COVID-19 Antibodies: Study Shows Passive Immunization Could Help Delay SARS-CoV-2 Progression, Boost Immunity In COVID-19 Patients Till Vaccine Arrives.
Source: COVID-19 Antibodies May 12, 2020 4 years, 6 months, 1 day, 16 hours, 4 minutes ago
COVID-19 Antibodies: Jordanian researchers from the Hashemite University say that utilizing antibodies from recovered patients has so far been life-saving for other acute infections and should be explored in detail in response to COVID-19 disease.
The global COVID-19 pandemic has infected more than 4.3 million people and killed close to 290,000 individuals. Developing a vaccine has become a world public health priority.
Creating a viable vaccine however might take a long time; medical researchers estimate a vaccine may be available in between 15 and 20 months. A potential interim solution reported in the International Journal of Risk & Safety in Medicine may be a passive vaccine, or passive immummization (PI), which can provide instant, short-term fortification against infectious agents.
https://content.iospress.com/articles/international-journal-of-risk-and-safety-in-medicine/jrs201017
Dr Foad Alzoughool, and his co-author, Dr Lo'ai Alanagreh, both from the Department of Laboratory Medical Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Jordan told Thailand Medical News, "Utilizing valuable plasma from recovered patients might be useful in our global war against COVID-19."
They have studied the application of Passive Immunization (PI) in previous pandemics and conclude that this approach is a potential solution to address the immediate health threat of COVID-19.
Typically, after exposure to a viral infection, an individual's body creates antibodies to fight off the virus. These antibodies in the blood of a recovered patient can be collected as convalescent plasma and transferred to the blood of a newly infected patient where it can neutralize the pathogen, eliminate it from the blood stream, and boost immunity.
Although Passive Immunization does not provide long-term protection against the virus, it can reduce the aggressiveness and mortality of an infection.
Usage of passive immunization dates to the beginning of the twentieth century during the Spanish flu epidemic, when individuals who received convalescent plasma serum had lower mortality rates than others.
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Studies of experimental usage of passive immunization during outbreaks of Ebola virus, chikungunya virus and the H1N1 flu also shows the potential of using passive immunization in the prevention and treatment of viral infections.
Also there has been evidence as well of the effectiveness of the technique in the SARS-CoV epidemic in Guandong, China and the MERS-CoV in Saudi Arabia, particularly if it is introduced soon after symptom onset.
It was reported that patients who received passive immunizati
on had a significantly shorter hospital stay and lower mortality than other groups. In another, patients who received convalescent plasma before day 14 of illness had a higher discharge rate.
Also medical workers who were infected with SARS-CoV and failed to respond to treatment survived after transfusion with convalescent plasma.
Dr Alanagreah added, "If you are looking for COVID-19 treatment, you will find it in the blood of survivors. In a time when no registered antiviral drug or vaccine is available, passive immunization might help in slowing down the deadly virus and save lives, particularly for the elderly and patients with pre-existing conditions."
So far, about 1.55 million people have recovered from the disease, and many of them would be willing to donate plasma to help slow down the pandemic. The medical researchers further explained that most importantly that practicing this method now will help health systems be prepared in case a second wave of disease occurs which is most likely according to many medical experts.
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