Thailand Medical News

New cancer vaccine raises hopes for patients with HER2-positive cancers

Source: American Association for Cancer Research Oct 01, 2018 6 years ago

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial. Among 11 evaluable patients who had received more than the lowest dose of the vaccine, six (54 percent) had clinical benefit. One patient ...

The new focus shift from life extension to 'healthspan' extension.

Source:University of Illinois at Chicago Sep 18, 2018 6 years ago

Clinicians, scientists and public health professionals should proudly "declare victory" in their efforts to extend the human lifespan to its very limits, according to University of Illinois at Chicago epidemiologist S. Jay Olshansky. In an article published in the Journal of the American Medical Association, Olshansky writes that the focus should shift to compressing the "red ...

Mechanisms and Characteristics Of Circulating Tumor Cells Finally Uncovered.

Source:University of California, Los Angeles Sep 18, 2018 6 years ago

Scientists have long known that circulating tumor cells, rare cancer cells that are released into the bloodstream, have the potential to provide vital information about a person's specific cancer. But until now, they have been unable to reliably access information on how these cells behave. UCLA researchers have created a quick and effective mechanism to measure how these cells perform functio...

New analysis of about 4,000 mutations deliberately engineered into the BRCA1 gene to benefit breast or ovarian genetic screenings.

Source : University of Washington Health Sciences/UW Medicine Sep 18, 2018 6 years ago

Jay Shendure and Lea Starita, faculty in the Department of Genome Sciences at the University of Washington School of Medicine, are the senior authors. Shendure directs the Brotman Baty Institute for Precision Medicine in Seattle, which helped support the study. Starita co-directs the Brotman Baty Advanced Technology Lab. Shendure is also a Howard Hughes Medical Institute investigator. Greg Findla...

Brain scan study identifies factors of brain aging

Source: Journal of Alzheimer's Disease Sep 06, 2018 6 years ago

In the largest known brain imaging study, scientists from Amen Clinics (Costa Mesa, CA), Google, John's Hopkins University, University of California, Los Angeles and the University of California, San Francisco evaluated 62,454 brain SPECT (single photon emission computed tomography) scans of more than 30,000 individuals from 9 months old to 105 years of age to investigate factors that accelera...

Hormone therapy can make prostate cancer worse, study finds

Source: Cedars-Sinai Medical Center Sep 06, 2018 6 years ago

Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur. Prostrate Cancer Prostate cancer is the second-leading cause of cancer death i...

Growing Drug Resistance of Gonorrhea in the EU

Source: European Centre for Disease Prevention and Control (ECDC) Sep 06, 2018 6 years ago

Neisseria gonorrhoea continues to show high levels of resistance to azithromycin across the European Union and European Economic Area, according to the 2016 results of the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP). This threatens the effectiveness of the currently recommended dual therapy regimen for gonorrhoea. Overall, the rates of resistance to cefixime, ceftriax...

Department of Disease Control warns of Pinkeye Disease

Source: The Department of Disease Control, MOPH Aug 27, 2018 6 years ago

The Department of Disease Control is warning the public of pinkeye disease which is common during the rainy season, as about 60, 000 patients have suffered from the disease so far this year. According to Director-General of the Department Dr. Suwannachai Wattanayingcharoenchai, infections, allergies, and chemical reactions can cause pinkeye or conjunctivitis. The disease is not airb...

New Study to look at the Beneficial Effects of Coenzyme Q10 on Parkinson’s disease

Source: Kaneka Pharmaceuticals, Japan Aug 28, 2018 6 years ago

A recent article reviewing the research carried out so far into the effects of CoQ10 on the progressive debilitating disease- Parkinson's has revealed that a new phase III trial is scheduled to commence this year. In the past three years, demand for CoQ10 has escalated, causing soaring prices and reports of fake products entering the market. The increase in demand is thought to have been trigg...

HPV-related cancers on rise

Source: US Centers for Disease Control and Prevention Aug 28, 2018 6 years ago

Despite rising vaccination rates, cancers related to human papillomavirus, a common sexually transmitted infection, are on the rise in the United States, particularly cancers of the head, neck and throat, officials said Thursday. In men, most of the increase was in head, neck and throat cancers, while in women, cases of HPV-related anal cancer rose, according to a report ...

