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Source: PAREXEL  Nov 12, 2018
After two chimeric antigen receptor (CAR) T-cell therapies won FDA approval in 2017 to treat children and young adults with acute lymphoblastic leukemia (ALL) and adults with diffuse large B-cell lymphoma, the American Society of Clinical Oncology hailed CAR T-Cell Immunotherapy as the Advance of the Year.1 Complete remission/response rates in clinical trials for these medicines (both targeting th...
Source: Thermo Fisher Scientific  Nov 11, 2018
Biologics have experienced steady double-digit growth over the last 15 years and now comprise slightly more than a quarter of all New Molecular Entity (NME) FDA approvals. Similarly, EvaluatePharma’s 2017 report on orphan drugs projects that by 2020, six of the 10 best-selling global drug therapies will be biologic sterile injectable drugs. Precision medicine is also on the rise, with the FD...
Source: AstraZeneca  Oct 11, 2018
Metastatic breast cancer is cancer that has advanced and spread beyond the breast and regional lymph nodes to other parts of the body. Around 20–50% of patients diagnosed with primary breast cancer will develop metastatic disease and up to 19% of patients with breast cancer already had metastatic disease when they were first diagnosed. Treatments for metastatic breast cancer aim to allevia...