Nikhil Prasad Fact checked by:Thailand Medical News Team Dec 05, 2024 6 days, 16 hours, 56 minutes ago
Medical News: A new study sheds light on a lesser-known aftereffect of COVID-19 infection. Conducted by researchers from Qilu Hospital of Shandong University and Shandong Rongjun General Hospital in China, the investigation focused on a unique post-COVID-19 condition: recurrent fever associated with autonomic dysfunction. This condition, which involves the autonomic nervous system responsible for involuntary body functions, can cause serious disruptions.
The study observed seven patients who, after recovering from COVID-19, experienced recurring fever with no evident cause.
Post COVID Fever and Autonomic Dysfunction
What Is Autonomic Dysfunction?
Autonomic dysfunction, or dysautonomia, occurs when the autonomic nervous system malfunctions. This system controls essential processes like heart rate, blood pressure, digestion, and body temperature. In these patients, symptoms included recurrent fever, dizziness, sleep disturbances, and abnormalities like increased sweating or orthostatic hypotension, a condition where blood pressure drops when standing up.
The researchers pointed out that many people infected with COVID-19 recover fully. However, some face long-term symptoms collectively known as post-COVID-19 condition, or long COVID. This can manifest weeks or months after the initial infection. Among the seven patients, fever was the primary symptom tied to this form of autonomic dysfunction.
Study Details and Methodology
The retrospective study took place from January to March 2023. All participants were hospitalized with fever lasting more than four weeks without any other diagnosis. The study aimed to explore the link between COVID-19 and these prolonged symptoms.
Patients underwent extensive testing, including physical examinations, blood analyses, and scans. Autonomic function was evaluated using a thermoregulatory sweat test, cardiovascular reflex tests, and other methods. All patients tested positive for signs of autonomic dysfunction.
Key Findings
One of the most striking results was the uniformity of autonomic dysfunction symptoms. All seven patients displayed sweating abnormalities, indicating problems with temperature regulation. Blood pressure and heart rate irregularities were also common, confirming autonomic involvement.
Additionally, all patients had low sodium levels, known as hyponatremia. This abnormality often coincided with fever episodes, suggesting a potential link. While the exact mechanisms remain unclear, the researchers hypothesize that damage to the autonomic nervous system by the COVID-19 virus might disrupt the body's ability to regulate temperature and fluid balance.
Recurrent Fever and Treatment Approaches
The study noted that the interval between the initial COVID-19 infection and the onset of recurrent fever varied. In some cases, fever began immediately, while in others, there was a gap of several weeks. Importantly, no bacterial or viral infections were identified in these patients.
Treatment focused on managing symptoms. Cooling methods, like using ice packs, helped lower fever. Electrol
yte imbalances were corrected through sodium and potassium supplementation. This approach proved effective for most patients, though some required ongoing care.
Why Is This Important?
The study highlights a unique subset of long COVID cases. It emphasizes that autonomic dysfunction can manifest in various ways, and fever could be a telltale sign. For clinicians, understanding this relationship is vital to providing appropriate care.
This
Medical News report also underscores the need for more awareness about post-COVID conditions. As the pandemic continues to evolve, long-term effects like autonomic dysfunction warrant more attention and research.
What This Means for Patients
If you or someone you know has recovered from COVID-19 but continues to experience unexplained fever, fatigue, or other symptoms, it’s important to seek medical advice. Conditions like autonomic dysfunction are manageable with proper care. Awareness is key to identifying and treating these symptoms early.
Conclusion
The findings from this study bring attention to an underexplored area of post-COVID care. Autonomic dysfunction may be a driving factor behind recurrent fever in some patients, presenting new challenges for healthcare providers. The researchers recommend further studies to validate their findings and explore the mechanisms involved. By doing so, medical professionals can better understand the intricacies of long COVID and improve treatment strategies for affected individuals.
For now, the message is clear: post-COVID conditions can take many forms, and fever combined with autonomic dysfunction might be one of them. Healthcare systems must adapt to address these lingering effects, ensuring that every patient has the opportunity for full recovery.
The study findings were published in the peer-reviewed journal: Annals of Medicine.
https://www.tandfonline.com/doi/full/10.1080/07853890.2024.2402943
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https://www.thailandmedical.news/news/breaking-covid-19-new:-european-meta-study-validates-that-sars-cov-2-infections-can-cause-cardiovascular-autonomic-dysfunction-in-many
https://www.thailandmedical.news/news/coronavirus-news-mayo-clinic-study-shows-that-covid-19-can-cause-dysautonomia