Researchers stop cell suicide that worsens sepsis, arthritis

Source: Case Western Reserve University Aug 28, 2018 6 years ago

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death. Cells often perforate their own membranes...

Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Source: Peptilogics, US Aug 28, 2018 6 years ago

Peptilogics, a development stage company utilizing its innovative peptide platform to treat multidrug-resistant bacterial infections, today announced it recently held a pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration (FDA) to discuss the regulatory pathway for the development of PLG0206 for the treatment of prosthetic joint infections (PJI). PJI is one of ...

Philips unveils EPIQ CVx cardiovascular ultrasound system

Source: Philips, Amsterdam Aug 28, 2018 6 years ago

Dutch technology company Royal Philips has unveiled its new cardiovascular ultrasound system EPIQ CVx to offer solutions for diagnostic, pediatric and interventional applications. The company used an EPIQ ultrasound platform to design the new system, which offers advanced image quality through a new generation organic light-emitting diode (OLED) monitor. The system uses ana...

Risk of HIV transmission increased by untreated Genital Warts

Source: Boston University School of Medicine Aug 28, 2018 6 years ago

A new study has shown that genital warts may promote HIV sexual transmission and, in turn, their treatment and prevention could help decrease the spread of the disease. HIV infecting a human cell. Credit: NIH Human Papillomavirus (HPV) is a common and highly infectious condition transmitted between persons during sexual skin-to-skin contact. It has more than 100 strains identified, with s...

Buying hospital inpatient (IPD) coverage in Thailand

Source: TMN Aug 28, 2018 6 years ago

Most medical insurance plans sold in Thailand, including those packaged with life insurance policies, focus on providing basic hospital Inpatient (IPD) coverage. With IPD coverage, a doctor has to admit you to the hospital to stay overnight. To get you admitted, the doctor has to certify that you have a medical problem that requires you to stay in the hospital at least one night. (While some insu...

Fibrates Gaining Favor for PBC

Source: University of Miami Miller School of Medicine Aug 28, 2018 6 years ago

With only two treatment options for primary biliary cholangitis, some hepatologists have cast a new eye on an older class of drugs. Fibrates, used for the treatment of dyslipidemia in the United States since the 1970s, had been shown to decrease levels of alkaline phosphatase (ALP), said Cynthia Levy, MD, FAASLD, an associate professor of medicine at the University of Miami Miller School of Medic...

Researchers identify protein that is responsible for cellular memory during cell division.

Source: University of Copenhagen The Faculty of Health and Medical Sciences Aug 28, 2018 6 years ago

With a new groundbreaking technique, researchers from University of Copenhagen have managed to identify a protein that is responsible for cellular memory being transmitted when cells divide. The finding is crucial for understanding development from one cell to a whole body. The cells in our body divide constantly throughout life. But how do cells remember whether to develop into a skin, liver or ...

Risk of polyneuropathy identified through new biomarkers of inflammation.

Source: Deutsches Zentrum fuer Diabetesforschung DZD Aug 28, 2018 6 years ago

Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes. First symptoms are often pins-and-needles sensations in the feet. Although polyneuropathy is present in about 30% of people with diabetes, it often remains undiagnosed. Scientists from the German Diabetes Center (DDZ) in D&uu...

High levels of HDL Cholesterol may be harmful

Source: European Society of Cardiology Aug 28, 2018 6 years ago

Very high levels of high-density lipoprotein (HDL or "good") cholesterol may be associated with an increased risk of heart attack and death, according to research presented today at ESC Congress 2018. HDL Cholesterol Study author Dr. Marc Allard-Ratick, of Emory University School of Medicine, Atlanta, US, said: "It may be time to change the way we view HDL cholesterol....

A new effective marker for cancer diagnosis and therapy developed.

Source: National University of Science and Technology MISIS Aug 28, 2018 6 years ago

A research group consisting of scientists from NUST MISIS, the Technical University of Munich, Helmholtz Zentrum München, the University of Duisburg-Essen, and the University of Oldenburg has developed a system that allows doctors to both improve the accuracy of diagnosing malignant cells and to provide additional opportunities for cancer treatment. The magnetoferritin compound is the main el...

Molecular link between aging and neurodegeneration

Source: Harvard Medical School Aug 28, 2018 6 years ago

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases. ...

Homeopathy is Useless and Dangerous. The debate about homeopathy is over. These verdicts prove it.

