Source: Thailand Medical News Jan 03, 2020 4 years, 11 months, 2 weeks, 4 days, 19 hours, 46 minutes ago
Cardiac or
heart problems are a common development for people with
diabetes. In fact, about 35% of people globally are admitted to the hospital for
heart failure also have
diabetes.
Heart failure may be the result of a co-condition, such as hypertension or coronary
heart disease, but not always.
A new study published in
Mayo Clinic Proceedings,
Diabetes Mellitus Is an Independent Predictor for the Development of
Heart Failure: A Population Study, examines the idea of
diabetic cardiomyopathy and
heart failure from the effects of
diabetes alone.
Using the Rochester Epidemiology Project, researchers evaluated the long-term impact of
diabetes on the development of
heart failure, both with preserved ejection fraction a measurement of the percentage of blood leaving the
heart with each contraction and reduced ejection fraction. They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function. Dr Horng Chen, M.D., cardiologist at Mayo Clinic in Rochester, Minnesota, is senior author of the study.
For the study, an initial group of 2,042 residents of Olmsted County, 116 study participants with
diabetes were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without
diabetes. Over the 10-year follow-up period, 21% of participants with
diabetes developed
heart failure, independent of other causes. In comparison, only 12% of patients without
diabetes developed
heart failure. Cardiac death,
heart attack and stroke were not statistically different in the study between the two groups.
The research findings show that
diabetes is an independent risk factor for the development of
heart failure in the community dwelling population. Furthermore, the outcome data support the concept of a
diabetic cardiomyopathy.
This new research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction,
diabetic patients are still at increased risk of developing
heart failure as compared to their nondiabetic counterparts.
Dr. Chen told
Thailand Medical news, "The key takeaway is that
diabetes mellitus alone is an independent risk factor for the development of
heart failure. Our hope is that this study provides a strong foundation for further investigations into diabetes and
heart failure
rong>. There is still much to learn and study in terms of this association and how to best diagnose and treat this condition."
Reference : Diabetes Mellitus Is an Independent Predictor for the Development of Heart Failure, Michael D. Klajda, MD, Christopher G. Scott, MS, Richard J. Rodeheffer, MD, Horng H. Chen, MB BCh, Mayo Clinic Proceedings DOI: https://doi.org/10.1016/j.mayocp.2019.07.008 
