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Source: University of Colorado Anschutz Medical Campus  May 09, 2019  6 years ago
A mysterious epidemic of chronic kidney disease among agricultural workers and manual laborers may be caused by a combination of increasingly hot temperatures, toxins and infections, according to researchers at the University of Colorado Anschutz Medical Campus. In recent years, chronic kidney disease has emerged as a major illness among workers in hot climates. It was first identified in the 1...
Source: US FDA  May 08, 2019  6 years ago
If you have type 2 diabetes and are taking a newer class of medications to treat your disease—but one day you notice pain, redness and a foul odor in your genital area.If this happens, new research suggests you need to see your doctor immediately, because you may be suffering from Fournier gangrene. Also known as a "flesh-eating" disease, this infection attacks your genital or anal...
Source: Institute of Cancer Research, UK  May 07, 2019  6 years ago
Scientists have identified a gene mutation in the tumours of men with prostate cancer that is linked to very poor survival—and which could be used to pick out patients for more intensive treatment. Men with mutations in the retinoblastoma gene in their tumours were more than three times as likely to die and nearly seven times as likely to relapse on standard treatments as those without th...
Source: PLOS  May 06, 2019  6 years ago
Paromomysin-based topical treatments were shown to be effective in curing cutaneous leishmaniasis (CL), according to a randomized, double blind study conducted in Central America and published with PLOS Neglected Tropical Diseases. Leishmaniasis, transmitted by a female phlebotomine sand fly bite, is endemic in 98 countries and has approximately 0.7 to 1.2 million CL cases each year. Infectio...
Source: Karolinska Institutet  May 05, 2019  6 years ago
Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer. The researchers envision that this discovery may eventually result in a test that contributes to a more personalised treatment of the disease. Prostate cancer is the most common male cancer in Sweden. App...
Source: University of Oxford  May 04, 2019  6 years ago
The discovery of a new way to target and treat the leading genetic contributor to Parkinson's may open the way for a potential new clinical treatment. Researchers from Oxford's Department of Physiology, Anatomy and Genetics (DPAG) have identified how the dysfunction of a key gene, LRRK2, causes the neurons affected in Parkinson's to lose their ability to effectively clear out cell c...
Source: Rice University  May 03, 2019  6 years ago
Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues.   Bioprinting research from the lab of Rice University bioengineer Jordan Miller featured a visually stunning proof-of-principle -- a scale-model of a lung-mimicking air sac with airways and blood vessels that never touch yet still provide oxygen to re...
Source: National Institutes of Health,US  May 02, 2019  6 years ago
Taking a folic acid supplement daily before pregnancy may reduce the risk of gestational, or pregnancy-related, diabetes, according to a study by researchers at the National Institutes of Health and other institutions.    Folic acid is the synthetic form of folate, or vitamin B9, which is found in leafy green vegetables, nuts, peas, beans and other foods. The U.S. Preventive Services T...
Source: Novartis  May 01, 2019  6 years ago
  Collaboration covers proposed trastuzumab biosimilar in Phase III development for human epidermal growth factor receptor 2 positive (HER2+) breast and gastric tumors Per licence agreement, EirGenix, Inc is responsible for development and manufacturing; Sandoz has right to commercialize in all markets except China and Taiwan Agreement is third announced biosimilars collaboration for San...
Source: Thailand Medical News  May 01, 2019  6 years ago
Hua Chiew Hospital recently conducted a Free Diabetic workshop for patients and individuals interested in diabetes prevention and  management. The workshop covered topics including blood sugar monitoring, educational aspects of the disease. Food and diet management, types of treatment protocols and drugs available and also covered aspects of neuropathic ailments and also gangrene dangers and ...
Source: Medical University of South Carolina  May 01, 2019  6 years ago
Peppermint can help with the difficulty swallowing and non-cardiac chest pain experienced by some patients with disorders of the esophagus, report investigators at the Medical University of South Carolina. Of the 38 patients enrolled in the MUSC pilot study, 63 percent overall reported improvement of symptoms. Patients were recruited from the Esophageal Disorders Clinic at the MUSC Health Digestiv...