Source: University of Exeter Aug 28, 2018 6 years ago

I have made my views on homeopathy clear on many occasions — actually, I don’t see them as ‘views’ but as evidence-based statements. But this has never stopped the homeopathy brigade vehemently disagreeing with me. Not only that, they also claim that I cannot be trusted because I am biased, corrupt, incompetent and dishonest. Professor Edzard Ernst &...

Experimental Drug May Reverse Hair Loss, Hair Whitening and Skin Inflammation

Source: Johns Hopkins University School of Medicine Aug 28, 2018 6 years ago

An experimental drug can successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol, according to a new Johns Hopkins study in mice. The investigators say the compound halts the production of glycosphingolipids, or GSLs, that are major components of skin and other cell membranes. Current research shows that mic...

Folic acid supplements in pregnancy help kids of women with epilepsy

Source: Journal Neurology Aug 08, 2018 6 years ago

Drugs taken in pregnancy to prevent epilepsy seizures can raise the risk of language delays in children. But new research shows that folic acid supplements can cut that risk. One U.S. ob/gyn said the finding has real importance for his younger female patients. "The risk of language delay was decreased by half—the benefit of folic acid in this situation is...

Boys should be given HPV jab, says vaccine committee

Source: Cancer Research UK Aug 08, 2018 6 years ago

It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in the UK to help protect against the virus that causes most cases of cervical cancer. But until now, it has only been routinely offered to girls. Today, the Joint Committee for Vaccination and Immunisation (JCVI) recommended that adolescent boys should now also receive the vaccine. ...

Combining antibiotics changes their effectiveness

Source: European Molecular Biology Laboratory Aug 08, 2018 6 years ago

The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance. Combining antibiotics changes their effectiveness. In the first large-scale screening of its kin...

New Device to Diagnose Brain Injury

Source: University Of Geneva Aug 08, 2018 6 years ago

Brain injuries, particularly the milder ones, are difficult to accurately diagnose. CT scanners can help, but often they just don’t have the resolution for clinicians to identify unusual aberrations in the image. Moreover, they expose patients to radiation, are not always available, and the process of using them and evaluating the images produced can take quite some time before results are a...

Danger of HIV patients increasing Heart Failure rates by using Protease inhibitors

Source: Massachusetts General Hospital, Boston Aug 08, 2018 6 years ago

Raza M. Alvi, M.D., from Massachusetts General Hospital in Boston, and colleagues compared characteristics, cardiac structure, and outcomes in 394 persons with HIV and heart failure who were receiving PI (145 patients) versus non-PI (NPI; 249 patients) therapy. PI-based antiretroviral therapy contained boosted-dose ritonavir. Ritonavir-boosted protease inhibitor (PI) therapy is a...

Genome editing method targets AIDS virus

Source: Kobe University Aug 08, 2018 6 years ago

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells. Human immunodeficiency virus-1 (HIV-1) infection is a chronic disease affecting more than 35 million people worldwide. The infection can be controlled by antiretroviral therapy (ART), but the...

Eat high-fiber foods to reduce effects of stress on gut and behavior

Source: The Journal of Physiology Aug 08, 2018 6 years ago

Eating high fibre foods may reduce the effects of stress on our gut and behaviour, according to new research published in The Journal of Physiology. Stress is a significant health concern and can cause major changes in the gut and in the brain, which can cause changes in behaviour. In recent years there has been growing interest in the link between gut bacteria and stres...

New PET imaging method could track and guide therapy for type 1 diabetes

Source: Society of Nuclear Medicine and Molecular Imaging Aug 08, 2018 6 years ago

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography (PET) imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies. This study is reported in the featured article of the month in The Journal of Nuclear Medicine's August issu...

New Ultra-Sensitive Cardiac Troponin Blood Tests To Diagnose Heart Attacks

Source: American Heart Association Aug 08, 2018 6 years ago

A new test to assess a whether or not someone is having a heart attack upon arriving in the emergency room was safe and effective, ruling out heart attack in emergency room patients faster than a conventional method, according to new research in the American Heart Association's journal Circulation. The new high-sensitivity blood test for cardiac troponin, g...

New Novel Peptide Drug FFW to treat Liver Cancer

Source: National University Of Singapore Aug 08, 2018 6 years ago

A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma (HCC), or primary liver cancer. This landmark discovery opens the door for more effective treatment of liver cancer with less side effects. ...

