The Probiotic Streptococcus Salivarius BLIS K12 for Preventing and Modulating Viral Infections
Nikhil Prasad Fact checked by:Thailand Medical News Team Feb 10, 2025 19 hours, 59 minutes ago
Medical News: A Natural Probiotic with Promising Benefits
Researchers from Blis Technologies Ltd in New Zealand have been studying a unique probiotic known as Streptococcus salivarius BLIS K12. This naturally occurring bacterium, found in the human mouth, has been recognized for its ability to inhibit harmful bacteria. Now, scientists are exploring its potential to help prevent viral infections, including those affecting the respiratory system.
The Probiotic Streptococcus Salivarius BLIS K12 for Preventing and Modulating Viral Infections
This
Medical News report delves into how BLIS K12, which was initially developed for its antibacterial properties against Streptococcus pyogenes, is showing promise in supporting immune responses and potentially reducing the impact of viral infections such as COVID-19. The latest findings suggest that BLIS K12 plays a role in regulating inflammation, supporting mucosal immunity, and even modulating antibody responses against viral antigens.
How BLIS K12 Helps Fight Infections
BLIS K12 produces specialized antimicrobial substances called bacteriocins, which help maintain a balanced microbial environment in the mouth and throat. These bacteriocins, specifically salivaricin A2 and salivaricin B, have been found to inhibit the growth of harmful bacteria such as Streptococcus pneumoniae and Moraxella catarrhalis, both of which are associated with respiratory infections.
Beyond its antibacterial role, research suggests that BLIS K12 may also support the immune system by modulating inflammatory responses. Infections, particularly viral ones, can sometimes trigger excessive inflammation, leading to severe complications. Studies have shown that BLIS K12 may help regulate immune responses, reducing the severity of conditions linked to viral infections.
Evidence of Antiviral Potential
Several clinical trials have explored the antiviral properties of BLIS K12. In one study, children taking BLIS K12 had a significantly lower incidence of viral pharyngotonsillitis compared to those who did not receive the probiotic. Another study observed that individuals hospitalized with COVID-19 who received BLIS K12 supplementation showed reduced need for oxygen support and experienced better overall recovery compared to those who did not.
Researchers have also suggested that BLIS K12 may support the production of antibodies against viruses. A recent study found that individuals with higher levels of Streptococcus salivarius in their oral microbiome exhibited stronger antibody responses to the SARS-CoV-2 spike protein after vaccination. This raises the possibility that BLIS K12 may enhance vaccine effectiveness or offer some level of immune protection against certain viruses.
Supporting Respiratory Health
Secondary bacterial infections often worsen the effects of viral illnesses such as influenza and COVID-19. BLIS K12 may help prevent these complications by maintaining a healthy microbial balance in the mouth and upper respiratory
tract. By limiting the growth of harmful bacteria, BLIS K12 could reduce the risk of bacterial superinfections, which are a common cause of severe respiratory complications.
Maintaining a well-balanced microbiome is crucial for overall immune defense. Studies have confirmed that BLIS K12 supplementation does not disrupt the natural diversity of beneficial bacteria, making it a safe and effective addition to immune health strategies.
The Future of BLIS K12 in Infection Prevention
The ability of BLIS K12 to influence immune responses, reduce bacterial infections, and potentially support antiviral defenses positions it as a valuable tool in infection prevention. While more extensive clinical studies are needed to confirm these benefits, the existing research indicates that this probiotic could play a significant role in maintaining respiratory health and improving immune resilience against infections.
Conclusion
The emerging evidence on Streptococcus salivarius BLIS K12 highlights its potential as a natural, non-pharmaceutical approach to preventing and modulating viral infections. By enhancing mucosal immunity, reducing bacterial infections, and possibly influencing antibody responses, BLIS K12 offers a promising addition to immune health strategies. Future research will be essential to fully understand its antiviral capabilities and its role in protecting against respiratory illnesses. Given its safety and potential health benefits, BLIS K12 may become an important part of preventive healthcare, particularly for those at higher risk of infections.
The study findings were published in the peer-reviewed journal: Applied Microbiology.
https://www.mdpi.com/2673-8007/5/1/7
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