Source: US FDA  May 01, 2019  6 years ago
The U.S. Food and Drug Administration approved Benlysta (belimumab) intravenous (IV) infusion for treatment of children with systemic lupus erythematosus (SLE) - often referred to as simply "lupus" - a serious chronic disease that causes inflammation and damage to various body tissues and organs. This is the first time that the FDA has approved a treatment for pediatric patients with SLE...
Source: Acutus Medical  May 01, 2019  6 years ago
Acutus Medical, a California based company, won European clearance for its AcQMap contact mapping software. The company also won FDA approval for its second generation AcQMap platform .   The technology, used during cardiac ablation procedures, creates volumetric images of the atrial anatomy using ultrasound At the same time, contact-free charge density is used to generate high-definition 3...
Source: University of Texas Health Science Center at San Antonio  May 01, 2019  6 years ago
Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced at the Pediatric Academic Societies 2019 meeting in Baltimore, Md.  Study coauthor Jane Lynch, M.D., FAAP, professor of pediatrics at UT Health San Antonio, said the drug, liraglutide, in combination with an existing medication, metformin, showed robust effect in treating chi...
Source: Stanford University Medical Center  Apr 30, 2019  6 years ago
People suffering from a debilitating and often discounted disease known as chronic fatigue syndrome may soon have something they've been seeking for decades: scientific proof of their ailment. Researchers at the Stanford University School of Medicine have created a blood test that can flag the disease, which currently lacks a standard, reliable diagnostic test. "Too often, this diseas...
Source: Proceedings froms ESTRO 2019, Milan  Apr 29, 2019  6 years ago
A single high dose of radiation that can be delivered directly to the tumour within a few minutes is a safe and effective technique for treating men with low risk prostate cancer, according to a study presented at the ESTRO 38 conference. Radiotherapy traditionally involves a series of lower dose treatments that take place over several days or week. The new treatment is called high dose-rate br...
Source: Proceedings froms ESTRO 2019, Milan  Apr 28, 2019  6 years ago
For females with hormone-driven breast cancer, adding radiation to hormone therapy might keep their cancer from coming back for up to a decade, a new study finds. Breast cancer didn't come back in the same breast for 97.5% of women who had radiation therapy plus hormone therapy compared to just over 92% of women who had hormone therapy alone, the researchers said. In addition, over the stu...
Source: Sanofi  Apr 27, 2019  6 years ago
French pharmaceutical giant Sanofi on Friday said the European Medicines Agency had conditionally approved its anti-cancer drug Libtayo, the first drug of its kind to be authorised for use in the EU. The drug, also known as CEMIPLIMAB-RWLC is used for for treatment of Advanced Cutaneous Squamous Cell Carcinoma The tumour-reducing drug is aimed at patients with the second most common form of ski...
Source: Uppsala University  Apr 27, 2019  6 years ago
Many diabetes patients do not only have problems with their insulin, but also with the release of the hormone glucagon. Researchers at Uppsala University have now discovered a regulation mechanism which could provide an opportunity to improve blood glucose control in these patients. The hormone glucagon, which is released from alpha cells in the pancreas, plays a vital role in blood glucos...
Source: Thomas Jefferson University  Apr 26, 2019  6 years ago
A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation—an early indication that the vaccine could activate immune cells to fight colorectal tumors and metastases. Further tests to determine if th...
Source: European Society of Cardiology  Apr 25, 2019  6 years ago
Women who take antibiotics over a long period of time are at increased risk of heart attack or stroke, according to research carried out in nearly 36,500 women.   The study found that women aged 60 or older who took antibiotics for two months or more had the greatest risk of cardiovascular disease, but long duration of antibiotic use was also associated with an increased risk if taken ...
