Huh! Study Published In Peer Reviewed Cell Discovery Journal Warns That COVID-19 Jabs Causes Pathophysiological Alterations Similar To An Actual Infection!
Source: Medical News Jan 31, 2022 2 years, 9 months, 3 weeks, 1 day, 14 hours, 15 minutes ago
The peer reviewed journal: Cell Discovery by Nature has published a study whose alarming findings are showing that current COVID-19 jabs are causing pathophysiological alterations similar to an actual SARS-CoV-2 Infection! The first actual study that focusses on the full pathological and immune profile of individuals after receiving COVID-19 jabs, (Note we cannot use the V word as certain algorithms used by certain American social media platforms and search engines will pick up the word and censor such articles as they are all part of the unscrupulous elites trying to control the COVID-19 narratives that will need to be dealt with and eradicated soon as the world wakes up.) is showing that such individuals are undergoing a variety of pathophysiological alterations in their bodies with many that can cause long term health and medical complications similar to those having Long COVID!
It should be noted that this study was actually conducted a result of Thailand
Medical News asking various research groups to do actual full immune profiles and laboratory pathological studies including key gene profiles on individuals before and after receiving these jabs. No such study was ever done prior to this.
The study findings show that receiving the COVID-19 jabs is literally no different from that of an actual infection in terms of the damage that is caused to the body.
The study team found besides generation of neutralizing antibodies, the bodies of the healthy individuals who volunteered for the study and received the COVID-19 jabs that contained the inactivated SARS-CoV-2 also had consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions.
Such similar changes had also been reported in COVID-19 patients, suggesting that receiving those COVId-19 jabs mimicked an infection.
More worryingly, single-cell mRNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) before and 28 days after the first jab also revealed consistent alterations in gene expression of many different immune cell types.
Furthermore, a reduction of CD8+ T cells and increase in classic monocyte contents were observed in all who got the jabs.
Also, scRNA-seq revealed increased NF-κB signaling and reduced type I interferon responses, which were confirmed by biological assays and these have also had been reported to occur after SARS-CoV-2 infection with aggravating symptoms.
The study team recommends additional caution when giving jabs to individuals with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.
In fact, the medical community should have enforced prior medical screening before even giving these jabs to any individuals.
(a) Clinical laboratory routine tests include hematologic and coagulation parameters, blood glucose-related and infection-related indices, lipid profile,
cardiac enzymes, electrolytes, liver- and renal function-related biomarkers. Laboratory test values of white blood cell count (b), HbA1c (c), potassium (d, left panel), sodium (d, right panel), APTT (e, left panel), PT (e, right panel), total cholesterol (f), total bile acid (g), eGFR (h, left panel), creatinine (h, right panel). Data points represent the values of each individual. Box plots showed the 25th, 50th (median), and 75th percentiles. Horizontal dashed lines showed upper normal limits (red) in b, c, d (left panels), e (left panel), f, h and the lower normal limits (blue) in d (left panel) and h. The P values were calculated by the Wilcoxon sign-rank test by comparing the laboratory measurements at each time with the baseline measurements. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.
But more concerning is the fact that these jabs can also subsequently trigger long term medical and health issues!
It is surprising that the Nature journal…Cell Discovery actually published this study as it is also a sign that many scientists, experts, physicians and even media are now waking up and seeing the effects of these jabs and also how the COVID-19 pandemic has been mismanaged by a few unscrupulous American, British, Canadian, Ethiopian and other European bastards that need to be eradicated as soon as possible or at least thrown into jail along with their families and supporters.
We suggest that readers copy and file the study as we expect that it might get removed soon.
https://www.nature.com/articles/s41421-021-00329-3
The study was conducted by researchers from Tongji University-Shanghai, China Second Military Medical University-Shanghai, China Chinese Academy of Sciences-Wuhan, Hubei and the University of Chinese Academy of Sciences-Beijing.