Melbourne Scientists discover new anti-cancer drugs that can put cancer cells into a sleep state permanently

Source: Walter and Eliza Hall Institute of Medical Research Aug 08, 2018 6 years ago

New anti-cancer drugs put cancers to sleep—permanently In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies. Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work...

Arthritis severity gene identified

Source: Mount Sinai School Of Medicine Aug 08, 2018 6 years ago

A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition. Through a series of experiments -- on synovial cells from the inner lining of joints in humans...

Study Reveals That Aging can be reversed by “removing wrinkles inside our cells”

Source: University of Virginia Aug 08, 2018 6 years ago

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases—and possibly even turn back the clock on aging itself. Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty ...

New natural peptides that fight bacteria, reducing our need for antibiotics

Source: Technical University of Denmark Aug 08, 2018 6 years ago

For decades, researchers have been finding ways to fight disease-causing bacteria in food production without the use of antibiotics. This is because bacteria continuously become resistant to antibiotics due to repeated and improper use. In a study published in the journal PLOS One, researchers at the National Food Institute of the Technical University of Denmark ha...

2018 Review Of DermaPen

Source: Staff Writer, TMN Aug 08, 2018 6 years ago

Is DermaPen Safe? If you research dermabrasion or micro needling, you’ll eventually come across a little device called DermaPen. This type of tool has become a darling of many skin care professionals and aestheticians, who tout the product to their clients as a new solution for skin tightening, with little or no down time. However, although your local spa or dermatologist office may g...

A new class of drug to treat herpes simplex virus-1 infection

Source: Multiple Jul 22, 2018 6 years ago

For patients with the herpes simplex-1 virus (HSV-1), there are just a handful of drugs available to treat the painful condition that can affect the eyes, mouth and genitals. If patients develop resistance to these drugs, there are even fewer choices left to treat the infection, which lasts for life. BX795 Researchers at the University of Illinois at Chicago have now identified a ...

Finally, hope for a syphilis vaccine

Source: University of Connecticut Jul 21, 2018 6 years ago

Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible, UConn Health researchers report. The World Health Organization estimates that 10.7 million people between the ages of 15 and 49 had syphilis in 2012, and about 5.6 million people cont...

Chlamydia: Blockade at the receptor

Source: Multiple Jul 20, 2018 6 years ago

Chlamydia trachomatis is the main cause of sexually transmitted diseases. More than 131 million people are infected with this bacterium worldwide. If detected at an early stage and treated with antibiotics the infection with Chlamydia can be treated very well. However, infections with Chlamydia develop often without symptoms therefore in many cases remain unnoticed. This promotes the spread o...

Gonorrhea researchers identify novel route to vaccine, new antibiotic

Source: Multiple Jul 19, 2018 6 years ago

Researchers have identified a protein that powers the virulence of the bacteria that causes gonorrhea, opening the possibility of a new target for antibiotics and, even better, a vaccine. The microbe, Neisseria gonorrhoeae The findings, published today in PLOS Pathogens, are especially important since the microbe, Neisseria gonorrhoeae, is considered a "superbug" be...

HIV Vaccine Candidate 'Defines Additional Path' for Preclinical Data

Source: The Lancet Jul 22, 2018 6 years ago

Study paves way for better use of primate models in HIV vaccine development The mosaic vaccine HIV-1 vaccine produced comparable immune responses in both humans and rhesus monkeys, a phase I/IIa trial found. In humans, the vaccine was safe and produced antibody responses and T-cell responses, and in monkeys, the vaccine not only produced similar immune responses, but protected again...

Study shows how HIV is shielded from immune attack

Source: Multiple Jul 21, 2018 6 years ago

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host's immune system. Inositol hexakisphosphate fits into the pore structures (pink) of the HIV capsid (teal), and makes the makes the capsid stronger, protecting the genetic material inside. Credi...

Trogazo approved for multidrug-resistant HIV

Source: USFDA & Staff Writer, TMN Jul 19, 2018 6 years ago

A small percentage of patients, some of whom have taken many HIV drugs in the past, have multidrug-resistant HIV, limiting their treatment options HIV naturally mutates and eventually develops resistance to ARVs, which are then rendered ineffective. Patients infected with drug resistant strains of HIV are therefore commonly moved to alternative regimens known as 2nd line drugs. &n...