Source: American College of Physicians  Apr 24, 2019  6 years ago
In the Diabetes Prevention Program (DPP) clinical trial and its long-term follow-up study, among the persons who lost at least 5 percent of their body weight during the first year, long-term maintenance of weight loss was more likely if they had been assigned to treatment with metformin than with placebo or lifestyle intervention. Being older and losing a greater amount of weight in the first year...
Source: Vanderbilt University Medical Center  Apr 23, 2019  6 years ago
Diabetes has reached epidemic proportions in Asia and has dramatically increased the risk of premature death, especially among women and middle-aged people, a multinational study led by Vanderbilt University researchers has found. There is an urgent need to implement diabetes management programs tailored to Asian populations."We found that patients with diabetes are at a substant...
Source: MOPH  Apr 22, 2019  6 years ago
The Thai Food and Drug Administration has announced that Self  HIV Test Kits are now available for all to purchase at participating pharmacy outlets. Dr Tares Krassanairawiwong, the FDA Secretary general also said that individuals that have positive reactive  test should immediately contact a doctor or nearby medical hospital of licensed clinic to get appropriate medical advice There ...
Source: University of Pennsylvania  Apr 22, 2019  6 years ago
Whether a wound -- such as a diabetic foot ulcer -- heals or progresses to a worse outcome, including infection or even amputation, may depend on the microbiome within that wound. A new study from the Perelman School of Medicine at the University of Pennsylvania found specific strains of the common pathogen Staphylococcus aureus (S. aureus) are associated with wounds that do not heal. Researc...
Source: Beth Israel Deaconess Medical Center  Apr 21, 2019  6 years ago
About one in seven women in the world will develop breast cancer in her lifetime. The vast majority of these cancers depend on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone's effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer to recur o...
Source: Thailand Medical News  Apr 20, 2019  6 years ago
From new toxins to new thoughts on duration of effect to micro injections, the toxin market is growing in dermatology.(exclusive interview with Dr . Michael Gold)   The toxin market is growing for aesthetic indications, and patient interest continues to soar. But in addition to a growing market, Dr. Michael Gold, a leading Dermatologists in the US  says there are other trends to watch....
Source: The Ohio State University  Apr 20, 2019  6 years ago
Researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have developed a novel stroke therapy that, when tested in mice and dogs, has proven superior to the standard of care therapy now offered to patients suffering a stroke. "We have shown that our drug, which is completely reversible, opens up a blocked blood vessel better than the...
Source: Thailand Medical News  Apr 19, 2019  6 years ago
President Trump just signed into law the “Special Registration for Telemedicine Act ” (the Act), requiring the Drug Enforcement Administration (DEA) to activate a special registration allowing physicians and nurse practitioners to prescribe controlled substances via telemedicine without an in-person exam. The DEA has no more than one year to complete the task.   Until now, the f...
Source: Thailand Medical News  Apr 19, 2019  6 years ago
As usual, our advice from the team at Thailand Medical News is to focus on the US stock markets rather than the local stocks due to a variety of reasons. The US stock market looks as promising as ever especially when it comes to healthcare and biotech stocks. The U.S. soon will spend nearly 20% of its gross domestic product on health care. This comes as health care costs outpace the rise...
Source: Oregon Health & Science University  Apr 19, 2019  6 years ago
A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at Oregon Health & Science University have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord.   The discovery, involving mice genetically engineered to mimic multiple sclerosis, published in the journal&nbs...
Thailand Medical News  Apr 18, 2019  6 years ago
Commonly called Bai Bua Bok in Thai, its scientific name is Centella asiatica. Some also call it spadeleaf, Jal Bahmi, Asiatic pennywort, Indian pennywort, or hydrocotyle. Still, its most popular name is gotu kola.   Belonging to the family of carrots, gotu kola is a perennial creeping herb, growing in dark and moist climates of Thailand ,South Africa, Indonesia, Australia, China,...
