes encoding molecules similar to human hormones and growth factors. This groundbreaking discovery sheds light on previously unknown interactions between viruses and human phy...

Deadly Pneumococcal Outbreak Grips Australia

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: Escalating Cases Reach 20-Year High Australia is facing its worst outbreak of pneumococcal disease in two decades, with over 4,500 severe cases reported in the past 24 months. The situation has drawn significant concern from health experts and advocacy groups, who are urging the government to accelerate the rollout of newer, broader-coverage pneumococcal vaccines. These vaccines, al...

Fusion Peptide of SARS-CoV-2 Unveiled as a Key Agent in Membrane Disruption

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: The SARS-CoV-2 virus has been under relentless scrutiny since the outbreak of the COVID-19 pandemic. Scientists worldwide have focused on understanding the mechanisms that enable the virus to invade human cells. Among the most critical steps in this process is membrane fusion, a mechanism by which the virus merges its lipid envelope with the membrane of a host cell. This essential st...

Detrimental Effects of Anti-Nucleocapsid Antibodies in COVID-19

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: The COVID-19 pandemic has affected millions worldwide, with the virus and its variants continuing to challenge medical professionals. Researchers Emi E. Nakayama and Tatsuo Shioda from the Department of Viral Infections at Osaka University’s Research Institute for Microbial Diseases in Japan, have delved into how certain immune responses, specifically anti-nucleocapsid antibodi...

Chronic Antihistamine Use Linked to Lower Risk of COVID-19 Severity and COVID-19 Mortality

Nikhil Prasad Dec 16, 2024 8 days ago

Medical News: In an unexpected development from a recent study, researchers have discovered that chronic use of antihistamines could significantly lower the risk of severe COVID-19 outcomes. This finding emerged from a detailed analysis conducted in Spain, where COVID-19 cases and hospitalization rates were examined closely among individuals with chronic medical prescriptions. Patients on antihist...

New Discovery Links Loss of Smell in COVID-19 to Epigenetic Changes

Nikhil Prasad Dec 16, 2024 9 days ago

Medical News: The loss of smell, medically known as anosmia, has been one of the most talked-about symptoms of COVID-19 since the early days of the pandemic. Many people who got infected by the SARS-CoV-2 virus reported this symptom, with some recovering their sense of smell in weeks, while others faced prolonged anosmia for months or even years. For those affected, this condition significantly im...

U.S. NIH Study Discovers Q226L Mutation Which Enhances Binding to Human Cells in H5N1 Virus Strain Isolated in Texas

Nikhil Prasad Dec 16, 2024 9 days ago

Medical News: Alarming Mutation in H5N1 Virus Raises Concerns About Pandemic Potential In a groundbreaking discovery, a U.S. National Institutes of Health (NIH)-funded study has identified a specific genetic mutation in the H5N1 avian influenza virus that enhances its ability to bind to human cells. This finding, centered around the Q226L mutation, was observed in a strain of the virus isolated f...

Toxicity Concerns of COVID-19 Antiviral Drugs on the Environment

Nikhil Prasad Dec 16, 2024 9 days ago

COVID-19 News: The COVID-19 pandemic brought unprecedented challenges to global health systems and societies, leading to the rapid development and increased use of antiviral drugs. While these drugs saved countless lives, their potential environmental impacts have raised significant concerns. A recent study by researchers from the University of Zagreb’s Faculty of Chemical Engineering and Te...

High Prevalence of Autoimmune Issues Found in Those with Post-Acute COVID Vaccination Syndrome

Nikhil Prasad Dec 16, 2024 9 days ago

Medical-News: The COVID-19 pandemic brought an unprecedented global health challenge, necessitating the rapid development and deployment of vaccines. However, many individuals have experienced unexpected adverse effects. Among these are cases resembling post-acute COVID-19 syndrome (PACS), but occurring in vaccinated individuals. This emerging condition, termed post-acute COVID vaccination syndrom...

Eastern Equine Encephalitis Virus and Its Impact on Human Health

Nikhil Prasad Dec 15, 2024 9 days ago

Medical News: Eastern equine encephalitis virus (EEEV) is a rare but serious virus transmitted through mosquito bites. Its primary hosts are birds, but it can spread to humans and horses, leading to potentially fatal outcomes. The disease is caused by a virus of the Togaviridae family, genus Alphavirus, and poses significant public health challenges due to its neurological effects and unpredictabl...

Taiwanese Study Finds That PM2.5 Particles in Polluted Air Increases Risk of COVID-19 Infection

Nikhil Prasad Dec 15, 2024 9 days ago

Medical News: Researchers from the National Yang Ming Chiao Tung University in Taiwan have provided groundbreaking insights into how particulate matter 2.5 (PM2.5) air pollution influences the risk of COVID-19 infections. PM2.5 consists of microscopic solid and liquid particles suspended in the air, small enough to penetrate deep into the lungs, causing serious health issues. This Medical News rep...

