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Nikhil Prasad  Fact checked by:Thailand Medical News Team Mar 20, 2024  9 months, 2 days, 18 hours, 42 minutes ago

University Of Cambridge Scientists Admit That Current mRNA COVID Jabs Causes Unintended Immune Responses In Up To One Third Of Recipients!

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University Of Cambridge Scientists Admit That Current mRNA COVID Jabs Causes Unintended Immune Responses In Up To One Third Of Recipients!
Nikhil Prasad  Fact checked by:Thailand Medical News Team Mar 20, 2024  9 months, 2 days, 18 hours, 42 minutes ago
COVID-19 News: In a shocking revelation based on study findings, scientists at the prestigious University of Cambridge have unearthed a previously unknown facet of mRNA-based therapeutics, particularly in the context of mRNA vaccines like those developed to combat the COVID-19 pandemic. This revelation covered in this COVID-19 News report comes at a crucial juncture in medical science, where the potentials of mRNA technology have been hailed as revolutionary yet accompanied by nuanced safety considerations that demand meticulous attention and further exploration.


Current COVID-19 mRNA vaccines generate unintended proteins that can
lead to unintended immune responses in up to one third of recipients! No
one knows what are the long term consequences of these proteins!

 
The study team discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body as a result of unintended proteins being produced! They have identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses to enable the safer design of future mRNA therapeutics. This discovered was made only in December 2023 which means that billions of people received the current mRNA vaccines which have yet to be modified to prevent this! Also, there are no studies to assess what effects these unintended proteins can have on the human hosts in the short or long term! (Note proteins can interfere with numerous enzymes, genes, cellular and signaling pathways etc in the humans and can cause various issues spanning from cancers to neurodegenerative issues, cardiac issues etc! Simply discounting that these proteins can have an effect on the human host without any proper detailed investigations or studies and and making statements that there cause of  "no ill effects" without proper data is simply not right nor ethical.
 
When contacted, the various mRNA vaccine manufacturers are refusing to comment or issue a statement on this study findings and the researchers from University of Cambridge insist that they rather not talk about it but rather focus on ways to make the future mRNA vaccines better and safer!
 
Decoding the Intricacies of mRNA and Its Impact on Vaccine Development
To comprehend the significance of this discovery, one must delve into the intricate workings of mRNA, commonly referred to as messenger ribonucleic acid. Essentially, mRNA serves as the genetic blueprint that guides cells in the body to produce specific proteins. This technology has been a game-changer, especially in vaccine development, as exemplified by the swift creation and deployment of mRNA-based vaccines against the SARS-CoV-2 virus, which causes COVID-19.
 
The pioneering work of biochemists such as Dr Katalin Karikó and immunologists like Dr Drew Weissman has been instrumental in harnessing the power of mRNA to prompt the human immune system to recognize and combat pathogens effectively. Their groundbreaking di scoveries paved the way for the development of mRNA vaccines that have proven highly effective in controlling the spread of infectious diseases.
 
Unveiling the Slippery Slope: Off-Target Immune Responses in mRNA Therapy
However, amidst the triumphs of mRNA technology, researchers at the University of Cambridge have delved into a lesser-known aspect - the potential for unintended immune responses triggered by mRNA therapeutics. Led by esteemed biochemist Professor Anne Willis and accomplished immunologist Dr James Thaventhiran from the Medical Research Council (MRC) Toxicology Unit, this research endeavor has brought to light a phenomenon that could influence the safety and efficacy of future mRNA-based treatments.
 
At the core of their discovery lies the 'slipping' of the cellular machinery responsible for decoding mRNA sequences. When faced with repeats of a chemical modification known as N1-methylpseudouridine, a common feature in mRNA therapeutics, the cellular machinery can 'slip,' leading to the production of unintended proteins. This unintended protein production, in turn, can trigger an immune response that was not originally intended or anticipated.
 
Navigating the Waters of Safety: Insights from Clinical Studies
To substantiate their findings, the research team conducted a comprehensive study involving individuals who had received the mRNA Pfizer vaccine against COVID-19. Their findings were both insightful and, in some ways, surprising.
 
Among the cohort of vaccinated individuals, approximately one-third exhibited an unintended immune response triggered by the mRNA vaccine. Importantly, despite this immune response, no adverse effects or health complications were reported, aligning with the robust safety profile established by extensive clinical trials and real-world data on COVID-19 mRNA vaccines.
 
Questions Now Being Asked About These Presence of These Unintended Proteins In The Human Host After Vaccination!
Many other scientists, researchers and doctors are now asking for more details about these unintended proteins including the list of these proteins and also as to whether any studies have been done to monitor the effects of these proteins on the human host over time. Proteins play key roles in various enzyme activities including their upregulation, downregulation and even dysregulation and also can bind to other key proteases or even affect signaling pathways, gene issues etc.
 
The fact that new proteins are being introduced into a human host should not be dismissed as something normal and statements such as not causing any ill-effects are very vague!
 
The scientist also commented that they have found solutions to make the next generation vaccines better but what about the billions who had been getting these vaccines before December 2023 when this discovery was made!
 
Engineering Solutions: Redesigning mRNA Sequences for Safety and Efficacy
Armed with these revelations, the University of Cambridge researchers embarked on a mission to devise strategies that could mitigate the risk of off-target immune responses in mRNA therapeutics. Their innovative approach involved redesigning mRNA sequences to circumvent the 'slipping' phenomenon observed during the decoding process. By fine-tuning the genetic sequences, they successfully achieved the intended protein production without triggering unintended immune reactions.
 
Conclusions
The discovery of the fact that unintended immune responses and unintended proteins are being generated by these current mRNA COVID-19 vaccines is actually an alarming discovery and even the researchers from Cambridge University under pressure to downplay the seriousness of their discovery used terms such as the need to find solutions to come up with second generation mRNA vaccines that can “prevent potentially harmful immune responses”!
 
More urgent studies are warranted to first identify and list all the unintended proteins that these current mRNA COVID-19 vaccines can cause and then detailed studies are needed to see what each and every one of these proteins can do in the human hosts.
 
Statements like "no ill effects” should be questioned and the vaccine manufacturers need to be more forthcoming with details and what they know.
 
The details about this discovery can be found here:
https://www.cam.ac.uk/research/news/researchers-redesign-future-mrna-therapeutics-to-prevent-potentially-harmful-immune-responses
 
The study findings were published in the peer reviewed journal: Nature.
https://www.nature.com/articles/s41586-023-06800-3
 
Unfortunately, most common people do not understand the findings of the study and even understand how unintended proteins being produced in a human host can have serious implications even for long term health issues!
 
For the latest COVID-19 News, keep on logging to Thailand Medical News.

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