Source: Thailand Medical News  Apr 18, 2019  6 years ago
What can you do to prevent stroke? Age makes us more susceptible to having a stroke, as does having a parent or other close relative who has had a stroke. You can't reverse the years or change your family history, but there are many other stroke risk factors that you can control—provided that you're aware of them. If you know that a particular risk factor is sabotaging your health...
Source: NIH/National Institute of Allergy and Infectious Diseases,US  Apr 18, 2019  6 years ago
Regular infusions of an antibody that blocks the HIV binding site on human immune cells may have suppressed levels of HIV for up to four months in people undergoing a short-term pause in their antiretroviral therapy (ART) regimens, according to a report published online today in The New England Journal of Medicine. Results of the Phase 2, open-label study indicate the antibody, known as UB-42...
Source: AZ Urogynecology and Pelvic Health Center  Apr 17, 2019  6 years ago
Interstitial Cystitis (IC) is a medical disorder where patients experience urgent and frequent urination and bladder pain in absence of a bladder infection. IC symptoms can result in poor quality of life with depression, sexual dysfunction, anxiety, sleep dysfunction, and stress.   Typically, patients will suffer with painful urination, bladder pain, urgent or frequent urination and even af...
Source: Thermo Fisher Scientific  Apr 17, 2019  6 years ago
Thermo Fisher Scientific, the world leader in serving science, today announced the availability of the Thermo Scientific CEDIA Mitragynine (Kratom) Assay, its newest drugs of abuse test that includes supporting calibrators and controls. The CEDIA Mitragynine (Kratom) Assay can be run on commonly used clinical chemistry analyzers, allowing a broad spectrum of laboratorians to test for the presenc...
Source: University Of Otago  Apr 17, 2019  6 years ago
Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that. Researchers from the University of Otago, New Zealand, and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different in oral cancer tissues compared to the adjacent healthy tissues in...
Source: Stanford Medicine  Apr 16, 2019  6 years ago
A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease. "For the first time in 18 years, we have a therapy for patients with Type 2 diabetes and chronic kidney disease that decreases kidney failure," said Kenneth Mahaffey, MD, professor of medicine at the Stanford University School of Medicine and co...
Source: University of California - San Diego  Apr 15, 2019  6 years ago
Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To help keep tabs on inflammation, immune cells employ a molecular machine called the NLRP3 inflammasome. NLRP3 is inactive in a healthy cell, but is switched "on" when ...
Source: American Society of Nephrology  Apr 14, 2019  6 years ago
New research reveals that pruritus, or itchy skin, affects a substantial percentage of patients with chronic kidney disease (CKD). The study, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology(CJASN), also indicates which patients are more likely to experience pruritus, and demonstrates that pruritus may affect quality of life and sleep. In stud...
Source: University of Edinburgh   Apr 13, 2019  6 years ago
Researchers say patients should continue to take the drugs, which are commonly prescribed to older men, but warn they may need additional health checks. The team stressed that current treatment guidelines do not need to change, based on their study of patient health records. Men with enlarged prostates are commonly prescribed drugs called 5-alpha-reductase inhibitors that reduce the production ...
Source: University Of Michigan  Apr 12, 2019  6 years ago
Human papillomavirus infection rates are increasing in women born after 1980 who did not receive the HPV vaccine—putting them at higher risk for HPV-related cancers, according to a University of Michigan study. While more than 90 percent of HPV-related cancers are preventable, HPV causes more than 40,000 cases of cancer in the United States each year and about 1.8 million cases globally, ...
Source: Pasteur Institute  Apr 11, 2019  6 years ago
Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals. Scientists at the Institut Pasteur working in collaboration with the CNRS have demonstrated that a cellular protein is capable of acting as a ...
Source: Thailand Medical News  Apr 10, 2019  6 years ago
Dealing with multinational insurance companies can often be a nightmare proposition in Thailand, for expats and tourists alike. Provider networks are often limited. Insured patients must usually pay bills upfront with the promise of reimbursement by the insurer later, which either comes months later or not at all. Necessary medical care is often denied because of technicalities.  Structural F...