Lessons from Cancer drug that reactivates HIV can possibly lead to a new approach in HIV Cure

Source: Multiple Jul 18, 2018 6 years ago

People living with HIV must take a combination of three or more different drugs every day for the rest of their lives. Unfortunately, by following this strict treatment plan, they can suffer from side effects ranging from mild dizziness to life-threatening liver damage. However, if they stop taking the drugs, the virus hiding inside their cells can spontaneously resurface. In fact...

UK to Relax Immigration Rules for Non-EU Nurses, Says Report, Opportunities for English Speaking Thai Nurses

Staff Writer, TMN Jul 23, 2018 6 years ago

Britain's planned exit from the European Union is expected to result in restrictions on EU workers coming to the country, which could create further recruitment difficulties for the NHS. The British government will loosen immigration rules to allow more doctors and nurses from outside the European Union to come and work for Britain's National Health Service (NHS), the...

Yanhee Hospital Uses Nursing Aides On Rollerblades To expedite service!

Staff Writer, TMN Jul 22, 2018 6 years ago

In order to expedite service at its hospital, Yanhee Hospital has adopted the practice of getting its nursing aides to use rollerblades to deliver files, test results, x-ray films, prescriptions etc. However TMN staff observed that none were using helmets and safety gear and neither was there specific zones for them in the hospital , so hospital vissitors and patients need to be more careful! &nb...

Liver damage caused by OTC painkillers reduced by this folk remedy

Source: Universiti Putra Malaysia Jul 25, 2018 6 years ago

Over-the-counter painkillers like acetaminophen can damage the liver and cause serious health problems. A new study by Malaysian researchers suggested that compounds from a common fern can protect the liver from toxic acetaminophen. Every day, the liver gets exposed to various substances, many of them toxic. It normally detoxifies and expels those toxic chemicals, but...

High concentration peroxide ingestions can lead to life-threatening ailments and death

Source: University of Colorado School of Medicine Jul 24, 2018 6 years ago

High-concentration peroxide, sometimes promoted in alternative medicine circles for cleanses or as a so-called "natural cure," can lead to numerous life-threatening ailments and death itself, according to a paper published online yesterday in Annals of Emergency Medicine ("Outcomes Following High Concentration Peroxide Ingestions"). "Ingesting high-conce...

Reishi mushroom powder is an effective treatment for mouth ulcers

Source: Hunan Agricultural University Jul 23, 2018 6 years ago

The medicinal mushroom known as “Reishi ” in Japan was the subject of a recent Chinese study on alternative treatments for recurrent oral ulceration (ROU). The results showed that freeze-dried reishi mushroom powder provided effective treatment for the most prevalent mouth ulcer disease in the world. ROU is considered an autoimmune disease. It is a frequent complication fo...

Help for Stress Incontinence

Source: The Journal of the American Medical Association Jul 22, 2018 6 years ago

A new study suggests acupuncture could be effective About half of women ages 40 to 60 experience bladder leaks, or urinary incontinence, according to the American College of Physicians. And a condition called stress incontinence—leaking urine when you cough, sneeze, exercise, or laugh—is one of the most common types. Treatments, which often include drugs and surgery, can be ...

Study Questions the Use of Vitamin D Supplements in Heart Failure Patients

Source: European Heart Journal Jul 20, 2018 6 years ago

Experts urge caution with daily high-dose vitamin D supplements. More is not necessarily better when it comes to the use of vitamin D supplements in patients with heart failure, based on results of a recent study published in the European Heart Journal. Known as the EVITA (Effect of Vitamin D on All-Cause Mortality in Heart Failure) trial, this study looked at the impact of daily ...

Stem Cell Therapy Shows Promise for Patients with Chronic Heart Failure

Source: American Heart Association Jul 19, 2018 6 years ago

Stem cells from umbilical cords may improve heart function and symptoms. Stem cells from umbilical cords show promise as a treatment for heart failure, based on a recent study published in the American Heart Association journal Circulation Research. Known as the RIMECARD trial, this study tested stem cell therapy in 30 patients living with chronic heart failure. The goal was t...

Tea consumption leads to epigenetic changes in women

Source: Uppsala Universitet Jul 23, 2018 6 years ago

Epigenetic changes are chemical modifications that turn our genes off or on. In a new study, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact with cancer and estrogen metabolism. Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consum...

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