Nikhil Prasad Fact checked by:Thailand Medical News Team Jun 18, 2024 5 months, 3 days, 23 hours, 19 minutes ago
Thailand Aesthetics: Lactoferrin is an iron-binding protein found in the milk of most mammals, including humans. This protein is renowned for its anti-inflammatory, antibacterial, antiviral, and skin-repairing properties. Recent research has shown that lactoferrin could be a game-changer in skincare, offering benefits like improved skin barrier function, reduced inflammation, and enhanced hydration.
Lactoferrin: A New Player In The World Of Aesthetics And Skincare
How Lactoferrin Benefits Your Skin
Researchers from Pigeon Manufacturing (Shanghai) Co., Ltd. explored the potential of lactoferrin in skincare using a recombinant human epidermal model. Their study findings are covered in this
Thailand Aesthetics report.
Study Findings:
-Anti-Inflammatory Properties: Lactoferrin significantly reduces the levels of inflammatory markers IL-1α and TSLP in the skin. This means it can soothe irritated skin and reduce redness and swelling, making it ideal for those with sensitive or inflamed skin conditions.
Skin Barrier Enhancement: Lactoferrin boosts the expression of key skin barrier proteins like AQP3, Filaggrin, and Involucrin. These proteins are crucial for maintaining a healthy skin barrier, which protects against environmental aggressors and retains moisture.
Moisturization: By enhancing the expression of Aquaporin-3 (AQP3) and Hyaluronic Acid Synthase 1 (HAS1), lactoferrin improves the skin's ability to retain moisture, leading to better hydration and a plumper, more youthful appearance.
The Science Behind the Magic
The study involved culturing human epidermal keratinocyte cells and treating them with varying concentrations of lactoferrin. The results were impressive:
-Improved Cell Viability: Lactoferrin did not harm the skin cells even at high concentrations, indicating its safety for topical use.
-Reduced Inflammation: At concentrations of 1.5 mg/mL and above, lactoferrin significantly decreased the release of inflammatory cytokines IL-1α and TSLP.
-Enhanced Barrier Function: The Transepidermal Electrical Resistance (TEER) of the skin was significantly enhanced with lactoferrin treatment, indicating a stronger skin barrier.
-Increased Protein Expression: Lactoferrin boosted the expression of skin barrier proteins, contributing to better skin health and appearance.
Why This Matters
The skin is our largest organ and our first line of defense against environmental damage. A healthy skin barrier is essential for protecting against pollutants, bacteria, and other harmful agents. Lactoferrin's ability to enhance this barrier makes it a valuable ingredient
in aesthetic protocols or skincare products, particularly for those with sensitive or compromised skin.
Real-World Applications
The findings from this study suggest that lactoferrin could be incorporated into a variety of skincare products, including creams, lotions, and serums. Its multi-functional benefits make it a versatile ingredient for addressing various skin concerns, from dryness and sensitivity to aging and inflammation.
Future Directions
While the current study provides a strong foundation for the use of lactoferrin in skincare, further research and clinical trials are needed to fully understand its potential and optimize its applications. As the demand for natural and effective skincare solutions grows, lactoferrin is poised to become a key player in the industry.
Conclusion
Lactoferrin offers promising benefits for skincare, including anti-inflammatory effects, enhanced barrier function, and improved hydration. As research continues, we can expect to see more lactoferrin-infused products hitting the shelves, providing consumers with a powerful tool for maintaining healthy, beautiful skin.
The study findings were published in the peer reviewed journal: Cosmetics.
https://www.mdpi.com/2079-9284/11/3/98
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