American Scientists Discover That Transposons Regulate Interferon Signaling During SARS-CoV-2 Infection

Nikhil Prasad Dec 15, 2024 9 days ago

Medical News: A groundbreaking study by researchers from the University of Colorado Boulder, Fred Hutchinson Cancer Research Center, Johns Hopkins University, and other leading institutions has unveiled new insights into how transposable elements, often referred to as "jumping genes," influence the human immune system. Their research sheds light on the role of transposons in the regulati...

Louisiana Reports First Possible Human Case of H5N1

Nikhil Prasad Dec 15, 2024 10 days ago

Medical News: A potential human case of bird flu, also known as H5N1, has been reported in Louisiana, marking the first known instance in the state. The Louisiana Department of Health announced that the affected individual, a resident of southwestern Louisiana, is currently hospitalized after exposure to sick and dead birds suspected of carrying the virus. This alarming development highlights ongo...

H5N1 Bird Flu Adaptation in Cats in South Dakota as a Lethal Neurotrophic Virus Raises Alarms

Nikhil Prasad Dec 15, 2024 10 days ago

Medical News: Virus adapted to target the brains of cats aggressively In recent years, a dangerous form of bird flu known as the highly pathogenic avian influenza H5N1 virus has rapidly spread across various parts of the world, infecting not only birds but also an expanding list of mammals. Initially detected in poultry and wild birds, this strain eventually made its way into animals such as foxe...

Glutamyl Aminopeptidase (APA), Encoded by the Gene ENPEP Could Be Another Human Receptor for SARS-CoV-2

Nikhil Prasad Dec 15, 2024 10 days ago

Medical-News-The fight against COVID-19 has propelled research into uncharted territories. Scientists from Tampere University and the University of Oulu in Finland have unveiled findings suggesting that glutamyl aminopeptidase (APA), encoded by the ENPEP gene, might serve as another receptor for SARS-CoV-2. Known primarily for its role in the renin-angiotensin-aldosterone system (RAAS), APA could ...

Moslae Herba as a Potential Herbal Remedy for COVID-19

Nikhil Prasad Dec 15, 2024 10 days ago

Medical News: As the world continues to combat the evolving threat of SARS-CoV-2, researchers are exploring alternative treatments to complement existing vaccines and antiviral drugs. Among the latest findings is the potential of Moslae Herba (MH), a traditional Chinese herbal medicine known for its antiviral and immune-boosting properties. Researchers from the Zhejiang Provincial Center for Disea...

Dysfunctions in the Vagus Nerve, Hypothalamic-Pituitary-Adrenal Axis and Mitochondria Underlie the Complexities of Long COVID

Nikhil Prasad Dec 14, 2024 10 days ago

Medical News: Long COVID is a complex and often debilitating condition that continues to affect millions of people worldwide. Defined by lingering symptoms lasting for months - or even years - after recovery from the initial SARS-CoV-2 infection, it has become a global health concern. The symptoms of long COVID range from fatigue and brain fog to respiratory issues and cardiac dysfunction, affecti...

U.S. NIH Study Finds That SARS-CoV-2 Infection of the Salivary Glands Causes Weakening of Antifungal Defenses

Nikhil Prasad Dec 14, 2024 10 days ago

Medical News: Researchers have uncovered critical insights into how SARS-CoV-2, the virus responsible for COVID-19, affects oral health. Conducted by teams from the National Institutes of Health (NIH)-USA and the University of Maryland-USA, this groundbreaking study highlights how SARS-CoV-2 infection compromises salivary gland functions, leading to a decrease in an important antifungal protein ca...

Czech Republic Scientists Discover the Zymogenic Form of the SARS-CoV-2 Main Protease for Drug Targeting

Nikhil Prasad Dec 14, 2024 11 days ago

Medical News: A groundbreaking study by scientists from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Charles University, and the University of Chemistry and Technology in Prague introduces a new avenue in COVID-19 treatment. The research focuses on the zymogenic (inactive precursor) form of the SARS-CoV-2 main protease (Mpro), a pivotal enzyme in the virus&...

Researchers Warn That COVID-19 May Contribute to the Development of Thyroid Cancer

Nikhil Prasad Dec 14, 2024 11 days ago

Medical News: Polish researchers from Wroclaw Medical University, alongside colleagues from the Hirszfeld Institute of Immunology and Experimental Therapy and Wroclaw University of Science and Technology, have proposed a startling hypothesis that COVID-19 could play a role in the development of thyroid cancer. This groundbreaking revelation has emerged from a comprehensive review. The study review...

67.9 Percent of Patients Who Had Severe COVID-19 Pneumonia Have Evidence of Fibrosis Three Months After Discharge

Nikhil Prasad Dec 14, 2024 11 days ago

Medical News: The Impact of COVID-19 Beyond Recovery The COVID-19 pandemic has not only brought a wave of acute illnesses but also a range of persistent health challenges. One of the most concerning long-term effects is post-COVID pulmonary fibrosis - a condition where scarring in the lungs can impair respiratory function. Researchers from the University of Medicine and Pharmacy Carol Davila and ...