Source: The Translational Genomics Research Institute  Apr 09, 2019  6 years ago
Hepatocellular carcinoma (HCC) is a long medical name for the most common form of liver cancer, a malignancy whose incidence has nearly doubled over the past decade, making it the fastest growing type of cancer in the U.S., and the third-leading cause of cancer-related death worldwide. Researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, provide the...
Source: BNH Hospital  Apr 08, 2019  6 years ago
BNH Hospital recently hosted  a seminar on the topic of “The Incredible Power of Cell Therapy for pain-free movement” under the cooperation with Avenue Cell Clinic, the leading medical institution in Japan specialising in regenerative medicine with the use of cell treatment. Nopparat Panthongwiriyakul, MD., Deputy Director of BNH hospital gave an opening speech.&nb...
Source: Thailand Medical News  Apr 08, 2019  6 years ago
This article has been specially commissioned by Thailand Medical News to bring about awareness and also create caution about the excessive usage of PPIs (Proton Pump Inhibitors) that is over prescribed currrently in Thailand to treat acid reflux conditions. A recent landmark population study by US researchers at the University of California -- San Diego has indicated that Proton pump inhibitors ...
Source: University of Michigan  Apr 07, 2019  6 years ago
A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial. The shot, a therapeutic vaccine, injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraep...
Source: McGill University  Apr 06, 2019  6 years ago
Researchers have known  that inflammation accompanies Alzheimer's disease (AD) brain lesions. Several early studies suggested that "super-aspirins" or Nonsteroidal anti-inflammatory drugs (NSAID) could help avoid the disease. However, after clinical trials showed that NSAIDs don't help patients who already have AD symptoms, doctors wondered whether these drugs could still be...
Source: The London School of Medicine (Blizard Institute)  Apr 05, 2019  6 years ago
A recent research found that long-term cotrimoxazole treatment reduces mortality and morbidity in children with HIV by altering their gut microbiome and immune activation. The finding supports current WHO guidelines, which recommend long-term cotrimoxazole treatment for all HIV-positive people living in areas where malaria and severe bacterial infections are common. Previous studies have shown...
Source: Case Western Reserve University   Apr 04, 2019  6 years ago
Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities—they provide a haven for microbes and are often resistant to antibiotics. A new study describes a specific probiotic mix that could help patients with gastrointestinal diseases avoid harmful biofilms that ...
Source: American Geriatics Society  Apr 03, 2019  6 years ago
Acetaminophen (otherwise known by brand names such as Tylenol) is one of the most widely used pain relievers. Almost 60 years of widespread use have made acetaminophen a household product. It's distributed over the counter (OTC) in most countries and judged safe by the scientific community. However, acetaminophen is also one of the most common medications involved in overdoses (the medical ter...
Source: Eko Inc, Berkeley  Apr 02, 2019  6 years ago
Eko, a company that makes advanced and innovative stethoscopes that we really like, is now releasing its Eko DUO combination stethoscope/ECG device. The Eko DUO works along with a paired smartphone or tablet, allowing a physician to simultaneously record heart sounds and ECG (single lead) tracings at the point of care. The DUO makes it easy to capture ECG intervals and systolic time intervals...
Source: US FDA  Apr 02, 2019  6 years ago
The U.S. Food and Drug Administration has approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA. "Today's approval of Cimzia fulfills an unmet need for pa...
Source: Thailand Medical News  Apr 02, 2019  6 years ago
Siriraj Hospital in Thailand, lead by Dr Vuthinun Achariyapota announced at the recent Society Of Gynecologic Cancers (SGO) Annual Meeting 2019 in Hawaii of a new novel approach of detecting HPV via urine samples. HPV Virus   The group from Siriraj Hospital initially conducted a study from a sample size of about 96 women. In the study, two methods of detecting high-grade squamous intraepit...

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