Long COVID News: British Study Shows That 59 Percent Of Long COVID Patients Suffer From Organ Damage Up To One Year After Disease Onset!
Long COVID News - Organ Damage Feb 15, 2023 1 year, 9 months, 1 week, 16 hours, 48 minutes ago
Long COVID News: More great news emerging especially for COVID minimizers and morons that insist that COVID-19 is similar to flu.
A new study by researchers from the United Kingdom has found that 59% of Long COVID patients experience organ damage up to one year after the onset of the disease!
The study consisted of medical researchers from:
-University of Liverpool, Liverpool
-Hull and East Yorkshire Hospitals NHS Foundation Trust, Hull
-University of Hull, Hull
-Perspectum, a biotechnology company based in Oxford
-John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust,
-Long Covid SOS, Faringdon,
-UKDoctors#Longcovid, London
-University College London Hospitals NHS Foundation Trust, London,
-University College London, London
-Barts Health NHS Trust, London
The study team aimed to determine the prevalence of organ impairment in long COVID patients at 6 and 12 months after initial symptoms and to explore links to clinical presentation involving a prospective cohort study that consisted of Long COVID patients at two non-acute healthcare settings (Oxford and London).
https://clinicaltrials.gov/ct2/show/NCT04369807
The study team assessed symptoms, health status, and multi-organ tissue characterization and function in individuals recovered from acute COVID-19. Physiological and biochemical investigations were performed at baseline on all individuals, and those with organ impairment were reassessed.
Primary outcome was prevalence of single or/and multi-organ impairment at 6- and 12-months post COVID-19.
A total of 536 individuals (mean age 45 years, 73% female, 89% white, 32% healthcare workers, 13% acute COVID-19 hospitalization) completed baseline assessment (median: 6 months post COVID-19); 331 (62%) with organ impairment or incidental findings had follow-up, with reduced symptom burden from baseline (median number of symptoms 10 and 3, at 6 and 12 months, respectively).
Extreme breathlessness (38% and 30%), cognitive dysfunction (48% and 38%) and poor health-related quality of life (EQ-5D-5L < 0.7; 57% and 45%) were common at 6 and 12 months, and associated with female gender, younger age and single-organ impairment. Single- and multi-organ impairment were present in 69% and 23% at baseline, persisting in 59% and 27% at follow-up, respectively.
The study findings showed that organ impairment persisted in 59% of 331 individuals followed up at 1 year post COVID-19, with implications for symptoms, quality of life and longer-term health, signaling the need for prevention and integrated care of long COVID.
The study findings were published in the peer reviewed Journal of the Royal Society of Medicine.
https://journals.sagepub.com/doi/10.1177/01410768231154703
This is the first comprehensive study of organ impairment in long COVID patients over 12 months that showed organ damage persisted in 59% of patients a year after initial symptoms, even in those not severely affected when first diagnosed with the virus.
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The research focused on patients reporting extreme breathlessness, cognitive dysfunction and poor health-related quality of life. 536 long COVID patients were included in the study. 13% were hospitalized when first diagnosed with COVID-19. 32% of people taking part in the study were healthcare workers.
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Shockingly, of the 536 patients, 331 (62%) were identified with organ impairment six months after their initial diagnosis. These patients were followed up six months later with a 40-minute multi-organ MRI scan (Perspectum's CoverScan), analyzed in Oxford.
The study findings confirmed that 29% of patients with long COVID had multi-organ impairment, with persistent symptoms and reduced function at six and twelve months. 59% of long COVID patients had single organ impairment 12 months after initial diagnosis.
Dr Amitava Banerjee, a Professor of Clinical Data Science at the University College London’s Institute of Health Informatics and a member of the study team told Long COVID News staff at Thailand Medical News, "Symptoms were common at six and twelve months and associated with female gender, younger age and single organ impairment."
The research findings reported a reduction in symptoms between six and 12 months (extreme breathlessness from 38% to 30% of patients, cognitive dysfunction from 48% to 38% of patients and poor health-related quality of life from 57% to 45% of patients).
Dr Banerjee further added, "Numerous studies confirm persistence of symptoms in individuals with long COVID up to one year. We now add that three in five people with long COVID have impairment in at least one organ, and one in four have impairment in two or more organs, in some cases without symptoms."
He also added, "Impact on quality of life and time off work, particularly in healthcare workers, is a major concern for individuals, health systems and economies. Many healthcare workers in our study had no prior illness, but of 172 such participants, 19 were still symptomatic at follow-up and off work at a median of 180 days."
The study team however said that the underlying mechanisms of long COVID remain elusive, as they did not find evidence by symptoms, blood investigations or MRI to clearly define long COVID subtypes. They say that future research must consider associations between symptoms, multi-organ impairment and function in larger cohorts.
The study team concluded, "Organ impairment in long COVID has implications for symptoms, quality of life and longer-term health, signaling the need for prevention and integrated care for long COVID patients."
It is even more interesting as Governments and health authorities across the world under the pressure of those controlling the COVID-19 narratives insist that the disease is now endemic and mild and that the people have to learn to live with the virus and try to conceal or underplay all infection and death rates while more than 800 newly emerged SARS-CoV-2 subvariants and sub-lineages ‘silently’ infect or reinfect the masses, in many cases asymptomatically or mildly symptomatically except for those in the vulnerable groups, we can expect to see more sick people with debilitating health conditions and an exponential increase in excess death rates. It is a good time to invest in certain pharma stocks and companies manufacturing essential medical equipment but not in hospitals as many doctors and healthcare professionals themselves are expected to die!
For the latest Long COVID News, keep on logging to Thailand Medical News.
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