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Nikhil Prasad  Fact checked by:Thailand Medical News Team Dec 19, 2024  4 hours, 22 minutes ago

California Declares Emergency as H5N1 Becomes an Impending Public Health Threat

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California Declares Emergency as H5N1 Becomes an Impending Public Health Threat
Nikhil Prasad  Fact checked by:Thailand Medical News Team Dec 19, 2024  4 hours, 22 minutes ago
Medical News: Bird Flu Sparks Emergency Declaration
California has declared a State of Emergency due to the rapid spread of the H5N1 bird flu virus. This unprecedented move underscores the urgency of addressing the outbreak, which has now expanded beyond poultry to dairy herds in Southern California. Governor Gavin Newsom’s office announced the emergency following confirmation of cases in dairy cattle, highlighting the virus's alarming evolution.


California Declares Emergency as H5N1 Becomes an Impending Public Health Threat

“This proclamation ensures that state agencies have the flexibility and resources to act swiftly in response to this crisis,” Newsom stated. “Although the risk to the general public remains low, we are taking every possible step to contain the virus and mitigate its impact.” The declaration aims to bolster California’s monitoring and containment strategies, particularly as cases among dairy herds and humans continue to rise.
https://www.gov.ca.gov/2024/12/18/governor-newsom-takes-proactive-action-to-strengthen-robust-state-response-to-bird-flu/
 
The H5N1 strain, specifically clade 2.3.4.4b, has drawn global concern for its ability to spread across species. While traditionally associated with birds, this newer strain has been detected in mammals, including humans. Adding to these concerns is the emergence of another variant of the virus - the D1.1 genotype - which has been detected in wild birds, poultry, and recent human cases in North America.
 
The Outbreak at a Glance
Since the first detection of H5N1 in California’s dairy cattle in August, the outbreak has escalated significantly. According to Medical News updates, the state now accounts for 75% of all confirmed cases nationwide, with nearly 650 infected herds. In total, the virus has been identified in over 860 herds across 16 states. California’s dairy farms - an essential pillar of the U.S. milk supply - have become the epicenter of this crisis.
 
Human infections in the state are also rising. California has reported 35 confirmed or suspected cases this year, primarily among dairy and poultry workers.
 
Disturbingly, one case involved an individual with no known exposure to livestock or poultry, raising fears of alternative transmission routes. While the Centers for Disease Control and Prevention (CDC) maintains that the virus’s risk to the general public remains low, health experts warn that every human case represents an opportunity for the virus to adapt and become more transmissible.
 
The D1.1 Strain: A New Threat Emerges
Complicating the situation is the D1.1 strain of H5N1, which has been identified in wild birds, backyard poultry, and some human cases across North America. Genetic analysis of recent human infections, including a severe case in Louisiana, has traced the viru s to this genotype. Unlike the B3.13 genotype predominantly found in dairy cattle, the D1.1 strain appears to circulate in wild bird populations, raising concerns about its potential to spread more widely.
 
Dr. Demetre Daskalakis of the CDC highlighted the implications of the D1.1 genotype, stating, “This variant’s ability to infect multiple species and cause severe illness in humans underscores the importance of continuous genomic surveillance.” Experts warn that the presence of two distinct H5N1 genotypes in the U.S. complicates efforts to contain the outbreak, as each strain may require different strategies for monitoring and mitigation.
 
Louisiana’s Severe Case Raises Red Flags
The gravity of the H5N1 threat was further highlighted when a Louisiana resident was hospitalized with severe respiratory illness linked to bird flu.
https://www.thailandmedical.news/news/louisiana-reports-first-possible-human-case-of-h5n1
 
This individual, over 65 years old with preexisting conditions, is the first U.S. patient to experience such severe symptoms during the current outbreak. Genetic analysis revealed that the infection stemmed from the D1.1 strain, emphasizing its potential to cause more serious health outcomes compared to other variants.
 
“Sporadic severe cases are not unexpected, but they do indicate the potential for higher health risks,” said Dr. Daskalakis. Experts emphasize the need for vigilant monitoring and rapid intervention to prevent further escalation.
 
California’s Response to the Crisis
Governor Newsom’s emergency declaration enables state and local agencies to streamline their response efforts. Key measures include:
 
-Enhanced Testing: California leads the nation in testing and monitoring, recently expanding its efforts to include raw milk samples. This initiative aims to detect the virus before it reaches consumers.
 
-Resource Allocation: The emergency status allows for the rapid hiring of personnel and contracting of services critical for containment.
 
-Protective Equipment: Farmworkers in high-risk areas are receiving personal protective equipment (PPE) to reduce exposure.
 
Despite these efforts, challenges remain. Some farmers have resisted testing and containment measures, fearing economic repercussions. The state’s Central Valley, home to numerous dairies, has been particularly hard-hit, with recent detections forcing a shift from regional containment to a statewide approach.
 
Broader Implications of H5N1
Globally, the H5N1 virus has caused widespread devastation among poultry populations, with over 123 million birds culled since the outbreak began in 2022. The virus’s ability to jump species barriers has heightened concerns about a potential pandemic.
 
In the United States, the outbreak’s impact on the dairy industry marks a troubling development. Experts at the World Health Organization (WHO) and CDC have criticized the U.S. response as insufficient, citing voluntary testing protocols as a significant weakness. “Every untreated infection is an opportunity for the virus to evolve,” warned Dr. Amesh Adalja of the Johns Hopkins Center for Health Security.
 
What Lies Ahead
California’s emergency declaration is a critical step in containing the H5N1 outbreak, but it is only the beginning. The presence of both the B3.13 and D1.1 genotypes in the state highlights the complexity of the situation. Collaborative efforts at the state, federal, and international levels will be essential to controlling the virus and mitigating its impact on both human and animal populations.
 
Conclusion
As California battles the H5N1 outbreak, its emergency measures reflect the urgency of the situation. The virus’s spread to dairy cattle and the emergence of the D1.1 strain underscore the need for comprehensive monitoring, swift containment, and robust public health interventions. While the risk to the general public remains low for now, the evolving nature of H5N1 demands vigilance and cooperation across all sectors.
 
For the latest H5N1 News, keep on logging to Thailand Medical News.
 
Read Also:
https://www.thailandmedical.news/news/u-s-nih-study-discovers-q226l-mutation-which-enhances-binding-to-human-cells-in-h5n1-virus-strain-isolated-in-texas
 
https://www.thailandmedical.news/news/h5n1-bird-flu-adaptation-in-cats-in-south-dakota-as-a-lethal-neurotrophic-virus-raises-alarms
 
https://www.thailandmedical.news/articles/h5n1-avian-flu

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