COVID-19 Hand Sanitizer: Biotech Startup CAGE Bio Launches Novel Hand Sanitizer Ionlast For COVID-19, With Long-lasting 4 Hours Plus Of Protection
Source: COVID-19 Hand Sanitizer Jul 24, 2020 4 years, 3 months, 3 weeks, 8 hours, 26 minutes ago
COVID-19 Hand Sanitizer: CAGE Bio Inc., a California based biotech startup announced discovery of a novel hand sanitizer that offers long-lasting protection from the SARS-CoV-2 coronavirus and other harmful viruses, bacteria, and fungi. It kills germs on contact and, unlike common hand sanitizers, provides protection against their transmission for more than four hours after applying to skin.
The biotech company that researches and develops ionic liquids for dermatology, inflammation and immunology, said that this innovation is a new class of hand sanitizers for a new threat. Its discovery contains ethyl alcohol to remove gross contamination and a proprietary ionic liquid technology that preserves an elevated state of hand protection for many hours.
The new hand sanitizer called IonLAST™, which is a patent-pending, four-plus hour protectant against harmful microbes, is far superior to common alcohol-based sanitizers, which haven't changed in decades and are typically effective for only a few minutes. Using CAGE Bio's ionic liquid technology, IonLAST forms a protective shield that lasts for several hours and provides protection that does not evaporate away.
Nitin Joshi, CEO of CAGE Bio told Thailand Medical News, "Long-lasting protection against the transmission of dangerous pathogens via hands will be helpful in many environments including nursing homes, restaurants, grocery stores, gyms and office workplaces. Long-lasting protection will play an important role in helping Americans get back to their lives, workplaces and routine activities as the country continue to reopen."
He added, "The average person touches their face 16 to 23 times every hour, often risking exposure to pathogens. While washing hands and following CDC prevention guidelines continues to be important, applying IonLAST after each washing or between washings is easy and delivers confidence by minimizing the risk of viral and bacterial transmission."
Dr Samir Mitragotri, the innovator of the ionic liquid technology, said, "Ionic liquids are particularly good at providing long-lasting protection. They are effective in killing a wide range of pathogens, and unlike conventional ethanol-based sanitizers, they don't simply evaporate away." Dr Mitragotri is Hiller Professor of Bioengineering and Hansjorg Wyss Professor of Biologically Inspired Engineering at John A. Paulson School of Engineering & Applied Sciences at Harvard University and Wyss Institute.
The biotech company created its proprietary formulation in response to the current COVID-19 pandemic. Following the initial discovery in CAGE Bio's lab, Joshi and his team validated the technology in an independent lab for killing viruses and providing duration protection in human volunteers. Clinical testing was conducted at BioScience Laboratories, Inc., in Bozeman, Mont.
A newly completed in-vitro GLP study results showed that IonLAST killed human coronavirus (hCoV229E) and generated a >40,000-fold reduction (≥ 99.99% reduction) in viral titers following 15-second exposure. Furthermore, an IRB-approved human study established the persistent antibacterial e
fficacy of IonLAST against Staphylococcus aureus with a remarkable >50,000-fold reduction (log
10 reduction ≥5.15) from the control following 30-minute, two-hour and four-hour post-product applications. Results from CAGE Bio's testing have been submitted for publication in bioRxiv.
The hand sanitizer IonLAST is manufactured using well established and commonly available naturally occurring compounds. The ionic liquid used in the formulation consists of natural compounds that are GRAS (generally recognized as safe) materials, which makes IonLAST safe and skin-friendly. Unlike common alcohol-only hand sanitizers, the extremely low volatility of this ionic liquid guards against rapid evaporation and allows IonLAST to remain on the skin to protect it for extended periods.
CAGE Bio’s CEO said a manufacturer in California is in the process of a pilot production run of IonLAST.
He added, "We are moving quickly to ramp up manufacturing and distribution and are speaking with a number of potential partners to bring this novel innovation to US consumers to maximize public benefit, combating the pandemic."
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