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Changes in peripheral immune cell type and subtype compositions as well as gene expression before and 28 days after the 1st jab.
a Cell-type UMAP representation of all merged samples. In total, 22 cell types were identified by cell-type-specific gene expression signatures. In total, 188,886 cells were depicted. b Dot plot for cell-type-specific signature genes. Color scale indicated expression levels and point size represented the percentage of cells per cluster/subtype expressing the corresponding gene. c UMAP representation representing cells before (blue) and after (orange) vaccination. d Heatmap of correlation amongst pseudo-bulk samples. e Percentages of specific immune cell subtypes in total PBMCs from each individual before and after vaccination. Box plot depicted sample distribution. Blue boxes represented samples before, and orange, after jabs. P values were based on the Wilcoxon test for comparisons between groups before and after jabs. f Box plots showed changes before and after jabs in monocyte content from scRNA-seq data (left panel) and clinical laboratory measures (right panel). g Box plots showed changes in CD4+, CD8+ T-cell contents as well as lymphocyte (T + B + NK) contents before and after jabs from scRNA-seq data (left 3 panels) and laboratory tests (right panel). h DEGs identified by pseudo-bulk samples before and after jabs. i Overrepresentation analysis of HALLMARK gene sets from MSigDB demonstrating different immunological features before and after jabs.
A total of 11 healthy adult volunteers of both sexes, aged 24–47 years, with a BMI of 21.5–30.0 kg/m², were enrolled in this study. SARS-CoV-2 jab (Vero Cell), inactivated (Beijing Institute of Biological Products Co. Ltd), was administered intramuscularly into the deltoid. Volunteers were divided into two cohorts; five participants (cohort A) were jabbed with a full dose (4 µg) of inactivated SARS-CoV-2 jab (Vero Cell) on days 1 and 14, and six participants (cohort B) received a full dose of the jabs on days 1 and 28.
Antibody and neutralizing antibody testing, immune profiles as well as detailed pathological clinical laboratory measurements before and at different times after the jabs were conducted.
Surprisingly the study findings showed consistent pathophysiological changes regarding electrolyte contents, coagulation profiles, renal function as well as cholesterol and glucose metabolic-related features, as if these individuals had experienced an infection with SARS-CoV-2.
These jabs also increased classical monocyte contents. Moreover, the gene set positively contributing to MVS scores, also known to be associated with severe symptom development, was highly expressed in monocytes. Also, PBMCs scRNA-seq results indicated consistent reductions in CD8+ T cells and increases in monocyte contents, as well as enhanced NF-κB inflammatory signaling, which also mimicked responses after infection.
Surprisingly, type I interferon (IFN-α/β) responses, which had been linked to reduced damages after SARS-CoV-2 infection and milder symptoms, appeared to be reduced after the jabs, at least by 28 days post the 1st jab.
In addition, the negative MVS genes were highly expressed in lymphocytes (T, B, and NK cells), yet showed reduced expression after jabs.
Together, these data suggested that after the jabs, at least by day 28, other than generation of neutralizing antibodies, people’s immune systems, including those of lymphocytes and monocytes, were perhaps in a more vulnerable state. and may require more protection.
Subtype-specific differential gene expression and gene set overrepresentation analyses depicting common gene expression changes amongst different types of immune cells after jabs.
a 11 major immune cell-type-specific DEGs identified by pseudo-bulk data produced by combinations of samples before and after jabs. Genes with logFC > 0.5 and adjust P < 0.05 were included. b Overrepresentation analysis of HALLMARK gene sets from MSigDB amongst 11 major cell types demonstrated common changes in gene sets representing altered immunological states before and after jabs. c, d UMAP visualization colored by average expression scores (levels) based on differential enrichment pathway. Box plot depicting the expression score distribution before and after jabs.
The detailed analyses presented in this study, particularly, scRNA-seq of PBMCs had not been performed for previous jab evaluations, whether the changes in immune system function-related genes were COVID-19-specific or could be generally applied to other jabs or other types of COVID-19 jabs remained to be determined.
However, these types of detailed analyses should be overall beneficial to jab development and applications.
Importantly the study findings postulate that it is imperative to consider the potential long-term impact of COVID-19 jabs to certain medical conditions or to general human health.
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