Quercetin as a Potential Treatment for Fatty Liver Disease

Nikhil Prasad Dec 13, 2024 11 days ago

Medical News: Non-alcoholic fatty liver disease (NAFLD) is emerging as a significant global health challenge. Characterized by the accumulation of excess fat in the liver, it affects approximately 30% of the world's population and is projected to increase further due to sedentary lifestyles and unhealthy diets. In its more severe form, non-alcoholic steatohepatitis (NASH), it can lead to irrev...

Key Predictors of Sepsis in Hospitalized COVID-19 Patients

Nikhil Prasad Dec 13, 2024 11 days ago

Medical-News: A recent investigation, conducted jointly by researchers from Mansoura University and Kafr Elsheikh Chest Hospital in Egypt, sheds light on one of the most alarming complications in COVID-19 cases: sepsis. Sepsis, a life-threatening condition triggered by the body's uncontrolled response to infection, remains a critical challenge for healthcare systems worldwide. This Medical New...

Researchers Discover Role of TRIF and TAK1 in Influenza A Virus Pyroptosis

Nikhil Prasad Dec 13, 2024 11 days ago

Medical News: Influenza Research Highlights Cell Death Mechanisms Influenza A virus (IAV) continues to be a formidable health challenge, causing seasonal epidemics and occasional pandemics. It is a segmented single-stranded RNA virus, primarily targeting respiratory tract epithelial cells. The body's immune system combats this virus using several mechanisms, including programmed cell death. A...

Importance of Dietary N6 Fatty Acids for The Brain Health of Middle-Aged and Elderly Adults

Nikhil Prasad Dec 13, 2024 11 days ago

Medical News: A recent study conducted by researchers from Shanghai Jiao Tong University School of Medicine, the National Center for Mental Health in Beijing, and Xi'an Jiaotong-Liverpool University in Suzhou-China explored the intricate relationship between dietary omega-6 (n-6) polyunsaturated fatty acids (PUFAs) and brain health. The study targeted middle-aged and elderly populations, empha...

Natural Phytochemicals from Helichrysum Populifolium Tackles Antibiotic Resistance in Gonorrhea

Nikhil Prasad Dec 13, 2024 11 days ago

Medical News: The alarming rise in antibiotic-resistant Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, has left healthcare systems grappling for solutions. Over 87 million cases of gonorrhea are reported annually worldwide, according to the World Health Organization (WHO), with resistance to current treatments posing a significant challenge. The bacteria’s ability to resist c...

High Dose Vitamin C as a Potential Ally Against Tendon Cell Degeneration

Nikhil Prasad Dec 13, 2024 11 days ago

Medical-News: Tendon injuries are not uncommon, especially among aging populations. While young individuals often experience tendon damage due to severe trauma, even minor strains can lead to tendon ruptures in older adults. This difference arises largely because of age-related degeneration in tendons and ligaments. Such degeneration can manifest in various tendons, including the Achilles tendon, ...

New Strain of Mumps Virus Wreaking Havoc in Kerala?

Nikhil Prasad Dec 13, 2024 12 days ago

Medical News: Mumps Outbreak Among School Students Sparks Concern Kerala is currently grappling with a sudden spike in mumps cases, particularly among school-aged children. In Thiruvananthapuram alone, over fifty new cases are being reported daily, sending alarm bells ringing in the health sector. The highly contagious viral disease, which traditionally impacts younger children, is now spreading ...

The Core Network in SARS-CoV-2 and Its Role in RNA Binding

Nikhil Prasad Dec 13, 2024 12 days ago

Medical News: Scientists from Goethe University in Frankfurt, Columbia University in New York, Deutsches Elektronen-Synchrotron in Hamburg, and the University of Greifswald have unraveled critical insights into the SARS-CoV-2 nucleocapsid protein. This protein, essential for the virus’ RNA genome processing, plays a pivotal role in the virus’ ability to survive, replicate, and spread. ...

Post COVID-19 Depression and Its Links to TNF-Alpha

Nikhil Prasad Dec 13, 2024 12 days ago

Medical News: Understanding Post COVID Depression The COVID-19 pandemic has left a significant impact on both physical and mental health across the globe. While much attention has been given to the respiratory and systemic effects of the virus, emerging research highlights the psychological aftermath, particularly depression, in individuals recovering from the illness. A study conducted by resear...

German Doctors Warn That Those Having or Had COVID-19 Should be Careful When Using a Sauna

Nikhil Prasad Dec 12, 2024 12 days ago

Medical News: For centuries, sauna bathing has been celebrated as a therapeutic practice that promotes relaxation and health benefits. Across the world, millions frequent saunas to relieve stress, enhance vascular health, and soothe aching muscles. However, a recent case report from Germany reveals that sauna use might pose serious health risks for individuals who currently have or have recently r...

Harvard Scientists Warn That Evolution of SARS-CoV-2 Variants Challenges mRNA Vaccines

Nikhil Prasad Dec 12, 2024 12 days ago

Medical News: As the world continues to grapple with the ongoing presence of COVID-19, researchers have delved deeper into understanding how the virus evolves and escapes immunity provided by vaccines. A study spearheaded by teams from prestigious institutions such as the Ragon Institute of MGH, MIT, Harvard, Massachusetts General Hospital, and Brown University sheds light on this pressing issue. ...